nicardipine has been researched along with Anesthesia in 27 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of diltiazem intoxication resulting in repeated asystole after the induction of anesthesia." | 7.78 | [Suspected diltiazem intoxication resulting in repeated asystole after the induction of anesthesia]. ( Hara, T; Harioka, T; Ishiyama, T; Kimura, Y; Matsukawa, T; Nakasato, A; Okamura, M, 2012) |
| "Cardiovascular effects of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine), a calcium channel blocker, were investigated in anesthetized normal dogs and dogs with acute heart failure (AHF), and compared with those of nitroglycerin (NTG)." | 7.70 | Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 1: Hemodynamic effects in normal dogs and dogs with acute heart failure. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998) |
| "The effect of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine) on myocardial metabolism was investigated in an experimental model of ischemic acute heart failure (AHF) induced by coronary ligation in anesthetized dogs." | 7.70 | Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 7.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| "Nicardipine has been used to control blood pressure intraoperatively in response to tracheal intubation and in the postoperative period." | 6.39 | Nicardipine: applications in anesthesia practice. ( Tobias, JD, 1995) |
| "Nicardipine hydrochloride is a short-acting dihydropyridine calcium antagonist with a unique configuration and characteristics that make it attractive for intraoperative and postoperative use." | 6.38 | The role of nicardipine during anesthesia and surgery. ( Kaplan, JA, 1989) |
| "Diltiazem and nicardipine, when injected as a mixture during anesthesia, reduce blood pressure in an additive manner without changing heart rate." | 5.10 | Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation. ( Tsutsui, T, 2002) |
| "We present a case of diltiazem intoxication resulting in repeated asystole after the induction of anesthesia." | 3.78 | [Suspected diltiazem intoxication resulting in repeated asystole after the induction of anesthesia]. ( Hara, T; Harioka, T; Ishiyama, T; Kimura, Y; Matsukawa, T; Nakasato, A; Okamura, M, 2012) |
| "Cardiovascular effects of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine), a calcium channel blocker, were investigated in anesthetized normal dogs and dogs with acute heart failure (AHF), and compared with those of nitroglycerin (NTG)." | 3.70 | Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 1: Hemodynamic effects in normal dogs and dogs with acute heart failure. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998) |
| "The effect of nicardipine hydrochloride (NIC, CAS 54527-84-3, Perdipine) on myocardial metabolism was investigated in an experimental model of ischemic acute heart failure (AHF) induced by coronary ligation in anesthetized dogs." | 3.70 | Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism. ( Asano, M; Maehara, J; Momose, K; Saitoh, C; Saitoh, M; Sato, S; Taguchi, K; Tanaka, H; Usuda, S, 1998) |
| " Blood pressure was maintained by bolus administration of nicardipine for the removal of pheochromocytoma." | 3.70 | Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report. ( Hanzawa, K; Motoyama, Y; Shiraishi, M, 1999) |
| "Hypokalemia was not clearly recognized preoperatively but became obvious within 3 h of general anesthesia with epidural blockade." | 1.37 | Ectopic ACTH syndrome revealed as severe hypokalemia and persistent hypertension during the perioperative period: a case report. ( Fukuda, K; Hirota, K; Kishimoto, S; Segawa, H, 2011) |
| "Cerebral vasospasm after subarachnoid hemorrhage can decrease cerebral blood flow with the potential for stroke." | 1.34 | Anesthetic considerations of selective intra-arterial nicardipine injection for intracranial vasospasm: a case series. ( Avitsian, R; Fiorella, D; Mascha, E; Soliman, MM, 2007) |
| "Nicardipine was used as hypotensive drug." | 1.29 | [Application of the concept of fuzzy logistic controller for treatment of hypertension during anesthesia]. ( Hiraoka, I; Kaieda, R; Murakawa, T; Nakakimura, K; Oshita, S; Tamura, H, 1993) |
| " Tolerance of the antihypertensive effect of TC-81 in daily dosing for 2 weeks and the rebound phenomena after discontinuance of the treatment were not observed in RHD." | 1.28 | Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs. ( Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Sunakawa, K; Takeshita, T; Tanabe, H, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 14 (51.85) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 4 (14.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hippard, HK | 1 |
| Watcha, M | 1 |
| Stocco, AJ | 1 |
| Curry, D | 1 |
| Chiba, T | 1 |
| Yamanaka, M | 1 |
| Takagi, S | 1 |
| Shimizu, K | 1 |
| Takahashi, M | 1 |
| Shirai, K | 1 |
| Takahara, A | 1 |
| Fukagawa, H | 1 |
| Hashiguchi, M | 1 |
| Ayabe, Y | 1 |
| Ando, T | 1 |
| Nakamura, K | 1 |
| Kishimoto, S | 1 |
| Hirota, K | 1 |
| Segawa, H | 1 |
| Fukuda, K | 1 |
| Kimura, Y | 1 |
| Okamura, M | 1 |
| Harioka, T | 1 |
| Hara, T | 1 |
| Nakasato, A | 1 |
| Ishiyama, T | 1 |
| Matsukawa, T | 1 |
| Avitsian, R | 1 |
| Fiorella, D | 1 |
| Soliman, MM | 1 |
| Mascha, E | 1 |
| Wei, JY | 1 |
| Su, ML | 1 |
| Duan, MJ | 1 |
| Chen, YH | 1 |
| Liu, XM | 1 |
| Watanabe, H | 1 |
| Furukawa, Y | 1 |
| Iwatsuki, K | 1 |
| Chiba, S | 1 |
| Wada, K | 1 |
| Nakamura, S | 1 |
| Morishita, S | 1 |
| Kanda, M | 1 |
| Matsui, H | 1 |
| Fukata, F | 1 |
| Shirahase, H | 1 |
| Kawabata, K | 1 |
| Sumikawa, K | 1 |
| Kamibayashi, T | 1 |
| Kita, T | 1 |
| Takada, K | 1 |
| Mashimo, T | 1 |
| Yoshiya, I | 1 |
| Oshita, S | 1 |
| Nakakimura, K | 1 |
| Kaieda, R | 1 |
| Murakawa, T | 1 |
| Tamura, H | 1 |
| Hiraoka, I | 1 |
| Hayashi, K | 2 |
| Uchida, T | 1 |
| Kido, H | 1 |
| Shinyama, H | 1 |
| Watanabe, M | 1 |
| Tobias, JD | 1 |
| Song, D | 1 |
| Singh, H | 1 |
| White, PF | 1 |
| Gadhiali, M | 1 |
| Griffin, JD | 1 |
| Klein, KW | 1 |
| Saitoh, C | 2 |
| Momose, K | 2 |
| Tanaka, H | 2 |
| Sato, S | 2 |
| Taguchi, K | 2 |
| Saitoh, M | 2 |
| Maehara, J | 2 |
| Asano, M | 2 |
| Usuda, S | 2 |
| Shiraishi, M | 1 |
| Hanzawa, K | 1 |
| Motoyama, Y | 1 |
| Kimura, T | 1 |
| Ito, M | 1 |
| Komatsu, T | 1 |
| Nishiwaki, K | 1 |
| Shimada, Y | 1 |
| Yamasaki, T | 1 |
| Ohmagari, M | 1 |
| Tamai, I | 1 |
| Matsumura, Y | 1 |
| Tsutsui, T | 1 |
| Yokoyama, T | 1 |
| Masuda, Y | 1 |
| Sakai, T | 1 |
| Tanaka, S | 1 |
| Tomita, K | 1 |
| Iwamoto, T | 1 |
| Morita, T | 1 |
| Sukamoto, T | 1 |
| Ito, K | 1 |
| Hojo, M | 1 |
| Teramoto, N | 1 |
| Hata, H | 1 |
| Katayama, O | 1 |
| Tatsumi, H | 1 |
| Shibata, S | 1 |
| Okamiya, Y | 1 |
| Kishimoto, T | 1 |
| Sunakawa, K | 1 |
| Aoki, K | 1 |
| Tanabe, H | 1 |
| Takeshita, T | 1 |
| Naruchi, T | 1 |
| Kaplan, JA | 1 |
| Nagaoka, A | 1 |
| Shibota, M | 1 |
| Hamajo, K | 1 |
| Allely, MC | 1 |
| Alps, BJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429] | Phase 4 | 144 participants (Anticipated) | Interventional | 2019-04-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for nicardipine and Anesthesia
| Article | Year |
|---|---|
Nicardipine: applications in anesthesia practice.
Topics: Anesthesia; Anesthetics; Calcium Channel Blockers; Drug Interactions; Humans; Nicardipine | 1995 |
The role of nicardipine during anesthesia and surgery.
Topics: Anesthesia; Humans; Intraoperative Period; Nicardipine; Surgical Procedures, Operative | 1989 |
4 trials available for nicardipine and Anesthesia
| Article | Year |
|---|---|
Decrease in vecuronium infusion dose requirements by nicardipine in humans.
Topics: Adult; Anesthesia; Dose-Response Relationship, Drug; Drug Interactions; Ear; Female; Humans; Infusio | 1994 |
Optimal dose of nicardipine for maintenance of hemodynamic stability after tracheal intubation and skin incision.
Topics: Adult; Anesthesia; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dermatologic S | 1997 |
Heart rate and blood pressure power spectral analysis during calcium channel blocker induced hypotension.
Topics: Adult; Anesthesia; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Hip; Hum | 1999 |
Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation.
Topics: Aged; Anesthesia; Anesthesia Recovery Period; Antihypertensive Agents; Blood Pressure; Diltiazem; Dr | 2002 |
21 other studies available for nicardipine and Anesthesia
| Article | Year |
|---|---|
Preservation of microelectrode recordings with non-GABAergic drugs during deep brain stimulator placement in children.
Topics: Adolescent; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Antihypertensive Agents; C | 2014 |
Cardio-ankle vascular index (CAVI) differentiates pharmacological properties of vasodilators nicardipine and nitroglycerin in anesthetized rabbits.
Topics: Anesthesia; Animals; Ankle Brachial Index; Arteriosclerosis; Blood Pressure; Brachial Artery; Dose-R | 2015 |
[Anesthetic management of undiagnosed pheochromocytoma: a case report].
Topics: Adrenal Gland Neoplasms; Anesthesia; Antihypertensive Agents; Humans; Hypertension; Intraoperative C | 2008 |
Ectopic ACTH syndrome revealed as severe hypokalemia and persistent hypertension during the perioperative period: a case report.
Topics: ACTH Syndrome, Ectopic; Adjuvants, Anesthesia; Anesthesia; Anesthetics, Intravenous; Blood Gas Analy | 2011 |
[Suspected diltiazem intoxication resulting in repeated asystole after the induction of anesthesia].
Topics: Adult; Anesthesia; Diltiazem; Drug Interactions; Embolization, Therapeutic; Heart Arrest; Humans; In | 2012 |
Anesthetic considerations of selective intra-arterial nicardipine injection for intracranial vasospasm: a case series.
Topics: Adult; Aged; Anesthesia; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Injec | 2007 |
[Effects of nicardipine on vertebral vascular resistance in anesthetized dogs and spontaneous activity in mice].
Topics: Anesthesia; Animals; Dogs; Female; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Pyridines; V | 1983 |
Effects of nicardipine on the cross-perfused canine atrium.
Topics: Anesthesia; Animals; Chlorides; Dogs; Female; Heart; Heart Rate; Male; Manganese; Manganese Compound | 1981 |
Antihypertensive effect of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride in rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid | 1994 |
[Application of the concept of fuzzy logistic controller for treatment of hypertension during anesthesia].
Topics: Anesthesia; Female; Fuzzy Logic; Humans; Hypertension; Infusion Pumps; Male; Middle Aged; Nicardipin | 1993 |
Effects of AE0047 on renal haemodynamics and function in anaesthetized dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Dogs; Hemodynamics; Infus | 1993 |
Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 1: Hemodynamic effects in normal dogs and dogs with acute heart failure.
Topics: Acute Disease; Adrenergic beta-Agonists; Anesthesia; Angiotensin II; Animals; Blood Pressure; Calciu | 1998 |
Pharmacological profile of nicardipine hydrochloride in anesthetized dogs with acute heart failure. Part 2: Effect on myocardial metabolism.
Topics: Acute Disease; Anesthesia; Animals; Calcium Channel Blockers; Dogs; Female; Heart Failure; Hemodynam | 1998 |
Anesthetic management for pheochromocytoma resection using spinal cord stimulation and intravenous nicardipine--a case report.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Blood Pressure; Calcium Channel Blockers; Female; Humans | 1999 |
Inhibitory effects of AE0047, a new dihydropyridine Ca(2+) channel blocker, on renal nerve stimulation-induced renal actions in anesthetized dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Electric Stimulation; Female; | 2000 |
Effects of NZ-105, a new calcium antagonist, on renal function in anesthetized spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid | 1992 |
Effects of KB-2796, a new diphenylpiperazine calcium antagonist, on renal hemodynamics and urine formation in anesthetized dogs.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Diuresis; Dogs; Female; Kidney; Male; Nicardipine; Pi | 1992 |
Cardiovascular effects of the new generation calcium antagonist 3-pyridine carboxylic acid 5-[(cyclopropylamino)carbonyl]-1,4-dihydro-2,6-dimethyl-4-(2-nitropheny l) octyl ester.
Topics: Anesthesia; Animals; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; Female; | 1992 |
Antihypertensive effect of the new dihydropyridine calcium antagonist (+-)-3-(benzylmethylamino)-2,2-dimethylpropyl methyl 4-(2-fluoro-5-nitrophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica rbo xylate hydrochloride in dogs.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyrid | 1992 |
Effects of a new dihydropyridine derivative, CV-4093.2HCl, on renal hemodynamics in spontaneously hypertensive rats.
Topics: Anesthesia; Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Hea | 1989 |
The effects of the novel anti-anginal compound RS 43285 on myocardial conduction in the anaesthetized dog.
Topics: Acetanilides; Anesthesia; Angina Pectoris; Animals; Atrioventricular Node; Dogs; Electrocardiography | 1988 |