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niacinamide and Tuberous Sclerosis

niacinamide has been researched along with Tuberous Sclerosis in 4 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, J1
Samsel, PA1
Narov, K1
Jones, A1
Gallacher, D1
Gallacher, J1
Sampson, JR1
Shen, MH1
Lee, N1
Woodrum, CL1
Nobil, AM1
Rauktys, AE1
Messina, MP1
Dabora, SL1
Cohen, JD1
Tham, KY1
Mastrandrea, NJ1
Gallegos, AC1
Monks, TJ1
Lau, SS1
Singer, EA1
Gupta, GN1
Srinivasan, R1

Reviews

1 review available for niacinamide and Tuberous Sclerosis

ArticleYear
Targeted therapeutic strategies for the management of renal cell carcinoma.
    Current opinion in oncology, 2012, Volume: 24, Issue:3

    Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Clinical Trials as Topic; Disease-F

2012

Other Studies

3 other studies available for niacinamide and Tuberous Sclerosis

ArticleYear
Combination of Everolimus with Sorafenib for Solid Renal Tumors in Tsc2
    Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Cell Death; Cell Line, Tumor; Disease Models, Animal; Dr

2017
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models.
    BMC pharmacology, 2009, Apr-15, Volume: 9

    Topics: Animals; Atorvastatin; Benzenesulfonates; Cystadenoma; Disease Models, Animal; Doxycycline; Drug Eva

2009
cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 122, Issue:2

    Topics: Animals; Benzenesulfonates; Bucladesine; Carcinoma, Renal Cell; Cell Line; Cyclin D1; Cyclin-Depende

2011