Page last updated: 2024-10-19

niacinamide and Syndrome

niacinamide has been researched along with Syndrome in 25 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"To observe the efficacy and safety of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma (HCC)."9.14[Clinical observation of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma]. ( Chen, MS; Li, P; Lin, XJ; Xu, L; Yuan, YF; Zhang, YQ, 2009)
"Patients with liver fibrosis/cirrhosis and hepatocellular carcinoma were treated with sorafenib 400 mg b."7.78The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma--a pilot study. ( Ferlitsch, A; Peck-Radosavljevic, M; Pinter, M; Reiberger, T; Rohr-Udilova, N; Sieghart, W, 2012)
"Sorafenib (Nexavar) is an oral multi-kinase inhibitor that targets tumor growth and angiogenesis, having encouraging efficacy and tolerability in patients with metastatic renal cell carcinoma (RCC) and other tumors."6.47Sorafenib-associated hand-foot syndrome in Japanese patients. ( Adachi, M; Akaza, H; Fukino, K; Furuse, J; Iijima, M; Minami, H; Murai, M; Naito, S; Tsukamoto, T, 2011)
"Sorafenib (Nexavar) is a targeted therapy acting as VEGFR and PDGFR tyrosine-kinase inhibitor that has been approved in France in the treatment of metastatic renal cell carcinoma and hepatocarcinoma."5.35[Hand-foot syndrome and sorafenib]. ( Desmedt, E; Digue, L; Milano, G; Mortier, L; Ravaud, A, 2009)
"To observe the efficacy and safety of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma (HCC)."5.14[Clinical observation of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma]. ( Chen, MS; Li, P; Lin, XJ; Xu, L; Yuan, YF; Zhang, YQ, 2009)
" Our article focuses on the palmoplantar erythrodysesthesia syndrome, designated also as the hand-foot skin reaction (HFSR), which most frequently occurs in patients treated with TKI sorafenib and sunitinib."4.86[Hand-foot syndrome after administration of tyrosinkinase inhibitors]. ( Bednaríková, D; Kocák, I, 2010)
" This case report discusses an atypical presentation of the hand-foot syndrome in one patient treated with sorafenib."3.80Hand, foot and scrotal blisters in a patient with cancer receiving oral chemotherapy. ( Bella, A; Guerra, JR; Lolo, D; Suelves, AM, 2014)
"Patients with liver fibrosis/cirrhosis and hepatocellular carcinoma were treated with sorafenib 400 mg b."3.78The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma--a pilot study. ( Ferlitsch, A; Peck-Radosavljevic, M; Pinter, M; Reiberger, T; Rohr-Udilova, N; Sieghart, W, 2012)
"One hundred patients with sleep disorders and asthenic syndrome of various etiology and severity were studied."2.90[Clinical efficacy of neurometabolic therapy of dissomical disorders in asthenic syndrome]. ( Esipov, AV; Ivolgin, AF; Kalyagin, IE; Karakozov, AG; Katenko, SV; Kazakov, SP; Khritinin, DF; Levchenko, OB; Molodova, AI, 2019)
"Sorafenib (Nexavar) is an oral multi-kinase inhibitor that targets tumor growth and angiogenesis, having encouraging efficacy and tolerability in patients with metastatic renal cell carcinoma (RCC) and other tumors."2.47Sorafenib-associated hand-foot syndrome in Japanese patients. ( Adachi, M; Akaza, H; Fukino, K; Furuse, J; Iijima, M; Minami, H; Murai, M; Naito, S; Tsukamoto, T, 2011)
"Sorafenib (Nexavar) is a targeted therapy acting as VEGFR and PDGFR tyrosine-kinase inhibitor that has been approved in France in the treatment of metastatic renal cell carcinoma and hepatocarcinoma."1.35[Hand-foot syndrome and sorafenib]. ( Desmedt, E; Digue, L; Milano, G; Mortier, L; Ravaud, A, 2009)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's1 (4.00)18.2507
2000's10 (40.00)29.6817
2010's9 (36.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Esipov, AV1
Ivolgin, AF1
Khritinin, DF1
Katenko, SV1
Kazakov, SP1
Karakozov, AG1
Kalyagin, IE1
Levchenko, OB1
Molodova, AI1
Belov, VG1
Parfenov, IuA1
Okovityĭ, SV1
Guerra, JR1
Suelves, AM1
Bella, A1
Lolo, D1
Markevich, PS1
Markevich, LB1
Plekhanov, AN1
Kovalenko, AL1
Chutko, LS1
Surushkina, SY1
Yakovenko, EA1
Rozhkova, AV1
Anisimova, TI1
Bondarchuk, YL1
Wolber, C1
Udvardi, A1
Tatzreiter, G1
Schneeberger, A1
Volc-Platzer, B1
Milano, G1
Mortier, L1
Digue, L1
Desmedt, E1
Ravaud, A1
Xu, L1
Li, P1
Lin, XJ1
Yuan, YF1
Zhang, YQ1
Chen, MS1
Lipworth, AD1
Robert, C1
Zhu, AX1
Zhang, T1
Ding, X1
Wei, D1
Cheng, P1
Su, X1
Liu, H1
Wang, D1
Gao, H1
Bednaríková, D1
Kocák, I1
Iijima, M1
Fukino, K1
Adachi, M1
Tsukamoto, T1
Murai, M1
Naito, S1
Minami, H1
Furuse, J1
Akaza, H1
Pinter, M1
Sieghart, W1
Reiberger, T1
Rohr-Udilova, N1
Ferlitsch, A1
Peck-Radosavljevic, M1
Rachid, MA1
Demaula, CD1
Scott, DW1
Miller, WH1
Senter, DA1
Myers, S1
THIERS, H1
FORNAINI, G1
PONTREMOLI, S1
DRAGO, U1
FINOTTO, E1
MADDALOSSO, T1
Moriwaka, F1
Govindarajan, R1
Adusumilli, J1
Baxter, DL1
El-Khoueiry, A1
Harik, SI1
Chung, CL1
Cusack, CA1
Chung, NM1
Gutierrez, M1
Turner, ML1
Lai, SE1
Kuzel, T1
Lacouture, ME1
LeWitt, PA1
McDonald, MC1
Filipe, HM1
Thiemermann, C1
Mys'ko, GN1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Re-validating Prophylactic Efficacy of Urea-based Cream on Sorafenib-induced Hand-foot Skin Reaction in Patients With Advanced Hepatocellular Carcinoma[NCT04568330]129 participants (Actual)Interventional2014-03-21Completed
"Evaluation of the Restorative Efficacy of the Cosmetic Product Onco-Repair vs. Placebo on Grade 2 Hand Foot Syndrome Induced by Targeted Therapies or Conventional Chemotherapy. Randomized, Multicentre, Double Blind, Controlled Study Versus Placebo."[NCT03612011]Phase 372 participants (Actual)Interventional2018-07-12Completed
The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction in Patients With Korean Hepatocellular Carcinoma Patients: Multicenter, Prospective Randomized Double-Blind Controlled Study[NCT03212625]Phase 4288 participants (Actual)Interventional2016-01-28Completed
Phase II Study of BAY 43-9006 in Japanese Patients With Renal Cell Carcinoma[NCT00661375]Phase 2131 participants (Actual)Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for niacinamide and Syndrome

ArticleYear
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Sorafenib improves the survival of patients with advanced hepatocellular carcinoma: a meta-analysis of randomized trials.
    Anti-cancer drugs, 2010, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma,

2010
[Hand-foot syndrome after administration of tyrosinkinase inhibitors].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2010, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Foot Dermatoses; Hand Dermatoses; Humans;

2010
Sorafenib-associated hand-foot syndrome in Japanese patients.
    The Journal of dermatology, 2011, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Benzenesulfonates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase

2011
Sorafenib-associated hand-foot syndrome in Japanese patients.
    The Journal of dermatology, 2011, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Benzenesulfonates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase

2011
Sorafenib-associated hand-foot syndrome in Japanese patients.
    The Journal of dermatology, 2011, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Benzenesulfonates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase

2011
Sorafenib-associated hand-foot syndrome in Japanese patients.
    The Journal of dermatology, 2011, Volume: 38, Issue:3

    Topics: Antineoplastic Agents; Benzenesulfonates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase

2011
[Nicotinic acid].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl

    Topics: Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Niacin; Niacinamide; Pellagra; Synd

2004

Trials

4 trials available for niacinamide and Syndrome

ArticleYear
[Clinical efficacy of neurometabolic therapy of dissomical disorders in asthenic syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2019, Volume: 119, Issue:9

    Topics: Administration, Oral; Antioxidants; Asthenia; Drug Combinations; Flavin Mononucleotide; Humans; Inos

2019
[Treatment of alcohol addiction syndrome with cytoflavin].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2013, Volume: 113, Issue:6 Pt 2

    Topics: Adult; Alcoholism; Drug Combinations; Female; Flavin Mononucleotide; Humans; Inosine Diphosphate; Ma

2013
[The efficacy of cytoflavin in the treatment of burnout syndrome].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:10

    Topics: Adult; Antioxidants; Burnout, Professional; Drug Combinations; Female; Flavin Mononucleotide; Humans

2015
[Clinical observation of sorafenib monotherapy in Chinese patients with advanced hepatocellular carcinoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2009, Volume: 31, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Diarrhea; Female;

2009

Other Studies

16 other studies available for niacinamide and Syndrome

ArticleYear
Hand, foot and scrotal blisters in a patient with cancer receiving oral chemotherapy.
    BMJ case reports, 2014, May-19, Volume: 2014

    Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Aged; Blister; Carcinoma, He

2014
[THE PHARMACOTHERAPEUTIC EFFICIENCY OF CYTOFLAVIN IN PATIENTS WITH DIABETIC FOOT SYNDROME: IMMEDIATE AND LONG-TERM RESULTS].
    Klinicheskaia meditsina, 2015, Volume: 93, Issue:6

    Topics: Adult; Aged; Diabetic Foot; Drug Combinations; Female; Flavin Mononucleotide; Humans; Inosine Diphos

2015
Perforating folliculitis, angioedema, hand-foot syndrome--multiple cutaneous side effects in a patient treated with sorafenib.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2009, Volume: 7, Issue:5

    Topics: Aged; Angioedema; Antineoplastic Agents; Benzenesulfonates; Diagnosis, Differential; Drug Eruptions;

2009
[Hand-foot syndrome and sorafenib].
    Bulletin du cancer, 2009, Volume: 96, Issue:2

    Topics: Benzenesulfonates; Dermatology; Drug Eruptions; Foot Dermatoses; Hand Dermatoses; Humans; Kidney Neo

2009
The effects of sorafenib on the portal hypertensive syndrome in patients with liver cirrhosis and hepatocellular carcinoma--a pilot study.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:1

    Topics: Aged; Benzenesulfonates; Carcinoma, Hepatocellular; Female; Humans; Hypertension, Portal; Liver Cirr

2012
Concurrent follicular dysplasia and interface dermatitis in Boxer dogs.
    Veterinary dermatology, 2003, Volume: 14, Issue:3

    Topics: Animals; Dermatitis; Dog Diseases; Dogs; Female; Folliculitis; Immunohistochemistry; Male; Niacinami

2003
[Syndrome of ecchymoses of effort without urticaria; porphyrinuria, improvement with large doses of nicotinamide].
    Lyon medical, 1952, Jul-13, Volume: 187, Issue:28

    Topics: Ecchymosis; Humans; Niacin; Niacinamide; Nicotinic Acids; Porphyrias; Syndrome; Urticaria

1952
[Acute biochemical syndrome caused by excessive doses of vitamin PP: activity of the transketolase and transaldolase reactions].
    Bollettino della Societa italiana di biologia sperimentale, 1960, Mar-15, Volume: 36

    Topics: Niacin; Niacinamide; Nicotinic Acids; Syndrome; Transaldolase; Transferases; Transketolase

1960
[CONSIDERATIONS ON THE USE OF CYANOCOBALAMINE IN HIGH DOSES BY PHLEBOCLYSIS (ASSOCIATED WITH PP VITAMIN, ASCORBIC ACID, FOLIC ACID) IN VARIOUS CLINICAL SITUATIONS (LIVER DISEASES, ANEMIC-DEFICIENT SYNDROMES)].
    Gazzetta medica italiana, 1965, Volume: 124

    Topics: Adolescent; Anemia; Ascorbic Acid; Child; Corrinoids; Folic Acid; Geriatrics; Humans; Injections, In

1965
Reversible posterior leukoencephalopathy syndrome induced by RAF kinase inhibitor BAY 43-9006.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Oct-01, Volume: 24, Issue:28

    Topics: Angiogenesis Inhibitors; Benzenesulfonates; Cholangiocarcinoma; Clinical Trials as Topic; Enzyme Inh

2006
Wells syndrome: an enigmatic and therapeutically challenging disease.
    Journal of drugs in dermatology : JDD, 2006, Volume: 5, Issue:9

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Inflammatory Age

2006
Leukocytoclastic vasculitis masquerading as hand-foot syndrome in a patient treated with sorafenib.
    Archives of dermatology, 2006, Volume: 142, Issue:11

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Non-Small-Cell Lung; Diagnosis, Different

2006
Hand-foot and stump syndrome to sorafenib.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Jan-20, Volume: 25, Issue:3

    Topics: Amputation Stumps; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Eruptions;

2007
The neurotoxicity of the rat poison vacor. A clinical study of 12 cases.
    The New England journal of medicine, 1980, Jan-10, Volume: 302, Issue:2

    Topics: Adult; Brain Diseases; Diabetes Mellitus; Humans; Hypotension, Orthostatic; Male; Middle Aged; Nervo

1980
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Blood Pressure; Creatine Kin

1999
[Several indices of the methylation process in schizophrenic patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1977, Volume: 77, Issue:7

    Topics: Adult; Antipsychotic Agents; Automatism; Catechol O-Methyltransferase; Depression; Female; Hallucina

1977