Page last updated: 2024-11-01

nicardipine and Aneurysm, Thoracic Aortic

nicardipine has been researched along with Aneurysm, Thoracic Aortic in 5 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takaba, T1
Yokokawa, H1
Moriyasu, K1
Matsuo, Y1
Nishikawa, T1
Kataoka, D1
Minato, N1
Itoh, T1
Natsuaki, M1
Furukawa, K1
Rikitake, K1
Yamamoto, H1
Shinpo, H1
Mizumoto, T1
Shimono, T1
Shikano, K1
Takeuchi, Y1
Tanaka, K1
Yada, K1
Yuasa, H1
Kusagawa, M1
Hirotani, T2
Kato, Y1
Shirota, S2
Kameda, T2
Mayuzumi, S1
Kumamoto, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
NICardipine Neuroprotection in AortiC Surgery (NICNACS)[NCT00508118]Phase 27 participants (Actual)Interventional2008-01-31Terminated (stopped due to 3/7 subjects experienced hypotension. Study was terminated.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration From Initiation of Cardiopulmonary Bypass (CPB) to Electrocerebral Silence (ECS), Defined as no Discernable Electroencephalographic Activity at an Amplification of 2 Micro Volts (μV)/mm, Confirmed for 3 Minutes

(NCT00508118)
Timeframe: Day of surgery

InterventionTime (minutes) (Median)
NICARDIPINE GROUP45

Other Studies

5 other studies available for nicardipine and Aneurysm, Thoracic Aortic

ArticleYear
[Antihypertensive therapy using nicardipine hydrochloride in the treatment of aortic aneurysm].
    Kyobu geka. The Japanese journal of thoracic surgery, 1995, Volume: 48, Issue:4

    Topics: Adult; Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Female; Heart Rate; Humans; Hypertension;

1995
Perioperative coronary artery spasm in modified Bentall's operation for annulo-aortic ectasia in Marfan's syndrome. A case report of perioperative chordal rupture of the mitral valve.
    The Journal of cardiovascular surgery, 1995, Volume: 36, Issue:2

    Topics: Angina Pectoris, Variant; Aortic Aneurysm, Thoracic; Aortic Valve Insufficiency; Chordae Tendineae;

1995
[Selective cerebral perfusion and pharmacological cerebral protection in the patients with aortic arch aneurysm].
    Kyobu geka. The Japanese journal of thoracic surgery, 1993, Volume: 46, Issue:8 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood

1993
[Surgical treatment of type A acute aortic dissection--experience of hypothermic circulatory arrest associated with the cerebroplegia].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1997, Volume: 45, Issue:4

    Topics: Acute Disease; Adult; Aged; Aortic Aneurysm, Thoracic; Aortic Dissection; Blood Vessel Prosthesis; C

1997
Aortic arch repair using hypothermic circulatory arrest technique associated with pharmacological brain protection.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2000, Volume: 18, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aortic Aneurysm, Thoracic; Aortic Dissection; Aortic Rupture; Blood

2000