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niacinamide and Retinopathy of Prematurity

niacinamide has been researched along with Retinopathy of Prematurity in 1 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Retinopathy of Prematurity: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We tested the hypothesis that recombinant human VEGF-A165b and the serine arginine protein kinase (SRPK) inhibitor, SRPIN340, which controls splicing of the VEGF-A pre-mRNA, prevent neovascularization in a rodent model of retinopathy of prematurity (ROP)."3.79SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity. ( Bates, DO; Dick, AD; Gammons, MV; Harper, SJ, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gammons, MV1
Dick, AD1
Harper, SJ1
Bates, DO1

Other Studies

1 other study available for niacinamide and Retinopathy of Prematurity

ArticleYear
SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.
    Investigative ophthalmology & visual science, 2013, Aug-27, Volume: 54, Issue:8

    Topics: Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Ass

2013