Page last updated: 2024-10-19

niacinamide and Triple Negative Breast Neoplasms

niacinamide has been researched along with Triple Negative Breast Neoplasms in 7 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Triple Negative Breast Neoplasms: Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN.

Research Excerpts

ExcerptRelevanceReference
" Because dosing delays and modifications were associated with the MTD, the recommended phase II dose was declared to be pemetrexed 500 mg/m2 every 14 days with oral sorafenib 400 mg given twice daily on days 1-5."2.82Phase I study of pemetrexed with sorafenib in advanced solid tumors. ( Booth, L; Bose, P; Dent, P; Geyer, CE; Gordon, S; Kmieciak, M; Massey, HD; McGuire, WP; Moran, RG; Poklepovic, A; Quigley, M; Roberts, JD; Shafer, DA; Shrader, E; Strickler, K; Tombes, MB; Wan, W, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Jung, M1
Lee, KM1
Im, Y1
Seok, SH1
Chung, H1
Kim, DY1
Han, D2
Lee, CH2
Hwang, EH1
Park, SY1
Koh, J1
Kim, B1
Nikas, IP1
Lee, H2
Hwang, D1
Ryu, HS2
Maric, T1
Bazhin, A1
Khodakivskyi, P1
Mikhaylov, G1
Solodnikova, E1
Yevtodiyenko, A1
Giordano Attianese, GMP1
Coukos, G1
Irving, M1
Joffraud, M1
Cantó, C1
Goun, E1
Song, W1
Hwang, Y1
Youngblood, VM1
Cook, RS1
Balko, JM1
Chen, J1
Brantley-Sieders, DM1
Kim, JY1
Woo, J1
Yue, W1
Kim, K1
Choi, S1
Jang, JJ1
Kim, Y1
Park, IA1
Killock, D1
Poklepovic, A1
Gordon, S1
Shafer, DA1
Roberts, JD1
Bose, P1
Geyer, CE1
McGuire, WP1
Tombes, MB1
Shrader, E1
Strickler, K1
Quigley, M1
Wan, W1
Kmieciak, M1
Massey, HD1
Booth, L1
Moran, RG1
Dent, P1
Liu, CY1
Su, JC1
Huang, TT1
Chu, PY1
Huang, CT1
Wang, WL1
Lau, KY1
Tsai, WC1
Yang, HP1
Shiau, CW1
Tseng, LM1
Chen, KF1

Trials

1 trial available for niacinamide and Triple Negative Breast Neoplasms

ArticleYear
Phase I study of pemetrexed with sorafenib in advanced solid tumors.
    Oncotarget, 2016, 07-05, Volume: 7, Issue:27

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumo

2016

Other Studies

6 other studies available for niacinamide and Triple Negative Breast Neoplasms

ArticleYear
Nicotinamide (niacin) supplement increases lipid metabolism and ROS-induced energy disruption in triple-negative breast cancer: potential for drug repositioning as an anti-tumor agent.
    Molecular oncology, 2022, Volume: 16, Issue:9

    Topics: Animals; Apoptosis; Cell Line, Tumor; Drug Repositioning; Humans; Lipid Metabolism; Mice; Niacin; Ni

2022
A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD
    Biosensors & bioelectronics, 2023, Jan-15, Volume: 220

    Topics: Animals; Biosensing Techniques; Humans; NAD; Niacinamide; Pyridinium Compounds; Triple Negative Brea

2023
Targeting EphA2 impairs cell cycle progression and growth of basal-like/triple-negative breast cancers.
    Oncogene, 2017, 10-05, Volume: 36, Issue:40

    Topics: Animals; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhib

2017
Reconstruction of pathway modification induced by nicotinamide using multi-omic network analyses in triple negative breast cancer.
    Scientific reports, 2017, 06-14, Volume: 7, Issue:1

    Topics: Computational Biology; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Gen

2017
Chemotherapy as a TONIC to invigorate PD-1 inhibition in TNBC.
    Nature reviews. Clinical oncology, 2019, Volume: 16, Issue:8

    Topics: Antineoplastic Agents, Immunological; B7-H1 Antigen; Humans; Niacinamide; Programmed Cell Death 1 Re

2019
Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells.
    Molecular oncology, 2017, Volume: 11, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast; Cell Line, Tumor; Docetaxel; Drug Synergism; Fema

2017