niacinamide has been researched along with Pregnancy in 180 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
---|---|---|
" Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy." | 7.72 | Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004) |
"In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections." | 7.67 | Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988) |
"A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)." | 7.66 | Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983) |
"A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat." | 7.66 | Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979) |
"Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response." | 7.65 | 6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977) |
" Maternal serum levels of kynurenine, kynurenic acid, anthranilic acid, tryptophan, nicotinamide and N1-methylnicotinamide were measured in late pregnancy by mass spectrometry (n = 497) and related to the odds ratio of infantile atopic eczema." | 3.83 | Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. ( Cooper, C; Crozier, SR; El-Heis, S; Godfrey, KM; Harvey, NC; Inskip, HM; Robinson, SM, 2016) |
" Therefore, experimental studies including tryptophan metabolism studies could provide insight into niacin nutrition in pregnancy." | 3.72 | Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats. ( Ftukijwatari, T; Jin-No, Y; Kimura, N; Murakami, M; Ohta, M; Sasaki, R; Shibata, K, 2004) |
"It is known that deaths attributable to pellagra, which is considered to be a disease caused by the disturbance of tryptophan metabolism, have been approximately two-fold higher in women than in men." | 3.69 | Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats. ( Shibata, K; Toda, S, 1997) |
"In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections." | 3.67 | Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. ( Erickson, RP; Karolyi, J; Liu, S, 1988) |
" During pregnancy, some of both groups received zinc or nicotinamide-adenine dinucleotide (NAD) or nicotinamide throughout pregnancy and glucose for gestational day (gd) 15 to 19 with E or W." | 3.66 | Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia. ( Arima, M; Nakazawa, K; Suzuki, N; Tanaka, H, 1982) |
"A search was made for cell ultrastructure differences in the initial fusion process of the medial and lateral nasal processes in mouse embryos of the following types: A/J with 12% cleft lip (CL), CL/Fr with 23% CL--both cleft-lip-predisposed strains, CL/Fr 6-aminonicotinamide (6AN)-treated (94% CL) and controls from the C57BL/6 strain (0% CL) and dancer stock (0% CL)." | 3.66 | Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip. ( Ohannessian, L; Trasler, DG, 1983) |
"A single injection of the niacin antimetabolite 6-aminonicotinamide (6-AN) late in gestation produces cleft palate in the rat." | 3.66 | Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat. ( Diewert, VM, 1979) |
"Cleft palate induction by 6-aminonicotinamide (6-AN) was examined in the A/J and C57BL/6J strains of mice to determine the nature of the strain difference in frequency of cleft-palate response." | 3.65 | 6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis. ( Biddle, FG, 1977) |
"Up to 8% of pregnant women suffer from preeclampsia (PE), a deadly disease characterized by high blood pressure (BP), blood vessel damage, called endotheliosis (vascular endothelial swelling with narrowing of capillary lumen), and high levels of protein in the urine." | 2.58 | Vitamin B ( Fushima, T; Ito, S; Li, F; Oe, Y; Oyanagi, G; Saigusa, D; Sato, E; Sato, H; Sekimoto, A; Takahashi, N, 2018) |
"The use of topical nicotinamide in the treatment of acne vulgaris; melasma; atopic dermatitis; rosacea; and oral nicotinamide in preventing nonmelanoma skin cancer is discussed." | 2.50 | A review of nicotinamide: treatment of skin diseases and potential side effects. ( Rolfe, HM, 2014) |
" High-dose nicotinamide should still, however, be considered as a drug with toxic potential at adult doses in excess of 3 gm/day and unsupervised use should be discouraged." | 2.41 | Safety of high-dose nicotinamide: a review. ( Bingley, PJ; Douek, IF; Gale, EA; Gillmor, HA; Knip, M; McLean, AE; Moore, WP, 2000) |
"It was recently reported in mice that miscarriage can be prevented through the administration of niacin." | 1.62 | Vitamin B3 levels in women who experience first-trimester miscarriage. ( Peek, MJ; Quinlivan, JA; Yakob, NA, 2021) |
" Recently developed pharmacokinetic models could explain this phenomenon." | 1.39 | Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib. ( Beijnen, JH; de Vries, N; Schinkel, AH; Sparidans, RW; Tang, SC; Wagenaar, E, 2013) |
"Pemphigoid gestationis is an autoimmune blistering disease of pregnancy caused by autoantibodies directed against BP180 (type XVII collagen) in the basement membrane zone." | 1.37 | Pemphigoid gestationis: current management. ( Intong, LR; Murrell, DF, 2011) |
"Perinatal asphyxia was induced by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 16 or 20 min." | 1.34 | Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth. ( Bustamante, D; Goiny, M; Herrera-Marschitz, M; Morales, P; Pereyra, JT, 2007) |
"Perinatal asphyxia was induced in vivo by immersing foetuses-containing uterine horns removed from ready-to-deliver rats into a water bath for 20 min." | 1.34 | Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide. ( Bustamante, D; Gomez-Urquijo, S; Herrera-Marschitz, M; Hökfelt, T; Klawitter, V; Morales, P, 2007) |
"Fetal hydrocephalus was induced by single intraperitoneal injection of 8 mg/kg 6-aminonicotinamide (6-AN), a niacinamide antagonist, in Sprague-Dawley rat on day 13 of gestation." | 1.28 | Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat. ( Matsumoto, S; Oi, S; Tamaki, N; Taomoto, K; Yamada, H, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 123 (68.33) | 18.7374 |
1990's | 9 (5.00) | 18.2507 |
2000's | 17 (9.44) | 29.6817 |
2010's | 23 (12.78) | 24.3611 |
2020's | 8 (4.44) | 2.80 |
Authors | Studies |
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DeBoer, MD | 1 |
Platts-Mills, JA | 1 |
Elwood, SE | 1 |
Scharf, RJ | 1 |
McDermid, JM | 1 |
Wanjuhi, AW | 1 |
Jatosh, S | 1 |
Katengu, S | 1 |
Parpia, TC | 1 |
Rogawski McQuade, ET | 1 |
Gratz, J | 1 |
Svensen, E | 1 |
Swann, JR | 1 |
Donowitz, JR | 1 |
Mdoe, P | 1 |
Kivuyo, S | 1 |
Houpt, ER | 1 |
Mduma, E | 1 |
Liang, D | 1 |
Batross, J | 1 |
Fiedler, N | 1 |
Prapamontol, T | 1 |
Suttiwan, P | 1 |
Panuwet, P | 1 |
Naksen, W | 1 |
Baumert, BO | 1 |
Yakimavets, V | 1 |
Tan, Y | 1 |
D'Souza, P | 1 |
Mangklabruks, A | 1 |
Sittiwang, S | 1 |
Kaewthit, K | 1 |
Kohsuwan, K | 1 |
Promkam, N | 1 |
Pingwong, S | 1 |
Ryan, PB | 1 |
Barr, DB | 1 |
Faingold, MC | 1 |
Luquez, C | 1 |
Oviedo, A | 1 |
Puchulu, F | 1 |
Re, M | 1 |
Cuny, H | 1 |
Bozon, K | 1 |
Kirk, RB | 1 |
Sheng, DZ | 1 |
Bröer, S | 1 |
Dunwoodie, SL | 1 |
Lee, SR | 1 |
Jeong, SH | 1 |
Mukae, M | 1 |
Kim, SY | 1 |
Ko, JW | 1 |
Kwun, HJ | 1 |
Hong, EJ | 1 |
Willyard, C | 1 |
Yakob, NA | 1 |
Peek, MJ | 1 |
Quinlivan, JA | 1 |
Brownfoot, F | 1 |
Binder, N | 1 |
Hastie, R | 1 |
Harper, A | 1 |
Beard, S | 1 |
Tuohey, L | 1 |
Keenan, E | 1 |
Tong, S | 1 |
Hannan, N | 1 |
Takahashi, N | 4 |
Li, F | 2 |
Fushima, T | 4 |
Oyanagi, G | 2 |
Sato, E | 4 |
Oe, Y | 4 |
Sekimoto, A | 4 |
Saigusa, D | 2 |
Sato, H | 4 |
Ito, S | 4 |
Ear, PH | 1 |
Chadda, A | 1 |
Gumusoglu, SB | 1 |
Schmidt, MS | 1 |
Vogeler, S | 1 |
Malicoat, J | 1 |
Kadel, J | 1 |
Moore, MM | 1 |
Migaud, ME | 1 |
Stevens, HE | 1 |
Brenner, C | 1 |
Snaidr, VA | 1 |
Damian, DL | 1 |
Halliday, GM | 1 |
Imaruoka, K | 1 |
Sugawara, J | 1 |
Lee, JH | 3 |
Zhang, J | 2 |
Flores, L | 1 |
Rose, JC | 1 |
Massmann, GA | 2 |
Figueroa, JP | 2 |
Scheller, K | 1 |
Röckl, T | 1 |
Scheller, C | 1 |
Schubert, J | 1 |
Tang, SC | 1 |
de Vries, N | 1 |
Sparidans, RW | 1 |
Wagenaar, E | 1 |
Beijnen, JH | 1 |
Schinkel, AH | 1 |
Tian, YJ | 1 |
Luo, N | 1 |
Chen, NN | 1 |
Lun, YZ | 1 |
Gu, XY | 1 |
Li, Z | 1 |
Ma, Q | 1 |
Zhou, SS | 1 |
Rolfe, HM | 1 |
Kinoshita, A | 1 |
Kenéz, Á | 1 |
Locher, L | 1 |
Meyer, U | 1 |
Dänicke, S | 1 |
Rehage, J | 1 |
Huber, K | 1 |
El-Heis, S | 1 |
Crozier, SR | 1 |
Robinson, SM | 1 |
Harvey, NC | 1 |
Cooper, C | 1 |
Inskip, HM | 1 |
Godfrey, KM | 1 |
Mahdi, AJ | 1 |
Gosrani, D | 1 |
Chakraborty, M | 1 |
Rees, A | 1 |
Conner, C | 1 |
Wilson, K | 1 |
Rayment, R | 1 |
Alvares, C | 1 |
Townley-Tilson, HW | 1 |
Nakada, H | 1 |
Hagaman, JR | 1 |
Wilder, J | 1 |
Li, M | 1 |
Jennette, JC | 1 |
Maeda, N | 1 |
Karumanchi, SA | 1 |
Smithies, O | 1 |
Smedts, HP | 2 |
Rakhshandehroo, M | 1 |
Verkleij-Hagoort, AC | 1 |
de Vries, JH | 2 |
Ottenkamp, J | 1 |
Steegers, EA | 2 |
Steegers-Theunissen, RP | 2 |
Michel, ME | 1 |
Alanio, E | 1 |
Bois, E | 1 |
Gavillon, N | 1 |
Graesslin, O | 1 |
Szukiewicz, D | 2 |
Szewczyk, G | 1 |
Mittal, TK | 1 |
Rongies, W | 2 |
Maslinski, S | 1 |
Pyzlak, M | 1 |
Stangret, A | 1 |
Maslinska, D | 1 |
NEUWAHL, FJ | 1 |
Wu, YJ | 1 |
Zhu, YC | 1 |
Chen, H | 1 |
Huang, Y | 1 |
Wei, Q | 1 |
Chen, HJ | 1 |
Xie, X | 1 |
Li, X | 1 |
Zhou, Q | 1 |
Yang, YR | 1 |
Zeng, H | 1 |
Lappas, M | 1 |
Permezel, M | 1 |
Intong, LR | 1 |
Murrell, DF | 1 |
Bi, J | 1 |
Li, H | 1 |
Ye, SQ | 1 |
Ding, S | 1 |
John, CM | 1 |
Ramasamy, R | 1 |
Al Naqeeb, G | 1 |
Al-Nuaimi, AH | 1 |
Adam, A | 1 |
Amato, L | 1 |
Coronella, G | 1 |
Berti, S | 1 |
Gallerani, I | 1 |
Moretti, S | 1 |
Fabbri, P | 1 |
Bustamante, D | 3 |
Goiny, M | 2 |
Aström, G | 1 |
Gross, J | 1 |
Andersson, K | 1 |
Herrera-Marschitz, M | 3 |
MARTELLI, G | 1 |
CECCACCI, F | 1 |
BARTOLOMEI, G | 1 |
ROSSI, M | 1 |
MISCHEL, W | 1 |
SPITALI, R | 1 |
QUADRI, G | 1 |
COLAJACOMO, A | 1 |
VALLERINO, V | 1 |
CHIEFFI, O | 2 |
COLOMBO, L | 1 |
INGALLS, TH | 4 |
INGENITO, EF | 2 |
CURLEY, FJ | 3 |
CHAMBERLAIN, JG | 8 |
NELSON, MM | 1 |
SMITHBERG, M | 1 |
RUNNER, MN | 1 |
FILSELL, OH | 1 |
JARRETT, IG | 1 |
ATKINSON, MR | 1 |
CAIGER, P | 1 |
MORTON, RK | 1 |
MANGIAROTTI, MA | 1 |
FELISATI, D | 1 |
BERNARDINIJARAMILLO, E | 1 |
FRATTA, I | 2 |
ZAK, SB | 2 |
GREENGARD, P | 2 |
SIGG, EB | 2 |
HUANG, PC | 1 |
LIU, DK | 1 |
KAO, MS | 1 |
GOLDSTEIN, M | 1 |
FRASER, FC | 7 |
ROTH, K | 1 |
HAGERMAN, DD | 1 |
VILLEE, CA | 1 |
ROUX, JF | 1 |
GORDON, EE | 1 |
BAKER, H | 2 |
PINSKY, L | 1 |
Ftukijwatari, T | 1 |
Murakami, M | 1 |
Ohta, M | 1 |
Kimura, N | 1 |
Jin-No, Y | 1 |
Sasaki, R | 1 |
Shibata, K | 2 |
Bruno, EJ | 1 |
Ziegenfuss, TN | 1 |
Parimala, K | 1 |
Peedicayil, J | 1 |
Peedicayil, A | 1 |
Nelson, N | 1 |
Ernest, K | 1 |
Ieraci, A | 1 |
Herrera, DG | 1 |
Hofmann, SC | 1 |
Bruckner-Tuderman, L | 1 |
Spong, CY | 1 |
Das, UN | 1 |
Morales, P | 2 |
Pereyra, JT | 1 |
Klawitter, V | 1 |
Gomez-Urquijo, S | 1 |
Hökfelt, T | 1 |
Skyler, JS | 1 |
van Driel, LM | 1 |
Helbing, WA | 1 |
Isaacs, A | 1 |
Lindemans, J | 1 |
Uitterlinden, AG | 1 |
van Duijn, CM | 1 |
Smithells, RW | 1 |
Sheppard, S | 1 |
Schorah, CJ | 1 |
Seller, MJ | 1 |
Nevin, NC | 1 |
Harris, R | 1 |
Read, AP | 1 |
Fielding, DW | 1 |
Rolig, EC | 1 |
Hook, JB | 2 |
Bond, JT | 1 |
Tanaka, H | 1 |
Nakazawa, K | 1 |
Suzuki, N | 1 |
Arima, M | 1 |
Kröger, H | 1 |
Grätz, R | 1 |
Trasler, DG | 4 |
Ohannessian, L | 1 |
Zakirov, IZ | 1 |
Adizov, IuSh | 1 |
Yochim, JM | 1 |
Tseng, CY | 2 |
Ling, EA | 2 |
Wong, WC | 2 |
Sotelo, C | 1 |
Rio, JP | 1 |
Horwitt, MK | 1 |
Harper, AE | 1 |
Henderson, LM | 1 |
McCandless, DW | 1 |
Scott, WJ | 3 |
Spector, R | 1 |
Huntoon, S | 1 |
Andersen, HU | 1 |
Larsen, PM | 1 |
Fey, SJ | 1 |
Karlsen, AE | 1 |
Mandrup-Poulsen, T | 1 |
Nerup, J | 1 |
Campbell, JM | 1 |
Murphy, MR | 1 |
Christensen, RA | 1 |
Overton, TR | 1 |
Tsai, FC | 1 |
Gardner, DK | 1 |
Beattie, GM | 1 |
Rubin, JS | 1 |
Mally, MI | 1 |
Otonkoski, T | 1 |
Hayek, A | 1 |
Aoyagi, K | 1 |
Bergsten, P | 1 |
Eriksson, UJ | 1 |
Ebendal, T | 1 |
Hellerström, C | 2 |
Toda, S | 1 |
McKiernan, SH | 1 |
Bavister, BD | 1 |
Knip, M | 1 |
Douek, IF | 1 |
Moore, WP | 1 |
Gillmor, HA | 1 |
McLean, AE | 1 |
Bingley, PJ | 1 |
Gale, EA | 1 |
Loo, WJ | 1 |
Dean, D | 1 |
Wojnarowska, F | 1 |
Claycomb, WC | 1 |
Klinger, W | 1 |
Muller, D | 1 |
Clark, BR | 1 |
Halpern, RM | 1 |
Smith, RA | 1 |
Ritter, EJ | 2 |
Wilson, JG | 2 |
Briggs, RM | 1 |
Seinsch, W | 1 |
Krowke, R | 1 |
Berg, P | 1 |
Merker, HJ | 6 |
Schoental, R | 1 |
Scheil, HG | 2 |
Claussen, U | 2 |
Grote, W | 8 |
Biddle, FG | 1 |
Rearden, CA | 1 |
Rajchgot, H | 1 |
Diewert, VM | 1 |
Beaudoin, AR | 1 |
Lorimer, WS | 1 |
Stone, PR | 1 |
Kidwell, WR | 1 |
Yamada, H | 1 |
Oi, S | 1 |
Tamaki, N | 1 |
Matsumoto, S | 1 |
Taomoto, K | 1 |
Blomquist, CH | 1 |
Hakanson, EY | 1 |
Jaster, EH | 1 |
Ward, NE | 1 |
Sandler, S | 1 |
Andersson, A | 1 |
Korsgren, O | 1 |
Tollemar, J | 1 |
Petersson, B | 1 |
Groth, CG | 1 |
Suh, BH | 1 |
Cho, YH | 1 |
Gotoh, H | 1 |
Nomura, T | 1 |
Nakajima, H | 1 |
Hasegawa, C | 1 |
Sakamoto, Y | 1 |
Karolyi, J | 1 |
Erickson, RP | 1 |
Liu, S | 1 |
Horner, JL | 1 |
Windle, LM | 1 |
Coppock, CE | 1 |
Labore, JM | 1 |
Lanham, JK | 1 |
Nave, DH | 1 |
Kuwahara, M | 1 |
Chaykin, S | 1 |
Myers, GS | 1 |
Petrakis, NL | 1 |
Lee, M | 1 |
Careddu, P | 1 |
Marini, A | 1 |
Lojkin, ME | 2 |
Schardein, JL | 1 |
Woosley, ET | 1 |
Peltzer, MA | 1 |
Kaump, DH | 1 |
Metcalf, WK | 1 |
Gershbein, LL | 1 |
Nogami, H | 2 |
Verrusio, AC | 1 |
Pollard, DR | 3 |
Zappasodi, P | 1 |
Fernández, NA | 1 |
Burgos, JC | 1 |
Roberts, LJ | 1 |
Asenjo, CF | 1 |
Turbow, MM | 2 |
Yamane, H | 1 |
Kato, T | 1 |
Grillo, G | 1 |
Luvarà, A | 1 |
Rovere, F | 1 |
Gebhardt, DO | 2 |
Koroleva, AM | 1 |
Grigor'eva, EG | 1 |
Borzov, VA | 1 |
Schade, GJ | 1 |
Brown, RR | 2 |
Rose, DP | 2 |
Price, JM | 2 |
Wolf, H | 2 |
Funayama, Y | 1 |
Yamashita, H | 1 |
Hirsch, GH | 1 |
Neubert, D | 2 |
Woodard, JC | 1 |
Novák, L | 1 |
Yess, N | 1 |
Barrach, HJ | 1 |
Köhler, E | 1 |
Novack, L | 1 |
Zimmermann, B | 1 |
Clark, WH | 1 |
Dipaolo, JA | 1 |
Kasahara, M | 2 |
Lyons, WR | 1 |
Knopp, K | 1 |
Landauer, W | 1 |
Kabarity, A | 1 |
Wilson, JT | 1 |
Waterman, R | 1 |
Schultz, LH | 1 |
Hambraeus, L | 1 |
Ganich, MM | 2 |
Long, SY | 1 |
Larsson, KS | 1 |
Lohmander, S | 1 |
Zens, P | 1 |
Rothenwallner, A | 1 |
Sudeck, M | 3 |
Shih, LY | 1 |
Chiancone, FM | 1 |
Mainardi, L | 1 |
Tenconi, LT | 1 |
Tarachand, U | 1 |
Eapen, J | 1 |
Korabel'shchikova, NI | 1 |
Aĭzenberg NN+AIZENBERG, NN | 1 |
Lesik, OV | 1 |
Kaminetzky, HA | 1 |
Frank, O | 1 |
Langer, A | 1 |
Pinder, S | 2 |
Greenbaum, AL | 2 |
Fratta, ID | 1 |
Courtney, KD | 1 |
Valerio, DA | 1 |
Braidman, IP | 1 |
Heinz, D | 1 |
Juchau, MR | 1 |
Krasner, J | 1 |
Yaffe, SJ | 1 |
Abdel-Aziz, A | 1 |
Karrar, MA | 1 |
Scharfschwerdt, H | 1 |
Schulz, W | 1 |
Rapoport, S | 1 |
Macome, JC | 1 |
Bischoff, K | 1 |
Bai, RU | 1 |
Diczfalusy, E | 1 |
Schweichel, JU | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Early Life Interventions for Childhood Growth and Development In Tanzania[NCT03268902] | Phase 2/Phase 3 | 1,188 participants (Actual) | Interventional | 2017-09-05 | Completed | ||
Three-Day Dosing NAD + Study[NCT03707652] | 8 participants (Actual) | Interventional | 2018-03-12 | Completed | |||
Randomized Double-blinded Comparative Trial to Study the Add-on Activity of Combination Treatment of Nicotinamide on Progression Free Survival for EGFR Mutated Lung Cancer Terminal Stage Patients Being Treated With Gefitinib or Erlotinib[NCT02416739] | Phase 2/Phase 3 | 110 participants (Actual) | Interventional | 2015-03-31 | Active, not recruiting | ||
A Study of the Pharmacology of 17-Hydroxyprogesterone Caproate in Pregnancy[NCT00409825] | Phase 2 | 61 participants (Actual) | Interventional | 2006-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Change in the area under the concentration vs. time curve in the second and third trimesters of pregnancy.~We compared AUC at each PK study visit. Measurements were obtained at 0, 1, 2, 3, 4, 5, 6, 7 days." (NCT00409825)
Timeframe: Second and third trimesters of pregnancy
Intervention | ng/ML/day (Mean) | |
---|---|---|
AUC -1 | AUC - 2 | |
Part 1 | 115 | 136 |
11 reviews available for niacinamide and Pregnancy
Article | Year |
---|---|
Vitamin B
Topics: Animals; Disease Models, Animal; Female; Fetal Development; Humans; Niacinamide; Pre-Eclampsia; Preg | 2018 |
Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Chemoprevention; Dermatology; DNA Damage; | 2019 |
A review of nicotinamide: treatment of skin diseases and potential side effects.
Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Chemical and Drug Induced Liver Inju | 2014 |
Water-soluble vitamins: research update.
Topics: Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Neural T | 2005 |
Prediction and prevention of type 1 diabetes: progress, problems, and prospects.
Topics: Diabetes Mellitus, Type 1; Fatty Acids, Omega-3; Female; Forecasting; Humans; Hypoglycemic Agents; I | 2007 |
Niacin-tryptophan relationships for evaluating niacin equivalents.
Topics: Biological Availability; Child; Dietary Proteins; Female; Food Analysis; Food Labeling; Humans; Infa | 1981 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Safety of high-dose nicotinamide: a review.
Topics: Abnormalities, Drug-Induced; Adenoma, Islet Cell; Animals; Chemical and Drug Induced Liver Injury; D | 2000 |
Testing the functional capacity of the tryptophan-niacin pathway in man by analysis of urinary metabolites.
Topics: Adult; Amides; Amines; Chromatography, Ion Exchange; Equipment and Supplies; Female; Hormones; Human | 1965 |
Is insulin a teratogen?
Topics: Abnormalities, Drug-Induced; Animals; Beak; Brain; Chick Embryo; Congenital Abnormalities; Drug Inte | 1972 |
Developmental pharmacology: a review of its application to clinical and basic science.
Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental; | 1972 |
Excretion of tryptophan metabolites as affected by pregnancy, contraceptive steroids, and steroid hormones.
Topics: Androsterone; Animals; Contraceptives, Oral; Enzyme Induction; Estradiol; Female; Humans; Hydrocorti | 1971 |
3 trials available for niacinamide and Pregnancy
Article | Year |
---|---|
Effect of scheduled antimicrobial and nicotinamide treatment on linear growth in children in rural Tanzania: A factorial randomized, double-blind, placebo-controlled trial.
Topics: Adult; Anti-Infective Agents; Azithromycin; Child Development; Double-Blind Method; Drug Administrat | 2021 |
Possible prevention of neural-tube defects by periconceptional vitamin supplementation.
Topics: Abortion, Spontaneous; Ascorbic Acid; Avitaminosis; Clinical Trials as Topic; Drug Combinations; Fem | 1980 |
Kinetics of niacin supplements in lactating dairy cows.
Topics: Animal Feed; Animals; Body Fluids; Cattle; Digestion; Drug Stability; Duodenum; Female; Fermentation | 1994 |
166 other studies available for niacinamide and Pregnancy
Article | Year |
---|---|
Metabolome-wide association study of the relationship between chlorpyrifos exposure and first trimester serum metabolite levels in pregnant Thai farmworkers.
Topics: Biomarkers; Child; Chlorpyrifos; Creatinine; Cystine; Cytochromes; Farmers; Fatty Acids; Female; Glu | 2022 |
[Pharmacological and clinical characteristics of Insulin Faster Aspart (Fiasp®)].
Topics: Aged; Blood Glucose; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Female; Humans; Hypoglyc | 2022 |
Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice.
Topics: Amino Acid Transport Systems, Neutral; Animals; Congenital Abnormalities; Female; Heterozygote; Kidn | 2023 |
Dietary supplementation with nicotinamide riboside improves fetal growth under hypoglycemia.
Topics: Animals; Dietary Supplements; Female; Fetal Development; Humans; Hyperglycemia; Hypoglycemia; Hypogl | 2023 |
How gut microbes could drive brain disorders.
Topics: alpha-Synuclein; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Autism Spectrum Disorder | 2021 |
Vitamin B3 levels in women who experience first-trimester miscarriage.
Topics: Abortion, Spontaneous; Animals; Female; Humans; Mice; Niacin; Niacinamide; Pilot Projects; Pregnancy | 2021 |
Nicotinamide and its effects on endothelial dysfunction and secretion of antiangiogenic factors by primary human placental cells and tissues.
Topics: Angiogenesis Inhibitors; Blood Vessels; Cells, Cultured; Endothelium, Vascular; Female; Human Umbili | 2021 |
Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring.
Topics: Animals; Female; Lactation; Liver; Maternal Exposure; Mice; NAD; Neurogenesis; Niacinamide; Postpart | 2019 |
Nicotinamide alleviates kidney injury and pregnancy outcomes in lupus-prone MRL/lpr mice treated with lipopolysaccharide.
Topics: Animals; Disease Models, Animal; Female; Glomerulonephritis; Lipopolysaccharides; Lupus Erythematosu | 2019 |
Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep.
Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Blood Pressure; Dantrolene; Dose-Response Relation | 2013 |
Lower concentrations of B-vitamin subgroups in the serum and amniotic fluid correlate to cleft lip and palate appearance in the offspring of A/WySn mice.
Topics: Adenine; Alkaline Phosphatase; Amniotic Fluid; Animals; Chromatography, High Pressure Liquid; Cleft | 2013 |
Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) gene dosage on plasma pharmacokinetics and brain accumulation of dasatinib, sorafenib, and sunitinib.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Trans | 2013 |
Maternal nicotinamide supplementation causes global DNA hypomethylation, uracil hypo-incorporation and gene expression changes in fetal rats.
Topics: Animals; Betaine; Brain; Dietary Supplements; DNA; DNA Methylation; Down-Regulation; Epigenesis, Gen | 2014 |
Antenatal betamethasone increases vascular reactivity to endothelin-1 by upregulation of CD38/cADPR signaling.
Topics: ADP-ribosyl Cyclase 1; Animals; Betamethasone; Blood Pressure; Cyclic ADP-Ribose; Endothelin-1; Fema | 2014 |
Insulin Signaling in Liver and Adipose Tissues in Periparturient Dairy Cows Supplemented with Dietary Nicotinic Acid.
Topics: Adipose Tissue; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Cat | 2016 |
Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months.
Topics: Adult; Age Factors; Biomarkers; Comorbidity; Dermatitis, Atopic; Female; Humans; Infant; Kynurenine; | 2016 |
Successful molecular targeted treatment of AML in pregnancy with Azacitidine and Sorafenib with no adverse fetal outcomes.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; Humans; Leukemia, Myeloi | 2018 |
Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia.
Topics: Abortion, Spontaneous; Albuminuria; Animals; Animals, Newborn; Blood Pressure; Body Weight; Disease | 2016 |
Nicotinamide ameliorates a preeclampsia-like condition in mice with reduced uterine perfusion pressure.
Topics: Animals; Blood Pressure; Embryonic Development; Female; Fetal Growth Retardation; Mice; Niacinamide; | 2017 |
Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects.
Topics: Adult; Case-Control Studies; Dietary Fats; Female; Heart Defects, Congenital; Humans; Infant, Newbor | 2008 |
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Niacinamid | 2010 |
Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells.
Topics: Adult; Amniotic Fluid; C-Peptide; Cell Differentiation; Cells, Cultured; Cimetidine; Epithelial Cell | 2010 |
Decrease in expression of histamine H2 receptors by human amniotic epithelial cells during differentiation into pancreatic beta-like cells.
Topics: Amnion; C-Peptide; Cell Differentiation; Cell Shape; Cells, Cultured; Epithelial Cells; Female; Huma | 2010 |
Nicotinamide and diabetes mellitus.
Topics: Diabetes Mellitus; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnancy | 1947 |
Primitive neuroectodermal tumor of the kidney with inferior vena cava tumor thrombus during pregnancy response to sorafenib.
Topics: Adult; Antineoplastic Agents; Benzenesulfonates; Female; Humans; Kidney Neoplasms; Neuroectodermal T | 2010 |
The anti-inflammatory and antioxidative effects of nicotinamide, a vitamin B(3) derivative, are elicited by FoxO3 in human gestational tissues: implications for preterm birth.
Topics: Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Female; Forkhead Box Protein O3; Forkhead | 2011 |
Pemphigoid gestationis: current management.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Azathioprine | 2011 |
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.
Topics: Acrylamides; Animals; Brain; Cell Death; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Fem | 2012 |
Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses.
Topics: Animals; Blood Glucose; Catalase; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes, Ges | 2012 |
Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis.
Topics: Adult; Anti-Bacterial Agents; Doxycycline; Female; Humans; Niacinamide; Pemphigoid, Bullous; Pregnan | 2002 |
Nicotinamide prevents the long-term effects of perinatal asphyxia on basal ganglia monoamine systems in the rat.
Topics: Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Biogenic Monoamines; Cesarean Section; Female; N | 2003 |
[Clinical studies on the effect of vitamin PP in labor].
Topics: Biomedical Research; Female; Humans; Labor, Obstetric; Niacin; Niacinamide; Nicotinic Acids; Pregnan | 1952 |
[Liver function test in pregnancy; effect of trigonellamide (N1-methylnicotinamide chloride) on pyruvic, lactic, and amino acids in the blood in liver insufficiency in pregnancy].
Topics: Amino Acids; Chlorides; Hepatic Insufficiency; Liver Function Tests; Niacin; Niacinamide; Nicotinic | 1953 |
[Biogenic amines of the placenta. III. Nicotinic acid and nicotinamide content of mature, immature, normal and pathological human placenta].
Topics: Biogenic Amines; Female; Humans; Niacin; Niacinamide; Nicotinic Acids; Placenta; Pregnancy | 1957 |
[Effect of nicotinamide on the pyridine coenzyme content of the rat placenta].
Topics: Animals; Coenzymes; Female; Niacin; Niacinamide; Placenta; Pregnancy; Pyridines; Rats | 1963 |
[DPN-DPNH, TPN-TPNH and pyridine compound content in the liver of the pregnant rat and fetus and in the placenta after large doses of nicotinamide].
Topics: Animals; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; NAD; NADP; Niacin; Niacinamide; Plac | 1963 |
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY INJECTION OF A TERATOGEN IN PREGNANCY.
Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Female; Humans; Injections; Mice; Niac | 1963 |
CONGENITAL ABNORMALITIES IN THE RAT RESULTING FROM SINGLE INJECTIONS OF 6-AMINONICOTINAMIDE DURING PREGNANCY.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Antimetabolites; Brain; Cardiovascular Sy | 1963 |
TERATOGENIC EFFECTS OF HYPOGLYCEMIC TREATMENTS IN INBRED STRAINS OF MICE.
Topics: Abnormalities, Drug-Induced; Animals; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred Strains; Niac | 1963 |
ACQUIRED CHROMOSOMAL ANOMALIES INDUCED IN MICE BY KNOWN TERATOGEN.
Topics: Alloxan; Animals; Chromosome Aberrations; Cleft Palate; Embryo, Mammalian; Embryo, Nonmammalian; Fem | 1964 |
NICOTINAMIDE NUCLEOTIDE COENZYMES AND GLUCOSE METABOLISM IN THE LIVERS OF FOETAL AND NEWBORN LAMBS.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Body Weight; Carbohydrate Metabolism; Coenzymes; | 1963 |
[METABOLISM OF GLUCOSE AND FRUCTOSE IN THE HUMAN PLACENTA].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Carbohydrate Metabolism; Female; Fructose; Glucose; NAD | 1963 |
TERATOGENIC ACTION OF THALIDOMIDE.
Topics: Abnormalities, Drug-Induced; Female; Folic Acid; Glutamine; Niacinamide; Pregnancy; Pregnancy Compli | 1964 |
[INFLUENCE OF VITAMIN PP IN THE PROCESS OF ODONTOGENESIS].
Topics: Animals; Animals, Newborn; Bone and Bones; Calcification, Physiologic; Dental Calculus; Dental Carie | 1963 |
FETAL DEATH FROM NICOTINAMIDE-DEFICIENT DIET AND ITS PREVENTION BY CHLORPROMAZINE AND IMIPRAMINE.
Topics: Animals; Avitaminosis; Chlorpromazine; Diet; Female; Fetal Death; Fetus; Imipramine; Liver; NAD; Nia | 1964 |
THE METABOLISM OF ALPHA-N-MONOMETHYL-L-TRYPTOPHAN (L-ABRIN) IN MAN AND IN NORMAL AND PYRIDOXINE DEFICIENT RATS.
Topics: Abrin; Amino Acids; Body Fluids; Eclampsia; Female; Humans; Kynurenine; Male; Niacin; Niacinamide; P | 1964 |
RESISTANCE OF A-JAX MOUSE EMBRYOS WITH SPONTANEOUS CONGENITAL CLEFT LIP TO THE LETHAL EFFECT OF 6-AMINO-NICOTINAMIDE.
Topics: Animals; Cleft Lip; Female; Genetics; Humans; Mice; Niacinamide; Pregnancy; Research; Toxicology | 1965 |
KINETICS OF NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENATION BY HUMAN PLACENTA.
Topics: Biochemical Phenomena; Biochemistry; Catalysis; Estradiol; Estrone; Female; Humans; Kinetics; NAD; N | 1965 |
CONTENT AND SYNTHESIS OF HEPATIC PYRIDINE NUCLEOTIDES IN FETAL AND NEONATAL RABBITS.
Topics: Aging; Animals; DNA; Female; Fetus; Humans; Liver; Maternal-Fetal Exchange; Metabolism; NAD; NADP; N | 1965 |
Congenital malformations after a two-hour inactivation of nicotinamide in pregnant mice.
Topics: Animals; Congenital Abnormalities; Mice; Niacin; Niacinamide; Nicotinic Acids; Pregnancy | 1960 |
Changes in the urinary excretion of the metabolites of the tryptophan-niacin pathway during pregnancy in Japanese women and rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Female; Gestational Age; Humans; Niacin; Niacin | 2004 |
The effect of a nicorandil congener on isolated human myometrium.
Topics: Adult; Area Under Curve; Dysmenorrhea; Female; Humans; Middle Aged; Myometrium; Niacinamide; Obstetr | 2006 |
Nicotinamide protects against ethanol-induced apoptotic neurodegeneration in the developing mouse brain.
Topics: Animals; Apoptosis; Brain; Central Nervous System Depressants; Ethanol; Female; Fetal Alcohol Spectr | 2006 |
[Bullous pemphigoid: diagnostics and new therapeutic strategies].
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy | 2006 |
Protection against prenatal alcohol-induced damage.
Topics: Adult; Animals; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Female; Fetal A | 2006 |
Fetal alcohol syndrome and essential fatty acids.
Topics: Animals; Central Nervous System Depressants; Ethanol; Fatty Acids, Essential; Female; Fetal Alcohol | 2006 |
Nicotinamide prevents the effect of perinatal asphyxia on dopamine release evaluated with in vivo microdialysis 3 months after birth.
Topics: Amphetamine; Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Central Nervous System Stimu | 2007 |
Plasticity of basal ganglia neurocircuitries following perinatal asphyxia: effect of nicotinamide.
Topics: Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Cell Count; Disease Models | 2007 |
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
Topics: Adult; Child; Drug-Related Side Effects and Adverse Reactions; Epidemiologic Methods; Female; Geneti | 2008 |
In vitro renal transport functions of the progeny of rats with streptozotocin-induced diabetes.
Topics: Aging; Aminoisobutyric Acids; Animals; Biological Transport; Diabetes Mellitus, Experimental; Female | 1982 |
Prevention possibility for brain dysfunction in rat with the fetal alcohol syndrome--low-zinc-status and hypoglycemia.
Topics: Animals; Brain; Carbonic Anhydrases; Central Nervous System Diseases; Ethanol; Female; Fetal Alcohol | 1982 |
[Effect of L-tryptophan, nicotinamide, L-methionine and 1-methylnicotinamide on the embryotoxic effect of various substances].
Topics: 6-Aminonicotinamide; Animals; Cyclophosphamide; Drug Interactions; Embryo, Mammalian; Female; Hydrox | 1983 |
Ultrastructure of initial nasal process cell fusion in spontaneous and 6-aminonicotinamide-induced mouse embryo cleft lip.
Topics: 6-Aminonicotinamide; Animals; Cell Fusion; Cleft Lip; Embryo, Mammalian; Female; Mice; Mice, Inbred | 1983 |
[Efficacy of using coamid to treat viral hepatitis in pregnant women].
Topics: Cobalt; Female; Hepatitis, Viral, Human; Humans; Male; Niacinamide; Organometallic Compounds; Pregna | 1984 |
Modulation of uterine sensitivity to decidual induction in the rat by nicotinamide; challenge and extension of a model of progestational differentiation.
Topics: Animals; Decidua; Embryo Implantation; Female; NAD; NADP; Niacinamide; Pregnancy; Progesterone; Rats | 1984 |
A scanning and transmission electron microscopic study of amoeboid microglial cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Animals; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Microsco | 1984 |
Cerebellar malformation obtained in rats by early postnatal treatment with 6-aminonicotinamide. Role of neuron-glia interactions in cerebellar development.
Topics: 6-Aminonicotinamide; Animals; Cell Movement; Cerebellar Cortex; Cerebellum; Dendrites; Female; Micro | 1980 |
The effect of 6-aminonicotinamide on energy metabolism in rat embryo neural tube.
Topics: 6-Aminonicotinamide; Adenosine Triphosphate; Animals; Brain; Central Nervous System; Embryo, Mammali | 1981 |
No effect of maternal niacin deficiency on niacin metabolism in newborn brain.
Topics: Animals; Animals, Newborn; Brain; Cerebellum; Female; In Vitro Techniques; Kinetics; Maternal-Fetal | 1981 |
Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide.
Topics: Animals; Arginine; Electrophoresis, Gel, Two-Dimensional; Female; Interleukin-1; Islets of Langerhan | 1995 |
Nicotinamide, a component of complex culture media, inhibits mouse embryo development in vitro and reduces subsequent developmental potential after transfer.
Topics: Animals; Blastocyst; Cleavage Stage, Ovum; Culture Media; Culture Techniques; Embryo Transfer; Embry | 1994 |
Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.
Topics: Abortion, Induced; Animals; C-Peptide; Cell Aggregation; Cell Communication; Cell Differentiation; C | 1996 |
In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16.
Topics: Animals; Cells, Cultured; Female; Gestational Age; Glucose; Insulin; Insulin Secretion; Islets of La | 1997 |
Effects of sex hormones on the metabolism of tryptophan to niacin and to serotonin in male rats.
Topics: Animals; Appetite; Body Weight; Brain; Carboxy-Lyases; Eating; Estrone; Female; Gonadal Steroid Horm | 1997 |
Culture of one-cell hamster embryos with water soluble vitamins: pantothenate stimulates blastocyst production.
Topics: Animals; Blastocyst; Choline; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relations | 2000 |
A severe persistent case of recurrent pemphigoid gestationis successfully treated with minocycline and nicotinamide.
Topics: Adult; Anti-Bacterial Agents; Female; Humans; Immunosuppressive Agents; Minocycline; Niacinamide; Pe | 2001 |
Inhibition of DNA synthesis in differentiating cardiac muscle by NAD.
Topics: Animals; Animals, Newborn; Biological Transport, Active; Cell Differentiation; DNA Replication; Fema | 1976 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochro | 1976 |
A fluorimetric method for quantitation in the picomole range of N1-methylnicotinamide and nicotinamide in serum.
Topics: Female; Humans; Hypercholesterolemia; Kinetics; Male; Microchemistry; Niacinamide; Pregnancy; Pregna | 1975 |
Inhibition of ATP synthesis associated with 6-aminonicotinamide (6-AN) teratogenesis in rat embryos.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Dinitrophenols; F | 1975 |
Vitamin supplementation as a possible factor in the incidence of cleft lip/palate deformities in humans.
Topics: Ascorbic Acid; Calcium; Cleft Lip; Cleft Palate; Female; Folic Acid; Humans; Infant, Newborn; Matern | 1976 |
[Embryonic development of hypophysis, adrenal glands and gonads in rat embryos after 6-aminonicotinamide administration].
Topics: 6-Aminonicotinamide; Adrenal Glands; Animals; Endoplasmic Reticulum; Female; Gonads; Maternal-Fetal | 1976 |
Effects of cytosine arabinoside, 6-aminonicotinamide, and 6-mercaptopurine riboside on ectoderm and mesoderm of mouse limb buds.
Topics: 6-Aminonicotinamide; Animals; Cytarabine; DNA; Ectoderm; Embryo, Mammalian; Extremities; Female; Glu | 1977 |
The role of nicotinamide and of certain other modifying factors in diethylnitrosamine carcinogenesis: fusaria mycotoxins and "spontaneous" tumors in animals and man.
Topics: Animals; Diethylnitrosamine; Female; Fusarium; Gastrointestinal Neoplasms; Genital Neoplasms, Female | 1977 |
Effect of 6-aminonicotinamide in teratogenic doses on the DNA- and RNA-concentration in rabbit embryos.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; DNA; Dose-Response Relationship, Drug; Em | 1977 |
6-Aminonicotinamide-induced cleft palate in the mouse: the nature of the difference between the A/J and C57Bl/6J strains in frequency of response and its genetic basis.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship, | 1977 |
A selection experiment for distinct types of 6-aminonicotinamide-induced cleft lip in mice.
Topics: 6-Aminonicotinamide; Animals; Cleft Lip; Crosses, Genetic; Face; Female; Genotype; Male; Mice; Mice, | 1978 |
Correlation between mandibular retrognathia and induction of cleft palate with 6-aminonicotinamide in the rat.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship, | 1979 |
NAD precursors as antiteratogens against aminothiadiazole.
Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Resorption; Gestational Age; Kynurenine; Ma | 1976 |
Control of histone H1 dimer-poly(ADP-ribose) complex formation by poly(ADP-ribose) glycohydrolase.
Topics: Animals; Breast Neoplasms; Cell Line; Cell Nucleus; Female; Glycoside Hydrolases; Histones; Humans; | 1977 |
Congenital hydrocephalus mimicking Dandy-Walker syndrome induced by 6-aminonicotinamide injection in pregnant rat.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Brain; Dandy-Walker Syndrome; Disease Mod | 1991 |
Pyridine nucleotide levels under conditions of 5 alpha-dihydrotestosterone-stimulated 17 beta-estradiol formation from estrone and pathway of nicotinamide adenine dinucleotide biosynthesis in placental villi in vitro.
Topics: Chorionic Villi; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Kinetics; NAD; NADP; Niaci | 1991 |
Supplemental nicotinic acid or nicotinamide for lactating dairy cows.
Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood Glucose; Body Weight; Cattle; Eating; Fatty Acids | 1990 |
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
Topics: Culture Techniques; Female; Glucose; Humans; Insulin; Islets of Langerhans; Niacinamide; Pancreas; P | 1989 |
A comparative study on the NAD glycohydrolase of the maternal and neonatal erythrocytes.
Topics: Enzyme Activation; Erythrocytes; Female; Fetal Blood; Humans; Infant, Newborn; N-Glycosyl Hydrolases | 1985 |
An electron microscopical study of epiplexus and supraependymal cells in the prenatal rat brain following a maternal injection of 6-aminonicotinamide.
Topics: 6-Aminonicotinamide; Animals; Cerebral Ventricles; Choroid Plexus; Ependyma; Female; Hydrocephalus; | 1985 |
Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Fem | 1988 |
Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Male; Mice; Mice, I | 1988 |
Effects of whole cottonseed, niacin, and niacinamide on in vitro rumen fermentation and on lactating Holstein cows.
Topics: Animals; Cattle; Cottonseed Oil; Female; Fermentation; In Vitro Techniques; Lactation; Niacin; Niaci | 1988 |
Biosynthesis of pyridine nucleotides in early embryos of the mouse (Mus musculus).
Topics: Animals; Azaserine; Carbon Isotopes; Chorionic Gonadotropin; Embryo Implantation; Embryo, Mammalian; | 1973 |
Effect of 6-aminonicotinamide and of added vitamin A on fusion of embryonic rat palates in vitro.
Topics: Animals; Autoradiography; Cleft Palate; Culture Media; Female; In Vitro Techniques; Maternal-Fetal E | 1967 |
Stimulating bilirubin conjugation.
Topics: Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Niacinamide; Pregnancy; | 1968 |
Effect of levels of nitrogen intake on tryptophan metabolism and requirement for pregnancy of the rat.
Topics: Animals; Female; Glutamates; Glycine; Male; Niacinamide; Nitrogen; Nucleotides; Pregnancy; Pregnancy | 1967 |
Effects of acute vitamin replacement therapy on 6-aminonicotinamide induced cleft palate late in rat pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy; | 1967 |
Congenital malformations induced by 6-aminonicotinamide in rabbit kits.
Topics: Abnormalities, Drug-Induced; Animals; Eye Abnormalities; Female; Niacinamide; Pregnancy; Pregnancy, | 1967 |
Development of cleft palate induced by 6-aminonicotinamide late in rat gestation.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Female; Niacinamide; Pregnancy; | 1966 |
Failure of steroid hormones to reverse the toxic effects of 6-aminonicotinamide given early in pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Estrone; Female; Fetal Death; Mice; Niacinami | 1967 |
The relation of vitamin-B complex to the effect of thalidomide on the sensitivity of intracellular haemoglobin to oxidation.
Topics: Animals; Erythrocytes; Female; Glutethimide; Hemoglobins; Male; Niacinamide; Oxidation-Reduction; Ph | 1967 |
Effect of transplanted tumor and various agents on liver regeneration during pregnancy.
Topics: Animals; Benzofurans; Carcinoma 256, Walker; Female; Fetal Death; Hepatectomy; Liver Regeneration; N | 1966 |
Pathogenesis of spinal malformations induced in the embryos of mice.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Lumbar Vertebrae; Mice; Niacinamide | 1967 |
A cytoplasmically transmitted, diet-dependent difference in response to the teratogenic effects of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Diet; Extrachromosomal Inheritance; Female; Hybr | 1968 |
6-aminonicotinamide-induced skeletal malformations in mice.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Bone and Bones; Cleft Palate; Female; Fetal D | 1968 |
Nutritional status in Puerto Rican slum area.
Topics: Adolescent; Adult; Aged; Anthropometry; Child; Child, Preschool; Deficiency Diseases; Diet; Erythroc | 1968 |
Direct effects of 6-aminonicotinamide on the developing rat embryo in vitro and in vivo.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Antimetabolites; Cleft Palate; Culture Media; Culture | 1968 |
[Experimental studies on the development of malformations of the extremities. 2. On the process of the development of tibia defects].
Topics: Abnormalities, Drug-Induced; Animals; Female; Maternal-Fetal Exchange; Mice; Niacinamide; Pregnancy; | 1968 |
[Metoclopramide does not influence urinary elimination of N-methylnicotinamide and 5-OH-indoleacetic acid].
Topics: Adult; Amides; Benzoates; Female; Humans; Indoleacetic Acids; Injections, Intramuscular; Nausea; Nia | 1968 |
The effects of starvation or of treatment with cytotoxic agents on pregnancy in mice.
Topics: Aminopterin; Animals; Antineoplastic Agents; Body Weight; Dactinomycin; Embryo, Mammalian; Embryonic | 1969 |
[Use of hemotransfusion in the complex therapy of anemias during hypotonic hemorrhages in labor].
Topics: Anemia, Hypochromic; Ascorbic Acid; Blood Transfusion; Female; Hematopoiesis; Humans; Iron; Niacinam | 1969 |
Is there an optimal stage for the induction of cleft palate in the mouse?
Topics: Animals; Cleft Palate; Cyclophosphamide; Dexamethasone; Female; Mice; Niacinamide; Pregnancy; Pregna | 1969 |
Tryptophan metabolism as affected by anovulatory agents.
Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kyn | 1969 |
[Clinical and experimental studies of delta phalanx of the hallux].
Topics: Abnormalities, Drug-Induced; Animals; Child; Child, Preschool; Female; Hallux; Humans; Infant, Newbo | 1969 |
Stimulation of renal organic acid transport and protein synthesis by penicillin.
Topics: Aminohippuric Acids; Ammonium Chloride; Animals; Biological Transport, Active; Body Fluids; Body Wei | 1970 |
Variations in drug metabolism during mammalian development genetic aspects.
Topics: Animals; Biotransformation; Embryo, Mammalian; Enzyme Induction; Female; Fetus; Genetic Variation; M | 1970 |
Effects of deficiencies in labile methyl groups on the growth and development of fetal rats.
Topics: Animals; Choline; Congenital Abnormalities; Deficiency Diseases; Diet; Embryonic and Fetal Developme | 1970 |
[Disturbances of tooth development in rat embryos following administration of 6-aminonicotinamide].
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Incisor; Microscopy, Electron; Niac | 1970 |
Further studies on a cytoplasmically transmitted difference in response to the teratogen 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Diet; Extrachromosomal Inheritance; F | 1968 |
Biochemical studies of the embryotoxic action of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Acetates; Aspartic Acid; Carbon Isotopes; DNA; Embryo, Mammalian; Embry | 1970 |
Electron microscope studies on the effect of 6-aminonicotinamide on mammalian embryos.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Culture Techniques; Ectoderm; Embryo, Mammalian; Female | 1970 |
Embryonic abnormalities in hamsters following intrauterine injection of 6-aminonicotinamide.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Anophthalmos; Brain; Cleft Palate; Cricetinae; | 1971 |
The effects of intraamniotic injection of dexamethasone in rats.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Cleft Palate; Dexamethasone; Drug Synergism; Ext | 1971 |
Influence of maternal age and parity on fetal mortality and congenital abnormalities induced in rats.
Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Cleft Palate; Eye Abnormalities; Female; Feta | 1971 |
[Ambulatory therapy of pregnancy toxicoses].
Topics: Ambulatory Care; Ascorbic Acid; Female; Fetus; Folic Acid; Humans; Niacinamide; Pre-Eclampsia; Pregn | 1970 |
[Disturbed embryonic mitosis in rabbits after administration of 6-aminonicotinic acid amide].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Embryo, Mammalian; Female; Fibroblasts; Liver; Mitosis | 1972 |
[Experiments on the induction and prevention of malformations in rabbits].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Animals, Newborn; Antimetabolites; Cell Division; Cong | 1972 |
Nicotinic acid loading of normal cows: effects on blood metabolites and excretory forms.
Topics: Administration, Oral; Animals; Blood Glucose; Cattle; Diuresis; Fatty Acids, Nonesterified; Female; | 1972 |
[Vitamins. 9. Niacin].
Topics: Adult; Ascorbic Acid Deficiency; Developing Countries; Diet; Female; Food; Humans; Infant; Infant Nu | 1972 |
6-Aminonicotinamide (6-AN)-induced abnormalities of the developing ependyma and choroid plexus as seen with the scanning electron microscope.
Topics: Abnormalities, Drug-Induced; Animals; Cell Membrane; Choroid Plexus; Cilia; Ependyma; Female; Fetus; | 1972 |
[Vitamins C, PP and B-6 in the blood and placenta in the developmental dynamics of pregnancy and labor normally and in obstetrical pathology].
Topics: Ascorbic Acid; Blood Chemical Analysis; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Lab | 1973 |
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; F | 1973 |
Cell proliferation in the cranial base of A-J mice with 6-AN-induced cleft palate.
Topics: Animals; Autoradiography; Cartilage; Cell Division; Cleft Lip; Cleft Palate; Female; Fetus; Gestatio | 1973 |
A survey of the embryotoxic effects of TCDD in mammalian species.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Amines; Animals; Cleft Palate; Cyclo | 1973 |
[Preliminary teratological experiments with mini-pigs ("Göttinger miniaturschwein") (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Disease Models, Animal; Female; Gestational Age; Niacinamide; | 1973 |
[Experimental studies on the boundary sensitive phase of embryonal development of "Göttingen miniature pigs"].
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Embryonic and Fetal Developm | 1973 |
Relation of mandible growth to palate closure in mice.
Topics: Amines; Animals; Body Weight; Cleft Palate; Cortisone; Female; Gestational Age; Mandible; Maxillofac | 1974 |
[Tryptophan metabolism in screening metabolic diseases of the newborn].
Topics: Amino Acid Metabolism, Inborn Errors; Evaluation Studies as Topic; Female; Humans; Infant, Newborn; | 1973 |
[Phase-specific pattern of malformation in the Goettinger miniature pig following administration of 6-amino-nicotinamide].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Laboratory; Female; Fetus; Injections, Intraperitonea | 1974 |
[Vitamins C, PP and B6 in the blood and placenta in the dynamics of the development of pregnancy and labor normally and in obstetrical pathology].
Topics: Ascorbic Acid; Female; Humans; Labor, Obstetric; Niacinamide; Obstetric Labor Complications; Placent | 1973 |
The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway.
Topics: Adolescent; Adult; Aged; Androgens; Animals; Estrogens; Female; Humans; Hydrocortisone; Hydrolases; | 1974 |
[Effect of 6-aminonicotinic acid amide in teratogenic dosis on the ATP-concentration in rabbit embryos].
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Amines; Animals; Embryo, Mammalian; Female; Nia | 1974 |
Effect of streptozotocin-diabetes on in vivo protein synthesis by placenta and liver of mice.
Topics: Animals; Blood Glucose; Body Weight; Carbon Radioisotopes; Diabetes Mellitus; Female; Insulin; Leuci | 1974 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; | 1974 |
The effects of intravenously administered water-soluble vitamins during labor in normovitaminemic and hypovitaminemic gravidas on maternal and neonatal blood vitamin levels at delivery.
Topics: Adolescent; Adult; Ascorbic Acid; Avitaminosis; Biotin; Female; Folic Acid; Humans; Infant, Newborn; | 1974 |
Reduction of 6-aminonicotinamide teratogenicity in mice by etherization.
Topics: Abnormalities, Drug-Induced; Anesthesia, Inhalation; Animals; Cleft Lip; Ether; Ethyl Ethers; Female | 1970 |
Induction of a cytoplasmic factor increasing resistance to the teratogenic effect of 6-aminonicotinamide in mice.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytoplasm; Enzyme Induction | 1973 |
Prevention and remission by adrenocortical steroids of nicotinamide deficiency disorders and of 6-aminonicotinamide toxicity in rats and dogs.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Deficiency Diseases; Desoxycorticosterone; Dex | 1966 |
The pathway of synthesis of mammary-gland nicotinamide-adenine dinucleotide.
Topics: Animals; Female; Lactation; Liver; Mammary Glands, Animal; NAD; Niacinamide; Pregnancy; Rats | 1967 |
The pathway of biosynthesis of nicotinamide-adenine dinucleotide in rat mammary gland.
Topics: Animals; Female; Glucosyltransferases; Kinetics; Lactation; Mammary Glands, Animal; Models, Biologic | 1968 |
Tryptophan and nitrogen metabolism and pregnancy of the rat as affected by dietary supplementations with leucine and with amino acid mixtures.
Topics: Amino Acids; Animals; Deficiency Diseases; Diet; Dietary Proteins; Feces; Female; Fetal Death; Fetus | 1970 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
Teratology in the Macaca mulatta.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Clomiphene; Encephalocele; Female; Fetal Death; Haplo | 1968 |
[Induction and prevention of developmental abnormalities in rabbits by administration of 6-aminonicotinic acid and nicotinic acid amide].
Topics: Abnormalities, Drug-Induced; Amines; Animals; Female; Fetus; Gestational Age; Microphthalmos; Mouth | 1971 |
Studies on reduction of azo-linkages in human placental homogenates.
Topics: Azo Compounds; Carbon Monoxide; Edetic Acid; Female; Flavins; Glucosephosphate Dehydrogenase; Glutat | 1968 |
Effect of some beta-pyridyl derivatives and of histamine on the rat uterus under different functional states.
Topics: Animals; Estrus; Ethanolamines; Female; Histamine; Histamine H1 Antagonists; Kymography; Methanol; N | 1969 |
[The stabilization of glucose-6-phosphate dehydrogenase in the rat mammary gland].
Topics: Animals; Female; Glucosephosphate Dehydrogenase; Glutathione; Hexosephosphates; In Vitro Techniques; | 1969 |
Factors influencing placental steroidogenesis.
Topics: 17-Ketosteroids; Adenosine Triphosphate; Androstenes; Animals; Carbon Isotopes; Cholesterol; Chorion | 1972 |
The morphology of various types of cell death in prenatal tissues.
Topics: Abnormalities, Drug-Induced; Animals; Cell Survival; Cyclophosphamide; Dactinomycin; Embryo, Mammali | 1973 |