Page last updated: 2024-10-19

niacinamide and Pemphigoid

niacinamide has been researched along with Pemphigoid in 38 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"The combination of nicotinamide and tetracycline has been anecdotally reported to be effective in the treatment of bullous pemphigoid."9.07Nicotinamide and tetracycline therapy of bullous pemphigoid. ( Breneman, DL; Cardone, S; Fivenson, DP; Hersh, CS; Mutasim, D; Rosen, GB, 1994)
"Minocycline/tetracycline is clinically used for the treatment of bullous pemphigoid (BP), and its clinical benefits are superior to those of prednisolone when considering adverse events."7.88Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs. ( Aiba, S; Fujimura, T; Lyu, C; Sato, Y; Tanita, K, 2018)
"To study the efficacy of tetracycline (or doxycycline) and nicotinamide in the treatment of less extensive bullous pemphigoid."7.70Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore. ( Goon, AT; Khoo, LS; Tan, SH; Tan, T, 2000)
"In 1986, Berk and Lorincz reported the efficacy of tetracycline and nicotinamide in the treatment of bullous pemphigoid (BP)."7.69Bullous pemphigoid successfully controlled by tetracycline and nicotinamide. ( Bos, WH; De Jong, MC; Jonkman, MF; Kolbach, DN; Pas, HH; Remme, JJ; van der Meer, JB, 1995)
"Clobetasol propionate cream applied over the whole body is probably similarly effective as, and may cause less mortality than, oral prednisone for treating bullous pemphigoid."5.41Interventions for bullous pemphigoid. ( Anchan, VN; Boyle, RJ; Chi, CC; Kirtschig, G; Murrell, DF; Singh, S; Taghipour, K, 2023)
"Pemphigus and pemphigoid are different types of autoimmune bullous disease and can occur in the same patient."5.36Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist. ( Hasegawa, J; Hashimoto, T; Ohyama, B; Oyama, B; Saida, T; Shiohara, J; Takata, M; Uhara, H; Yoshida, K, 2010)
"The combination of nicotinamide and tetracycline has been anecdotally reported to be effective in the treatment of bullous pemphigoid."5.07Nicotinamide and tetracycline therapy of bullous pemphigoid. ( Breneman, DL; Cardone, S; Fivenson, DP; Hersh, CS; Mutasim, D; Rosen, GB, 1994)
"Minocycline/tetracycline is clinically used for the treatment of bullous pemphigoid (BP), and its clinical benefits are superior to those of prednisolone when considering adverse events."3.88Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs. ( Aiba, S; Fujimura, T; Lyu, C; Sato, Y; Tanita, K, 2018)
"A case of bullous pemphigoid responding to niacinamide as monotherapy is reported."3.70Autoimmune bullous eruption localized to a breast reconstruction site: response to niacinamide. ( Elston, DM; Honl, BA, 1998)
"To study the efficacy of tetracycline (or doxycycline) and nicotinamide in the treatment of less extensive bullous pemphigoid."3.70Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore. ( Goon, AT; Khoo, LS; Tan, SH; Tan, T, 2000)
"In 1986, Berk and Lorincz reported the efficacy of tetracycline and nicotinamide in the treatment of bullous pemphigoid (BP)."3.69Bullous pemphigoid successfully controlled by tetracycline and nicotinamide. ( Bos, WH; De Jong, MC; Jonkman, MF; Kolbach, DN; Pas, HH; Remme, JJ; van der Meer, JB, 1995)
"A combination of niacinamide and tetracycline was used to treat 31 dogs with various autoimmune skin diseases (discoid lupus erythematosus, pemphigus foliaceus, pemphigus erythematosus, and bullous pemphigoid)."3.68Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs. ( Paradis, M; Reinke, SI; Rosychuk, RA; White, SD, 1992)
"Bullous pemphigoid is the most common autoimmune bullous disease in the West."2.43Interventions for bullous pemphigoid. ( Hollis, S; Khumalo, N; Kirtschig, G; Middleton, P; Murrell, D; Wojnarowska, F, 2005)
"Bullous pemphigoid is the most common autoimmune bullous disease in the West."2.42Interventions for bullous pemphigoid. ( Hollis, S; Khumalo, N; Kirtschig, G; Middleton, P; Murrell, D; Wojnarowska, F, 2003)
"Bronchiolitis obliterans is a small-airway obstructive lung disease for which immunologically mediated pathogenesis is supposed."1.46Non-paraneoplastic autoimmune subepidermal bullous disease associated with fatal bronchiolitis obliterans. ( Abe, R; Hashidate, H; Hashimoto, T; Hokari, S; Ishii, N; Kanekura, T; Kawai, K; Narita, JI; Orime, M; Tomiyama, K; Tsuda, A; Uchida, Y; Yokoyama, H; Yoshida, S, 2017)
"Pemphigus and pemphigoid are different types of autoimmune bullous disease and can occur in the same patient."1.36Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist. ( Hasegawa, J; Hashimoto, T; Ohyama, B; Oyama, B; Saida, T; Shiohara, J; Takata, M; Uhara, H; Yoshida, K, 2010)
"Stump pemphigoid is a localized variant of bullous pemphigoid characterized by specific clinical, pathological, and immunofluorescent characteristics."1.29Stump pemphigoid. ( Brodell, RT; Korman, NJ, 1996)
"As the conservative management of breast cancer is now widely adopted, oncologists and physicians should be aware of such rare side effects due to radiation therapy."1.29Bullous pemphigoid induced by radiation therapy. ( Amanti, C; Di Paola, M; Folliero, G; Tombolini, V; Zurlo, A, 1995)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.26)18.7374
1990's11 (28.95)18.2507
2000's11 (28.95)29.6817
2010's12 (31.58)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Hsieh, CY1
Tsai, TF1
Singh, S1
Kirtschig, G5
Anchan, VN1
Chi, CC1
Taghipour, K1
Boyle, RJ1
Murrell, DF3
Tanita, K1
Fujimura, T1
Sato, Y1
Lyu, C1
Aiba, S1
Kalinska-Bienias, A1
Kowalczyk, E1
Jagielski, P1
Kowalewski, C1
Wozniak, K1
Huang, MX1
Li, ZS1
Luo, DQ1
Lin, Q1
Zhiliang, L1
Peiying, J1
Suying, F1
Orime, M1
Tomiyama, K1
Hashidate, H1
Yoshida, S1
Hokari, S1
Tsuda, A1
Yokoyama, H1
Narita, JI1
Uchida, Y1
Kanekura, T1
Abe, R1
Ishii, N1
Hashimoto, T5
Kawai, K1
Chen, TJ1
Lai, PC1
Yang, LC1
Kuo, TT1
Hong, HS1
Koga, H1
Hamada, T1
Ohyama, B2
Nakama, T1
Yasumoto, S1
Shiohara, J1
Yoshida, K1
Hasegawa, J1
Uhara, H1
Takata, M1
Saida, T1
Oyama, B1
Geiss Steiner, J1
Trüeb, RM1
Kerl, K1
Mühleisen, B1
French, LE1
Hofbauer, GF1
Middleton, P3
Bennett, C1
Wojnarowska, F4
Khumalo, NP2
Kusajima, E1
Akiyama, M1
Sato, M1
Natsuga, K1
Shimizu, H1
Bernard, P1
Charneux, J1
Daniel, BS1
Borradori, L1
Hall, RP1
Tsuruta, D1
Nishikawa, T1
Yamagami, J1
Amato, L1
Coronella, G1
Berti, S1
Gallerani, I1
Moretti, S1
Fabbri, P1
Khumalo, N2
Hollis, S2
Murrell, D2
Hofmann, SC1
Bruckner-Tuderman, L1
Kolbach, DN1
Remme, JJ1
Bos, WH1
Jonkman, MF1
De Jong, MC1
Pas, HH1
van der Meer, JB1
Fivenson, DP2
Breneman, DL1
Rosen, GB1
Hersh, CS1
Cardone, S1
Mutasim, D1
Brodell, RT1
Korman, NJ1
Folliero, G1
Zurlo, A1
Amanti, C1
Tombolini, V1
Di Paola, M1
Hornschuh, B1
Hamm, H1
Wever, S1
Schröder, U1
Bröcker, EB3
Zillikens, D3
Kimbrough, TL1
Honl, BA1
Elston, DM1
Hara, H1
Fujitsuka, A1
Morishima, C1
Kurihara, N1
Yamaguchi, Z1
Morishima, T1
Schmidt, E2
Obe, K1
Goon, AT1
Tan, SH1
Khoo, LS1
Tan, T1
Reimer, S1
Kruse, N1
Loo, WJ1
Dean, D1
White, SD1
Rosychuk, RA1
Reinke, SI1
Paradis, M1
Oranje, AP1
Vuzevski, VD1
van Joost, T1
ten Kate, F1
Naafs, B1
Yao, LJ1
Middleton, RK1
Berk, MA1
Lorincz, AL1
Duschet, P1
Schwarz, T1
Gschnait, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open Randomized Comparative Trial of Four Different Dressings for Cutaneous Coverage in Pemphigus and Pemphigoid[NCT02365675]12 participants (Anticipated)Interventional2015-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for niacinamide and Pemphigoid

ArticleYear
Management of Coexisting Bullous Pemphigoid and Psoriasis: A Review.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:6

    Topics: Acitretin; Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Biological Factors; Biologi

2022
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2023, 08-11, Volume: 8

    Topics: Azathioprine; Clobetasol; Dapsone; Doxycycline; Humans; Methylprednisolone; Niacinamide; Pemphigoid,

2023
Bullous pemphigoid in a renal transplant recipient: a case report and review of the literature.
    American journal of clinical dermatology, 2009, Volume: 10, Issue:3

    Topics: Administration, Cutaneous; Anti-Infective Agents; Clobetasol; Dapsone; Doxycycline; Fatal Outcome; G

2009
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: Azathioprine; Clobetasol; Combined Modality Therapy; Drug Therapy, Combination; Drugs, Chinese Herba

2010
[Bullous pemphigoid: a review].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:3

    Topics: Aged; Azathioprine; Clobetasol; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug

2011
Evidence-based management of bullous pemphigoid.
    Dermatologic clinics, 2011, Volume: 29, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Autoantibodies; Azathioprine; Clinical Trials as Top

2011
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2003, Issue:3

    Topics: Azathioprine; Glucocorticoids; Humans; Immunosuppressive Agents; Niacinamide; Pemphigoid, Bullous; P

2003
Management of bullous pemphigoid: recommendations for immunomodulatory treatments.
    American journal of clinical dermatology, 2004, Volume: 5, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Child; Glucocorticoids; Humans; Immunoglobul

2004
Interventions for bullous pemphigoid.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Azathioprine; Glucocorticoids; Humans; Immunosuppressive Agents; Niacinamide; Pemphigoid, Bullous; P

2005

Trials

2 trials available for niacinamide and Pemphigoid

ArticleYear
Nicotinamide and tetracycline therapy of bullous pemphigoid.
    Archives of dermatology, 1994, Volume: 130, Issue:6

    Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle

1994
Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid.
    Archives of dermatology, 2000, Volume: 136, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Aut

2000

Other Studies

27 other studies available for niacinamide and Pemphigoid

ArticleYear
Minocycline decreases Th2 chemokines from M2 macrophages: Possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs.
    Experimental dermatology, 2018, Volume: 27, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antigens, CD; Antig

2018
Tetracycline, nicotinamide, and lesionally administered clobetasol as a therapeutic option to prednisone in patients with bullous pemphigoid: a comparative, retrospective analysis of 106 patients with long-term follow-up.
    International journal of dermatology, 2019, Volume: 58, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Clobetasol; Drug Therapy,

2019
Bullous pemphigoid-like eruption subsequent to scabies: bullous scabies or bullous pemphigoid?
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015, Volume: 150, Issue:3

    Topics: Aged; Autoantibodies; Autoantigens; Carrier Proteins; Causality; Collagen Type XVII; Cytoskeletal Pr

2015
Diagnosis of pemphigoid nodularis with serological assay.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2016, Volume: 151, Issue:1

    Topics: Administration, Cutaneous; Anti-Bacterial Agents; Biopsy; Drug Therapy, Combination; Enzyme-Linked I

2016
Non-paraneoplastic autoimmune subepidermal bullous disease associated with fatal bronchiolitis obliterans.
    The Journal of dermatology, 2017, Volume: 44, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Autoantibodies; Autoantigens; Basement Membrane; Biopsy; Bronchiolitis

2017
An association of idiopathic chronic eosinophilic pneumonia with pemphigoid nodularis: a rare variant of bullous pemphigoid.
    Archives of dermatology, 2009, Volume: 145, Issue:11

    Topics: Aged; Biopsy, Needle; Chronic Disease; Diagnosis, Differential; Enzyme-Linked Immunosorbent Assay; F

2009
Tetracycline and niacinamide control bullous pemphigoid but not pemphigus foliaceus when these conditions coexist.
    The Journal of dermatology, 2010, Volume: 37, Issue:7

    Topics: Autoantigens; Collagen Type XVII; Desmoglein 1; Drug Therapy, Combination; Female; Humans; Middle Ag

2010
Ecthyma-gangrenosum-like bullous pemphigoid.
    Dermatology (Basel, Switzerland), 2010, Volume: 221, Issue:2

    Topics: Adrenal Cortex Hormones; Aged, 80 and over; Anti-Bacterial Agents; Autoantibodies; Autoantigens; Chr

2010
Type XVII collagen ELISA indices significantly decreased after bullous pemphigoid remission.
    International journal of dermatology, 2011, Volume: 50, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Azathioprine; Cohort Studies; Collagen

2011
Unilateral bullous pemphigoid without erythema and eosinophil infiltration in a hemiplegic patient.
    The Journal of dermatology, 2012, Volume: 39, Issue:9

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Autoantigens; Collagen Type XVII; Eosinophils; Hem

2012
Successful treatment with doxycycline and nicotinamide of two cases of persistent pemphigoid gestationis.
    The Journal of dermatological treatment, 2002, Volume: 13, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Doxycycline; Female; Humans; Niacinamide; Pemphigoid, Bullous; Pregnan

2002
[Bullous pemphigoid: diagnostics and new therapeutic strategies].
    Deutsche medizinische Wochenschrift (1946), 2006, Feb-24, Volume: 131, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Biopsy

2006
Bullous pemphigoid successfully controlled by tetracycline and nicotinamide.
    The British journal of dermatology, 1995, Volume: 133, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Combinations; Female; Follow-Up Studies;

1995
Stump pemphigoid.
    Cutis, 1996, Volume: 57, Issue:4

    Topics: Amputation Stumps; Anti-Bacterial Agents; Biopsy; Fluorescent Antibody Technique; Humans; Male; Midd

1996
Bullous pemphigoid induced by radiation therapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1995, Volume: 7, Issue:4

    Topics: Anti-Bacterial Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Dermatologic Agents; Female; Hum

1995
Treatment of 16 patients with bullous pemphigoid with oral tetracycline and niacinamide and topical clobetasol.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:1

    Topics: Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cl

1997
Lichen planus pemphigoides: combination therapy with tetracycline and nicotinamide.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:4

    Topics: Drug Therapy, Combination; Female; Humans; Lichen Planus; Middle Aged; Niacinamide; Pemphigoid, Bull

1997
Autoimmune bullous eruption localized to a breast reconstruction site: response to niacinamide.
    Cutis, 1998, Volume: 62, Issue:2

    Topics: Autoimmune Diseases; Breast Diseases; Dermatologic Agents; Diagnosis, Differential; Female; Humans;

1998
Severe drug-induced pneumonitis associated with minocycline and nicotinamide therapy of a bullous pemphigoid.
    Acta dermato-venereologica, 1998, Volume: 78, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Fatal Outcome; Humans; Male; Minocycline; Niacinamid

1998
Tetracycline and nicotinamide for the treatment of bullous pemphigoid: our experience in Singapore.
    Singapore medical journal, 2000, Volume: 41, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Complement C3; Diarrhea; Doxycycline; Drug Combinations; Female; Fluore

2000
The IL-8 release from cultured human keratinocytes, mediated by antibodies to bullous pemphigoid autoantigen 180, is inhibited by dapsone.
    Clinical and experimental immunology, 2001, Volume: 124, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Autoantigens; Cells, Cultured; Che

2001
A severe persistent case of recurrent pemphigoid gestationis successfully treated with minocycline and nicotinamide.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Immunosuppressive Agents; Minocycline; Niacinamide; Pe

2001
Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs.
    Journal of the American Veterinary Medical Association, 1992, May-15, Volume: 200, Issue:10

    Topics: Animals; Autoimmune Diseases; Dog Diseases; Dogs; Drug Combinations; Female; Lupus Erythematosus, Di

1992
Bullous pemphigoid in children. Report of three cases with special emphasis on therapy.
    International journal of dermatology, 1991, Volume: 30, Issue:5

    Topics: Adolescent; Autoimmune Diseases; Child; Drug Therapy, Combination; Erythromycin; Humans; Male; Niaci

1991
Niacinamide for bullous pemphigoid.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:11

    Topics: Aged; Female; Humans; Male; Niacinamide; Pemphigoid, Bullous; Treatment Outcome

1991
The treatment of bullous pemphigoid with tetracycline and niacinamide. A preliminary report.
    Archives of dermatology, 1986, Volume: 122, Issue:6

    Topics: Administration, Oral; Aged; Drug Therapy, Combination; Erythromycin; Female; Humans; Male; Niacinami

1986
Bullous pemphigoid after radiation therapy.
    Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:2 Pt 2

    Topics: Aged; Diagnosis, Differential; Humans; Lymecycline; Lymphatic Metastasis; Male; Niacinamide; Pemphig

1988