Page last updated: 2024-10-19

niacinamide and Retinal Neovascularization

niacinamide has been researched along with Retinal Neovascularization in 2 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Retinal Neovascularization: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.

Research Excerpts

ExcerptRelevanceReference
"We tested the hypothesis that recombinant human VEGF-A165b and the serine arginine protein kinase (SRPK) inhibitor, SRPIN340, which controls splicing of the VEGF-A pre-mRNA, prevent neovascularization in a rodent model of retinopathy of prematurity (ROP)."3.79SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity. ( Bates, DO; Dick, AD; Gammons, MV; Harper, SJ, 2013)
" Previous reports indicate that sorafenib, an oral multikinase inhibitor, might have a beneficial effect on retinal neovascularization."3.76Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor. ( Eibl, KH; Haritoglou, C; Kampik, A; Kernt, M; Lackerbauer, CA; Liegl, RG; Neubauer, AS; Rueping, J; Ulbig, MW, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gammons, MV1
Dick, AD1
Harper, SJ1
Bates, DO1
Kernt, M1
Liegl, RG1
Rueping, J1
Neubauer, AS1
Haritoglou, C1
Lackerbauer, CA1
Eibl, KH1
Ulbig, MW1
Kampik, A1

Other Studies

2 other studies available for niacinamide and Retinal Neovascularization

ArticleYear
SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity.
    Investigative ophthalmology & visual science, 2013, Aug-27, Volume: 54, Issue:8

    Topics: Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Ass

2013
Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor.
    Growth factors (Chur, Switzerland), 2010, Volume: 28, Issue:3

    Topics: Adult; Aged; Astrocytes; Benzenesulfonates; Cell Survival; Humans; Light; Middle Aged; Niacinamide;

2010