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nicardipine and Albuminuria

nicardipine has been researched along with Albuminuria in 8 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Renal hemodynamics was investigated in 25 patients."6.68Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes. ( Andriani, A; Bertocchi, F; Bonfantino, MV; Cavallo, A; De Cesaris, R; Lamontanara, G; Ranieri, G, 1996)
"Seven of eight hypertensive Type 2 (non-insulin-dependent) diabetic patients with microalbuminuria completed a randomised crossover trial to compare the renal effects of angiotensin converting enzyme inhibitor (enalapril) and calcium antagonist (nicardipine)."5.06Comparison of the renal effects of angiotensin converting enzyme inhibitor and calcium antagonist in hypertensive type 2 (non-insulin-dependent) diabetic patients with microalbuminuria: a randomised controlled trial. ( Baba, T; Murabayashi, S; Takebe, K, 1989)
"We studied the renal effects of nicardipine, a calcium entry blocker, in eight patients with essential hypertension (group A, WHO I or II), six hypertensive type II diabetics with mild-to-moderate nephropathy (group B, urinary albumin 200-789 mg/day), and six hypertensive type II diabetics with severe or advanced nephropathy (group C, urinary albumin 1,596-4,300 mg/day)."5.06Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy. ( Aoyagi, K; Baba, T; Ido, Y; Ishizaki, T; Murabayashi, S; Takebe, K, 1986)
"The renal effects of oral maintenance doses of nicardipine 60-120 mg/day have been studied in 18 hypertensive patients with Type 2 (non-insulin-dependent) diabetes mellitus: 6 with normoalbuminuria (urinary albumin excretion rate, AER less than 20 micrograms."3.68Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy. ( Baba, T; Murabayashi, S; Takebe, K; Tomiyama, T, 1990)
"Renal hemodynamics was investigated in 25 patients."2.68Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes. ( Andriani, A; Bertocchi, F; Bonfantino, MV; Cavallo, A; De Cesaris, R; Lamontanara, G; Ranieri, G, 1996)
"Treatment with nicardipine significantly reduced blood pressure and albuminuria and increased urinary sodium excretion."1.29Protective effect of nicardipine treatment on renal microanatomical changes in spontaneously hypertensive rats. ( Abbate, F; Amenta, F; Ciriaco, E; Ferrante, F; Polidori, C, 1994)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's5 (62.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferrante, F1
Abbate, F1
Ciriaco, E1
Polidori, C1
Amenta, F2
Bigazzi, R2
Bianchi, S2
Baldari, D1
Sgherri, G1
Baldari, G2
Campese, VM2
De Cesaris, R1
Ranieri, G1
Andriani, A1
Lamontanara, G1
Cavallo, A1
Bonfantino, MV1
Bertocchi, F1
Sabbatini, M1
Leonardi, A1
Testa, R1
Vitaioli, L1
Baba, T3
Tomiyama, T1
Murabayashi, S3
Takebe, K3
Ishizaki, T1
Ido, Y1
Aoyagi, K1

Trials

5 trials available for nicardipine and Albuminuria

ArticleYear
Long-term effects of a converting enzyme inhibitor and a calcium channel blocker on urinary albumin excretion in patients with essential hypertension.
    American journal of hypertension, 1993, Volume: 6, Issue:2

    Topics: Albuminuria; Blood Pressure; Enalapril; Humans; Hypertension; Middle Aged; Morbidity; Nicardipine; P

1993
Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:4

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Benzazepines; Diabetes Mellitus, Type 1; Diabetes

1996
Long-term effects of enalapril and nicardipine on urinary albumin excretion in patients with chronic renal insufficiency: a 1-year follow-up.
    American journal of nephrology, 1991, Volume: 11, Issue:2

    Topics: Albuminuria; Enalapril; Female; Follow-Up Studies; Humans; Hypertension, Renal; Kidney Failure, Chro

1991
Comparison of the renal effects of angiotensin converting enzyme inhibitor and calcium antagonist in hypertensive type 2 (non-insulin-dependent) diabetic patients with microalbuminuria: a randomised controlled trial.
    Diabetologia, 1989, Volume: 32, Issue:1

    Topics: Aged; Albuminuria; Blood Pressure; Blood Proteins; Clinical Trials as Topic; Diabetes Mellitus, Type

1989
Renal effects of nicardipine, a calcium entry blocker, in hypertensive type II diabetic patients with nephropathy.
    Diabetes, 1986, Volume: 35, Issue:11

    Topics: Adult; Albuminuria; Clinical Trials as Topic; Diabetic Nephropathies; Female; Glomerular Filtration

1986

Other Studies

3 other studies available for nicardipine and Albuminuria

ArticleYear
Protective effect of nicardipine treatment on renal microanatomical changes in spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:4

    Topics: Albuminuria; Animals; Hypertension; Hypertrophy; Kidney; Kidney Glomerulus; Male; Microscopy, Electr

1994
Effect of calcium antagonists on glomerular arterioles in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:3

    Topics: Albuminuria; Animals; Arterioles; Calcium; Calcium Channel Blockers; Dihydropyridines; Hydralazine;

2000
Renal effects of nicardipine, a calcium antagonist, in hypertensive type 2 (non-insulin-dependent) diabetic patients with and without nephropathy.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:5

    Topics: Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate;

1990