niacinamide has been researched along with Pemphigus in 18 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Pemphigus: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Minocycline/tetracycline is clinically used for the treatment of bullous pemphigoid (BP), and its clinical benefits are superior to those of prednisolone when considering adverse events." | 7.88 | Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs. ( Aiba, S; Fujimura, T; Lyu, C; Sato, Y; Tanita, K, 2018) |
| "To highlight the exceptional but successful use of minocycline/nicotinamide monotherapy in pemphigus vegetans." | 7.85 | Successful monotherapy of pemphigus vegetans with minocycline and nicotinamide. ( Bonsmann, G; Luger, T; Metze, D; Ständer, S; von Köckritz, A; Zeidler, C, 2017) |
| "We review the response of pemphigus patients to tetracycline, doxycycline, or minocycline plus niacinamide (TCN/NAM) as steroid-sparing therapy and to determine the effects of TCN/NAM on autoantibody levels during the long-term treatment of pemphigus." | 7.80 | Two decades of using the combination of tetracycline derivatives and niacinamide as steroid-sparing agents in the management of pemphigus: defining a niche for these low toxicity agents. ( Fivenson, D; McCarty, M, 2014) |
| "Minocycline is another possible alternative therapy for pemphigus vulgaris." | 7.71 | [Oral pemphigus vulgaris. Successful treatment with minocycline and nicotinamide]. ( Beltraminelli, H; Büchner, SA; Gutersohn, T; Häusermann, P; Rufli, T; Schiller, P, 2002) |
| "Pemphigus and pemphigoid are different types of autoimmune bullous disease and can occur in the same patient." | 5.36 | Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist. ( Hasegawa, J; Hashimoto, T; Ohyama, B; Oyama, B; Saida, T; Shiohara, J; Takata, M; Uhara, H; Yoshida, K, 2010) |
| "Minocycline/tetracycline is clinically used for the treatment of bullous pemphigoid (BP), and its clinical benefits are superior to those of prednisolone when considering adverse events." | 3.88 | Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs. ( Aiba, S; Fujimura, T; Lyu, C; Sato, Y; Tanita, K, 2018) |
| "To highlight the exceptional but successful use of minocycline/nicotinamide monotherapy in pemphigus vegetans." | 3.85 | Successful monotherapy of pemphigus vegetans with minocycline and nicotinamide. ( Bonsmann, G; Luger, T; Metze, D; Ständer, S; von Köckritz, A; Zeidler, C, 2017) |
| "We review the response of pemphigus patients to tetracycline, doxycycline, or minocycline plus niacinamide (TCN/NAM) as steroid-sparing therapy and to determine the effects of TCN/NAM on autoantibody levels during the long-term treatment of pemphigus." | 3.80 | Two decades of using the combination of tetracycline derivatives and niacinamide as steroid-sparing agents in the management of pemphigus: defining a niche for these low toxicity agents. ( Fivenson, D; McCarty, M, 2014) |
| "Minocycline is another possible alternative therapy for pemphigus vulgaris." | 3.71 | [Oral pemphigus vulgaris. Successful treatment with minocycline and nicotinamide]. ( Beltraminelli, H; Büchner, SA; Gutersohn, T; Häusermann, P; Rufli, T; Schiller, P, 2002) |
| "A combination of niacinamide and tetracycline was used to treat 31 dogs with various autoimmune skin diseases (discoid lupus erythematosus, pemphigus foliaceus, pemphigus erythematosus, and bullous pemphigoid)." | 3.68 | Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs. ( Paradis, M; Reinke, SI; Rosychuk, RA; White, SD, 1992) |
| "The development of nonhormonal treatment of pemphigus vulgaris (PV) has been hampered by a lack of clear understanding of the mechanisms leading to keratinocyte (KC) detachment and death in pemphigus." | 2.78 | Mechanisms of mitochondrial damage in keratinocytes by pemphigus vulgaris antibodies. ( Chen, Y; Chernyavsky, A; Deng, W; Grando, SA; Kalantari-Dehaghi, M; Marchenko, S; Wang, PH, 2013) |
| "Pemphigus is a rare autoimmune bullous disorder." | 2.47 | [Pemphigus: a review]. ( Joly, P; Sin, C, 2011) |
| "Pemphigus is an autoimmune skin disease that can present in a variety of forms and can be a challenging disease to manage and treat." | 2.42 | Pemphigus: current therapy. ( Rosenkrantz, WS, 2004) |
| "Pemphigus and pemphigoid are different types of autoimmune bullous disease and can occur in the same patient." | 1.36 | Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist. ( Hasegawa, J; Hashimoto, T; Ohyama, B; Oyama, B; Saida, T; Shiohara, J; Takata, M; Uhara, H; Yoshida, K, 2010) |
| "I report a patient with phenylketonuria who presented with pemphigus foliaceus or tinea amiantacea." | 1.32 | A case of co-incident phenylketonuria, pemphigus foliaceus, and tinea amiantacea treated with tetracycline and nicotinamide. ( Scheinfeld, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanita, K | 1 |
| Fujimura, T | 1 |
| Sato, Y | 1 |
| Lyu, C | 1 |
| Aiba, S | 1 |
| Kalantari-Dehaghi, M | 1 |
| Chen, Y | 1 |
| Deng, W | 1 |
| Chernyavsky, A | 1 |
| Marchenko, S | 1 |
| Wang, PH | 1 |
| Grando, SA | 1 |
| McCarty, M | 1 |
| Fivenson, D | 1 |
| Wu, C | 1 |
| Zuo, Y | 1 |
| Jin, H | 1 |
| Chen, J | 1 |
| Li, L | 1 |
| von Köckritz, A | 1 |
| Ständer, S | 1 |
| Zeidler, C | 1 |
| Metze, D | 1 |
| Luger, T | 1 |
| Bonsmann, G | 1 |
| Shiohara, J | 1 |
| Yoshida, K | 1 |
| Hasegawa, J | 1 |
| Uhara, H | 1 |
| Takata, M | 1 |
| Saida, T | 1 |
| Ohyama, B | 1 |
| Oyama, B | 1 |
| Hashimoto, T | 2 |
| Joly, P | 1 |
| Sin, C | 1 |
| Häusermann, P | 1 |
| Gutersohn, T | 1 |
| Beltraminelli, H | 1 |
| Schiller, P | 1 |
| Büchner, SA | 1 |
| Rufli, T | 1 |
| Scheinfeld, N | 1 |
| Chen, S | 1 |
| Lu, X | 1 |
| Zhou, G | 1 |
| Rosenkrantz, WS | 1 |
| Bolling, MC | 1 |
| Mekkes, JR | 1 |
| Goldschmidt, WF | 1 |
| van Noesel, CJ | 1 |
| Jonkman, MF | 1 |
| Pas, HH | 1 |
| Alpsoy, E | 1 |
| Yilmaz, E | 1 |
| Basaran, E | 1 |
| Yazar, S | 1 |
| Cetin, L | 1 |
| Sawai, T | 1 |
| Kitazawa, K | 1 |
| Danno, K | 1 |
| Sugie, N | 1 |
| Machizuki, T | 1 |
| Sugiura, H | 1 |
| Uehara, M | 1 |
| Chaffins, ML | 1 |
| Collison, D | 1 |
| Fivenson, DP | 1 |
| Fimiani, M | 1 |
| Rubegni, P | 1 |
| Flori, ML | 1 |
| De Aloe, G | 1 |
| Andreassi, L | 1 |
| Izu, K | 1 |
| Yamamoto, O | 1 |
| Masuyuki, K | 1 |
| Asahi, M | 1 |
| Komai, R | 1 |
| Yasumoto, S | 1 |
| White, SD | 1 |
| Rosychuk, RA | 1 |
| Reinke, SI | 1 |
| Paradis, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blinded, Placebo-Controlled Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaris[NCT00135720] | Phase 2 | 12 participants (Anticipated) | Interventional | 2004-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for niacinamide and Pemphigus
| Article | Year |
|---|---|
[Pemphigus: a review].
Topics: Adrenal Cortex Hormones; Combined Modality Therapy; Drug Therapy, Combination; Epidermal Growth Fact | 2011 |
Pemphigus: current therapy.
Topics: Animals; Antirheumatic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Dapsone; | 2004 |
2 trials available for niacinamide and Pemphigus
| Article | Year |
|---|---|
Mechanisms of mitochondrial damage in keratinocytes by pemphigus vulgaris antibodies.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Autoantibodies; Cell Line, Transformed; Cyclosporine; Enz | 2013 |
Is the combination of tetracycline and nicotinamide therapy alone effective in pemphigus?
Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Niacinamide; Pemphigus; T | 1995 |
14 other studies available for niacinamide and Pemphigus
| Article | Year |
|---|---|
Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antigens, CD; Antig | 2018 |
Two decades of using the combination of tetracycline derivatives and niacinamide as steroid-sparing agents in the management of pemphigus: defining a niche for these low toxicity agents.
Topics: Anti-Inflammatory Agents; Clobetasol; Doxycycline; Drug Therapy, Combination; Humans; Minocycline; N | 2014 |
Treatment of pemphigus herpetiformis with minocycline and nicotinamide.
Topics: Aged; Anti-Bacterial Agents; Dermatitis Herpetiformis; Female; Humans; Minocycline; Niacinamide; Pem | 2014 |
Successful monotherapy of pemphigus vegetans with minocycline and nicotinamide.
Topics: Aged; Female; Humans; Minocycline; Niacinamide; Pemphigus | 2017 |
Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist.
Topics: Autoantigens; Collagen Type XVII; Desmoglein 1; Drug Therapy, Combination; Female; Humans; Middle Ag | 2010 |
[Oral pemphigus vulgaris. Successful treatment with minocycline and nicotinamide].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Minocycline; Mouth Mucosa; Niacinamide; Pemphigus; | 2002 |
A case of co-incident phenylketonuria, pemphigus foliaceus, and tinea amiantacea treated with tetracycline and nicotinamide.
Topics: Adult; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Niacinamide; Pemphigus; Phe | 2003 |
Mild pemphigus foliaceus responding to combination therapy with niacinamide and tetracycline.
Topics: Anti-Bacterial Agents; Diagnosis, Differential; Drug Therapy, Combination; Facial Dermatoses; Humans | 2003 |
Acquired palmoplantar keratoderma and immunobullous disease associated with antibodies to desmocollin 3.
Topics: Antibodies; Desmocollins; Humans; Keratoderma, Palmoplantar; Male; Middle Aged; Niacinamide; Pemphig | 2007 |
Pemphigus vegetans with oesophageal involvement: successful treatment with minocycline and nicotinamide.
Topics: Drug Therapy, Combination; Esophageal Diseases; Female; Humans; Middle Aged; Minocycline; Niacinamid | 1995 |
Treatment of pemphigus and linear IgA dermatosis with nicotinamide and tetracycline: a review of 13 cases.
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Humans; Immunoglobulin A; Male; M | 1993 |
Treatment of Pemphigus senilis with tetracycline plus nicotinamide: long term follow-up.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Contraindications; Drug Combinations; Female; Follow | 1997 |
[A case of pemphigus foliaceus associated with bullous impetigo successfully treated with tetracycline and nicotinamide].
Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Impetigo; Middle Aged; Niacinamide | 2001 |
Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs.
Topics: Animals; Autoimmune Diseases; Dog Diseases; Dogs; Drug Combinations; Female; Lupus Erythematosus, Di | 1992 |