niacinamide has been researched along with Wallerian Degeneration in 4 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Wallerian Degeneration: Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Important insight into the mechanisms of axon degeneration arose from findings that the degeneration of transected axons is delayed in Wallerian degeneration slow (Wlds) mice with the overexpression of a fusion protein with the nicotinamide adenine dinucleotide (NAD) synthetic enzyme, nicotinamide mononucleotide adenylyltransferase (Nmnat1)." | 3.73 | A local mechanism mediates NAD-dependent protection of axon degeneration. ( Chen, Y; Gu, W; He, Z; Lin, E; McBurney, MW; Wang, J; Zhai, Q, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loring, HS | 1 |
| Parelkar, SS | 1 |
| Mondal, S | 1 |
| Thompson, PR | 1 |
| Meyer zu Horste, G | 1 |
| Miesbach, TA | 1 |
| Muller, JI | 1 |
| Fledrich, R | 1 |
| Stassart, RM | 1 |
| Kieseier, BC | 1 |
| Coleman, MP | 1 |
| Sereda, MW | 1 |
| Ocampo, A | 1 |
| Liu, J | 1 |
| Barrientos, A | 1 |
| Wang, J | 1 |
| Zhai, Q | 1 |
| Chen, Y | 1 |
| Lin, E | 1 |
| Gu, W | 1 |
| McBurney, MW | 1 |
| He, Z | 1 |
4 other studies available for niacinamide and Wallerian Degeneration
| Article | Year |
|---|---|
Identification of the first noncompetitive SARM1 inhibitors.
Topics: Amino Acid Motifs; Amino Acid Sequence; Armadillo Domain Proteins; Axons; Berberine; Binding Sites; | 2020 |
The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration.
Topics: Animals; Axons; Charcot-Marie-Tooth Disease; Disease Models, Animal; Female; Nerve Tissue Proteins; | 2011 |
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins.
Topics: alpha-Synuclein; Gene Expression; Histone Deacetylases; Mitochondria; NAD; Niacinamide; Nicotinamide | 2013 |
A local mechanism mediates NAD-dependent protection of axon degeneration.
Topics: Adenosine Triphosphate; Animals; Axons; Cells, Cultured; Mice; NAD; Nerve Tissue Proteins; Niacinami | 2005 |