nicardipine has been researched along with Aneurysm, Ruptured in 13 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Aneurysm, Ruptured: The tearing or bursting of the weakened wall of the aneurysmal sac, usually heralded by sudden worsening pain. The great danger of a ruptured aneurysm is the large amount of blood spilling into the surrounding tissues and cavities, causing HEMORRHAGIC SHOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using a propensity-score model, this patient cohort was compared to patients in the Subarachnoid Hemorrhage International Trialists (SAHIT) repository who did not receive IT nicardipine." | 8.12 | Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis. ( Akbik, F; Ameli, P; Asbury, W; Barrow, DL; Cawley, CM; Danyluk, L; Feng, C; Garner, K; Jaja, BNR; Kolenda, J; Kraft, J; Macdonald, RL; Martin, KS; Mathew, S; Mei, Y; Moore, R; Pearce, D; Pimentel, C; Pujari, A; Sadan, O; Samuels, O; Taylor, A; Waddel, H, 2022) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 7.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "Vasospasm following subarachnoid hemorrhage (SAH) remains difficult to prevent despite extensive investigative efforts." | 5.34 | Nicardipine prolonged-release implants for preventing cerebral vasospasm after subarachnoid hemorrhage: effect and outcome in the first 100 patients. ( Hori, T; Kasuya, H; Krischek, B; Onda, H, 2007) |
| "A study of medical complications observed in the placebo limb of a large, randomized, controlled trial of the calcium antagonist, nicardipine, after subarachnoid hemorrhage." | 5.08 | Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study. ( Germanson, T; Haley, EC; Kassell, NF; Kongable, G; Solenski, NJ; Torner, JC; Truskowski, L, 1995) |
| " Using a propensity-score model, this patient cohort was compared to patients in the Subarachnoid Hemorrhage International Trialists (SAHIT) repository who did not receive IT nicardipine." | 4.12 | Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis. ( Akbik, F; Ameli, P; Asbury, W; Barrow, DL; Cawley, CM; Danyluk, L; Feng, C; Garner, K; Jaja, BNR; Kolenda, J; Kraft, J; Macdonald, RL; Martin, KS; Mathew, S; Mei, Y; Moore, R; Pearce, D; Pimentel, C; Pujari, A; Sadan, O; Samuels, O; Taylor, A; Waddel, H, 2022) |
| "OBJECTIVE Intravenous nicardipine is commonly used for blood pressure reduction in patients with acute stroke." | 3.88 | Paradoxical cerebrovascular hemodynamic changes with nicardipine. ( Lahiri, S; Lyden, PD; Mayer, SA; Nezhad, M; Rinsky, B; Rosengart, A; Schlick, KH, 2018) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 3.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "Nicardipine is a dihydropyridine-type Ca(2+) channel blocker with a powerful antihypertensive activity and a unique cerebrovascular profile." | 2.49 | Nicardipine in the treatment of aneurysmal subarachnoid haemorrhage: a meta-analysis of published data. ( Feng, ZM; Huang, RQ; Jiang, FG; Wang, TY, 2013) |
| "Postoperative meningitis is a serious complication occurring after neurosurgical interventions." | 1.42 | Risk factors for meningitis after craniotomy in patients with subarachnoid hemorrhage due to anterior circulation aneurysms rupture. ( Endo, H; Fujimura, M; Inoue, T; Niizuma, K; Sakata, H; Sato, K; Shimizu, H; Tominaga, T, 2015) |
| "We report a case of subarachnoid hemorrhage from a thrombosed ruptured aneurysm which was undetected on digital subtraction angiography but was visualized with cone beam volume CT." | 1.39 | The utility of cone beam volume CT in the evaluation of thrombosed intracranial aneurysms in subarachnoid hemorrhage. ( Hannawi, Y; Murthy, SB; Rao, CP; Shah, S, 2013) |
| "Vasospasm following subarachnoid hemorrhage (SAH) remains difficult to prevent despite extensive investigative efforts." | 1.34 | Nicardipine prolonged-release implants for preventing cerebral vasospasm after subarachnoid hemorrhage: effect and outcome in the first 100 patients. ( Hori, T; Kasuya, H; Krischek, B; Onda, H, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Sadan, O | 1 |
| Waddel, H | 1 |
| Moore, R | 1 |
| Feng, C | 1 |
| Mei, Y | 1 |
| Pearce, D | 1 |
| Kraft, J | 1 |
| Pimentel, C | 1 |
| Mathew, S | 1 |
| Akbik, F | 1 |
| Ameli, P | 1 |
| Taylor, A | 1 |
| Danyluk, L | 1 |
| Martin, KS | 1 |
| Garner, K | 1 |
| Kolenda, J | 1 |
| Pujari, A | 1 |
| Asbury, W | 1 |
| Jaja, BNR | 1 |
| Macdonald, RL | 1 |
| Cawley, CM | 1 |
| Barrow, DL | 1 |
| Samuels, O | 1 |
| Lahiri, S | 1 |
| Nezhad, M | 1 |
| Schlick, KH | 1 |
| Rinsky, B | 1 |
| Rosengart, A | 1 |
| Mayer, SA | 1 |
| Lyden, PD | 1 |
| Inoue, T | 1 |
| Shimizu, H | 1 |
| Fujimura, M | 1 |
| Sato, K | 1 |
| Endo, H | 1 |
| Niizuma, K | 1 |
| Sakata, H | 1 |
| Tominaga, T | 1 |
| Huang, RQ | 1 |
| Jiang, FG | 1 |
| Feng, ZM | 1 |
| Wang, TY | 1 |
| Shah, S | 1 |
| Murthy, SB | 1 |
| Hannawi, Y | 1 |
| Rao, CP | 1 |
| Krischek, B | 1 |
| Kasuya, H | 1 |
| Onda, H | 1 |
| Hori, T | 1 |
| Shibuya, M | 1 |
| Suzuki, Y | 1 |
| Enomoto, H | 1 |
| Okada, T | 1 |
| Ogura, K | 1 |
| Sugita, K | 1 |
| Solenski, NJ | 1 |
| Haley, EC | 1 |
| Kassell, NF | 1 |
| Kongable, G | 1 |
| Germanson, T | 1 |
| Truskowski, L | 1 |
| Torner, JC | 1 |
| Kitano, H | 1 |
| Matsuda, M | 1 |
| Weir, B | 1 |
| MacDonald, L | 1 |
| Saito, I | 1 |
| Yoshimura, S | 1 |
| Tsukahara, T | 2 |
| Hashimoto, N | 1 |
| Kazekawa, K | 2 |
| Kobayashi, A | 1 |
| Kaku, Y | 1 |
| Yonekawa, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731] | Phase 2 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nicardipine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Nicardipine in the treatment of aneurysmal subarachnoid haemorrhage: a meta-analysis of published data.
Topics: Aneurysm, Ruptured; Calcium Channel Blockers; Humans; Nicardipine; Subarachnoid Hemorrhage; Treatmen | 2013 |
Cerebral vasospasm.
Topics: Aneurysm, Ruptured; Blood Pressure; Blood Volume; Brain Ischemia; Catheterization; Cerebral Infarcti | 1993 |
2 trials available for nicardipine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Effects of prophylactic intrathecal administrations of nicardipine on vasospasm in patients with severe aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Basilar Artery; Cerebral Angiography; Female; Humans; Injections, S | 1994 |
Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Cause of Death; Critical Care; Double-Blind Meth | 1995 |
9 other studies available for nicardipine and Aneurysm, Ruptured
| Article | Year |
|---|---|
Does intrathecal nicardipine for cerebral vasospasm following subarachnoid hemorrhage correlate with reduced delayed cerebral ischemia? A retrospective propensity score-based analysis.
Topics: Adult; Age Factors; Aged; Aneurysm, Ruptured; Aortic Rupture; Calcium Channel Blockers; Critical Car | 2022 |
Paradoxical cerebrovascular hemodynamic changes with nicardipine.
Topics: Administration, Intravenous; Adult; Aged; Aneurysm, Ruptured; Blood Flow Velocity; Calcium Channel B | 2018 |
Risk factors for meningitis after craniotomy in patients with subarachnoid hemorrhage due to anterior circulation aneurysms rupture.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angiography, Digital Subtraction; Antibiotic Pro | 2015 |
The utility of cone beam volume CT in the evaluation of thrombosed intracranial aneurysms in subarachnoid hemorrhage.
Topics: Activities of Daily Living; Aneurysm, Ruptured; Angiography, Digital Subtraction; Angioplasty, Ballo | 2013 |
Nicardipine prolonged-release implants for preventing cerebral vasospasm after subarachnoid hemorrhage: effect and outcome in the first 100 patients.
Topics: Aged; Aneurysm, Ruptured; Drug Implants; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; M | 2007 |
[Effect of high dose nicardipine in patients with ruptured cerebral aneurysm].
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; | 1993 |
[Controversies in the surgical treatment of subarachnoid hemorrhage with special reference to the prognosis of patients].
Topics: Adult; Age Factors; Aged; Aneurysm, Ruptured; Female; Humans; Intracranial Aneurysm; Male; Middle Ag | 1993 |
Intra-arterial infusion of papaverine combined with intravenous administration of high-dose nicardipine for cerebral vasospasm.
Topics: Adult; Aged; Aneurysm, Ruptured; Calcium Channel Blockers; Cerebral Angiography; Dose-Response Relat | 1995 |
Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty, Balloon; Female; Humans; Infusions, | 1992 |