niacinamide has been researched along with Pregnancy in 180 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy." | 7.72 | Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004) |
| "In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections." | 7.67 | Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988) |
| "A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)." | 7.66 | Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983) |
| "A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat." | 7.66 | Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979) |
| "Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response." | 7.65 | 6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977) |
| " Maternal serum levels of kynurenine, kynurenic acid, anthranilic acid, tryptophan, nicotinamide and N1-methylnicotinamide were measured in late pregnancy by mass spectrometry (n = 497) and related to the odds ratio of infantile atopic eczema." | 3.83 | Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. ( Cooper, C; Crozier, SR; El-Heis, S; Godfrey, KM; Harvey, NC; Inskip, HM; Robinson, SM, 2016) |
| " Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy." | 3.72 | Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004) |
| "It is known that deaths attributable to pellagra, which is considered to be a disease caused by the disturbance of tryptophan metabolism, have been approximately two-fold higher in women than in men." | 3.69 | Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats. ( Shibata, K; Toda, S, 1997) |
| "In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections." | 3.67 | Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988) |
| " During pregnancy, some of both groups received zinc or nicotinamide-adenine dinucleotide (NAD) or nicotinamide throughout pregnancy and glucose for gestational day (gd) 15 to 19 with E or W." | 3.66 | Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia. ( Arima, M; Nakazawa, K; Suzuki, N; Tanaka, H, 1982) |
| "A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)." | 3.66 | Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983) |
| "A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat." | 3.66 | Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979) |
| "Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response." | 3.65 | 6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977) |
| "Up to 8% of pregnant women suffer from preeclampsia (PE), a deadly disease characterized by high blood pressure (BP), blood vessel damage, called endotheliosis (vascular endothelial swelling with narrowing of capillary lumen), and high levels of protein in the urine." | 2.58 | Vitamin B ( Fushima, T; Ito, S; Li, F; Oe, Y; Oyanagi, G; Saigusa, D; Sato, E; Sato, H; Sekimoto, A; Takahashi, N, 2018) |
| "The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed." | 2.50 | A review of nicotinamide: treatment of skin diseases and potential side effects. ( Rolfe, HM, 2014) |
| " High-dose nicotinamide should still, however, be considered as a drug with toxic potential at adult doses in excess of 3 gm/day and unsupervised use should be discouraged." | 2.41 | Safety of high-dose nicotinamide: a review. ( Bingley, PJ; Douek, IF; Gale, EA; Gillmor, HA; Knip, M; McLean, AE; Moore, WP, 2000) |
| "It was recently reported in mice that miscarriage can be prevented through the administration of niacin." | 1.62 | Vitamin B3 levels in women who experience first-trimester miscarriage. ( Peek, MJ; Quinlivan, JA; Yakob, NA, 2021) |
| " Recently developed pharmacokinetic models could explain this phenomenon." | 1.39 | Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib. ( Beijnen, JH; de Vries, N; Schinkel, AH; Sparidans, RW; Tang, SC; Wagenaar, E, 2013) |
| "Pemphigoid gestationis is an autoimmune blistering disease of pregnancy caused by autoantibodies directed against BP180 (type XVII collagen) in the basement membrane zone." | 1.37 | Pemphigoid gestationis: current management. ( Intong, LR; Murrell, DF, 2011) |
| "Perinatal asphyxia was induced by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 16 or 20 min." | 1.34 | Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth. ( Bustamante, D; Goiny, M; Herrera-Marschitz, M; Morales, P; Pereyra, JT, 2007) |
| "Perinatal asphyxia was induced in vivo by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 20 min." | 1.34 | Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide. ( Bustamante, D; Gomez-Urquijo, S; Herrera-Marschitz, M; Hökfelt, T; Klawitter, V; Morales, P, 2007) |
| "Fetal hydrocephalus was induced by single intraperitoneal injection of 8 mg/kg 6-aminonicotinamide (6-AN), a niacinamide antagonist, in Sprague-Dawley rat on day 13 of gestation." | 1.28 | Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat. ( Matsumoto, S; Oi, S; Tamaki, N; Taomoto, K; Yamada, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 123 (68.33) | 18.7374 |
| 1990's | 9 (5.00) | 18.2507 |
| 2000's | 17 (9.44) | 29.6817 |
| 2010's | 23 (12.78) | 24.3611 |
| 2020's | 8 (4.44) | 2.80 |
| Authors | Studies |
|---|---|
| DeBoer, MD | 1 |
| Platts-Mills, JA | 1 |
| Elwood, SE | 1 |
| Scharf, RJ | 1 |
| McDermid, JM | 1 |
| Wanjuhi, AW | 1 |
| Jatosh, S | 1 |
| Katengu, S | 1 |
| Parpia, TC | 1 |
| Rogawski McQuade, ET | 1 |
| Gratz, J | 1 |
| Svensen, E | 1 |
| Swann, JR | 1 |
| Donowitz, JR | 1 |
| Mdoe, P | 1 |
| Kivuyo, S | 1 |
| Houpt, ER | 1 |
| Mduma, E | 1 |
| Liang, D | 1 |
| Batross, J | 1 |
| Fiedler, N | 1 |
| Prapamontol, T | 1 |
| Suttiwan, P | 1 |
| Panuwet, P | 1 |
| Naksen, W | 1 |
| Baumert, BO | 1 |
| Yakimavets, V | 1 |
| Tan, Y | 1 |
| D'Souza, P | 1 |
| Mangklabruks, A | 1 |
| Sittiwang, S | 1 |
| Kaewthit, K | 1 |
| Kohsuwan, K | 1 |
| Promkam, N | 1 |
| Pingwong, S | 1 |
| Ryan, PB | 1 |
| Barr, DB | 1 |
| Faingold, MC | 1 |
| Luquez, C | 1 |
| Oviedo, A | 1 |
| Puchulu, F | 1 |
| Re, M | 1 |
| Cuny, H | 1 |
| Bozon, K | 1 |
| Kirk, RB | 1 |
| Sheng, DZ | 1 |
| Bröer, S | 1 |
| Dunwoodie, SL | 1 |
| Lee, SR | 1 |
| Jeong, SH | 1 |
| Mukae, M | 1 |
| Kim, SY | 1 |
| Ko, JW | 1 |
| Kwun, HJ | 1 |
| Hong, EJ | 1 |
| Willyard, C | 1 |
| Yakob, NA | 1 |
| Peek, MJ | 1 |
| Quinlivan, JA | 1 |
| Brownfoot, F | 1 |
| Binder, N | 1 |
| Hastie, R | 1 |
| Harper, A | 1 |
| Beard, S | 1 |
| Tuohey, L | 1 |
| Keenan, E | 1 |
| Tong, S | 1 |
| Hannan, N | 1 |
| Takahashi, N | 4 |
| Li, F | 2 |
| Fushima, T | 4 |
| Oyanagi, G | 2 |
| Sato, E | 4 |
| Oe, Y | 4 |
| Sekimoto, A | 4 |
| Saigusa, D | 2 |
| Sato, H | 4 |
| Ito, S | 4 |
| Ear, PH | 1 |
| Chadda, A | 1 |
| Gumusoglu, SB | 1 |
| Schmidt, MS | 1 |
| Vogeler, S | 1 |
| Malicoat, J | 1 |
| Kadel, J | 1 |
| Moore, MM | 1 |
| Migaud, ME | 1 |
| Stevens, HE | 1 |
| Brenner, C | 1 |
| Snaidr, VA | 1 |
| Damian, DL | 1 |
| Halliday, GM | 1 |
| Imaruoka, K | 1 |
| Sugawara, J | 1 |
| Lee, JH | 3 |
| Zhang, J | 2 |
| Flores, L | 1 |
| Rose, JC | 1 |
| Massmann, GA | 2 |
| Figueroa, JP | 2 |
| Scheller, K | 1 |
| Röckl, T | 1 |
| Scheller, C | 1 |
| Schubert, J | 1 |
| Tang, SC | 1 |
| de Vries, N | 1 |
| Sparidans, RW | 1 |
| Wagenaar, E | 1 |
| Beijnen, JH | 1 |
| Schinkel, AH | 1 |
| Tian, YJ | 1 |
| Luo, N | 1 |
| Chen, NN | 1 |
| Lun, YZ | 1 |
| Gu, XY | 1 |
| Li, Z | 1 |
| Ma, Q | 1 |
| Zhou, SS | 1 |
| Rolfe, HM | 1 |
| Kinoshita, A | 1 |
| Kenéz, Á | 1 |
| Locher, L | 1 |
| Meyer, U | 1 |
| Dänicke, S | 1 |
| Rehage, J | 1 |
| Huber, K | 1 |
| El-Heis, S | 1 |
| Crozier, SR | 1 |
| Robinson, SM | 1 |
| Harvey, NC | 1 |
| Cooper, C | 1 |
| Inskip, HM | 1 |
| Godfrey, KM | 1 |
| Mahdi, AJ | 1 |
| Gosrani, D | 1 |
| Chakraborty, M | 1 |
| Rees, A | 1 |
| Conner, C | 1 |
| Wilson, K | 1 |
| Rayment, R | 1 |
| Alvares, C | 1 |
| Townley-Tilson, HW | 1 |
| Nakada, H | 1 |
| Hagaman, JR | 1 |
| Wilder, J | 1 |
| Li, M | 1 |
| Jennette, JC | 1 |
| Maeda, N | 1 |
| Karumanchi, SA | 1 |
| Smithies, O | 1 |
| Smedts, HP | 2 |
| Rakhshandehroo, M | 1 |
| Verkleij-Hagoort, AC | 1 |
| de Vries, JH | 2 |
| Ottenkamp, J | 1 |
| Steegers, EA | 2 |
| Steegers-Theunissen, RP | 2 |
| Michel, ME | 1 |
| Alanio, E | 1 |
| Bois, E | 1 |
| Gavillon, N | 1 |
| Graesslin, O | 1 |
| Szukiewicz, D | 2 |
| Szewczyk, G | 1 |
| Mittal, TK | 1 |
| Rongies, W | 2 |
| Maslinski, S | 1 |
| Pyzlak, M | 1 |
| Stangret, A | 1 |
| Maslinska, D | 1 |
| NEUWAHL, FJ | 1 |
| Wu, YJ | 1 |
| Zhu, YC | 1 |
| Chen, H | 1 |
| Huang, Y | 1 |
| Wei, Q | 1 |
| Chen, HJ | 1 |
| Xie, X | 1 |
| Li, X | 1 |
| Zhou, Q | 1 |
| Yang, YR | 1 |
| Zeng, H | 1 |
| Lappas, M | 1 |
| Permezel, M | 1 |
| Intong, LR | 1 |
| Murrell, DF | 1 |
| Bi, J | 1 |
| Li, H | 1 |
| Ye, SQ | 1 |
| Ding, S | 1 |
| John, CM | 1 |
| Ramasamy, R | 1 |
| Al Naqeeb, G | 1 |
| Al-Nuaimi, AH | 1 |
| Adam, A | 1 |
| Amato, L | 1 |
| Coronella, G | 1 |
| Berti, S | 1 |
| Gallerani, I | 1 |
| Moretti, S | 1 |
| Fabbri, P | 1 |
| Bustamante, D | 3 |
| Goiny, M | 2 |
| Aström, G | 1 |
| Gross, J | 1 |
| Andersson, K | 1 |
| Herrera-Marschitz, M | 3 |
| MARTELLI, G | 1 |
| CECCACCI, F | 1 |
| BARTOLOMEI, G | 1 |
| ROSSI, M | 1 |
| MISCHEL, W | 1 |
| SPITALI, R | 1 |
| QUADRI, G | 1 |
| COLAJACOMO, A | 1 |
| VALLERINO, V | 1 |
| CHIEFFI, O | 2 |
| COLOMBO, L | 1 |
| INGALLS, TH | 4 |
| INGENITO, EF | 2 |
| CURLEY, FJ | 3 |
| CHAMBERLAIN, JG | 8 |
| NELSON, MM | 1 |
| SMITHBERG, M | 1 |
| RUNNER, MN | 1 |
| FILSELL, OH | 1 |
| JARRETT, IG | 1 |
| ATKINSON, MR | 1 |
| CAIGER, P | 1 |
| MORTON, RK | 1 |
| MANGIAROTTI, MA | 1 |
| FELISATI, D | 1 |
| BERNARDINIJARAMILLO, E | 1 |
| FRATTA, I | 2 |
| ZAK, SB | 2 |
| GREENGARD, P | 2 |
| SIGG, EB | 2 |
| HUANG, PC | 1 |
| LIU, DK | 1 |
| KAO, MS | 1 |
| GOLDSTEIN, M | 1 |
| FRASER, FC | 7 |
| ROTH, K | 1 |
| HAGERMAN, DD | 1 |
| VILLEE, CA | 1 |
| ROUX, JF | 1 |
| GORDON, EE | 1 |
| BAKER, H | 2 |
| PINSKY, L | 1 |
| Ftukijwatari, T | 1 |
| Murakami, M | 1 |
| Ohta, M | 1 |
| Kimura, N | 1 |
| Jin-No, Y | 1 |
| Sasaki, R | 1 |
| Shibata, K | 2 |
| Bruno, EJ | 1 |
| Ziegenfuss, TN | 1 |
| Parimala, K | 1 |
| Peedicayil, J | 1 |
| Peedicayil, A | 1 |
| Nelson, N | 1 |
| Ernest, K | 1 |
| Ieraci, A | 1 |
| Herrera, DG | 1 |
| Hofmann, SC | 1 |
| Bruckner-Tuderman, L | 1 |
| Spong, CY | 1 |
| Das, UN | 1 |
| Morales, P | 2 |
| Pereyra, JT | 1 |
| Klawitter, V | 1 |
| Gomez-Urquijo, S | 1 |
| Hökfelt, T | 1 |
| Skyler, JS | 1 |
| van Driel, LM | 1 |
| Helbing, WA | 1 |
| Isaacs, A | 1 |
| Lindemans, J | 1 |
| Uitterlinden, AG | 1 |
| van Duijn, CM | 1 |
| Smithells, RW | 1 |
| Sheppard, S | 1 |
| Schorah, CJ | 1 |
| Seller, MJ | 1 |
| Nevin, NC | 1 |
| Harris, R | 1 |
| Read, AP | 1 |
| Fielding, DW | 1 |
| Rolig, EC | 1 |
| Hook, JB | 2 |
| Bond, JT | 1 |
| Tanaka, H | 1 |
| Nakazawa, K | 1 |
| Suzuki, N | 1 |
| Arima, M | 1 |
| Kröger, H | 1 |
| Grätz, R | 1 |
| Trasler, DG | 4 |
| Ohannessian, L | 1 |
| Zakirov, IZ | 1 |
| Adizov, IuSh | 1 |
| Yochim, JM | 1 |
| Tseng, CY | 2 |
| Ling, EA | 2 |
| Wong, WC | 2 |
| Sotelo, C | 1 |
| Rio, JP | 1 |
| Horwitt, MK | 1 |
| Harper, AE | 1 |
| Henderson, LM | 1 |
| McCandless, DW | 1 |
| Scott, WJ | 3 |
| Spector, R | 1 |
| Huntoon, S | 1 |
| Andersen, HU | 1 |
| Larsen, PM | 1 |
| Fey, SJ | 1 |
| Karlsen, AE | 1 |
| Mandrup-Poulsen, T | 1 |
| Nerup, J | 1 |
| Campbell, JM | 1 |
| Murphy, MR | 1 |
| Christensen, RA | 1 |
| Overton, TR | 1 |
| Tsai, FC | 1 |
| Gardner, DK | 1 |
| Beattie, GM | 1 |
| Rubin, JS | 1 |
| Mally, MI | 1 |
| Otonkoski, T | 1 |
| Hayek, A | 1 |
| Aoyagi, K | 1 |
| Bergsten, P | 1 |
| Eriksson, UJ | 1 |
| Ebendal, T | 1 |
| Hellerström, C | 2 |
| Toda, S | 1 |
| McKiernan, SH | 1 |
| Bavister, BD | 1 |
| Knip, M | 1 |
| Douek, IF | 1 |
| Moore, WP | 1 |
| Gillmor, HA | 1 |
| McLean, AE | 1 |
| Bingley, PJ | 1 |
| Gale, EA | 1 |
| Loo, WJ | 1 |
| Dean, D | 1 |
| Wojnarowska, F | 1 |
| Claycomb, WC | 1 |
| Klinger, W | 1 |
| Muller, D | 1 |
| Clark, BR | 1 |
| Halpern, RM | 1 |
| Smith, RA | 1 |
| Ritter, EJ | 2 |
| Wilson, JG | 2 |
| Briggs, RM | 1 |
| Seinsch, W | 1 |
| Krowke, R | 1 |
| Berg, P | 1 |
| Merker, HJ | 6 |
| Schoental, R | 1 |
| Scheil, HG | 2 |
| Claussen, U | 2 |
| Grote, W | 8 |
| Biddle, FG | 1 |
| Rearden, CA | 1 |
| Rajchgot, H | 1 |
| Diewert, VM | 1 |
| Beaudoin, AR | 1 |
| Lorimer, WS | 1 |
| Stone, PR | 1 |
| Kidwell, WR | 1 |
| Yamada, H | 1 |
| Oi, S | 1 |
| Tamaki, N | 1 |
| Matsumoto, S | 1 |
| Taomoto, K | 1 |
| Blomquist, CH | 1 |
| Hakanson, EY | 1 |
| Jaster, EH | 1 |
| Ward, NE | 1 |
| Sandler, S | 1 |
| Andersson, A | 1 |
| Korsgren, O | 1 |
| Tollemar, J | 1 |
| Petersson, B | 1 |
| Groth, CG | 1 |
| Suh, BH | 1 |
| Cho, YH | 1 |
| Gotoh, H | 1 |
| Nomura, T | 1 |
| Nakajima, H | 1 |
| Hasegawa, C | 1 |
| Sakamoto, Y | 1 |
| Karolyi, J | 1 |
| Erickson, RP | 1 |
| Liu, S | 1 |
| Horner, JL | 1 |
| Windle, LM | 1 |
| Coppock, CE | 1 |
| Labore, JM | 1 |
| Lanham, JK | 1 |
| Nave, DH | 1 |
| Kuwahara, M | 1 |
| Chaykin, S | 1 |
| Myers, GS | 1 |
| Petrakis, NL | 1 |
| Lee, M | 1 |
| Careddu, P | 1 |
| Marini, A | 1 |
| Lojkin, ME | 2 |
| Schardein, JL | 1 |
| Woosley, ET | 1 |
| Peltzer, MA | 1 |
| Kaump, DH | 1 |
| Metcalf, WK | 1 |
| Gershbein, LL | 1 |
| Nogami, H | 2 |
| Verrusio, AC | 1 |
| Pollard, DR | 3 |
| Zappasodi, P | 1 |
| Fernández, NA | 1 |
| Burgos, JC | 1 |
| Roberts, LJ | 1 |
| Asenjo, CF | 1 |
| Turbow, MM | 2 |
| Yamane, H | 1 |
| Kato, T | 1 |
| Grillo, G | 1 |
| Luvarà, A | 1 |
| Rovere, F | 1 |
| Gebhardt, DO | 2 |
| Koroleva, AM | 1 |
| Grigor'eva, EG | 1 |
| Borzov, VA | 1 |
| Schade, GJ | 1 |
| Brown, RR | 2 |
| Rose, DP | 2 |
| Price, JM | 2 |
| Wolf, H | 2 |
| Funayama, Y | 1 |
| Yamashita, H | 1 |
| Hirsch, GH | 1 |
| Neubert, D | 2 |
| Woodard, JC | 1 |
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| Barrach, HJ | 1 |
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| Zimmermann, B | 1 |
| Clark, WH | 1 |
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| Kasahara, M | 2 |
| Lyons, WR | 1 |
| Knopp, K | 1 |
| Landauer, W | 1 |
| Kabarity, A | 1 |
| Wilson, JT | 1 |
| Waterman, R | 1 |
| Schultz, LH | 1 |
| Hambraeus, L | 1 |
| Ganich, MM | 2 |
| Long, SY | 1 |
| Larsson, KS | 1 |
| Lohmander, S | 1 |
| Zens, P | 1 |
| Rothenwallner, A | 1 |
| Sudeck, M | 3 |
| Shih, LY | 1 |
| Chiancone, FM | 1 |
| Mainardi, L | 1 |
| Tenconi, LT | 1 |
| Tarachand, U | 1 |
| Eapen, J | 1 |
| Korabel'shchikova, NI | 1 |
| Aĭzenberg NN+AIZENBERG, NN | 1 |
| Lesik, OV | 1 |
| Kaminetzky, HA | 1 |
| Frank, O | 1 |
| Langer, A | 1 |
| Pinder, S | 2 |
| Greenbaum, AL | 2 |
| Fratta, ID | 1 |
| Courtney, KD | 1 |
| Valerio, DA | 1 |
| Braidman, IP | 1 |
| Heinz, D | 1 |
| Juchau, MR | 1 |
| Krasner, J | 1 |
| Yaffe, SJ | 1 |
| Abdel-Aziz, A | 1 |
| Karrar, MA | 1 |
| Scharfschwerdt, H | 1 |
| Schulz, W | 1 |
| Rapoport, S | 1 |
| Macome, JC | 1 |
| Bischoff, K | 1 |
| Bai, RU | 1 |
| Diczfalusy, E | 1 |
| Schweichel, JU | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Life Interventions for Childhood Growth and Development In Tanzania[NCT03268902] | Phase 2/Phase 3 | 1,188 participants (Actual) | Interventional | 2017-09-05 | Completed | ||
| Three-Day Dosing NAD + Study[NCT03707652] | 8 participants (Actual) | Interventional | 2018-03-12 | Completed | |||
| Randomized Double-blinded Comparative Trial to Study the Add-on Activity of Combination Treatment of Nicotinamide on Progression Free Survival for EGFR Mutated Lung Cancer Terminal Stage Patients Being Treated With Gefitinib or Erlotinib[NCT02416739] | Phase 2/Phase 3 | 110 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | ||
| A Study of the Pharmacology of 17-Hydroxyprogesterone Caproate in Pregnancy[NCT00409825] | Phase 2 | 61 participants (Actual) | Interventional | 2006-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Change in the area under the concentration vs. time curve in the second and third trimesters of pregnancy.~We compared AUC at each PK study visit. Measurements were obtained at 0, 1, 2, 3, 4, 5, 6, 7 days." (NCT00409825)
Timeframe: Second and third trimesters of pregnancy
| Intervention | ng/ML/day (Mean) | |
|---|---|---|
| AUC -1 | AUC - 2 | |
| Part 1 | 115 | 136 |
11 reviews available for niacinamide and Pregnancy
| Article | Year |
|---|---|
Vitamin B
Topics: Animals; Disease Models, Animal; Female; Fetal Development; Humans; Niacinamide; Pre-Eclampsia; Preg | 2018 |
Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Chemoprevention; Dermatology; DNA Damage; | 2019 |
A review of nicotinamide: treatment of skin diseases and potential side effects.
Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Chemical and Drug Induced Liver Inju | 2014 |
Water-soluble vitamins: research update.
Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural T | 2005 |
Prediction and prevention of type 1 diabetes: progress, problems, and prospects.
Topics: Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Female; Forecasting; Humans; Hypoglycemic Agents; I | 2007 |
Niacin-tryptophan relationships for evaluating niacin equivalents.
Topics: Biological Availability; Child; Dietary Proteins; Female; Food Analysis; Food Labeling; Humans; Infa | 1981 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites.
Topics: Adult; Amides; Amines; Chromatography, Ion Exchange; Equipment and Supplies; Female; Hormones; Human | 1965 |
Is insulin a teratogen?
Topics: Abnormalities, Drug-Induced; Animals; Beak; Brain; Chick Embryo; Congenital Abnormalities; Drug Inte | 1972 |
Developmental pharmacology: a review of its application to clinical and basic science.
Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental; | 1972 |
Excretion of tryptophan metabolites as affected by pregnancy, contraceptive steroids, and steroid hormones.
Topics: Androsterone; Animals; Contraceptives, Oral; Enzyme Induction; Estradiol; Female; Humans; Hydrocorti | 1971 |
3 trials available for niacinamide and Pregnancy
| Article | Year |
|---|---|
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial.
Topics: Adult; Anti-Infective Agents; Azithromycin; Child Development; Double-Blind Method; Drug Administrat | 2021 |
Possible prevention of neural-tube defects by periconceptional vitamin supplementation.
Topics: Abortion, Spontaneous; Ascorbic Acid; Avitaminosis; Clinical Trials as Topic; Drug Combinations; Fem | 1980 |
Kinetics of niacin supplements in lactating dairy cows.
Topics: Animal Feed; Animals; Body Fluids; Cattle; Digestion; Drug Stability; Duodenum; Female; Fermentation | 1994 |
166 other studies available for niacinamide and Pregnancy
| Article | Year |
|---|---|
Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers.
Topics: Biomarkers; Child; Chlorpyrifos; Creatinine; Cystine; Cytochromes; Farmers; Fatty Acids; Female; Glu | 2022 |
[Pharmacological and clinical characteristics of Insulin Faster Aspart (Fiasp®)].
Topics: Aged; Blood Glucose; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; Hypoglyc | 2022 |
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice.
Topics: Amino Acid Transport Systems, Neutral; Animals; Congenital Abnormalities; Female; Heterozygote; Kidn | 2023 |
Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia.
Topics: Animals; Dietary Supplements; Female; Fetal Development; Humans; Hyperglycemia; Hypoglycemia; Hypogl | 2023 |
How gut microbes could drive brain disorders.
Topics: alpha-Synuclein; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autism Spectrum Disorder | 2021 |
Vitamin B3 levels in women who experience first-trimester miscarriage.
Topics: Abortion, Spontaneous; Animals; Female; Humans; Mice; Niacin; Niacinamide; Pilot Projects; Pregnancy | 2021 |
Nicotinamide and its effects on endothelial dysfunction and secretion of antiangiogenic factors by primary human placental cells and tissues.
Topics: Angiogenesis Inhibitors; Blood Vessels; Cells, Cultured; Endothelium, Vascular; Female; Human Umbili | 2021 |
Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring.
Topics: Animals; Female; Lactation; Liver; Maternal Exposure; Mice; NAD; Neurogenesis; Niacinamide; Postpart | 2019 |
Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide.
Topics: Animals; Disease Models, Animal; Female; Glomerulonephritis; Lipopolysaccharides; Lupus Erythematosu | 2019 |
Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Blood Pressure; Dantrolene; Dose-Response Relation | 2013 |
Lower concentrations of B-vitamin subgroups in the serum and amniotic fluid correlate to cleft lip and palate appearance in the offspring of A/WySn mice.
Topics: Adenine; Alkaline Phosphatase; Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cleft | 2013 |
Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Trans | 2013 |
Maternal nicotinamide supplementation causes global DNA hypomethylation, uracil hypo-incorporation and gene expression changes in fetal rats.
Topics: Animals; Betaine; Brain; Dietary Supplements; DNA; DNA Methylation; Down-Regulation; Epigenesis, Gen | 2014 |
Antenatal betamethasone increases vascular reactivity to endothelin-1 by upregulation of CD38/cADPR signaling.
Topics: ADP-ribosyl Cyclase 1; Animals; Betamethasone; Blood Pressure; Cyclic ADP-Ribose; Endothelin-1; Fema | 2014 |
Insulin Signaling in Liver and Adipose Tissues in Periparturient Dairy Cows Supplemented with Dietary Nicotinic Acid.
Topics: Adipose Tissue; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Cat | 2016 |
Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months.
Topics: Adult; Age Factors; Biomarkers; Comorbidity; Dermatitis, Atopic; Female; Humans; Infant; Kynurenine; | 2016 |
Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; Humans; Leukemia, Myeloi | 2018 |
Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
Topics: Abortion, Spontaneous; Albuminuria; Animals; Animals, Newborn; Blood Pressure; Body Weight; Disease | 2016 |
Nicotinamide ameliorates a preeclampsia-like condition in mice with reduced uterine perfusion pressure.
Topics: Animals; Blood Pressure; Embryonic Development; Female; Fetal Growth Retardation; Mice; Niacinamide; | 2017 |
Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects.
Topics: Adult; Case-Control Studies; Dietary Fats; Female; Heart Defects, Congenital; Humans; Infant, Newbor | 2008 |
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Niacinamid | 2010 |
Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells.
Topics: Adult; Amniotic Fluid; C-Peptide; Cell Differentiation; Cells, Cultured; Cimetidine; Epithelial Cell | 2010 |
Decrease in expression of histamine H2 receptors by human amniotic epithelial cells during differentiation into pancreatic beta-like cells.
Topics: Amnion; C-Peptide; Cell Differentiation; Cell Shape; Cells, Cultured; Epithelial Cells; Female; Huma | 2010 |
Nicotinamide and diabetes mellitus.
Topics: Diabetes Mellitus; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnancy | 1947 |
Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus during pregnancy response to sorafenib.
Topics: Adult; Antineoplastic Agents; Benzenesulfonates; Female; Humans; Kidney Neoplasms; Neuroectodermal T | 2010 |
The anti-inflammatory and antioxidative effects of nicotinamide, a vitamin B(3) derivative, are elicited by FoxO3 in human gestational tissues: implications for preterm birth.
Topics: Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Female; Forkhead Box Protein O3; Forkhead | 2011 |
Pemphigoid gestationis: current management.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Azathioprine | 2011 |
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.
Topics: Acrylamides; Animals; Brain; Cell Death; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Fem | 2012 |
Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses.
Topics: Animals; Blood Glucose; Catalase; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes, Ges | 2012 |
Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis.
Topics: Adult; Anti-Bacterial Agents; Doxycycline; Female; Humans; Niacinamide; Pemphigoid, Bullous; Pregnan | 2002 |
Nicotinamide prevents the long-term effects of perinatal asphyxia on basal ganglia monoamine systems in the rat.
Topics: Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Biogenic Monoamines; Cesarean Section; Female; N | 2003 |
[Clinical studies on the effect of vitamin PP in labor].
Topics: Biomedical Research; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnan | 1952 |
[Liver function test in pregnancy; effect of trigonellamide (N1-methylnicotinamide chloride) on pyruvic, lactic, and amino acids in the blood in liver insufficiency in pregnancy].
Topics: Amino Acids; Chlorides; Hepatic Insufficiency; Liver Function Tests; Niacin; Niacinamide; Nicotinic | 1953 |
[Biogenic amines of the placenta. III. Nicotinic acid and nicotinamide content of mature, immature, normal and pathological human placenta].
Topics: Biogenic Amines; Female; Humans; Niacin; Niacinamide; Nicotinic Acids; Placenta; Pregnancy | 1957 |
[Effect of nicotinamide on the pyridine coenzyme content of the rat placenta].
Topics: Animals; Coenzymes; Female; Niacin; Niacinamide; Placenta; Pregnancy; Pyridines; Rats | 1963 |
[DPN-DPNH, TPN-TPNH and pyridine compound content in the liver of the pregnant rat and fetus and in the placenta after large doses of nicotinamide].
Topics: Animals; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; NAD; NADP; Niacin; Niacinamide; Plac | 1963 |
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY INJECTION OF A TERATOGEN IN PREGNANCY.
Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Female; Humans; Injections; Mice; Niac | 1963 |
CONGENITAL ABNORMALITIES IN THE RAT RESULTING FROM SINGLE INJECTIONS OF 6-AMINONICOTINAMIDE DURING PREGNANCY.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Antimetabolites; Brain; Cardiovascular Sy | 1963 |
TERATOGENIC EFFECTS OF HYPOGLYCEMIC TREATMENTS IN INBRED STRAINS OF MICE.
Topics: Abnormalities, Drug-Induced; Animals; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred Strains; Niac | 1963 |
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY KNOWN TERATOGEN.
Topics: Alloxan; Animals; Chromosome Aberrations; Cleft Palate; Embryo, Mammalian; Embryo, Nonmammalian; Fem | 1964 |
NICOTINAMIDE NUCLEOTIDE COENZYMES AND GLUCOSE METABOLISM IN THE LIVERS OF FOETAL AND NEWBORN LAMBS.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Body Weight; Carbohydrate Metabolism; Coenzymes; | 1963 |
[METABOLISM OF GLUCOSE AND FRUCTOSE IN THE HUMAN PLACENTA].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbohydrate Metabolism; Female; Fructose; Glucose; NAD | 1963 |
TERATOGENIC ACTION OF THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Female; Folic Acid; Glutamine; Niacinamide; Pregnancy; Pregnancy Compli | 1964 |
[INFLUENCE OF VITAMIN PP IN THE PROCESS OF ODONTOGENESIS].
Topics: Animals; Animals, Newborn; Bone and Bones; Calcification, Physiologic; Dental Calculus; Dental Carie | 1963 |
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Topics: Animals; Avitaminosis; Chlorpromazine; Diet; Female; Fetal Death; Fetus; Imipramine; Liver; NAD; Nia | 1964 |
THE METABOLISM OF ALPHA-N-MONOMETHYL-L-TRYPTOPHAN (L-ABRIN) IN MAN AND IN NORMAL AND PYRIDOXINE DEFICIENT RATS.
Topics: Abrin; Amino Acids; Body Fluids; Eclampsia; Female; Humans; Kynurenine; Male; Niacin; Niacinamide; P | 1964 |
RESISTANCE OF A-JAX MOUSE EMBRYOS WITH SPONTANEOUS CONGENITAL CLEFT LIP TO THE LETHAL EFFECT OF 6-AMINO-NICOTINAMIDE.
Topics: Animals; Cleft Lip; Female; Genetics; Humans; Mice; Niacinamide; Pregnancy; Research; Toxicology | 1965 |
KINETICS OF NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENATION BY HUMAN PLACENTA.
Topics: Biochemical Phenomena; Biochemistry; Catalysis; Estradiol; Estrone; Female; Humans; Kinetics; NAD; N | 1965 |
CONTENT AND SYNTHESIS OF HEPATIC PYRIDINE NUCLEOTIDES IN FETAL AND NEONATAL RABBITS.
Topics: Aging; Animals; DNA; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Metabolism; NAD; NADP; N | 1965 |
Congenital malformations after a two-hour inactivation of nicotinamide in pregnant mice.
Topics: Animals; Congenital Abnormalities; Mice; Niacin; Niacinamide; Nicotinic Acids; Pregnancy | 1960 |
Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Female; Gestational Age; Humans; Niacin; Niacin | 2004 |
The effect of a nicorandil congener on isolated human myometrium.
Topics: Adult; Area Under Curve; Dysmenorrhea; Female; Humans; Middle Aged; Myometrium; Niacinamide; Obstetr | 2006 |
Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain.
Topics: Animals; Apoptosis; Brain; Central Nervous System Depressants; Ethanol; Female; Fetal Alcohol Spectr | 2006 |
[Bullous pemphigoid: diagnostics and new therapeutic strategies].
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy | 2006 |
Protection against prenatal alcohol-induced damage.
Topics: Adult; Animals; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Female; Fetal A | 2006 |
Fetal alcohol syndrome and essential fatty acids.
Topics: Animals; Central Nervous System Depressants; Ethanol; Fatty Acids, Essential; Female; Fetal Alcohol | 2006 |
Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth.
Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Central Nervous System Stimu | 2007 |
Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide.
Topics: Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Cell Count; Disease Models | 2007 |
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
Topics: Adult; Child; Drug-Related Side Effects and Adverse Reactions; Epidemiologic Methods; Female; Geneti | 2008 |
In vitro renal transport functions of the progeny of rats with streptozotocin-induced diabetes.
Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport; Diabetes Mellitus, Experimental; Female | 1982 |
Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia.
Topics: Animals; Brain; Carbonic Anhydrases; Central Nervous System Diseases; Ethanol; Female; Fetal Alcohol | 1982 |
[Effect of L-tryptophan, nicotinamide, L-methionine and 1-methylnicotinamide on the embryotoxic effect of various substances].
Topics: 6-Aminonicotinamide; Animals; Cyclophosphamide; Drug Interactions; Embryo, Mammalian; Female; Hydrox | 1983 |
Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip.
Topics: 6-Aminonicotinamide; Animals; Cell Fusion; Cleft Lip; Embryo, Mammalian; Female; Mice; Mice, Inbred | 1983 |
[Efficacy of using coamid to treat viral hepatitis in pregnant women].
Topics: Cobalt; Female; Hepatitis, Viral, Human; Humans; Male; Niacinamide; Organometallic Compounds; Pregna | 1984 |
Modulation of uterine sensitivity to decidual induction in the rat by nicotinamide; challenge and extension of a model of progestational differentiation.
Topics: Animals; Decidua; Embryo Implantation; Female; NAD; NADP; Niacinamide; Pregnancy; Progesterone; Rats | 1984 |
A scanning and transmission electron microscopic study of amoeboid microglial cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Animals; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Microsco | 1984 |
Cerebellar malformation obtained in rats by early postnatal treatment with 6-aminonicotinamide. Role of neuron-glia interactions in cerebellar development.
Topics: 6-Aminonicotinamide; Animals; Cell Movement; Cerebellar Cortex; Cerebellum; Dendrites; Female; Micro | 1980 |
The effect of 6-aminonicotinamide on energy metabolism in rat embryo neural tube.
Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Brain; Central Nervous System; Embryo, Mammali | 1981 |
No effect of maternal niacin deficiency on niacin metabolism in newborn brain.
Topics: Animals; Animals, Newborn; Brain; Cerebellum; Female; In Vitro Techniques; Kinetics; Maternal-Fetal | 1981 |
Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide.
Topics: Animals; Arginine; Electrophoresis, Gel, Two-Dimensional; Female; Interleukin-1; Islets of Langerhan | 1995 |
Nicotinamide, a component of complex culture media, inhibits mouse embryo development in vitro and reduces subsequent developmental potential after transfer.
Topics: Animals; Blastocyst; Cleavage Stage, Ovum; Culture Media; Culture Techniques; Embryo Transfer; Embry | 1994 |
Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.
Topics: Abortion, Induced; Animals; C-Peptide; Cell Aggregation; Cell Communication; Cell Differentiation; C | 1996 |
In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16.
Topics: Animals; Cells, Cultured; Female; Gestational Age; Glucose; Insulin; Insulin Secretion; Islets of La | 1997 |
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Horm | 1997 |
Culture of one-cell hamster embryos with water soluble vitamins: pantothenate stimulates blastocyst production.
Topics: Animals; Blastocyst; Choline; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relations | 2000 |
A severe persistent case of recurrent pemphigoid gestationis successfully treated with minocycline and nicotinamide.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Immunosuppressive Agents; Minocycline; Niacinamide; Pe | 2001 |
Inhibition of DNA synthesis in differentiating cardiac muscle by NAD.
Topics: Animals; Animals, Newborn; Biological Transport, Active; Cell Differentiation; DNA Replication; Fema | 1976 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochro | 1976 |
A fluorimetric method for quantitation in the picomole range of N1-methylnicotinamide and nicotinamide in serum.
Topics: Female; Humans; Hypercholesterolemia; Kinetics; Male; Microchemistry; Niacinamide; Pregnancy; Pregna | 1975 |
Inhibition of ATP synthesis associated with 6-aminonicotinamide (6-AN) teratogenesis in rat embryos.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Dinitrophenols; F | 1975 |
Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans.
Topics: Ascorbic Acid; Calcium; Cleft Lip; Cleft Palate; Female; Folic Acid; Humans; Infant, Newborn; Matern | 1976 |
[Embryonic development of hypophysis, adrenal glands and gonads in rat embryos after 6-aminonicotinamide administration].
Topics: 6-Aminonicotinamide; Adrenal Glands; Animals; Endoplasmic Reticulum; Female; Gonads; Maternal-Fetal | 1976 |
Effects of cytosine arabinoside, 6-aminonicotinamide, and 6-mercaptopurine riboside on ectoderm and mesoderm of mouse limb buds.
Topics: 6-Aminonicotinamide; Animals; Cytarabine; DNA; Ectoderm; Embryo, Mammalian; Extremities; Female; Glu | 1977 |
The role of nicotinamide and of certain other modifying factors in diethylnitrosamine carcinogenesis: fusaria mycotoxins and "spontaneous" tumors in animals and man.
Topics: Animals; Diethylnitrosamine; Female; Fusarium; Gastrointestinal Neoplasms; Genital Neoplasms, Female | 1977 |
Effect of 6-aminonicotinamide in teratogenic doses on the DNA- and RNA-concentration in rabbit embryos.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; DNA; Dose-Response Relationship, Drug; Em | 1977 |
6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship, | 1977 |
A selection experiment for distinct types of 6-aminonicotinamide-induced cleft lip in mice.
Topics: 6-Aminonicotinamide; Animals; Cleft Lip; Crosses, Genetic; Face; Female; Genotype; Male; Mice; Mice, | 1978 |
Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship, | 1979 |
NAD precursors as antiteratogens against aminothiadiazole.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Resorption; Gestational Age; Kynurenine; Ma | 1976 |
Control of histone H1 dimer-poly(ADP-ribose) complex formation by poly(ADP-ribose) glycohydrolase.
Topics: Animals; Breast Neoplasms; Cell Line; Cell Nucleus; Female; Glycoside Hydrolases; Histones; Humans; | 1977 |
Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Brain; Dandy-Walker Syndrome; Disease Mod | 1991 |
Pyridine nucleotide levels under conditions of 5 alpha-dihydrotestosterone-stimulated 17 beta-estradiol formation from estrone and pathway of nicotinamide adenine dinucleotide biosynthesis in placental villi in vitro.
Topics: Chorionic Villi; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Kinetics; NAD; NADP; Niaci | 1991 |
Supplemental nicotinic acid or nicotinamide for lactating dairy cows.
Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood Glucose; Body Weight; Cattle; Eating; Fatty Acids | 1990 |
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
Topics: Culture Techniques; Female; Glucose; Humans; Insulin; Islets of Langerhans; Niacinamide; Pancreas; P | 1989 |
A comparative study on the NAD glycohydrolase of the maternal and neonatal erythrocytes.
Topics: Enzyme Activation; Erythrocytes; Female; Fetal Blood; Humans; Infant, Newborn; N-Glycosyl Hydrolases | 1985 |
An electron microscopical study of epiplexus and supraependymal cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Animals; Cerebral Ventricles; Choroid Plexus; Ependyma; Female; Hydrocephalus; | 1985 |
Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Fem | 1988 |
Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Male; Mice; Mice, I | 1988 |
Effects of whole cottonseed, niacin, and niacinamide on in vitro rumen fermentation and on lactating Holstein cows.
Topics: Animals; Cattle; Cottonseed Oil; Female; Fermentation; In Vitro Techniques; Lactation; Niacin; Niaci | 1988 |
Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus).
Topics: Animals; Azaserine; Carbon Isotopes; Chorionic Gonadotropin; Embryo Implantation; Embryo, Mammalian; | 1973 |
Effect of 6-aminonicotinamide and of added vitamin A on fusion of embryonic rat palates in vitro.
Topics: Animals; Autoradiography; Cleft Palate; Culture Media; Female; In Vitro Techniques; Maternal-Fetal E | 1967 |
Stimulating bilirubin conjugation.
Topics: Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Niacinamide; Pregnancy; | 1968 |
Effect of levels of nitrogen intake on tryptophan metabolism and requirement for pregnancy of the rat.
Topics: Animals; Female; Glutamates; Glycine; Male; Niacinamide; Nitrogen; Nucleotides; Pregnancy; Pregnancy | 1967 |
Effects of acute vitamin replacement therapy on 6-aminonicotinamide induced cleft palate late in rat pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy; | 1967 |
Congenital malformations induced by 6-aminonicotinamide in rabbit kits.
Topics: Abnormalities, Drug-Induced; Animals; Eye Abnormalities; Female; Niacinamide; Pregnancy; Pregnancy, | 1967 |
Development of cleft palate induced by 6-aminonicotinamide late in rat gestation.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy; | 1966 |
Failure of steroid hormones to reverse the toxic effects of 6-aminonicotinamide given early in pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Estrone; Female; Fetal Death; Mice; Niacinami | 1967 |
The relation of vitamin-B complex to the effect of thalidomide on the sensitivity of intracellular haemoglobin to oxidation.
Topics: Animals; Erythrocytes; Female; Glutethimide; Hemoglobins; Male; Niacinamide; Oxidation-Reduction; Ph | 1967 |
Effect of transplanted tumor and various agents on liver regeneration during pregnancy.
Topics: Animals; Benzofurans; Carcinoma 256, Walker; Female; Fetal Death; Hepatectomy; Liver Regeneration; N | 1966 |
Pathogenesis of spinal malformations induced in the embryos of mice.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Lumbar Vertebrae; Mice; Niacinamide | 1967 |
A cytoplasmically transmitted, diet-dependent difference in response to the teratogenic effects of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Diet; Extrachromosomal Inheritance; Female; Hybr | 1968 |
6-aminonicotinamide-induced skeletal malformations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Bone and Bones; Cleft Palate; Female; Fetal D | 1968 |
Nutritional status in Puerto Rican slum area.
Topics: Adolescent; Adult; Aged; Anthropometry; Child; Child, Preschool; Deficiency Diseases; Diet; Erythroc | 1968 |
Direct effects of 6-aminonicotinamide on the developing rat embryo in vitro and in vivo.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Antimetabolites; Cleft Palate; Culture Media; Culture | 1968 |
[Experimental studies on the development of malformations of the extremities. 2. On the process of the development of tibia defects].
Topics: Abnormalities, Drug-Induced; Animals; Female; Maternal-Fetal Exchange; Mice; Niacinamide; Pregnancy; | 1968 |
[Metoclopramide does not influence urinary elimination of N-methylnicotinamide and 5-OH-indoleacetic acid].
Topics: Adult; Amides; Benzoates; Female; Humans; Indoleacetic Acids; Injections, Intramuscular; Nausea; Nia | 1968 |
The effects of starvation or of treatment with cytotoxic agents on pregnancy in mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dactinomycin; Embryo, Mammalian; Embryonic | 1969 |
[Use of hemotransfusion in the complex therapy of anemias during hypotonic hemorrhages in labor].
Topics: Anemia, Hypochromic; Ascorbic Acid; Blood Transfusion; Female; Hematopoiesis; Humans; Iron; Niacinam | 1969 |
Is there an optimal stage for the induction of cleft palate in the mouse?
Topics: Animals; Cleft Palate; Cyclophosphamide; Dexamethasone; Female; Mice; Niacinamide; Pregnancy; Pregna | 1969 |
Tryptophan metabolism as affected by anovulatory agents.
Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kyn | 1969 |
[Clinical and experimental studies of delta phalanx of the hallux].
Topics: Abnormalities, Drug-Induced; Animals; Child; Child, Preschool; Female; Hallux; Humans; Infant, Newbo | 1969 |
Stimulation of renal organic acid transport and protein synthesis by penicillin.
Topics: Aminohippuric Acids; Ammonium Chloride; Animals; Biological Transport, Active; Body Fluids; Body Wei | 1970 |
Variations in drug metabolism during mammalian development genetic aspects.
Topics: Animals; Biotransformation; Embryo, Mammalian; Enzyme Induction; Female; Fetus; Genetic Variation; M | 1970 |
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Developme | 1970 |
[Disturbances of tooth development in rat embryos following administration of 6-aminonicotinamide].
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Incisor; Microscopy, Electron; Niac | 1970 |
Further studies on a cytoplasmically transmitted difference in response to the teratogen 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Diet; Extrachromosomal Inheritance; F | 1968 |
Biochemical studies of the embryotoxic action of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Acetates; Aspartic Acid; Carbon Isotopes; DNA; Embryo, Mammalian; Embry | 1970 |
Electron microscope studies on the effect of 6-aminonicotinamide on mammalian embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Culture Techniques; Ectoderm; Embryo, Mammalian; Female | 1970 |
Embryonic abnormalities in hamsters following intrauterine injection of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Anophthalmos; Brain; Cleft Palate; Cricetinae; | 1971 |
The effects of intraamniotic injection of dexamethasone in rats.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Cleft Palate; Dexamethasone; Drug Synergism; Ext | 1971 |
Influence of maternal age and parity on fetal mortality and congenital abnormalities induced in rats.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Eye Abnormalities; Female; Feta | 1971 |
[Ambulatory therapy of pregnancy toxicoses].
Topics: Ambulatory Care; Ascorbic Acid; Female; Fetus; Folic Acid; Humans; Niacinamide; Pre-Eclampsia; Pregn | 1970 |
[Disturbed embryonic mitosis in rabbits after administration of 6-aminonicotinic acid amide].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Embryo, Mammalian; Female; Fibroblasts; Liver; Mitosis | 1972 |
[Experiments on the induction and prevention of malformations in rabbits].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Animals, Newborn; Antimetabolites; Cell Division; Cong | 1972 |
Nicotinic acid loading of normal cows: effects on blood metabolites and excretory forms.
Topics: Administration, Oral; Animals; Blood Glucose; Cattle; Diuresis; Fatty Acids, Nonesterified; Female; | 1972 |
[Vitamins. 9. Niacin].
Topics: Adult; Ascorbic Acid Deficiency; Developing Countries; Diet; Female; Food; Humans; Infant; Infant Nu | 1972 |
6-Aminonicotinamide (6-AN)-induced abnormalities of the developing ependyma and choroid plexus as seen with the scanning electron microscope.
Topics: Abnormalities, Drug-Induced; Animals; Cell Membrane; Choroid Plexus; Cilia; Ependyma; Female; Fetus; | 1972 |
[Vitamins C, PP and B-6 in the blood and placenta in the developmental dynamics of pregnancy and labor normally and in obstetrical pathology].
Topics: Ascorbic Acid; Blood Chemical Analysis; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Lab | 1973 |
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; F | 1973 |
Cell proliferation in the cranial base of A-J mice with 6-AN-induced cleft palate.
Topics: Animals; Autoradiography; Cartilage; Cell Division; Cleft Lip; Cleft Palate; Female; Fetus; Gestatio | 1973 |
A survey of the embryotoxic effects of TCDD in mammalian species.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Amines; Animals; Cleft Palate; Cyclo | 1973 |
[Preliminary teratological experiments with mini-pigs ("Göttinger miniaturschwein") (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; Gestational Age; Niacinamide; | 1973 |
[Experimental studies on the boundary sensitive phase of embryonal development of "Göttingen miniature pigs"].
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Embryonic and Fetal Developm | 1973 |
Relation of mandible growth to palate closure in mice.
Topics: Amines; Animals; Body Weight; Cleft Palate; Cortisone; Female; Gestational Age; Mandible; Maxillofac | 1974 |
[Tryptophan metabolism in screening metabolic diseases of the newborn].
Topics: Amino Acid Metabolism, Inborn Errors; Evaluation Studies as Topic; Female; Humans; Infant, Newborn; | 1973 |
[Phase-specific pattern of malformation in the Goettinger miniature pig following administration of 6-amino-nicotinamide].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Female; Fetus; Injections, Intraperitonea | 1974 |
[Vitamins C, PP and B6 in the blood and placenta in the dynamics of the development of pregnancy and labor normally and in obstetrical pathology].
Topics: Ascorbic Acid; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Labor Complications; Placent | 1973 |
The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway.
Topics: Adolescent; Adult; Aged; Androgens; Animals; Estrogens; Female; Humans; Hydrocortisone; Hydrolases; | 1974 |
[Effect of 6-aminonicotinic acid amide in teratogenic dosis on the ATP-concentration in rabbit embryos].
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Amines; Animals; Embryo, Mammalian; Female; Nia | 1974 |
Effect of streptozotocin-diabetes on in vivo protein synthesis by placenta and liver of mice.
Topics: Animals; Blood Glucose; Body Weight; Carbon Radioisotopes; Diabetes Mellitus; Female; Insulin; Leuci | 1974 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; | 1974 |
The effects of intravenously administered water-soluble vitamins during labor in normovitaminemic and hypovitaminemic gravidas on maternal and neonatal blood vitamin levels at delivery.
Topics: Adolescent; Adult; Ascorbic Acid; Avitaminosis; Biotin; Female; Folic Acid; Humans; Infant, Newborn; | 1974 |
Reduction of 6-aminonicotinamide teratogenicity in mice by etherization.
Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Animals; Cleft Lip; Ether; Ethyl Ethers; Female | 1970 |
Induction of a cytoplasmic factor increasing resistance to the teratogenic effect of 6-aminonicotinamide in mice.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Enzyme Induction | 1973 |
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Deficiency Diseases; Desoxycorticosterone; Dex | 1966 |
The pathway of synthesis of mammary-gland nicotinamide-adenine dinucleotide.
Topics: Animals; Female; Lactation; Liver; Mammary Glands, Animal; NAD; Niacinamide; Pregnancy; Rats | 1967 |
The pathway of biosynthesis of nicotinamide-adenine dinucleotide in rat mammary gland.
Topics: Animals; Female; Glucosyltransferases; Kinetics; Lactation; Mammary Glands, Animal; Models, Biologic | 1968 |
Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures.
Topics: Amino Acids; Animals; Deficiency Diseases; Diet; Dietary Proteins; Feces; Female; Fetal Death; Fetus | 1970 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
Teratology in the Macaca mulatta.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Clomiphene; Encephalocele; Female; Fetal Death; Haplo | 1968 |
[Induction and prevention of developmental abnormalities in rabbits by administration of 6-aminonicotinic acid and nicotinic acid amide].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Female; Fetus; Gestational Age; Microphthalmos; Mouth | 1971 |
Studies on reduction of azo-linkages in human placental homogenates.
Topics: Azo Compounds; Carbon Monoxide; Edetic Acid; Female; Flavins; Glucosephosphate Dehydrogenase; Glutat | 1968 |
Effect of some beta-pyridyl derivatives and of histamine on the rat uterus under different functional states.
Topics: Animals; Estrus; Ethanolamines; Female; Histamine; Histamine H1 Antagonists; Kymography; Methanol; N | 1969 |
[The stabilization of glucose-6-phosphate dehydrogenase in the rat mammary gland].
Topics: Animals; Female; Glucosephosphate Dehydrogenase; Glutathione; Hexosephosphates; In Vitro Techniques; | 1969 |
Factors influencing placental steroidogenesis.
Topics: 17-Ketosteroids; Adenosine Triphosphate; Androstenes; Animals; Carbon Isotopes; Cholesterol; Chorion | 1972 |
The morphology of various types of cell death in prenatal tissues.
Topics: Abnormalities, Drug-Induced; Animals; Cell Survival; Cyclophosphamide; Dactinomycin; Embryo, Mammali | 1973 |