niacinamide has been researched along with Shock, Septic in 9 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 7.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 3.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| "Sepsis is a common clinical critical disease, which is one of the main causes of septic shock and multiple organ dysfunction syndrome (MODS)." | 1.56 | [Progress of nicotinamide in preventing infection and sepsis]. ( Chen, T; Cheng, L; Liang, H; Liu, K; Liu, Y, 2020) |
| "When nafcillin was added, only cortisol, Dilantin, nicotinamide and reserpine were found to prolong life significantly compared to nafcillin-saline treatment Fatality rates were significantly reduced with cortisol and Dilantin when they were given in association with nafcillin compared to nafcillin-saline treatment." | 1.26 | Biochemically assisted antibiotic treatment of lethal murine Staphylococcus aureus septic shock. ( Burmeister, LF; Smith, IM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, L | 1 |
| Chen, T | 1 |
| Liu, Y | 1 |
| Liu, K | 1 |
| Liang, H | 1 |
| Sahan-Firat, S | 1 |
| Temiz-Resitoglu, M | 1 |
| Guden, DS | 1 |
| Senol, SP | 1 |
| Sari, AN | 1 |
| Cil, M | 1 |
| Unsal, D | 1 |
| Korkmaz, B | 1 |
| Tunctan, B | 1 |
| Malik, KU | 1 |
| Buharalioglu, CK | 1 |
| Szabó, C | 3 |
| Greten, FR | 1 |
| Arkan, MC | 1 |
| Bollrath, J | 1 |
| Hsu, LC | 1 |
| Goode, J | 1 |
| Miething, C | 1 |
| Göktuna, SI | 1 |
| Neuenhahn, M | 1 |
| Fierer, J | 1 |
| Paxian, S | 1 |
| Van Rooijen, N | 1 |
| Xu, Y | 1 |
| O'Cain, T | 1 |
| Jaffee, BB | 1 |
| Busch, DH | 1 |
| Duyster, J | 1 |
| Schmid, RM | 1 |
| Eckmann, L | 1 |
| Karin, M | 1 |
| LeClaire, RD | 1 |
| Kell, W | 1 |
| Bavari, S | 1 |
| Smith, TJ | 1 |
| Hunt, RE | 1 |
| Zingarelli, B | 2 |
| Salzman, AL | 2 |
| Scott, GS | 1 |
| Hake, P | 1 |
| Smith, IM | 1 |
| Burmeister, LF | 1 |
| Fulton, RL | 1 |
1 review available for niacinamide and Shock, Septic
| Article | Year |
|---|---|
Nicotinamide: a jack of all trades (but master of none?).
Topics: Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Humans; Niacinamide; Ox | 2003 |
8 other studies available for niacinamide and Shock, Septic
| Article | Year |
|---|---|
[Progress of nicotinamide in preventing infection and sepsis].
Topics: Humans; Multiple Organ Failure; Niacinamide; Poly(ADP-ribose) Polymerases; Sepsis; Shock, Septic; Vi | 2020 |
NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Gene Expression Regul | 2019 |
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.
Topics: Animals; Apoptosis; Carbolines; Caspase 1; Cell Line; Disease Models, Animal; Humans; I-kappa B Kina | 2007 |
Protective effects of niacinamide in staphylococcal enterotoxin-B-induced toxicity.
Topics: Animals; Cell Division; Cell Line; Cytokines; Enterotoxins; Histocompatibility Antigens Class II; In | 1996 |
Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: potential involvement of polyADP ribosyl synthetase.
Topics: ADP Ribose Transferases; Animals; Blood Pressure; Energy Metabolism; Enzyme Activation; Heart Rate; | 1996 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema | 2000 |
Biochemically assisted antibiotic treatment of lethal murine Staphylococcus aureus septic shock.
Topics: Animals; Drug Synergism; Hydrocortisone; Mice; Nafcillin; Niacinamide; Phenytoin; Reserpine; Shock, | 1977 |
Prevention of endotoxic death with nicotinamide and adenosine triphosphate.
Topics: Adenosine; Adenosine Triphosphate; Animals; Endotoxins; Escherichia coli; Injections, Intraperitonea | 1974 |