niacinamide has been researched along with Spinocerebellar Ataxias in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Spinocerebellar Ataxias: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spinocerebellar ataxia type 1 (SCA1) is a genetic disorder characterized by severe ataxia associated with progressive loss of cerebellar Purkinje cells." | 1.39 | Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1. ( Battaglia, G; Biagioni, F; Bucci, D; Cannella, M; Fazio, F; Gradini, R; Lionetto, L; Mascio, G; Nicoletti, F; Notartomaso, S; Puliti, A; Scarselli, P; Signore, M; Simmaco, M; Weisz, F; Zappulla, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stoyas, CA | 1 |
| Bushart, DD | 1 |
| Switonski, PM | 1 |
| Ward, JM | 1 |
| Alaghatta, A | 1 |
| Tang, MB | 1 |
| Niu, C | 1 |
| Wadhwa, M | 1 |
| Huang, H | 1 |
| Savchenko, A | 1 |
| Gariani, K | 1 |
| Xie, F | 1 |
| Delaney, JR | 1 |
| Gaasterland, T | 1 |
| Auwerx, J | 1 |
| Shakkottai, VG | 1 |
| La Spada, AR | 1 |
| Notartomaso, S | 1 |
| Zappulla, C | 1 |
| Biagioni, F | 1 |
| Cannella, M | 1 |
| Bucci, D | 1 |
| Mascio, G | 1 |
| Scarselli, P | 1 |
| Fazio, F | 1 |
| Weisz, F | 1 |
| Lionetto, L | 1 |
| Simmaco, M | 1 |
| Gradini, R | 1 |
| Battaglia, G | 1 |
| Signore, M | 1 |
| Puliti, A | 1 |
| Nicoletti, F | 1 |
2 other studies available for niacinamide and Spinocerebellar Ataxias
| Article | Year |
|---|---|
Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Topics: Animals; Calcium; Cell Line; Cerebellum; Female; Homeostasis; Humans; Male; Mice; Mice, Inbred C57BL | 2020 |
Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1.
Topics: Amides; Animals; Cerebellum; Chromatography, High Pressure Liquid; Disease Models, Animal; Gene Expr | 2013 |