Page last updated: 2024-10-19

niacinamide and Pregnancy

niacinamide has been researched along with Pregnancy in 180 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy."7.72Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004)
"In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections."7.67Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988)
"A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)."7.66Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983)
"A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat."7.66Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979)
"Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response."7.656-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977)
" Maternal serum levels of kynurenine, kynurenic acid, anthranilic acid, tryptophan, nicotinamide and N1-methylnicotinamide were measured in late pregnancy by mass spectrometry (n = 497) and related to the odds ratio of infantile atopic eczema."3.83Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. ( Cooper, C; Crozier, SR; El-Heis, S; Godfrey, KM; Harvey, NC; Inskip, HM; Robinson, SM, 2016)
" Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy."3.72Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004)
"It is known that deaths attributable to pellagra, which is considered to be a disease caused by the disturbance of tryptophan metabolism, have been approximately two-fold higher in women than in men."3.69Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats. ( Shibata, K; Toda, S, 1997)
"In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections."3.67Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988)
" During pregnancy, some of both groups received zinc or nicotinamide-adenine dinucleotide (NAD) or nicotinamide throughout pregnancy and glucose for gestational day (gd) 15 to 19 with E or W."3.66Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia. ( Arima, M; Nakazawa, K; Suzuki, N; Tanaka, H, 1982)
"A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)."3.66Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983)
"A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat."3.66Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979)
"Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response."3.656-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977)
"Up to 8% of pregnant women suffer from preeclampsia (PE), a deadly disease characterized by high blood pressure (BP), blood vessel damage, called endotheliosis (vascular endothelial swelling with narrowing of capillary lumen), and high levels of protein in the urine."2.58Vitamin B ( Fushima, T; Ito, S; Li, F; Oe, Y; Oyanagi, G; Saigusa, D; Sato, E; Sato, H; Sekimoto, A; Takahashi, N, 2018)
"The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed."2.50A review of nicotinamide: treatment of skin diseases and potential side effects. ( Rolfe, HM, 2014)
" High-dose nicotinamide should still, however, be considered as a drug with toxic potential at adult doses in excess of 3 gm/day and unsupervised use should be discouraged."2.41Safety of high-dose nicotinamide: a review. ( Bingley, PJ; Douek, IF; Gale, EA; Gillmor, HA; Knip, M; McLean, AE; Moore, WP, 2000)
"It was recently reported in mice that miscarriage can be prevented through the administration of niacin."1.62Vitamin B3 levels in women who experience first-trimester miscarriage. ( Peek, MJ; Quinlivan, JA; Yakob, NA, 2021)
" Recently developed pharmacokinetic models could explain this phenomenon."1.39Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib. ( Beijnen, JH; de Vries, N; Schinkel, AH; Sparidans, RW; Tang, SC; Wagenaar, E, 2013)
"Pemphigoid gestationis is an autoimmune blistering disease of pregnancy caused by autoantibodies directed against BP180 (type XVII collagen) in the basement membrane zone."1.37Pemphigoid gestationis: current management. ( Intong, LR; Murrell, DF, 2011)
"Perinatal asphyxia was induced by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 16 or 20 min."1.34Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth. ( Bustamante, D; Goiny, M; Herrera-Marschitz, M; Morales, P; Pereyra, JT, 2007)
"Perinatal asphyxia was induced in vivo by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 20 min."1.34Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide. ( Bustamante, D; Gomez-Urquijo, S; Herrera-Marschitz, M; Hökfelt, T; Klawitter, V; Morales, P, 2007)
"Fetal hydrocephalus was induced by single intraperitoneal injection of 8 mg/kg 6-aminonicotinamide (6-AN), a niacinamide antagonist, in Sprague-Dawley rat on day 13 of gestation."1.28Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat. ( Matsumoto, S; Oi, S; Tamaki, N; Taomoto, K; Yamada, H, 1991)

Research

Studies (180)

TimeframeStudies, this research(%)All Research%
pre-1990123 (68.33)18.7374
1990's9 (5.00)18.2507
2000's17 (9.44)29.6817
2010's23 (12.78)24.3611
2020's8 (4.44)2.80

Authors

AuthorsStudies
DeBoer, MD1
Platts-Mills, JA1
Elwood, SE1
Scharf, RJ1
McDermid, JM1
Wanjuhi, AW1
Jatosh, S1
Katengu, S1
Parpia, TC1
Rogawski McQuade, ET1
Gratz, J1
Svensen, E1
Swann, JR1
Donowitz, JR1
Mdoe, P1
Kivuyo, S1
Houpt, ER1
Mduma, E1
Liang, D1
Batross, J1
Fiedler, N1
Prapamontol, T1
Suttiwan, P1
Panuwet, P1
Naksen, W1
Baumert, BO1
Yakimavets, V1
Tan, Y1
D'Souza, P1
Mangklabruks, A1
Sittiwang, S1
Kaewthit, K1
Kohsuwan, K1
Promkam, N1
Pingwong, S1
Ryan, PB1
Barr, DB1
Faingold, MC1
Luquez, C1
Oviedo, A1
Puchulu, F1
Re, M1
Cuny, H1
Bozon, K1
Kirk, RB1
Sheng, DZ1
Bröer, S1
Dunwoodie, SL1
Lee, SR1
Jeong, SH1
Mukae, M1
Kim, SY1
Ko, JW1
Kwun, HJ1
Hong, EJ1
Willyard, C1
Yakob, NA1
Peek, MJ1
Quinlivan, JA1
Brownfoot, F1
Binder, N1
Hastie, R1
Harper, A1
Beard, S1
Tuohey, L1
Keenan, E1
Tong, S1
Hannan, N1
Takahashi, N4
Li, F2
Fushima, T4
Oyanagi, G2
Sato, E4
Oe, Y4
Sekimoto, A4
Saigusa, D2
Sato, H4
Ito, S4
Ear, PH1
Chadda, A1
Gumusoglu, SB1
Schmidt, MS1
Vogeler, S1
Malicoat, J1
Kadel, J1
Moore, MM1
Migaud, ME1
Stevens, HE1
Brenner, C1
Snaidr, VA1
Damian, DL1
Halliday, GM1
Imaruoka, K1
Sugawara, J1
Lee, JH3
Zhang, J2
Flores, L1
Rose, JC1
Massmann, GA2
Figueroa, JP2
Scheller, K1
Röckl, T1
Scheller, C1
Schubert, J1
Tang, SC1
de Vries, N1
Sparidans, RW1
Wagenaar, E1
Beijnen, JH1
Schinkel, AH1
Tian, YJ1
Luo, N1
Chen, NN1
Lun, YZ1
Gu, XY1
Li, Z1
Ma, Q1
Zhou, SS1
Rolfe, HM1
Kinoshita, A1
Kenéz, Á1
Locher, L1
Meyer, U1
Dänicke, S1
Rehage, J1
Huber, K1
El-Heis, S1
Crozier, SR1
Robinson, SM1
Harvey, NC1
Cooper, C1
Inskip, HM1
Godfrey, KM1
Mahdi, AJ1
Gosrani, D1
Chakraborty, M1
Rees, A1
Conner, C1
Wilson, K1
Rayment, R1
Alvares, C1
Townley-Tilson, HW1
Nakada, H1
Hagaman, JR1
Wilder, J1
Li, M1
Jennette, JC1
Maeda, N1
Karumanchi, SA1
Smithies, O1
Smedts, HP2
Rakhshandehroo, M1
Verkleij-Hagoort, AC1
de Vries, JH2
Ottenkamp, J1
Steegers, EA2
Steegers-Theunissen, RP2
Michel, ME1
Alanio, E1
Bois, E1
Gavillon, N1
Graesslin, O1
Szukiewicz, D2
Szewczyk, G1
Mittal, TK1
Rongies, W2
Maslinski, S1
Pyzlak, M1
Stangret, A1
Maslinska, D1
NEUWAHL, FJ1
Wu, YJ1
Zhu, YC1
Chen, H1
Huang, Y1
Wei, Q1
Chen, HJ1
Xie, X1
Li, X1
Zhou, Q1
Yang, YR1
Zeng, H1
Lappas, M1
Permezel, M1
Intong, LR1
Murrell, DF1
Bi, J1
Li, H1
Ye, SQ1
Ding, S1
John, CM1
Ramasamy, R1
Al Naqeeb, G1
Al-Nuaimi, AH1
Adam, A1
Amato, L1
Coronella, G1
Berti, S1
Gallerani, I1
Moretti, S1
Fabbri, P1
Bustamante, D3
Goiny, M2
Aström, G1
Gross, J1
Andersson, K1
Herrera-Marschitz, M3
MARTELLI, G1
CECCACCI, F1
BARTOLOMEI, G1
ROSSI, M1
MISCHEL, W1
SPITALI, R1
QUADRI, G1
COLAJACOMO, A1
VALLERINO, V1
CHIEFFI, O2
COLOMBO, L1
INGALLS, TH4
INGENITO, EF2
CURLEY, FJ3
CHAMBERLAIN, JG8
NELSON, MM1
SMITHBERG, M1
RUNNER, MN1
FILSELL, OH1
JARRETT, IG1
ATKINSON, MR1
CAIGER, P1
MORTON, RK1
MANGIAROTTI, MA1
FELISATI, D1
BERNARDINIJARAMILLO, E1
FRATTA, I2
ZAK, SB2
GREENGARD, P2
SIGG, EB2
HUANG, PC1
LIU, DK1
KAO, MS1
GOLDSTEIN, M1
FRASER, FC7
ROTH, K1
HAGERMAN, DD1
VILLEE, CA1
ROUX, JF1
GORDON, EE1
BAKER, H2
PINSKY, L1
Ftukijwatari, T1
Murakami, M1
Ohta, M1
Kimura, N1
Jin-No, Y1
Sasaki, R1
Shibata, K2
Bruno, EJ1
Ziegenfuss, TN1
Parimala, K1
Peedicayil, J1
Peedicayil, A1
Nelson, N1
Ernest, K1
Ieraci, A1
Herrera, DG1
Hofmann, SC1
Bruckner-Tuderman, L1
Spong, CY1
Das, UN1
Morales, P2
Pereyra, JT1
Klawitter, V1
Gomez-Urquijo, S1
Hökfelt, T1
Skyler, JS1
van Driel, LM1
Helbing, WA1
Isaacs, A1
Lindemans, J1
Uitterlinden, AG1
van Duijn, CM1
Smithells, RW1
Sheppard, S1
Schorah, CJ1
Seller, MJ1
Nevin, NC1
Harris, R1
Read, AP1
Fielding, DW1
Rolig, EC1
Hook, JB2
Bond, JT1
Tanaka, H1
Nakazawa, K1
Suzuki, N1
Arima, M1
Kröger, H1
Grätz, R1
Trasler, DG4
Ohannessian, L1
Zakirov, IZ1
Adizov, IuSh1
Yochim, JM1
Tseng, CY2
Ling, EA2
Wong, WC2
Sotelo, C1
Rio, JP1
Horwitt, MK1
Harper, AE1
Henderson, LM1
McCandless, DW1
Scott, WJ3
Spector, R1
Huntoon, S1
Andersen, HU1
Larsen, PM1
Fey, SJ1
Karlsen, AE1
Mandrup-Poulsen, T1
Nerup, J1
Campbell, JM1
Murphy, MR1
Christensen, RA1
Overton, TR1
Tsai, FC1
Gardner, DK1
Beattie, GM1
Rubin, JS1
Mally, MI1
Otonkoski, T1
Hayek, A1
Aoyagi, K1
Bergsten, P1
Eriksson, UJ1
Ebendal, T1
Hellerström, C2
Toda, S1
McKiernan, SH1
Bavister, BD1
Knip, M1
Douek, IF1
Moore, WP1
Gillmor, HA1
McLean, AE1
Bingley, PJ1
Gale, EA1
Loo, WJ1
Dean, D1
Wojnarowska, F1
Claycomb, WC1
Klinger, W1
Muller, D1
Clark, BR1
Halpern, RM1
Smith, RA1
Ritter, EJ2
Wilson, JG2
Briggs, RM1
Seinsch, W1
Krowke, R1
Berg, P1
Merker, HJ6
Schoental, R1
Scheil, HG2
Claussen, U2
Grote, W8
Biddle, FG1
Rearden, CA1
Rajchgot, H1
Diewert, VM1
Beaudoin, AR1
Lorimer, WS1
Stone, PR1
Kidwell, WR1
Yamada, H1
Oi, S1
Tamaki, N1
Matsumoto, S1
Taomoto, K1
Blomquist, CH1
Hakanson, EY1
Jaster, EH1
Ward, NE1
Sandler, S1
Andersson, A1
Korsgren, O1
Tollemar, J1
Petersson, B1
Groth, CG1
Suh, BH1
Cho, YH1
Gotoh, H1
Nomura, T1
Nakajima, H1
Hasegawa, C1
Sakamoto, Y1
Karolyi, J1
Erickson, RP1
Liu, S1
Horner, JL1
Windle, LM1
Coppock, CE1
Labore, JM1
Lanham, JK1
Nave, DH1
Kuwahara, M1
Chaykin, S1
Myers, GS1
Petrakis, NL1
Lee, M1
Careddu, P1
Marini, A1
Lojkin, ME2
Schardein, JL1
Woosley, ET1
Peltzer, MA1
Kaump, DH1
Metcalf, WK1
Gershbein, LL1
Nogami, H2
Verrusio, AC1
Pollard, DR3
Zappasodi, P1
Fernández, NA1
Burgos, JC1
Roberts, LJ1
Asenjo, CF1
Turbow, MM2
Yamane, H1
Kato, T1
Grillo, G1
Luvarà, A1
Rovere, F1
Gebhardt, DO2
Koroleva, AM1
Grigor'eva, EG1
Borzov, VA1
Schade, GJ1
Brown, RR2
Rose, DP2
Price, JM2
Wolf, H2
Funayama, Y1
Yamashita, H1
Hirsch, GH1
Neubert, D2
Woodard, JC1
Novák, L1
Yess, N1
Barrach, HJ1
Köhler, E1
Novack, L1
Zimmermann, B1
Clark, WH1
Dipaolo, JA1
Kasahara, M2
Lyons, WR1
Knopp, K1
Landauer, W1
Kabarity, A1
Wilson, JT1
Waterman, R1
Schultz, LH1
Hambraeus, L1
Ganich, MM2
Long, SY1
Larsson, KS1
Lohmander, S1
Zens, P1
Rothenwallner, A1
Sudeck, M3
Shih, LY1
Chiancone, FM1
Mainardi, L1
Tenconi, LT1
Tarachand, U1
Eapen, J1
Korabel'shchikova, NI1
Aĭzenberg NN+AIZENBERG, NN1
Lesik, OV1
Kaminetzky, HA1
Frank, O1
Langer, A1
Pinder, S2
Greenbaum, AL2
Fratta, ID1
Courtney, KD1
Valerio, DA1
Braidman, IP1
Heinz, D1
Juchau, MR1
Krasner, J1
Yaffe, SJ1
Abdel-Aziz, A1
Karrar, MA1
Scharfschwerdt, H1
Schulz, W1
Rapoport, S1
Macome, JC1
Bischoff, K1
Bai, RU1
Diczfalusy, E1
Schweichel, JU1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Life Interventions for Childhood Growth and Development In Tanzania[NCT03268902]Phase 2/Phase 31,188 participants (Actual)Interventional2017-09-05Completed
Three-Day Dosing NAD + Study[NCT03707652]8 participants (Actual)Interventional2018-03-12Completed
Randomized Double-blinded Comparative Trial to Study the Add-on Activity of Combination Treatment of Nicotinamide on Progression Free Survival for EGFR Mutated Lung Cancer Terminal Stage Patients Being Treated With Gefitinib or Erlotinib[NCT02416739]Phase 2/Phase 3110 participants (Actual)Interventional2015-03-31Active, not recruiting
A Study of the Pharmacology of 17-Hydroxyprogesterone Caproate in Pregnancy[NCT00409825]Phase 261 participants (Actual)Interventional2006-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in the Area Under the Concentration vs. Time Curve in the Second and Third Trimesters of Pregnancy.

"Change in the area under the concentration vs. time curve in the second and third trimesters of pregnancy.~We compared AUC at each PK study visit. Measurements were obtained at 0, 1, 2, 3, 4, 5, 6, 7 days." (NCT00409825)
Timeframe: Second and third trimesters of pregnancy

Interventionng/ML/day (Mean)
AUC -1AUC - 2
Part 1115136

Reviews

11 reviews available for niacinamide and Pregnancy

ArticleYear
Vitamin B
    The Tohoku journal of experimental medicine, 2018, Volume: 244, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Fetal Development; Humans; Niacinamide; Pre-Eclampsia; Preg

2018
Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety.
    Experimental dermatology, 2019, Volume: 28 Suppl 1

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Chemoprevention; Dermatology; DNA Damage;

2019
A review of nicotinamide: treatment of skin diseases and potential side effects.
    Journal of cosmetic dermatology, 2014, Volume: 13, Issue:4

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Chemical and Drug Induced Liver Inju

2014
Water-soluble vitamins: research update.
    Current sports medicine reports, 2005, Volume: 4, Issue:4

    Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural T

2005
Prediction and prevention of type 1 diabetes: progress, problems, and prospects.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:5

    Topics: Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Female; Forecasting; Humans; Hypoglycemic Agents; I

2007
Niacin-tryptophan relationships for evaluating niacin equivalents.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:3

    Topics: Biological Availability; Child; Dietary Proteins; Female; Food Analysis; Food Labeling; Humans; Infa

1981
Safety of high-dose nicotinamide: a review.
    Diabetologia, 2000, Volume: 43, Issue:11

    Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D

2000
Safety of high-dose nicotinamide: a review.
    Diabetologia, 2000, Volume: 43, Issue:11

    Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D

2000
Safety of high-dose nicotinamide: a review.
    Diabetologia, 2000, Volume: 43, Issue:11

    Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D

2000
Safety of high-dose nicotinamide: a review.
    Diabetologia, 2000, Volume: 43, Issue:11

    Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D

2000
Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites.
    Advances in metabolic disorders, 1965, Volume: 2

    Topics: Adult; Amides; Amines; Chromatography, Ion Exchange; Equipment and Supplies; Female; Hormones; Human

1965
Is insulin a teratogen?
    Teratology, 1972, Volume: 5, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Beak; Brain; Chick Embryo; Congenital Abnormalities; Drug Inte

1972
Developmental pharmacology: a review of its application to clinical and basic science.
    Annual review of pharmacology, 1972, Volume: 12

    Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental;

1972
Excretion of tryptophan metabolites as affected by pregnancy, contraceptive steroids, and steroid hormones.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:6

    Topics: Androsterone; Animals; Contraceptives, Oral; Enzyme Induction; Estradiol; Female; Humans; Hydrocorti

1971

Trials

3 trials available for niacinamide and Pregnancy

ArticleYear
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial.
    PLoS medicine, 2021, Volume: 18, Issue:9

    Topics: Adult; Anti-Infective Agents; Azithromycin; Child Development; Double-Blind Method; Drug Administrat

2021
Possible prevention of neural-tube defects by periconceptional vitamin supplementation.
    Lancet (London, England), 1980, Feb-16, Volume: 1, Issue:8164

    Topics: Abortion, Spontaneous; Ascorbic Acid; Avitaminosis; Clinical Trials as Topic; Drug Combinations; Fem

1980
Kinetics of niacin supplements in lactating dairy cows.
    Journal of dairy science, 1994, Volume: 77, Issue:2

    Topics: Animal Feed; Animals; Body Fluids; Cattle; Digestion; Drug Stability; Duodenum; Female; Fermentation

1994

Other Studies

166 other studies available for niacinamide and Pregnancy

ArticleYear
Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers.
    Environmental research, 2022, Volume: 215, Issue:Pt 2

    Topics: Biomarkers; Child; Chlorpyrifos; Creatinine; Cystine; Cytochromes; Farmers; Fatty Acids; Female; Glu

2022
[Pharmacological and clinical characteristics of Insulin Faster Aspart (Fiasp®)].
    Medicina, 2022, Volume: 82, Issue:5

    Topics: Aged; Blood Glucose; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; Hypoglyc

2022
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice.
    Disease models & mechanisms, 2023, 05-01, Volume: 16, Issue:5

    Topics: Amino Acid Transport Systems, Neutral; Animals; Congenital Abnormalities; Female; Heterozygote; Kidn

2023
Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia.
    The Journal of nutritional biochemistry, 2023, Volume: 116

    Topics: Animals; Dietary Supplements; Female; Fetal Development; Humans; Hyperglycemia; Hypoglycemia; Hypogl

2023
How gut microbes could drive brain disorders.
    Nature, 2021, Volume: 590, Issue:7844

    Topics: alpha-Synuclein; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autism Spectrum Disorder

2021
Vitamin B3 levels in women who experience first-trimester miscarriage.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2021, Volume: 61, Issue:3

    Topics: Abortion, Spontaneous; Animals; Female; Humans; Mice; Niacin; Niacinamide; Pilot Projects; Pregnancy

2021
Nicotinamide and its effects on endothelial dysfunction and secretion of antiangiogenic factors by primary human placental cells and tissues.
    Placenta, 2021, Volume: 109

    Topics: Angiogenesis Inhibitors; Blood Vessels; Cells, Cultured; Endothelium, Vascular; Female; Human Umbili

2021
Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring.
    Cell reports, 2019, 01-22, Volume: 26, Issue:4

    Topics: Animals; Female; Lactation; Liver; Maternal Exposure; Mice; NAD; Neurogenesis; Niacinamide; Postpart

2019
Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide.
    Biochemical and biophysical research communications, 2019, 03-19, Volume: 510, Issue:4

    Topics: Animals; Disease Models, Animal; Female; Glomerulonephritis; Lipopolysaccharides; Lupus Erythematosu

2019
Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Blood Pressure; Dantrolene; Dose-Response Relation

2013
Lower concentrations of B-vitamin subgroups in the serum and amniotic fluid correlate to cleft lip and palate appearance in the offspring of A/WySn mice.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013, Volume: 71, Issue:9

    Topics: Adenine; Alkaline Phosphatase; Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cleft

2013
Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 346, Issue:3

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Trans

2013
Maternal nicotinamide supplementation causes global DNA hypomethylation, uracil hypo-incorporation and gene expression changes in fetal rats.
    The British journal of nutrition, 2014, Volume: 111, Issue:9

    Topics: Animals; Betaine; Brain; Dietary Supplements; DNA; DNA Methylation; Down-Regulation; Epigenesis, Gen

2014
Antenatal betamethasone increases vascular reactivity to endothelin-1 by upregulation of CD38/cADPR signaling.
    Journal of developmental origins of health and disease, 2014, Volume: 5, Issue:1

    Topics: ADP-ribosyl Cyclase 1; Animals; Betamethasone; Blood Pressure; Cyclic ADP-Ribose; Endothelin-1; Fema

2014
Insulin Signaling in Liver and Adipose Tissues in Periparturient Dairy Cows Supplemented with Dietary Nicotinic Acid.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adipose Tissue; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Cat

2016
Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2016, Volume: 46, Issue:10

    Topics: Adult; Age Factors; Biomarkers; Comorbidity; Dermatitis, Atopic; Female; Humans; Infant; Kynurenine;

2016
Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes.
    British journal of haematology, 2018, Volume: 180, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; Humans; Leukemia, Myeloi

2018
Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 11-22, Volume: 113, Issue:47

    Topics: Abortion, Spontaneous; Albuminuria; Animals; Animals, Newborn; Blood Pressure; Body Weight; Disease

2016
Nicotinamide ameliorates a preeclampsia-like condition in mice with reduced uterine perfusion pressure.
    American journal of physiology. Renal physiology, 2017, Feb-01, Volume: 312, Issue:2

    Topics: Animals; Blood Pressure; Embryonic Development; Female; Fetal Growth Retardation; Mice; Niacinamide;

2017
Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects.
    European journal of nutrition, 2008, Volume: 47, Issue:7

    Topics: Adult; Case-Control Studies; Dietary Fats; Female; Heart Defects, Congenital; Humans; Infant, Newbor

2008
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report.
    European journal of obstetrics, gynecology, and reproductive biology, 2010, Volume: 149, Issue:1

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Niacinamid

2010
Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59 Suppl 2

    Topics: Adult; Amniotic Fluid; C-Peptide; Cell Differentiation; Cells, Cultured; Cimetidine; Epithelial Cell

2010
Decrease in expression of histamine H2 receptors by human amniotic epithelial cells during differentiation into pancreatic beta-like cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59 Suppl 2

    Topics: Amnion; C-Peptide; Cell Differentiation; Cell Shape; Cells, Cultured; Epithelial Cells; Female; Huma

2010
Nicotinamide and diabetes mellitus.
    British medical journal, 1947, May-03, Volume: 1, Issue:4504

    Topics: Diabetes Mellitus; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnancy

1947
Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus during pregnancy response to sorafenib.
    Chinese medical journal, 2010, Aug-05, Volume: 123, Issue:15

    Topics: Adult; Antineoplastic Agents; Benzenesulfonates; Female; Humans; Kidney Neoplasms; Neuroectodermal T

2010
The anti-inflammatory and antioxidative effects of nicotinamide, a vitamin B(3) derivative, are elicited by FoxO3 in human gestational tissues: implications for preterm birth.
    The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:12

    Topics: Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Female; Forkhead Box Protein O3; Forkhead

2011
Pemphigoid gestationis: current management.
    Dermatologic clinics, 2011, Volume: 29, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Azathioprine

2011
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.
    Journal of neurochemistry, 2012, Volume: 120, Issue:2

    Topics: Acrylamides; Animals; Brain; Cell Death; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Fem

2012
Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses.
    Current medicinal chemistry, 2012, Volume: 19, Issue:30

    Topics: Animals; Blood Glucose; Catalase; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes, Ges

2012
Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis.
    The Journal of dermatological treatment, 2002, Volume: 13, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Doxycycline; Female; Humans; Niacinamide; Pemphigoid, Bullous; Pregnan

2002
Nicotinamide prevents the long-term effects of perinatal asphyxia on basal ganglia monoamine systems in the rat.
    Experimental brain research, 2003, Volume: 148, Issue:2

    Topics: Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Biogenic Monoamines; Cesarean Section; Female; N

2003
[Clinical studies on the effect of vitamin PP in labor].
    Rivista d'ostetricia e ginecologia pratica, 1952, Volume: 34, Issue:11

    Topics: Biomedical Research; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnan

1952
[Liver function test in pregnancy; effect of trigonellamide (N1-methylnicotinamide chloride) on pyruvic, lactic, and amino acids in the blood in liver insufficiency in pregnancy].
    Rivista d'ostetricia e ginecologia pratica, 1953, Volume: 35, Issue:7

    Topics: Amino Acids; Chlorides; Hepatic Insufficiency; Liver Function Tests; Niacin; Niacinamide; Nicotinic

1953
[Biogenic amines of the placenta. III. Nicotinic acid and nicotinamide content of mature, immature, normal and pathological human placenta].
    Zeitschrift fur Geburtshilfe und Gynakologie, 1957, Volume: 148, Issue:2

    Topics: Biogenic Amines; Female; Humans; Niacin; Niacinamide; Nicotinic Acids; Placenta; Pregnancy

1957
[Effect of nicotinamide on the pyridine coenzyme content of the rat placenta].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Mar-15, Volume: 39

    Topics: Animals; Coenzymes; Female; Niacin; Niacinamide; Placenta; Pregnancy; Pyridines; Rats

1963
[DPN-DPNH, TPN-TPNH and pyridine compound content in the liver of the pregnant rat and fetus and in the placenta after large doses of nicotinamide].
    Bollettino della Societa italiana di biologia sperimentale, 1963, Apr-15, Volume: 39

    Topics: Animals; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; NAD; NADP; Niacin; Niacinamide; Plac

1963
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY INJECTION OF A TERATOGEN IN PREGNANCY.
    Science (New York, N.Y.), 1963, Aug-30, Volume: 141, Issue:3583

    Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Female; Humans; Injections; Mice; Niac

1963
CONGENITAL ABNORMALITIES IN THE RAT RESULTING FROM SINGLE INJECTIONS OF 6-AMINONICOTINAMIDE DURING PREGNANCY.
    The Journal of experimental zoology, 1963, Volume: 153

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Antimetabolites; Brain; Cardiovascular Sy

1963
TERATOGENIC EFFECTS OF HYPOGLYCEMIC TREATMENTS IN INBRED STRAINS OF MICE.
    The American journal of anatomy, 1963, Volume: 113

    Topics: Abnormalities, Drug-Induced; Animals; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred Strains; Niac

1963
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY KNOWN TERATOGEN.
    JAMA, 1964, Mar-14, Volume: 187

    Topics: Alloxan; Animals; Chromosome Aberrations; Cleft Palate; Embryo, Mammalian; Embryo, Nonmammalian; Fem

1964
NICOTINAMIDE NUCLEOTIDE COENZYMES AND GLUCOSE METABOLISM IN THE LIVERS OF FOETAL AND NEWBORN LAMBS.
    The Biochemical journal, 1963, Volume: 89

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Body Weight; Carbohydrate Metabolism; Coenzymes;

1963
[METABOLISM OF GLUCOSE AND FRUCTOSE IN THE HUMAN PLACENTA].
    Rivista di ostetricia e ginecologia, 1963, Volume: 18

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbohydrate Metabolism; Female; Fructose; Glucose; NAD

1963
TERATOGENIC ACTION OF THALIDOMIDE.
    Lancet (London, England), 1964, Mar-28, Volume: 1, Issue:7335

    Topics: Abnormalities, Drug-Induced; Female; Folic Acid; Glutamine; Niacinamide; Pregnancy; Pregnancy Compli

1964
[INFLUENCE OF VITAMIN PP IN THE PROCESS OF ODONTOGENESIS].
    Archivos del Instituto de Farmacologia Experimental (Medicina), 1963, Volume: 15

    Topics: Animals; Animals, Newborn; Bone and Bones; Calcification, Physiologic; Dental Calculus; Dental Carie

1963
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
    Science (New York, N.Y.), 1964, Sep-25, Volume: 145, Issue:3639

    Topics: Animals; Avitaminosis; Chlorpromazine; Diet; Female; Fetal Death; Fetus; Imipramine; Liver; NAD; Nia

1964
THE METABOLISM OF ALPHA-N-MONOMETHYL-L-TRYPTOPHAN (L-ABRIN) IN MAN AND IN NORMAL AND PYRIDOXINE DEFICIENT RATS.
    [Tsa chih] [Journal of the] Alumni of the University of Takau. Gaoxiong yi xue yuan. Tong xue hui, 1964, Jan-28, Volume: 63

    Topics: Abrin; Amino Acids; Body Fluids; Eclampsia; Female; Humans; Kynurenine; Male; Niacin; Niacinamide; P

1964
RESISTANCE OF A-JAX MOUSE EMBRYOS WITH SPONTANEOUS CONGENITAL CLEFT LIP TO THE LETHAL EFFECT OF 6-AMINO-NICOTINAMIDE.
    Journal of medical genetics, 1965, Volume: 2, Issue:2

    Topics: Animals; Cleft Lip; Female; Genetics; Humans; Mice; Niacinamide; Pregnancy; Research; Toxicology

1965
KINETICS OF NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENATION BY HUMAN PLACENTA.
    The Biochemical journal, 1965, Volume: 95

    Topics: Biochemical Phenomena; Biochemistry; Catalysis; Estradiol; Estrone; Female; Humans; Kinetics; NAD; N

1965
CONTENT AND SYNTHESIS OF HEPATIC PYRIDINE NUCLEOTIDES IN FETAL AND NEONATAL RABBITS.
    The American journal of physiology, 1965, Volume: 209

    Topics: Aging; Animals; DNA; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Metabolism; NAD; NADP; N

1965
Congenital malformations after a two-hour inactivation of nicotinamide in pregnant mice.
    British medical journal, 1960, Jul-16, Volume: 2, Issue:5193

    Topics: Animals; Congenital Abnormalities; Mice; Niacin; Niacinamide; Nicotinic Acids; Pregnancy

1960
Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats.
    Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:6

    Topics: Animal Nutritional Physiological Phenomena; Animals; Female; Gestational Age; Humans; Niacin; Niacin

2004
The effect of a nicorandil congener on isolated human myometrium.
    European journal of obstetrics, gynecology, and reproductive biology, 2006, Jun-01, Volume: 126, Issue:2

    Topics: Adult; Area Under Curve; Dysmenorrhea; Female; Humans; Middle Aged; Myometrium; Niacinamide; Obstetr

2006
Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain.
    PLoS medicine, 2006, Volume: 3, Issue:4

    Topics: Animals; Apoptosis; Brain; Central Nervous System Depressants; Ethanol; Female; Fetal Alcohol Spectr

2006
[Bullous pemphigoid: diagnostics and new therapeutic strategies].
    Deutsche medizinische Wochenschrift (1946), 2006, Feb-24, Volume: 131, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy

2006
Protection against prenatal alcohol-induced damage.
    PLoS medicine, 2006, Volume: 3, Issue:4

    Topics: Adult; Animals; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Female; Fetal A

2006
Fetal alcohol syndrome and essential fatty acids.
    PLoS medicine, 2006, Volume: 3, Issue:5

    Topics: Animals; Central Nervous System Depressants; Ethanol; Fatty Acids, Essential; Female; Fetal Alcohol

2006
Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth.
    Experimental brain research, 2007, Volume: 177, Issue:3

    Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Central Nervous System Stimu

2007
Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide.
    Experimental brain research, 2007, Volume: 180, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Cell Count; Disease Models

2007
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
    European heart journal, 2008, Volume: 29, Issue:11

    Topics: Adult; Child; Drug-Related Side Effects and Adverse Reactions; Epidemiologic Methods; Female; Geneti

2008
In vitro renal transport functions of the progeny of rats with streptozotocin-induced diabetes.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:2

    Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport; Diabetes Mellitus, Experimental; Female

1982
Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia.
    Brain & development, 1982, Volume: 4, Issue:6

    Topics: Animals; Brain; Carbonic Anhydrases; Central Nervous System Diseases; Ethanol; Female; Fetal Alcohol

1982
[Effect of L-tryptophan, nicotinamide, L-methionine and 1-methylnicotinamide on the embryotoxic effect of various substances].
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7

    Topics: 6-Aminonicotinamide; Animals; Cyclophosphamide; Drug Interactions; Embryo, Mammalian; Female; Hydrox

1983
Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip.
    Teratology, 1983, Volume: 28, Issue:1

    Topics: 6-Aminonicotinamide; Animals; Cell Fusion; Cleft Lip; Embryo, Mammalian; Female; Mice; Mice, Inbred

1983
[Efficacy of using coamid to treat viral hepatitis in pregnant women].
    Akusherstvo i ginekologiia, 1984, Issue:3

    Topics: Cobalt; Female; Hepatitis, Viral, Human; Humans; Male; Niacinamide; Organometallic Compounds; Pregna

1984
Modulation of uterine sensitivity to decidual induction in the rat by nicotinamide; challenge and extension of a model of progestational differentiation.
    Biology of reproduction, 1984, Volume: 30, Issue:3

    Topics: Animals; Decidua; Embryo Implantation; Female; NAD; NADP; Niacinamide; Pregnancy; Progesterone; Rats

1984
A scanning and transmission electron microscopic study of amoeboid microglial cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
    Journal of anatomy, 1984, Volume: 138 ( Pt 4)

    Topics: 6-Aminonicotinamide; Animals; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Microsco

1984
Cerebellar malformation obtained in rats by early postnatal treatment with 6-aminonicotinamide. Role of neuron-glia interactions in cerebellar development.
    Neuroscience, 1980, Volume: 5, Issue:10

    Topics: 6-Aminonicotinamide; Animals; Cell Movement; Cerebellar Cortex; Cerebellum; Dendrites; Female; Micro

1980
The effect of 6-aminonicotinamide on energy metabolism in rat embryo neural tube.
    Teratology, 1981, Volume: 23, Issue:3

    Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Brain; Central Nervous System; Embryo, Mammali

1981
No effect of maternal niacin deficiency on niacin metabolism in newborn brain.
    Neurochemical research, 1981, Volume: 6, Issue:5

    Topics: Animals; Animals, Newborn; Brain; Cerebellum; Female; In Vitro Techniques; Kinetics; Maternal-Fetal

1981
Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide.
    Diabetes, 1995, Volume: 44, Issue:4

    Topics: Animals; Arginine; Electrophoresis, Gel, Two-Dimensional; Female; Interleukin-1; Islets of Langerhan

1995
Nicotinamide, a component of complex culture media, inhibits mouse embryo development in vitro and reduces subsequent developmental potential after transfer.
    Fertility and sterility, 1994, Volume: 61, Issue:2

    Topics: Animals; Blastocyst; Cleavage Stage, Ovum; Culture Media; Culture Techniques; Embryo Transfer; Embry

1994
Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.
    Diabetes, 1996, Volume: 45, Issue:9

    Topics: Abortion, Induced; Animals; C-Peptide; Cell Aggregation; Cell Communication; Cell Differentiation; C

1996
In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16.
    Biology of the neonate, 1997, Volume: 71, Issue:1

    Topics: Animals; Cells, Cultured; Female; Gestational Age; Glucose; Insulin; Insulin Secretion; Islets of La

1997
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:7

    Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Horm

1997
Culture of one-cell hamster embryos with water soluble vitamins: pantothenate stimulates blastocyst production.
    Human reproduction (Oxford, England), 2000, Volume: 15, Issue:1

    Topics: Animals; Blastocyst; Choline; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relations

2000
A severe persistent case of recurrent pemphigoid gestationis successfully treated with minocycline and nicotinamide.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Immunosuppressive Agents; Minocycline; Niacinamide; Pe

2001
Inhibition of DNA synthesis in differentiating cardiac muscle by NAD.
    FEBS letters, 1976, Jan-15, Volume: 61, Issue:2

    Topics: Animals; Animals, Newborn; Biological Transport, Active; Cell Differentiation; DNA Replication; Fema

1976
Developmental aspects of xenobiotic transformation.
    Environmental health perspectives, 1976, Volume: 18

    Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochro

1976
A fluorimetric method for quantitation in the picomole range of N1-methylnicotinamide and nicotinamide in serum.
    Analytical biochemistry, 1975, Volume: 68, Issue:1

    Topics: Female; Humans; Hypercholesterolemia; Kinetics; Male; Microchemistry; Niacinamide; Pregnancy; Pregna

1975
Inhibition of ATP synthesis associated with 6-aminonicotinamide (6-AN) teratogenesis in rat embryos.
    Teratology, 1975, Volume: 12, Issue:3

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Dinitrophenols; F

1975
Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans.
    Clinics in plastic surgery, 1976, Volume: 3, Issue:4

    Topics: Ascorbic Acid; Calcium; Cleft Lip; Cleft Palate; Female; Folic Acid; Humans; Infant, Newborn; Matern

1976
[Embryonic development of hypophysis, adrenal glands and gonads in rat embryos after 6-aminonicotinamide administration].
    Verhandlungen der Anatomischen Gesellschaft, 1976, Issue:70 Pt 1

    Topics: 6-Aminonicotinamide; Adrenal Glands; Animals; Endoplasmic Reticulum; Female; Gonads; Maternal-Fetal

1976
Effects of cytosine arabinoside, 6-aminonicotinamide, and 6-mercaptopurine riboside on ectoderm and mesoderm of mouse limb buds.
    Teratology, 1977, Volume: 15, Issue:2

    Topics: 6-Aminonicotinamide; Animals; Cytarabine; DNA; Ectoderm; Embryo, Mammalian; Extremities; Female; Glu

1977
The role of nicotinamide and of certain other modifying factors in diethylnitrosamine carcinogenesis: fusaria mycotoxins and "spontaneous" tumors in animals and man.
    Cancer, 1977, Volume: 40, Issue:4 Suppl

    Topics: Animals; Diethylnitrosamine; Female; Fusarium; Gastrointestinal Neoplasms; Genital Neoplasms, Female

1977
Effect of 6-aminonicotinamide in teratogenic doses on the DNA- and RNA-concentration in rabbit embryos.
    Teratology, 1977, Volume: 16, Issue:3

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; DNA; Dose-Response Relationship, Drug; Em

1977
6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis.
    Teratology, 1977, Volume: 16, Issue:3

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship,

1977
A selection experiment for distinct types of 6-aminonicotinamide-induced cleft lip in mice.
    Teratology, 1978, Volume: 18, Issue:1

    Topics: 6-Aminonicotinamide; Animals; Cleft Lip; Crosses, Genetic; Face; Female; Genotype; Male; Mice; Mice,

1978
Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat.
    Teratology, 1979, Volume: 19, Issue:2

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship,

1979
NAD precursors as antiteratogens against aminothiadiazole.
    Teratology, 1976, Volume: 13, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Resorption; Gestational Age; Kynurenine; Ma

1976
Control of histone H1 dimer-poly(ADP-ribose) complex formation by poly(ADP-ribose) glycohydrolase.
    Experimental cell research, 1977, Volume: 106, Issue:2

    Topics: Animals; Breast Neoplasms; Cell Line; Cell Nucleus; Female; Glycoside Hydrolases; Histones; Humans;

1977
Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat.
    Neurologia medico-chirurgica, 1991, Volume: 31, Issue:6

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Brain; Dandy-Walker Syndrome; Disease Mod

1991
Pyridine nucleotide levels under conditions of 5 alpha-dihydrotestosterone-stimulated 17 beta-estradiol formation from estrone and pathway of nicotinamide adenine dinucleotide biosynthesis in placental villi in vitro.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:1

    Topics: Chorionic Villi; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Kinetics; NAD; NADP; Niaci

1991
Supplemental nicotinic acid or nicotinamide for lactating dairy cows.
    Journal of dairy science, 1990, Volume: 73, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood Glucose; Body Weight; Cattle; Eating; Fatty Acids

1990
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
    Diabetes, 1989, Volume: 38 Suppl 1

    Topics: Culture Techniques; Female; Glucose; Humans; Insulin; Islets of Langerhans; Niacinamide; Pancreas; P

1989
A comparative study on the NAD glycohydrolase of the maternal and neonatal erythrocytes.
    Asia-Oceania journal of obstetrics and gynaecology, 1985, Volume: 11, Issue:2

    Topics: Enzyme Activation; Erythrocytes; Female; Fetal Blood; Humans; Infant, Newborn; N-Glycosyl Hydrolases

1985
An electron microscopical study of epiplexus and supraependymal cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
    Journal of anatomy, 1985, Volume: 140 ( Pt 1)

    Topics: 6-Aminonicotinamide; Animals; Cerebral Ventricles; Choroid Plexus; Ependyma; Female; Hydrocephalus;

1985
Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Fem

1988
Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains.
    Teratology, 1988, Volume: 37, Issue:3

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Male; Mice; Mice, I

1988
Effects of whole cottonseed, niacin, and niacinamide on in vitro rumen fermentation and on lactating Holstein cows.
    Journal of dairy science, 1988, Volume: 71, Issue:12

    Topics: Animals; Cattle; Cottonseed Oil; Female; Fermentation; In Vitro Techniques; Lactation; Niacin; Niaci

1988
Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus).
    The Journal of biological chemistry, 1973, Jul-25, Volume: 248, Issue:14

    Topics: Animals; Azaserine; Carbon Isotopes; Chorionic Gonadotropin; Embryo Implantation; Embryo, Mammalian;

1973
Effect of 6-aminonicotinamide and of added vitamin A on fusion of embryonic rat palates in vitro.
    The Journal of nutrition, 1967, Volume: 93, Issue:3

    Topics: Animals; Autoradiography; Cleft Palate; Culture Media; Female; In Vitro Techniques; Maternal-Fetal E

1967
Stimulating bilirubin conjugation.
    Lancet (London, England), 1968, May-04, Volume: 1, Issue:7549

    Topics: Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Niacinamide; Pregnancy;

1968
Effect of levels of nitrogen intake on tryptophan metabolism and requirement for pregnancy of the rat.
    The Journal of nutrition, 1967, Volume: 91, Issue:1

    Topics: Animals; Female; Glutamates; Glycine; Male; Niacinamide; Nitrogen; Nucleotides; Pregnancy; Pregnancy

1967
Effects of acute vitamin replacement therapy on 6-aminonicotinamide induced cleft palate late in rat pregnancy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy;

1967
Congenital malformations induced by 6-aminonicotinamide in rabbit kits.
    Experimental and molecular pathology, 1967, Volume: 6, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Eye Abnormalities; Female; Niacinamide; Pregnancy; Pregnancy,

1967
Development of cleft palate induced by 6-aminonicotinamide late in rat gestation.
    The Anatomical record, 1966, Volume: 156, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy;

1966
Failure of steroid hormones to reverse the toxic effects of 6-aminonicotinamide given early in pregnancy.
    Life sciences, 1967, Jan-15, Volume: 6, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Estrone; Female; Fetal Death; Mice; Niacinami

1967
The relation of vitamin-B complex to the effect of thalidomide on the sensitivity of intracellular haemoglobin to oxidation.
    Developmental medicine and child neurology, 1967, Volume: 9, Issue:1

    Topics: Animals; Erythrocytes; Female; Glutethimide; Hemoglobins; Male; Niacinamide; Oxidation-Reduction; Ph

1967
Effect of transplanted tumor and various agents on liver regeneration during pregnancy.
    Rivista di patologia nervosa e mentale, 1966, Volume: 87, Issue:4

    Topics: Animals; Benzofurans; Carcinoma 256, Walker; Female; Fetal Death; Hepatectomy; Liver Regeneration; N

1966
Pathogenesis of spinal malformations induced in the embryos of mice.
    The Journal of bone and joint surgery. American volume, 1967, Volume: 49, Issue:8

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Lumbar Vertebrae; Mice; Niacinamide

1967
A cytoplasmically transmitted, diet-dependent difference in response to the teratogenic effects of 6-aminonicotinamide.
    Science (New York, N.Y.), 1968, Apr-12, Volume: 160, Issue:3824

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Diet; Extrachromosomal Inheritance; Female; Hybr

1968
6-aminonicotinamide-induced skeletal malformations in mice.
    Archives of environmental health, 1968, Volume: 16, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Bone and Bones; Cleft Palate; Female; Fetal D

1968
Nutritional status in Puerto Rican slum area.
    The American journal of clinical nutrition, 1968, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Aged; Anthropometry; Child; Child, Preschool; Deficiency Diseases; Diet; Erythroc

1968
Direct effects of 6-aminonicotinamide on the developing rat embryo in vitro and in vivo.
    Teratology, 1968, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Amnion; Animals; Antimetabolites; Cleft Palate; Culture Media; Culture

1968
[Experimental studies on the development of malformations of the extremities. 2. On the process of the development of tibia defects].
    Nihon Seikeigeka Gakkai zasshi, 1968, Volume: 42, Issue:7

    Topics: Abnormalities, Drug-Induced; Animals; Female; Maternal-Fetal Exchange; Mice; Niacinamide; Pregnancy;

1968
[Metoclopramide does not influence urinary elimination of N-methylnicotinamide and 5-OH-indoleacetic acid].
    Acta vitaminologica et enzymologica, 1968, Volume: 22, Issue:3

    Topics: Adult; Amides; Benzoates; Female; Humans; Indoleacetic Acids; Injections, Intramuscular; Nausea; Nia

1968
The effects of starvation or of treatment with cytotoxic agents on pregnancy in mice.
    Journal of reproduction and fertility, 1969, Volume: 19, Issue:3

    Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dactinomycin; Embryo, Mammalian; Embryonic

1969
[Use of hemotransfusion in the complex therapy of anemias during hypotonic hemorrhages in labor].
    Problemy gematologii i perelivaniia krovi, 1969, Volume: 14, Issue:6

    Topics: Anemia, Hypochromic; Ascorbic Acid; Blood Transfusion; Female; Hematopoiesis; Humans; Iron; Niacinam

1969
Is there an optimal stage for the induction of cleft palate in the mouse?
    The Cleft palate journal, 1969, Volume: 6

    Topics: Animals; Cleft Palate; Cyclophosphamide; Dexamethasone; Female; Mice; Niacinamide; Pregnancy; Pregna

1969
Tryptophan metabolism as affected by anovulatory agents.
    Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1

    Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kyn

1969
[Clinical and experimental studies of delta phalanx of the hallux].
    Seikeigeka. Orthopedic surgery, 1969, Volume: 20, Issue:14

    Topics: Abnormalities, Drug-Induced; Animals; Child; Child, Preschool; Female; Hallux; Humans; Infant, Newbo

1969
Stimulation of renal organic acid transport and protein synthesis by penicillin.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 174, Issue:1

    Topics: Aminohippuric Acids; Ammonium Chloride; Animals; Biological Transport, Active; Body Fluids; Body Wei

1970
Variations in drug metabolism during mammalian development genetic aspects.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Animals; Biotransformation; Embryo, Mammalian; Enzyme Induction; Female; Fetus; Genetic Variation; M

1970
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
    The Journal of nutrition, 1970, Volume: 100, Issue:10

    Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Developme

1970
[Disturbances of tooth development in rat embryos following administration of 6-aminonicotinamide].
    Experientia, 1970, Oct-15, Volume: 26, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Incisor; Microscopy, Electron; Niac

1970
Further studies on a cytoplasmically transmitted difference in response to the teratogen 6-aminonicotinamide.
    Teratology, 1968, Volume: 1, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Diet; Extrachromosomal Inheritance; F

1968
Biochemical studies of the embryotoxic action of 6-aminonicotinamide.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4

    Topics: Abnormalities, Drug-Induced; Acetates; Aspartic Acid; Carbon Isotopes; DNA; Embryo, Mammalian; Embry

1970
Electron microscope studies on the effect of 6-aminonicotinamide on mammalian embryos.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Culture Techniques; Ectoderm; Embryo, Mammalian; Female

1970
Embryonic abnormalities in hamsters following intrauterine injection of 6-aminonicotinamide.
    Teratology, 1971, Volume: 4, Issue:4

    Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Anophthalmos; Brain; Cleft Palate; Cricetinae;

1971
The effects of intraamniotic injection of dexamethasone in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 138, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Cleft Palate; Dexamethasone; Drug Synergism; Ext

1971
Influence of maternal age and parity on fetal mortality and congenital abnormalities induced in rats.
    Growth, 1971, Volume: 35, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Eye Abnormalities; Female; Feta

1971
[Ambulatory therapy of pregnancy toxicoses].
    Zeitschrift fur Allgemeinmedizin, 1970, Mar-20, Volume: 46, Issue:8

    Topics: Ambulatory Care; Ascorbic Acid; Female; Fetus; Folic Acid; Humans; Niacinamide; Pre-Eclampsia; Pregn

1970
[Disturbed embryonic mitosis in rabbits after administration of 6-aminonicotinic acid amide].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:2

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Embryo, Mammalian; Female; Fibroblasts; Liver; Mitosis

1972
[Experiments on the induction and prevention of malformations in rabbits].
    Zeitschrift fur Morphologie und Anthropologie, 1972, Volume: 63, Issue:3

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Animals, Newborn; Antimetabolites; Cell Division; Cong

1972
Nicotinic acid loading of normal cows: effects on blood metabolites and excretory forms.
    Journal of dairy science, 1972, Volume: 55, Issue:10

    Topics: Administration, Oral; Animals; Blood Glucose; Cattle; Diuresis; Fatty Acids, Nonesterified; Female;

1972
[Vitamins. 9. Niacin].
    Lakartidningen, 1972, Oct-23, Volume: 69

    Topics: Adult; Ascorbic Acid Deficiency; Developing Countries; Diet; Female; Food; Humans; Infant; Infant Nu

1972
6-Aminonicotinamide (6-AN)-induced abnormalities of the developing ependyma and choroid plexus as seen with the scanning electron microscope.
    Teratology, 1972, Volume: 6, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cell Membrane; Choroid Plexus; Cilia; Ependyma; Female; Fetus;

1972
[Vitamins C, PP and B-6 in the blood and placenta in the developmental dynamics of pregnancy and labor normally and in obstetrical pathology].
    Pediatriia, 1973, Volume: 52, Issue:2

    Topics: Ascorbic Acid; Blood Chemical Analysis; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Lab

1973
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
    Journal of embryology and experimental morphology, 1973, Volume: 30, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; F

1973
Cell proliferation in the cranial base of A-J mice with 6-AN-induced cleft palate.
    Teratology, 1973, Volume: 8, Issue:2

    Topics: Animals; Autoradiography; Cartilage; Cell Division; Cleft Lip; Cleft Palate; Female; Fetus; Gestatio

1973
A survey of the embryotoxic effects of TCDD in mammalian species.
    Environmental health perspectives, 1973, Volume: 5

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Amines; Animals; Cleft Palate; Cyclo

1973
[Preliminary teratological experiments with mini-pigs ("Göttinger miniaturschwein") (author's transl)].
    Klinische Wochenschrift, 1973, Volume: 21, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; Gestational Age; Niacinamide;

1973
[Experimental studies on the boundary sensitive phase of embryonal development of "Göttingen miniature pigs"].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Embryonic and Fetal Developm

1973
Relation of mandible growth to palate closure in mice.
    Teratology, 1974, Volume: 9, Issue:2

    Topics: Amines; Animals; Body Weight; Cleft Palate; Cortisone; Female; Gestational Age; Mandible; Maxillofac

1974
[Tryptophan metabolism in screening metabolic diseases of the newborn].
    Acta vitaminologica et enzymologica, 1973, Volume: 27, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Evaluation Studies as Topic; Female; Humans; Infant, Newborn;

1973
[Phase-specific pattern of malformation in the Goettinger miniature pig following administration of 6-amino-nicotinamide].
    Zeitschrift fur Morphologie und Anthropologie, 1974, Volume: 65, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Female; Fetus; Injections, Intraperitonea

1974
[Vitamins C, PP and B6 in the blood and placenta in the dynamics of the development of pregnancy and labor normally and in obstetrical pathology].
    Pediatriia akusherstvo i ginekologiia, 1973, Volume: 2

    Topics: Ascorbic Acid; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Labor Complications; Placent

1973
The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1974, Volume: 136

    Topics: Adolescent; Adult; Aged; Androgens; Animals; Estrogens; Female; Humans; Hydrocortisone; Hydrolases;

1974
[Effect of 6-aminonicotinic acid amide in teratogenic dosis on the ATP-concentration in rabbit embryos].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:6

    Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Amines; Animals; Embryo, Mammalian; Female; Nia

1974
Effect of streptozotocin-diabetes on in vivo protein synthesis by placenta and liver of mice.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: 6, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Carbon Radioisotopes; Diabetes Mellitus; Female; Insulin; Leuci

1974
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
    Akusherstvo i ginekologiia, 1974, Issue:9

    Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine;

1974
The effects of intravenously administered water-soluble vitamins during labor in normovitaminemic and hypovitaminemic gravidas on maternal and neonatal blood vitamin levels at delivery.
    American journal of obstetrics and gynecology, 1974, Nov-01, Volume: 120, Issue:5

    Topics: Adolescent; Adult; Ascorbic Acid; Avitaminosis; Biotin; Female; Folic Acid; Humans; Infant, Newborn;

1974
Reduction of 6-aminonicotinamide teratogenicity in mice by etherization.
    Teratology, 1970, Volume: 3, Issue:4

    Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Animals; Cleft Lip; Ether; Ethyl Ethers; Female

1970
Induction of a cytoplasmic factor increasing resistance to the teratogenic effect of 6-aminonicotinamide in mice.
    Teratology, 1973, Volume: 7, Issue:3

    Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Enzyme Induction

1973
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Deficiency Diseases; Desoxycorticosterone; Dex

1966
The pathway of synthesis of mammary-gland nicotinamide-adenine dinucleotide.
    The Biochemical journal, 1967, Volume: 102, Issue:2

    Topics: Animals; Female; Lactation; Liver; Mammary Glands, Animal; NAD; Niacinamide; Pregnancy; Rats

1967
The pathway of biosynthesis of nicotinamide-adenine dinucleotide in rat mammary gland.
    The Biochemical journal, 1968, Volume: 107, Issue:1

    Topics: Animals; Female; Glucosyltransferases; Kinetics; Lactation; Mammary Glands, Animal; Models, Biologic

1968
Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures.
    The Journal of nutrition, 1970, Volume: 100, Issue:1

    Topics: Amino Acids; Animals; Deficiency Diseases; Diet; Dietary Proteins; Feces; Female; Fetal Death; Fetus

1970
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
    Laboratory animal care, 1969, Volume: 19, Issue:5

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma

1969
Teratology in the Macaca mulatta.
    Teratology, 1968, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Clomiphene; Encephalocele; Female; Fetal Death; Haplo

1968
[Induction and prevention of developmental abnormalities in rabbits by administration of 6-aminonicotinic acid and nicotinic acid amide].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:6

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Female; Fetus; Gestational Age; Microphthalmos; Mouth

1971
Studies on reduction of azo-linkages in human placental homogenates.
    Biochemical pharmacology, 1968, Volume: 17, Issue:9

    Topics: Azo Compounds; Carbon Monoxide; Edetic Acid; Female; Flavins; Glucosephosphate Dehydrogenase; Glutat

1968
Effect of some beta-pyridyl derivatives and of histamine on the rat uterus under different functional states.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:2

    Topics: Animals; Estrus; Ethanolamines; Female; Histamine; Histamine H1 Antagonists; Kymography; Methanol; N

1969
[The stabilization of glucose-6-phosphate dehydrogenase in the rat mammary gland].
    Acta biologica et medica Germanica, 1969, Volume: 23, Issue:4

    Topics: Animals; Female; Glucosephosphate Dehydrogenase; Glutathione; Hexosephosphates; In Vitro Techniques;

1969
Factors influencing placental steroidogenesis.
    Steroids, 1972, Volume: 20, Issue:4

    Topics: 17-Ketosteroids; Adenosine Triphosphate; Androstenes; Animals; Carbon Isotopes; Cholesterol; Chorion

1972
The morphology of various types of cell death in prenatal tissues.
    Teratology, 1973, Volume: 7, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cell Survival; Cyclophosphamide; Dactinomycin; Embryo, Mammali

1973