nicardipine has been researched along with Absence Seizure in 15 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of a single and multiple doses of ginkgolide A, B, C, and bilobalide, active components of Ginkgo biloba extract (EGb 761), on absence seizures were investigated in male WAG/Rij rats, a genetic animal model of absence epilepsy." | 8.31 | Investigating the mechanism of action of ginkgolides and bilobalide on absence seizures in male WAG/Rij rats. ( Akca, M; Gedikli, Ö; Yildirim, M, 2023) |
| " The aim of this study was to investigate the effects of the calcium channel blockers, nimodipine, nicardipine and amlodipine, on the brain free fatty acid (FFA) level in rats with chemically-induced seizures." | 7.70 | The influence of nimodipine, nicardipine and amlodipine on the brain free fatty acid level in rats with penicillin-induced seizures. ( Eraković, V; Kriz, J; Simonić, A; Varljen, J; Zupan, G, 1999) |
| "The effects of a single and multiple doses of ginkgolide A, B, C, and bilobalide, active components of Ginkgo biloba extract (EGb 761), on absence seizures were investigated in male WAG/Rij rats, a genetic animal model of absence epilepsy." | 4.31 | Investigating the mechanism of action of ginkgolides and bilobalide on absence seizures in male WAG/Rij rats. ( Akca, M; Gedikli, Ö; Yildirim, M, 2023) |
| " The aim of this study was to investigate the effects of the calcium channel blockers, nimodipine, nicardipine and amlodipine, on the brain free fatty acid (FFA) level in rats with chemically-induced seizures." | 3.70 | The influence of nimodipine, nicardipine and amlodipine on the brain free fatty acid level in rats with penicillin-induced seizures. ( Eraković, V; Kriz, J; Simonić, A; Varljen, J; Zupan, G, 1999) |
| "Among three calcium channel inhibitors, only nicardipine (10-40 mg/kg) significantly inhibited clonic seizures induced by pentylenetetrazol administered at its CD97 (convulsive dose 97%) of 81 mg/kg, subcutaneously." | 3.69 | Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice. ( Brudniak, T; Czuczwar, SJ; Gasior, M; Kamiński, R; Kleinrok, Z, 1996) |
| " Nicardipine remarkably inhibited epileptic seizures induced by combined treatment with enoxacin (p." | 3.69 | Epileptogenic activity induced by combined treatment with antiinflammatory drugs and enoxacin and its inhibition by a calcium antagonist, nicardipine. ( Kamei, C; Kitazumi, K; Ohishi, H; Okumura, Y; Sugimoto, Y, 1996) |
| " Nicardipine in a dose of 1 to 2 mg/kg/day, added to conventional anticonvulsant drugs provided effective supplementary control of seizures, of paroxysmal EEG discharges, and of language and behavioural disturbances, even several years after the onset of the disorder and in patients whose response to other medications, including steroids, had been poor." | 3.68 | Is cerebral arteritis the cause of the Landau-Kleffner syndrome? Four cases in childhood with angiographic study. ( López Martín, V; Martínez Bermejo, A; Pascual-Castroviejo, I; Pérez Higueras, A, 1992) |
| "We present a case of neurogenic stunned myocardium, discovered intraoperatively after anesthetic induction, in a patient who presented to our operating room with a recent intraparenchymal hemorrhage." | 1.43 | Prolonged Cardiac Dysfunction After Intraparenchymal Hemorrhage and Neurogenic Stunned Myocardium. ( Krishnamoorthy, V; Sharma, D; Vavilala, MS; Wilson, T, 2016) |
| "We diagnosed postpartum eclampsia with posterior reversible encephalopathy syndrome (PRES) in a 35-year-old woman who began experiencing headaches after delivery." | 1.42 | Postpartum vertebral artery dissection with posterior reversible encephalopathy syndrome. ( Akita, H; Hiraoka, E; Kanazawa, K; Nishimura, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gedikli, Ö | 1 |
| Akca, M | 1 |
| Yildirim, M | 1 |
| Nishimura, M | 1 |
| Hiraoka, E | 1 |
| Kanazawa, K | 1 |
| Akita, H | 1 |
| Krishnamoorthy, V | 1 |
| Wilson, T | 1 |
| Sharma, D | 1 |
| Vavilala, MS | 1 |
| Awaji, K | 1 |
| Inokuchi, R | 1 |
| Maehara, H | 1 |
| Yamaguchi, Y | 1 |
| Kira, K | 1 |
| Doi, K | 1 |
| Morimura, N | 1 |
| Fletcher, JJ | 1 |
| Kramer, AH | 1 |
| Bleck, TP | 1 |
| Solenski, NJ | 1 |
| Oda, Y | 1 |
| Funao, T | 1 |
| Tanaka, K | 1 |
| Asada, A | 1 |
| Zhang, Y | 1 |
| White, PF | 2 |
| Thornton, L | 1 |
| Perdue, L | 1 |
| Downing, M | 1 |
| Gasior, M | 2 |
| Kamiński, R | 1 |
| Brudniak, T | 1 |
| Kleinrok, Z | 2 |
| Czuczwar, SJ | 2 |
| Kamei, C | 1 |
| Sugimoto, Y | 1 |
| Ohishi, H | 1 |
| Okumura, Y | 1 |
| Kitazumi, K | 1 |
| Borowicz, K | 1 |
| Starownik, R | 1 |
| Avramov, MN | 1 |
| Stool, LA | 1 |
| Husain, MM | 1 |
| Zupan, G | 1 |
| Eraković, V | 1 |
| Simonić, A | 1 |
| Kriz, J | 1 |
| Varljen, J | 1 |
| Hassan, H | 1 |
| Grecksch, G | 1 |
| Rüthrich, H | 1 |
| Krug, M | 1 |
| Ikegaya, Y | 1 |
| Nishiyama, N | 1 |
| Matsuki, N | 1 |
| Pascual-Castroviejo, I | 1 |
| López Martín, V | 1 |
| Martínez Bermejo, A | 1 |
| Pérez Higueras, A | 1 |
2 trials available for nicardipine and Absence Seizure
| Article | Year |
|---|---|
The use of nicardipine for electroconvulsive therapy: a dose-ranging study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channe | 2005 |
Effects of nicardipine and labetalol on the acute hemodynamic response to electroconvulsive therapy.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Antihypertensive Agents; Blood Pressure; C | 1998 |
13 other studies available for nicardipine and Absence Seizure
| Article | Year |
|---|---|
Investigating the mechanism of action of ginkgolides and bilobalide on absence seizures in male WAG/Rij rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bilobalides; Disease Models, Animal; Dizocilpine Male | 2023 |
Postpartum vertebral artery dissection with posterior reversible encephalopathy syndrome.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Female; Headache Disorders, Primary; Humans; Magnes | 2015 |
Prolonged Cardiac Dysfunction After Intraparenchymal Hemorrhage and Neurogenic Stunned Myocardium.
Topics: Adult; Anesthesia, General; Cerebral Hemorrhage; Emergency Service, Hospital; Heart; Hemangioma, Cav | 2016 |
Woman with Hypertension and Seizure.
Topics: Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Female; Humans; Hypertension; Mag | 2017 |
Overlapping features of eclampsia and postpartum angiopathy.
Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipi | 2009 |
Vasodilation increases the threshold for bupivacaine-induced convulsions in rats.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Brain | 2004 |
Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Clonazepam; Drug Interactions; Ethosuximide; Flu | 1996 |
Epileptogenic activity induced by combined treatment with antiinflammatory drugs and enoxacin and its inhibition by a calcium antagonist, nicardipine.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 1996 |
Anticonvulsant and adverse effects of MK-801, LY 235959, and GYKI 52466 in combination with Ca2+ channel inhibitors in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Benzodiazepines; Calcium Channel | 1997 |
The influence of nimodipine, nicardipine and amlodipine on the brain free fatty acid level in rats with penicillin-induced seizures.
Topics: Amlodipine; Animals; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Fatty Acid | 1999 |
Effects of nicardipine, an antagonist of L-type voltage-dependent calcium channels, on kindling development, kindling-induced learning deficits and hippocampal potentiation phenomena.
Topics: Animals; Avoidance Learning; Calcium Channel Blockers; Calcium Channels, L-Type; Convulsants; Dentat | 1999 |
L-type Ca(2+) channel blocker inhibits mossy fiber sprouting and cognitive deficits following pilocarpine seizures in immature mice.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cogn | 2000 |
Is cerebral arteritis the cause of the Landau-Kleffner syndrome? Four cases in childhood with angiographic study.
Topics: Adolescent; Aphasia; Arteritis; Cerebral Angiography; Cerebral Arteries; Child; Electroencephalograp | 1992 |