niacinamide has been researched along with Stroke in 26 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Only three drugs, nicaravene, ebselen and edaravone, all radical scavengers, were judged effective by small-sized trials with a wide therapeutic window, 48-72 hours after stroke, in Japan." | 4.81 | [Neuroprotective therapy for the treatment of acute ischemic stroke]. ( Naritomi, H, 2001) |
| "We have analyzed the results of treatment of 1450 stroke patients." | 2.79 | [The use of neurometabolic treatment in the complex rehabilitation in poststroke patients]. ( Galkin, AS; Khafizova, TL; Kovalchuck, VV, 2014) |
| "Ischemic stroke is one of the leading causes of human death and disability." | 1.72 | Acutely Inhibiting AQP4 With TGN-020 Improves Functional Outcome by Attenuating Edema and Peri-Infarct Astrogliosis After Cerebral Ischemia. ( Hao, X; Li, C; Lin, L; Ren, Y; Sun, C; Tian, J; Yang, Y; Yin, L; Zhang, X, 2022) |
| "Hyperglycemia was induced in rats by the administration of nicotinamide and streptozotocin." | 1.51 | Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats. ( Detante, O; Diekhorst, L; Díez-Tejedor, E; Fuentes, B; Gómez-de Frutos, MC; Gutiérrez-Fernández, M; Jolkkonen, J; Laso-García, F; Martínez-Arroyo, A; Moisan, A; Otero-Ortega, L, 2019) |
| "Stroke is a leading cause of morbidity and mortality." | 1.46 | Nicotinamide Administration Improves Remyelination after Stroke. ( Ding, J; Luan, Y; Qian, C; Teng, GJ; Wang, C; Zhang, Y; Zhao, Z, 2017) |
| "TGN-020 significantly reduced oedema, glial scar, albumin effusion, and apoptosis, at both 3 and 7 days after MCAO." | 1.46 | Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways. ( Balsanu, TA; Bogdan, C; Carare, RO; Divan, T; Margaritescu, C; Mogoanta, L; Muresanu, DF; Pirici, D; Pirici, I; Vitalie, V, 2017) |
| "The use of cytoflavin in the treatment of stroke was accompanied by the earlier and more intense activation of neurotrophic mechanisms in astrocytes, delayed activation of neurotrophic mechanisms in endothelial cells, which promoted neuroprotection in acute ischemic stroke." | 1.42 | [Characteristics of the regulation of neurotrophic mechanisms in ischemic stroke]. ( Gracheva, EV; Kovalenko, AL; Malkova, VM; Trashkov, AP; Tsygan, NV; Vasiliev, AG; Yakovleva, VA, 2015) |
| "It was analysed the results of treatment of 1450 stroke patients." | 1.42 | [Therapeutic possibilities of improvement of cognitive functions, psychoemotional condition and a quality of life in post-stroke patients]. ( Kovalchuk, VV, 2015) |
| " However, the dosage and time of treatment require clarification." | 1.31 | Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model. ( Adams, JD; Chan, P; Chang, ML; Kem, S; Klaidman, LK; Sugawara, T; Yang, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 15 (57.69) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, C | 1 |
| Lin, L | 1 |
| Yin, L | 1 |
| Hao, X | 1 |
| Tian, J | 1 |
| Zhang, X | 1 |
| Ren, Y | 1 |
| Li, C | 1 |
| Yang, Y | 1 |
| Chung, JJ | 1 |
| Jin, T | 1 |
| Poltavskaya, TS | 1 |
| Bazhenov, VA | 1 |
| Volojanin, AV | 1 |
| Belkin, AA | 1 |
| Leiderman, IN | 1 |
| Kovalenko, AL | 3 |
| Rizakhanova, OA | 1 |
| Parfenov, SA | 1 |
| Sapozhnikov, KV | 1 |
| Willyard, C | 1 |
| Wang, C | 1 |
| Zhang, Y | 1 |
| Ding, J | 1 |
| Zhao, Z | 1 |
| Qian, C | 1 |
| Luan, Y | 1 |
| Teng, GJ | 1 |
| Pirici, I | 1 |
| Balsanu, TA | 1 |
| Bogdan, C | 1 |
| Margaritescu, C | 1 |
| Divan, T | 1 |
| Vitalie, V | 1 |
| Mogoanta, L | 1 |
| Pirici, D | 1 |
| Carare, RO | 1 |
| Muresanu, DF | 1 |
| Gómez-de Frutos, MC | 1 |
| Laso-García, F | 1 |
| Diekhorst, L | 1 |
| Otero-Ortega, L | 1 |
| Fuentes, B | 1 |
| Jolkkonen, J | 1 |
| Detante, O | 1 |
| Moisan, A | 1 |
| Martínez-Arroyo, A | 1 |
| Díez-Tejedor, E | 1 |
| Gutiérrez-Fernández, M | 1 |
| Zuloaga, KL | 1 |
| Krasnow, SM | 1 |
| Zhu, X | 1 |
| Zhang, W | 1 |
| Jouihan, SA | 1 |
| Shangraw, RE | 1 |
| Alkayed, NJ | 1 |
| Marks, DL | 1 |
| Kovalchuck, VV | 1 |
| Khafizova, TL | 1 |
| Galkin, AS | 1 |
| Rumiantseva, SA | 3 |
| Silina, EV | 2 |
| Tsukurova, LA | 1 |
| Stupin, VA | 1 |
| Chichanovskaia, LV | 1 |
| Nazarov, MV | 1 |
| Kabaeva, EN | 1 |
| Tsygan, NV | 2 |
| Trashkov, AP | 1 |
| Yakovleva, VA | 1 |
| Malkova, VM | 1 |
| Gracheva, EV | 1 |
| Vasiliev, AG | 1 |
| Kovalchuk, VV | 1 |
| Trofimova, SA | 1 |
| Balunov, OA | 1 |
| Dubinina, EE | 1 |
| Odinak, MM | 1 |
| Skvortsova, VI | 1 |
| Vozniuk, IA | 1 |
| Stakhovskaia, LV | 1 |
| Klocheva, EG | 1 |
| Novikova, LB | 1 |
| Ianishevskiĭ, SN | 1 |
| Golokhvastov, SIu | 1 |
| Guo, JM | 1 |
| Dong, WZ | 1 |
| Liu, AJ | 1 |
| Cheng, MH | 1 |
| Su, DF | 1 |
| Tsuruta, D | 1 |
| Nishikawa, T | 1 |
| Yamagami, J | 1 |
| Hashimoto, T | 1 |
| Bolevich, SB | 1 |
| Men'shova, NI | 1 |
| Asadullaev, MM | 1 |
| Saidvaliev, FS | 1 |
| Shermukhamedova, FK | 1 |
| Rizvonov, ZhK | 1 |
| Vakhabova, NM | 1 |
| Erkebaeva, SK | 1 |
| Nurguzhaev, ES | 1 |
| Gafurov, BG | 1 |
| Tuksanbaeva, GU | 1 |
| Yang, J | 2 |
| Klaidman, LK | 1 |
| Chang, ML | 2 |
| Kem, S | 2 |
| Sugawara, T | 1 |
| Chan, P | 1 |
| Adams, JD | 2 |
| Naritomi, H | 1 |
| Leker, RR | 1 |
| Klaidman, L | 1 |
| Morales, M | 1 |
| Macleod, MR | 1 |
| O'Collins, T | 1 |
| Howells, DW | 1 |
| Donnan, GA | 1 |
| Mokudai, T | 1 |
| Ayoub, IA | 1 |
| Sakakibara, Y | 1 |
| Lee, EJ | 1 |
| Ogilvy, CS | 1 |
| Maynard, KI | 1 |
3 reviews available for niacinamide and Stroke
| Article | Year |
|---|---|
[Neuroprotective therapy for the treatment of acute ischemic stroke].
Topics: Animals; Antioxidants; Antipyrine; Clinical Trials as Topic; Edaravone; Free Radical Scavengers; Hum | 2001 |
Nicaraven Chugai.
Topics: Animals; Antioxidants; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Clinical Trials, Phase I as | 2003 |
Pooling of animal experimental data reveals influence of study design and publication bias.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; Meta-Analysis as Topic; Neuroprotective Age | 2004 |
5 trials available for niacinamide and Stroke
| Article | Year |
|---|---|
[The efficacy of metabolic treatment in the early recovery period of patients with ischemic stroke].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Ischemia; Cognition; Drug Combinat | 2020 |
[The use of neurometabolic treatment in the complex rehabilitation in poststroke patients].
Topics: Adult; Aged; Aged, 80 and over; Drug Combinations; Emotions; Female; Flavin Mononucleotide; Humans; | 2014 |
[Modern methods of energy homeostasis correction in elderly patients].
Topics: Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Drug Adminis | 2014 |
[Efficacy of cytoflavin in patients in the acute ischemic stroke].
Topics: Aged; Drug Combinations; Female; Flavin Mononucleotide; Humans; Inosine Diphosphate; Magnetic Resona | 2010 |
[Assessment of multimodal effect of cytoflavin in the acute brain stroke in patients with metabolic syndrome].
Topics: Administration, Intravenous; Aged; Antioxidants; Drug Combinations; Female; Flavin Mononucleotide; H | 2012 |
18 other studies available for niacinamide and Stroke
| Article | Year |
|---|---|
Acutely Inhibiting AQP4 With TGN-020 Improves Functional Outcome by Attenuating Edema and Peri-Infarct Astrogliosis After Cerebral Ischemia.
Topics: Animals; Aquaporin 4; Brain Edema; Brain Ischemia; Gliosis; Infarction, Middle Cerebral Artery; Magn | 2022 |
Average saturation efficiency filter ASEF-CEST MRI of stroke rodents.
Topics: Amides; Animals; Magnetic Resonance Imaging; Niacinamide; Protons; Rats; Rodentia; Stroke | 2023 |
[Cytoflavin as a modulator of rehabilitation treatment of patients with ischemic stroke complicated by post-intensive care syndrome].
Topics: Brain Ischemia; Critical Care; Drug Combinations; Flavin Mononucleotide; Humans; Inosine Diphosphate | 2020 |
How gut microbes could drive brain disorders.
Topics: alpha-Synuclein; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autism Spectrum Disorder | 2021 |
Nicotinamide Administration Improves Remyelination after Stroke.
Topics: Animals; Demyelinating Diseases; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Niaci | 2017 |
Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways.
Topics: Albumins; Animals; Apoptosis; Aquaporin 4; Arteries; Brain; Brain Ischemia; Caspase 3; Disease Model | 2017 |
Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats.
Topics: Administration, Intravenous; Animals; Brain; Disease Models, Animal; Doublecortin Protein; Humans; H | 2019 |
Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke.
Topics: Analysis of Variance; Animals; Benzoates; Blood Glucose; Blotting, Western; Brain; Diabetes Mellitus | 2014 |
[Characteristics of the regulation of neurotrophic mechanisms in ischemic stroke].
Topics: Animals; Astrocytes; Disease Models, Animal; Drug Combinations; Flavin Mononucleotide; Inosine Dipho | 2015 |
[Therapeutic possibilities of improvement of cognitive functions, psychoemotional condition and a quality of life in post-stroke patients].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition; Drug Combinations; Female; Flavin Mononucleotide | 2015 |
[Perspectives of treatment of patients with ischemic stroke: the place and the role of cytoflavin].
Topics: Aged; Antioxidants; Drug Combinations; Female; Flavin Mononucleotide; Humans; Inosine Diphosphate; I | 2010 |
Nicotinamide postpones stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Genetic Predisposition to Disease; Male; Membrane Potential, Mitochondrial; Niacinamide; Ra | 2012 |
Unilateral bullous pemphigoid without erythema and eosinophil infiltration in a hemiplegic patient.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Autoantigens; Collagen Type XVII; Eosinophils; Hem | 2012 |
[Course of free radical processes and prognosis of ischemic and hemorrhagic stroke].
Topics: Aged; Antioxidants; Biomarkers; Brain Ischemia; Drug Combinations; Female; Flavin Mononucleotide; Fr | 2011 |
[The preventive treatment of stroke in patients with discirculatory encephalopathy with a depressive syndrome].
Topics: Cerebrovascular Disorders; Depressive Disorder; Drug Combinations; Female; Flavin Mononucleotide; Hu | 2012 |
Nicotinamide therapy protects against both necrosis and apoptosis in a stroke model.
Topics: Animals; Apoptosis; Brain; Dose-Response Relationship, Drug; Male; Necrosis; Niacinamide; Rats; Rats | 2002 |
Nicotinamide offers multiple protective mechanisms in stroke as a precursor for NAD+, as a PARP inhibitor and by partial restoration of mitochondrial function.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Disease Models, Animal; Mice; Mice, Inbred B | 2003 |
Delayed treatment with nicotinamide (Vitamin B(3)) improves neurological outcome and reduces infarct volume after transient focal cerebral ischemia in Wistar rats.
Topics: Animals; Brain; Cerebral Infarction; Energy Metabolism; Ischemic Attack, Transient; Male; Motor Acti | 2000 |