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niacinamide and Schizophrenia

niacinamide has been researched along with Schizophrenia in 43 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Increased concentrations of kynurenine pathway metabolites have been reported by several groups for disorders involving psychosis, including schizophrenia and bipolar disorder."7.74Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder. ( Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S, 2008)
"The effectiveness of combined phenazepam, lithium, haloperidol and metabolic drugs (alpha-tocopherol, pyridoxal phosphate, nicotinamide) treatment of patients with slow progredient schizophrenia is analyzed."7.67[Comparative effectiveness of the combined use of fenazepam, haloperidol, lithium and metabolic preparations in treating the psychopathologic disorders with obsessions in slowly progressive schizophrenia]. ( Kadysheva, NM; Kryzhanovskiĭ, GN; Mokhovikov, AN; Mosketi, KV, 1988)
"Increased concentrations of kynurenine pathway metabolites have been reported by several groups for disorders involving psychosis, including schizophrenia and bipolar disorder."3.74Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder. ( Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S, 2008)
"The effectiveness of combined phenazepam, lithium, haloperidol and metabolic drugs (alpha-tocopherol, pyridoxal phosphate, nicotinamide) treatment of patients with slow progredient schizophrenia is analyzed."3.67[Comparative effectiveness of the combined use of fenazepam, haloperidol, lithium and metabolic preparations in treating the psychopathologic disorders with obsessions in slowly progressive schizophrenia]. ( Kadysheva, NM; Kryzhanovskiĭ, GN; Mokhovikov, AN; Mosketi, KV, 1988)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199035 (81.40)18.7374
1990's0 (0.00)18.2507
2000's3 (6.98)29.6817
2010's2 (4.65)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Brown, J2
Iacovelli, L1
Di Cicco, G1
Grayson, B2
Rimmer, L1
Fletcher, J1
Neill, JC2
Wall, MJ2
Ngomba, RT2
Harte, M2
Huang, H1
Zheng, S1
Chen, M1
Xie, L1
Li, Z1
Guo, M1
Wang, J1
Lu, M1
Zhu, X1
Koványi, B1
Csölle, C1
Calovi, S1
Hanuska, A1
Kató, E1
Köles, L1
Bhattacharya, A1
Haller, J1
Sperlágh, B1
Hoffer, A4
Prousky, J1
Seybolt, SE1
BELSANTI, R1
ASHBY, WR1
COLLINS, GH1
BASSETT, M1
DENSON, R1
HEYMAN, JJ2
HALPERN, S1
MERLIS, S1
GAMNA, G1
FORNARI, U1
Miller, CL1
Llenos, IC1
Cwik, M1
Walkup, J1
Weis, S1
Mys'ko, GN2
Mileikovskii, IuA1
Mrochek, JE1
Jolley, RL1
Young, DS1
Turner, WJ1
Cazzullo, CL1
Sacchetti, E1
Smeraldi, E1
Deutsch, M1
Ananth, JV2
Ban, TA2
Molcan, J1
Rakús, A1
Motýlová, A1
Kadysheva, NM1
Mokhovikov, AN1
Mosketi, KV1
Kryzhanovskiĭ, GN1
Smythies, JR1
Alvarez, WC1
Spaide, J1
Tanimukai, H1
Ginther, R1
Bueno, J1
Himwich, HE1
Neumann, H1
Rappaport, M1
Heninger, GR1
Bowers, MB1
Gentili, C1
Borghesi, E1
Kanig, K1
Oesterle, W1
Newbold, HL1
Mosher, LR1
Kety, SS1
Vallely, JF1
Lovegrove, TD1
Hobbs, GE1
Vacaflor, L1
Kekhwa, G1
Sterlin, C1
Baker, GA1
Stone, WN1
Hofling, CK1
Winslow, WW1
Pauling, L1
McGrath, SD1
Altus, MS1

Reviews

2 reviews available for niacinamide and Schizophrenia

ArticleYear
[Biochemical treatment possibilities in psychoses].
    Die Medizinische Welt, 1969, Sep-06, Volume: 36

    Topics: Amino Acids; Ascorbic Acid; Dihydroxyphenylalanine; Humans; Methionine; Niacinamide; Nicotinic Acids

1969
Dietary factors and schizophrenia.
    Ciba Foundation study group, 1970, Volume: 35

    Topics: Ascorbic Acid; Diet; Edible Grain; Humans; Methionine; Niacinamide; Nutritional Physiological Phenom

1970

Trials

7 trials available for niacinamide and Schizophrenia

ArticleYear
Nicotinic acid in the treatment of chronic hospitalized schizophrenic patients: a placebo-controlled clinical study.
    Psychopharmacology bulletin, 1977, Volume: 13, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Huma

1977
The effect of nicotinic acid on the frequency and duration of re-hospitalization of schizophrenic patients; a controlled comparison study.
    International journal of neuropsychiatry, 1966, Volume: 2, Issue:3

    Topics: Clinical Trials as Topic; Follow-Up Studies; Hospitalization; Humans; Niacinamide; Nicotinic Acids;

1966
Nicotinic acid and nicotinamide in the treatment of chronic schizophrenia.
    Canadian Psychiatric Association journal, 1971, Volume: 16, Issue:5

    Topics: Chronic Disease; Clinical Trials as Topic; Evaluation Studies as Topic; Humans; Niacinamide; Nicotin

1971
Nicotinic acid in the treatment of newly admitted schizophrenic patients: a placebo-controlled study.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1972, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Niac

1972
Nicotinic acid in the treatment of schizophrenia.
    The Medical letter on drugs and therapeutics, 1973, Dec-21, Volume: 15, Issue:26

    Topics: Acute Disease; Blood Glucose; Chronic Disease; Clinical Trials as Topic; Humans; Hyperbilirubinemia;

1973
Drug therapy.
    Progress in neurology and psychiatry, 1971, Volume: 26

    Topics: Adolescent; Adult; Antidepressive Agents; Antiparkinson Agents; Butyrophenones; Cannabis; Chlorproth

1971
Letter: nicotinamide treatment: an addendum.
    Schizophrenia bulletin, 1974,Fall, Issue:10

    Topics: Electroconvulsive Therapy; Humans; Niacinamide; Placebos; Schizophrenia; Time Factors

1974

Other Studies

34 other studies available for niacinamide and Schizophrenia

ArticleYear
The comparative effects of mGlu5 receptor positive allosteric modulators VU0409551 and VU0360172 on cognitive deficits and signalling in the sub-chronic PCP rat model for schizophrenia.
    Neuropharmacology, 2022, 05-01, Volume: 208

    Topics: Allosteric Regulation; Animals; Cognition; Niacinamide; Oxazoles; Phencyclidine; Proto-Oncogene Prot

2022
Oscillatory Deficits in the Sub-Chronic PCP Rat Model for Schizophrenia Are Reversed by mGlu5 Receptor-Positive Allosteric Modulators VU0409551 and VU0360172.
    Cells, 2023, 03-16, Volume: 12, Issue:6

    Topics: Animals; Niacinamide; Prefrontal Cortex; Rats; Schizophrenia; Signal Transduction

2023
The potential of the P2X7 receptor as a therapeutic target in a sub-chronic PCP-induced rodent model of schizophrenia.
    Journal of chemical neuroanatomy, 2021, Volume: 116

    Topics: Animals; Animals, Newborn; Drug Delivery Systems; Hallucinogens; Injections, Subcutaneous; Male; Mic

2021
The role of P2X7 receptors in a rodent PCP-induced schizophrenia model.
    Scientific reports, 2016, 11-08, Volume: 6

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Mice; Mice, Knockout; Niacinamide; Phencyclidine; Pipera

2016
Successful treatment of schizophrenia requires optimal daily doses of vitamin B3.
    Alternative medicine review : a journal of clinical therapeutic, 2008, Volume: 13, Issue:4

    Topics: Adrenochrome; Humans; Niacinamide; Schizophrenia; Schizophrenic Psychology; Vitamin B Complex

2008
Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia?
    Medical hypotheses, 2010, Volume: 75, Issue:6

    Topics: Antioxidants; Dopamine; Glutathione; Glutathione Disulfide; Humans; Mitochondria; Mitochondrial Memb

2010
Niacinamide. Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2002, Volume: 7, Issue:6

    Topics: Acute Disease; Animals; Anticonvulsants; Diabetes Mellitus, Type 1; Drug Interactions; Humans; Niaci

2002
[Treatment of chronic schizophrenia by a combination of electroshock, pantothenic acid and nicotinamide].
    Rassegna di studi psichiatrici, 1954, Volume: 43, Issue:1

    Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Niacin; Niacinamide; Nicotinic Acids; P

1954
The effects of nicotinic acid, nicotinamide, and placebo on the chronic schizophrenic.
    The Journal of mental science, 1960, Volume: 106

    Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Schizophrenia

1960
Nicotinamide in the treatment of schizophrenia.
    Diseases of the nervous system, 1962, Volume: 23

    Topics: Humans; Niacin; Niacinamide; Nicotinic Acids; Schizophrenia

1962
THE USE OF NICOTINAMIDE TEST DOSE IN THE ASSESSMENT OF PSYCHOTROPIC DRUGS IN SCHIZOPHRENIC PATIENTS.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Biomedical Research; Chlordiazepoxide; Chlorpromazine; Humans; Imipramine; Lactose; Niacin; Niacinam

1964
NICOTINAMIDE METABOLISM IN SCHIZOPHRENICS, DRUG ADDICTS, AND NORMALS: THE EFFECT OF PSYCHOTROPIC DRUGS AND HORMONES.
    Transactions of the New York Academy of Sciences, 1964, Volume: 26

    Topics: Adrenocorticotropic Hormone; Antidepressive Agents; Drug Users; Estradiol; Hydrocortisone; Lysergic

1964
[ATTEMPTS OF TREATMENT OF SCHIZOPHRENIA WITH ANTIMETABOLITES].
    Giornale di psichiatria e di neuropatologia, 1964, Volume: 92

    Topics: Antimetabolites; Drug Therapy; Humans; Niacin; Niacinamide; Schizophrenia; Triethylenemelamine

1964
Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.
    Neurochemistry international, 2008, Volume: 52, Issue:6

    Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Bipolar Disorder; Brain; Chromatography, High Pressure

2008
[Determination of methylnicotinamide in the blood and urine as a means of controlling neuroleptic treatment effectiveness].
    Vrachebnoe delo, 1982, Issue:1

    Topics: Antipsychotic Agents; Drug Evaluation; Humans; Mental Disorders; Niacinamide; Schizophrenia

1982
[Several indices of the methylation process in schizophrenic patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1977, Volume: 77, Issue:7

    Topics: Adult; Antipsychotic Agents; Automatism; Catechol O-Methyltransferase; Depression; Female; Hallucina

1977
[Excretion of catecholamines and tryptophan derivatives in schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:5

    Topics: Adolescent; Adult; Biogenic Amines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Female; Humans; H

1976
Metabolic response of humans to ingestion of nicotinic acid and nicotinamide.
    Clinical chemistry, 1976, Volume: 22, Issue:11

    Topics: Adult; Alcoholism; Computers; Heart Diseases; Humans; Kinetics; Male; Middle Aged; Niacinamide; Nico

1976
N-methylnicotinamide excretion and affective disorders.
    Psychological medicine, 1976, Volume: 6, Issue:2

    Topics: Adjustment Disorders; Adolescent; Adult; Bipolar Disorder; Depression; Female; Humans; Male; Middle

1976
[Preliminary experiences with nicotinamide administration in schizophrenia (author's transl)].
    Bratislavske lekarske listy, 1978, Volume: 69, Issue:5

    Topics: Adult; Humans; Male; Niacinamide; Schizophrenia

1978
[Comparative effectiveness of the combined use of fenazepam, haloperidol, lithium and metabolic preparations in treating the psychopathologic disorders with obsessions in slowly progressive schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:10

    Topics: Adolescent; Adult; Aged; alpha-Tocopherol; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones;

1988
Letter: Nicotinamide treatment of schizophrenia.
    Lancet (London, England), 1973, Dec-22, Volume: 2, Issue:7843

    Topics: Acute Disease; Adult; Bipolar Disorder; Chronic Disease; Drug Evaluation; Female; Humans; Male; Niac

1973
Use of nicotinic acid and/or nicotinamide in high doses to treat schizophrenia.
    The Canadian journal of psychiatric nursing, 1966, Volume: 7, Issue:8

    Topics: Humans; Niacinamide; Nicotinic Acids; Nursing; Schizophrenia

1966
A chemical treatment for schizophrenia.
    Geriatrics, 1967, Volume: 22, Issue:3

    Topics: Adolescent; Aged; Child; Epinephrine; Female; Humans; Niacinamide; Nicotinic Acids; Schizophrenia

1967
Schizophrenic behavior and urinary tryptophan metabolites associated with cysteine given with and without a monoamine oxidase inhibitor (tranylcypromine).
    Life sciences, 1967, Mar-01, Volume: 6, Issue:5

    Topics: Adult; Catatonia; Creatine; Cysteine; Humans; Indoleacetic Acids; Male; Middle Aged; Niacinamide; Pa

1967
[Clinical and pathophysiologic aspects of the therapy of schizophrenic psychotics with nicotinic acid amide].
    Der Nervenarzt, 1967, Volume: 38, Issue:11

    Topics: Adult; Humans; Middle Aged; Niacinamide; Schizophrenia

1967
Mental health research at a state hospital. An attempt at a balanced program.
    Mental hygiene, 1968, Volume: 52, Issue:1

    Topics: Amantadine; Attitude of Health Personnel; Auditory Perception; Behavior Therapy; Computers; Conditio

1968
Adverse effects of niacin in emergent psychosis.
    JAMA, 1968, Jun-10, Volume: 204, Issue:11

    Topics: Adult; Humans; Lysergic Acid Diethylamide; Male; Niacinamide; Nicotinic Acids; Psychoses, Substance-

1968
[Remarks on the level of transmethylases in schizophrenic patients. In vitro assays].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Nov-30, Volume: 43, Issue:22

    Topics: Betaine; Humans; In Vitro Techniques; Methylation; Niacinamide; Schizophrenia

1967
Niacin and the schizophrenic patient.
    The American journal of psychiatry, 1970, Volume: 127, Issue:4

    Topics: Diazepam; Edema; Gastrointestinal Diseases; Humans; Liver Function Tests; Mental Disorders; Niacinam

1970
LSD-induced psychosis and vitamin B 3 .
    The American journal of psychiatry, 1972, Volume: 128, Issue:9

    Topics: Electroconvulsive Therapy; Humans; Lysergic Acid Diethylamide; Niacinamide; Psychoses, Substance-Ind

1972
Letter: Effects of nutrition on schizophrenia.
    The American journal of psychiatry, 1973, Volume: 130, Issue:12

    Topics: Animals; Celiac Disease; Diet Therapy; Edible Grain; Glutens; Greece; Humans; Milk; Niacinamide; Nic

1973
Letter: Dr. Pauling comments on the comments.
    The American journal of psychiatry, 1974, Volume: 131, Issue:12

    Topics: Drug Evaluation; Humans; Niacinamide; Nicotinic Acids; Schizophrenia; Vitamins

1974
Letter: NAD and chronic schizophrenia.
    The American journal of psychiatry, 1974, Volume: 131, Issue:9

    Topics: Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Humans; NAD; Niacinamide; Nicotinic Aci

1974