Page last updated: 2024-10-19

niacinamide and Vomiting

niacinamide has been researched along with Vomiting in 13 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"This study was performed to identify clinical predictors for better survival in patients with advanced hepatocellular carcinoma (HCC) under sorafenib treatment."7.79Diarrhea is a positive outcome predictor for sorafenib treatment of advanced hepatocellular carcinoma. ( Ganten, TM; Gotthardt, D; Jaeger, D; Koehler, C; Koschny, R; Stremmel, W, 2013)
"To study the efficacy of tetracycline (or doxycycline) and nicotinamide in the treatment of less extensive bullous pemphigoid."7.70Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore. ( Goon, AT; Khoo, LS; Tan, SH; Tan, T, 2000)
"This study was performed to identify clinical predictors for better survival in patients with advanced hepatocellular carcinoma (HCC) under sorafenib treatment."3.79Diarrhea is a positive outcome predictor for sorafenib treatment of advanced hepatocellular carcinoma. ( Ganten, TM; Gotthardt, D; Jaeger, D; Koehler, C; Koschny, R; Stremmel, W, 2013)
"Pellagra is a nutritional disease caused by the deficiency of niacin."3.79Pellagra revealing a congenital duodenal diaphragm in an adult. ( Ahmed, S; Farah, J; Haykel, B; Houcine, M; Khouloud, B; Yacine, BS; Zoubeir, BS, 2013)
"To study the efficacy of tetracycline (or doxycycline) and nicotinamide in the treatment of less extensive bullous pemphigoid."3.70Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore. ( Goon, AT; Khoo, LS; Tan, SH; Tan, T, 2000)
" Frequently occurring motesanib-related adverse events included diarrhea (n = 19), nausea (n = 18), vomiting (n = 13), and fatigue (n = 12), which were mostly of worst grade < 3."2.76Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study. ( Adewoye, AH; Desai, J; Johnson, J; Kotasek, D; McCoy, S; Price, T; Siu, LL; Sun, YN; Tebbutt, N; Welch, S, 2011)
"Full pharmacokinetic profiles of nicotinamide concentrations in plasma were analyzed repeatedly in 15 patients to determine the inter- and intra-patient variability in peak plasma concentrations and the optimum times for administering nicotinamide as a radiosensitizer."2.69Pharmacokinetics of nicotinamide in cancer patients treated with accelerated radiotherapy: the experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer. ( Bernier, J; Bieri, S; Bolla, M; Denekamp, J; Dennis, MF; Hagen, F; Kocagöncü, O; Rojas, A; Stratford, MR, 1998)
"Diarrhea was the most common GI event."2.50Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials. ( Berardi, R; Burattini, L; Cascinu, S; Conti, A; De Giorgi, U; Iacovelli, R; Muzzonigro, G; Pantano, F; Santini, D; Santoni, M, 2014)
" A next group of 87 patients received 60 mg/kg nicotinamide in combination with domperidone."1.31Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy. ( Bussink, J; Folkes, LK; Kaanders, JH; Stratford, MR; van der Kogel, AJ, 2002)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santoni, M1
Conti, A1
De Giorgi, U1
Iacovelli, R1
Pantano, F1
Burattini, L1
Muzzonigro, G1
Berardi, R1
Santini, D1
Cascinu, S1
De Savi, C1
Cox, RJ1
Warner, DJ1
Cook, AR1
Dickinson, MR1
McDonough, A1
Morrill, LC1
Parker, B1
Andrews, G1
Young, SS1
Gilmour, PS1
Riley, R1
Dearman, MS1
Kotasek, D1
Tebbutt, N1
Desai, J1
Welch, S1
Siu, LL1
McCoy, S1
Sun, YN1
Johnson, J1
Adewoye, AH1
Price, T1
Koschny, R1
Gotthardt, D1
Koehler, C1
Jaeger, D1
Stremmel, W1
Ganten, TM1
Khouloud, B1
Haykel, B1
Ahmed, S1
Houcine, M1
Yacine, BS1
Farah, J1
Zoubeir, BS1
Bussink, J1
Stratford, MR3
van der Kogel, AJ1
Folkes, LK1
Kaanders, JH1
Ruddock, MW2
Hirst, DG2
Saunders, MI1
Hoskin, PJ1
Pigott, K1
Powell, ME1
Goodchild, K1
Dische, S1
Denekamp, J2
Dennis, MF2
Rojas, AM1
Bernier, J1
Bieri, S1
Hagen, F1
Kocagöncü, O1
Bolla, M1
Rojas, A1
Burns, DM1
Murphy, LE1
O'Rourke, MG1
Goon, AT1
Tan, SH1
Khoo, LS1
Tan, T1
Burnouf, C1
Auclair, E1
Avenel, N1
Bertin, B1
Bigot, C1
Calvet, A1
Chan, K1
Durand, C1
Fasquelle, V1
Féru, F1
Gilbertsen, R1
Jacobelli, H1
Kebsi, A1
Lallier, E1
Maignel, J1
Martin, B1
Milano, S1
Ouagued, M1
Pascal, Y1
Pruniaux, MP1
Puaud, J1
Rocher, MN1
Terrasse, C1
Wrigglesworth, R1
Doherty, AM1
Grillo, G1
Luvarà, A1
Rovere, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 1b, Open-label, Dose-finding Study of AMG 706 in Combination With Gemcitabine and Erlotinib to Treat Subjects With Solid Tumors[NCT01235416]Phase 157 participants (Actual)Interventional2005-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for niacinamide and Vomiting

ArticleYear
Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials.
    International journal of cancer, 2014, Aug-15, Volume: 135, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Carcinoma, Renal Cell; Clinical Trials as Topic; Diarrhea;

2014

Trials

3 trials available for niacinamide and Vomiting

ArticleYear
Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study.
    BMC cancer, 2011, Jul-26, Volume: 11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cohort Studies; Deoxy

2011
Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: a feasibility study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 45, Issue:2

    Topics: Administration, Oral; Aerosols; Antiemetics; Carbon Dioxide; Disease-Free Survival; Dose Fractionati

1997
Pharmacokinetics of nicotinamide in cancer patients treated with accelerated radiotherapy: the experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 48, Issue:2

    Topics: Administration, Oral; Area Under Curve; Carbon Dioxide; Carcinoma; Carcinoma, Non-Small-Cell Lung; C

1998

Other Studies

9 other studies available for niacinamide and Vomiting

ArticleYear
Efficacious inhaled PDE4 inhibitors with low emetic potential and long duration of action for the treatment of COPD.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Benzamides; Dogs; Ferrets; Humans; Li

2014
Diarrhea is a positive outcome predictor for sorafenib treatment of advanced hepatocellular carcinoma.
    Oncology, 2013, Volume: 84, Issue:1

    Topics: Aged; Aged, 80 and over; Benzenesulfonates; Carcinoma, Hepatocellular; Diarrhea; Female; Follow-Up S

2013
Pellagra revealing a congenital duodenal diaphragm in an adult.
    Clinics and research in hepatology and gastroenterology, 2013, Volume: 37, Issue:6

    Topics: Adult; Diaphragm; Duodenal Obstruction; Female; Humans; Hyperpigmentation; Malnutrition; Niacinamide

2013
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2002, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Domperidone; Dose Fractionation, Radiatio

2002
Metabolites of the radiosensitizer nicotinamide are unlikely to contribute to the degree of emesis observed with the parent drug.
    Oncology research, 2007, Volume: 16, Issue:12

    Topics: Animals; Arteries; Ileum; Isotonic Solutions; Male; Niacinamide; Peristalsis; Radiation-Sensitizing

2007
The effect of nicotinamide on spontaneous and induced activity in smooth and skeletal muscle.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 56, Issue:2

    Topics: Animals; Anura; Culture Techniques; Dose-Response Relationship, Drug; Gastrointestinal Motility; Ile

2000
Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore.
    Singapore medical journal, 2000, Volume: 41, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Complement C3; Diarrhea; Doxycycline; Drug Combinations; Female; Fluore

2000
Synthesis, structure-activity relationships, and pharmacological profile of 9-amino-4-oxo-1-phenyl-3,4,6,7-tetrahydro[1,4]diazepino[6, 7,1-hi]indoles: discovery of potent, selective phosphodiesterase type 4 inhibitors.
    Journal of medicinal chemistry, 2000, Dec-14, Volume: 43, Issue:25

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Anti-Asthmatic Ag

2000
[Metoclopramide does not influence urinary elimination of N-methylnicotinamide and 5-OH-indoleacetic acid].
    Acta vitaminologica et enzymologica, 1968, Volume: 22, Issue:3

    Topics: Adult; Amides; Benzoates; Female; Humans; Indoleacetic Acids; Injections, Intramuscular; Nausea; Nia

1968