Page last updated: 2024-10-19

niacinamide and Wilms Tumor

niacinamide has been researched along with Wilms Tumor in 2 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.

Research Excerpts

ExcerptRelevanceReference
"Sorafenib, 200 mg/m(2) /dose, was administered every 12 hr continuously for 28 day cycles using a two-stage design in two primary strata (rhabdomyosarcoma and Wilms tumor) and two secondary strata (HCC and PTC)."5.20Phase 2 trial of sorafenib in children and young adults with refractory solid tumors: A report from the Children's Oncology Group. ( Blaney, SM; Fox, E; Jayaprakash, N; Kim, A; Krailo, M; Weigel, B; Widemann, BC, 2015)
" In a study evaluating the combination of sorafenib, bevacizumab, and low-dose cyclophosphamide in children with solid tumors, an unexpectedly high incidence of pneumothorax was observed."3.81Pneumothorax as a complication of combination antiangiogenic therapy in children and young adults with refractory/recurrent solid tumors. ( Davidoff, AM; Interiano, RB; McCarville, MB; Navid, F; Sandoval, J; Wu, J, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Interiano, RB1
McCarville, MB1
Wu, J1
Davidoff, AM1
Sandoval, J1
Navid, F1
Kim, A1
Widemann, BC1
Krailo, M1
Jayaprakash, N1
Fox, E1
Weigel, B1
Blaney, SM1

Trials

1 trial available for niacinamide and Wilms Tumor

ArticleYear
Phase 2 trial of sorafenib in children and young adults with refractory solid tumors: A report from the Children's Oncology Group.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:9

    Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Agents; Child; Child, Preschool; Female; Humans;

2015

Other Studies

1 other study available for niacinamide and Wilms Tumor

ArticleYear
Pneumothorax as a complication of combination antiangiogenic therapy in children and young adults with refractory/recurrent solid tumors.
    Journal of pediatric surgery, 2015, Volume: 50, Issue:9

    Topics: Adolescent; Adult; Angiogenesis Inhibitors; Bevacizumab; Bone Neoplasms; Child; Child, Preschool; Fe

2015