Page last updated: 2024-10-19

niacinamide and Nerve Pain

niacinamide has been researched along with Nerve Pain in 16 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia."8.02Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021)
"Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia."4.02Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021)
" In addition, the effect of intrathecal injection of NAD or resveratrol on thermal hyperalgesia and mechanical allodynia was evaluated in CCI mice."3.80Spinal SIRT1 activation attenuates neuropathic pain in mice. ( Ding, W; Luo, Y; Shao, H; Xue, Q; Yu, B; Zhang, F; Zhang, H; Zhang, X; Zhu, H, 2014)
"Peripheral neuropathic pain induced by the chemotherapeutic cisplatin can persist for months to years after treatment."1.72HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling. ( Grace, PM; Heijnen, CJ; Junigan, JM; Kavelaars, A; Trinh, R; Zhang, J, 2022)
"Sorafenib treatments did not affect paw-withdrawal responses to non-noxious or to noxious mechanical stimuli."1.42A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. ( Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Maresca, M; Scherz, MW, 2015)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's6 (37.50)24.3611
2020's6 (37.50)2.80

Authors

AuthorsStudies
Cheng, YC1
Chiu, YM1
Dai, ZK1
Wu, BN1
Zhang, J1
Junigan, JM1
Trinh, R1
Kavelaars, A1
Heijnen, CJ1
Grace, PM1
Tian, S1
Wu, L1
Zheng, H1
Zhong, X1
Yu, X1
Wu, W1
Tanei, T2
Maesawa, S2
Nishimura, Y2
Nagashima, Y2
Ishizaki, T2
Ando, M2
Kuwatsuka, Y2
Hashizume, A2
Kurasawa, S2
Saito, R2
Braga, AV1
Costa, SOAM1
Rodrigues, FF1
Melo, ISF1
Morais, MI1
Coelho, MM1
Machado, RR1
Bhattacharya, A1
Wang, Q1
Ao, H1
Shoblock, JR1
Lord, B1
Aluisio, L1
Fraser, I1
Nepomuceno, D1
Neff, RA1
Welty, N1
Lovenberg, TW1
Bonaventure, P1
Wickenden, AD1
Letavic, MA1
Shao, H1
Xue, Q1
Zhang, F1
Luo, Y1
Zhu, H1
Zhang, X1
Zhang, H1
Ding, W1
Yu, B1
Di Cesare Mannelli, L1
Maresca, M1
Farina, C1
Scherz, MW1
Ghelardini, C1
Zhang, XF1
Shieh, CC1
Chapman, ML1
Matulenko, MA1
Hakeem, AH1
Atkinson, RN1
Kort, ME1
Marron, BE1
Joshi, S1
Honore, P1
Faltynek, CR1
Krafte, DS1
Jarvis, MF1
McGaraughty, S1
Chu, KL1
Cowart, MD1
Brioni, JD1
Sharma, M1
Dash, SS1
Matharasala, G1
Deekshith, V1
Sriram, D1
Yogeeswari, P1
PIVA, S2
Medhurst, SJ1
Collins, SD1
Billinton, A1
Bingham, S1
Dalziel, RG1
Brass, A1
Roberts, JC1
Medhurst, AD1
Chessell, IP1
Buzzelli, G1

Trials

2 trials available for niacinamide and Nerve Pain

ArticleYear
Differential target multiplexed spinal cord stimulation using a paddle-type lead placed at the appropriate site for neuropathic pain after spinal cord injury in patients with past spinal surgical histories: study protocol for an exploratory clinical trial
    Trials, 2023, Jun-13, Volume: 24, Issue:1

    Topics: Embryo Implantation; Humans; Neuralgia; Niacinamide; Patients; Randomized Controlled Trials as Topic

2023
Efficacy of the latest new stimulation patterns of spinal cord stimulation for intractable neuropathic pain compared to conventional stimulation: study protocol for a clinical trial.
    Trials, 2023, Sep-23, Volume: 24, Issue:1

    Topics: Embryo Implantation; Humans; Japan; Neuralgia; Niacinamide; Randomized Controlled Trials as Topic; S

2023

Other Studies

14 other studies available for niacinamide and Nerve Pain

ArticleYear
Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats.
    Cells, 2021, 10-08, Volume: 10, Issue:10

    Topics: Animals; Antioxidants; Behavior, Animal; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide

2021
HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022, 10-19, Volume: 42, Issue:42

    Topics: Analgesics, Opioid; Animals; Antibodies, Neutralizing; Antineoplastic Agents; Cisplatin; Enkephalin,

2022
Identification of autophagy-related genes in neuropathic pain through bioinformatic analysis.
    Hereditas, 2023, Mar-01, Volume: 160, Issue:1

    Topics: Autophagy; Computational Biology; Humans; MicroRNAs; Neuralgia; Niacinamide; Nucleotides; Quality of

2023
Thiamine, riboflavin, and nicotinamide inhibit paclitaxel-induced allodynia by reducing TNF-α and CXCL-1 in dorsal root ganglia and thalamus and activating ATP-sensitive potassium channels.
    Inflammopharmacology, 2020, Volume: 28, Issue:1

    Topics: Animals; Chemokine CXCL1; Ganglia, Spinal; Hyperalgesia; KATP Channels; Male; Mice; Neuralgia; Niaci

2020
Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.
    British journal of pharmacology, 2013, Volume: 170, Issue:3

    Topics: Adenosine Triphosphate; Analgesics; Animals; Antidepressive Agents; Antimanic Agents; Behavior, Anim

2013
Spinal SIRT1 activation attenuates neuropathic pain in mice.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Down-Regulation; Hyperalgesia; Male; Mice; Mice, Inbred Strains; NAD; Neuralgia; Niacinamid

2014
A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam.
    Neurotoxicology, 2015, Volume: 50

    Topics: Analgesics; Analysis of Variance; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Respo

2015
A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.
    Neuropharmacology, 2010, Volume: 59, Issue:3

    Topics: Animals; Biophysics; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Elec

2010
Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 343, Issue:1

    Topics: Animals; Benzazepines; Histamine H3 Antagonists; Locus Coeruleus; Male; Neuralgia; Neurons; Niacinam

2012
Novel piperazinyl derivatives with anti-hyperalgesic, anti-allodynic and anti-inflammatory activities useful for the treatment of Neuropathic Pain.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2012, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Female; Hyperalgesia; Male; Mice; Neuralgia; Niacinamide; Piperaz

2012
[Clinical use of a combination of adenosine triphosphoric acid (ATP), cocarboxylase, vitamin B12 and nicotinamide (PP) in the therapy of neuralgia and neuritis].
    Le Scalpel, 1960, May-28, Volume: 113

    Topics: Adenine Nucleotides; Adenosine; Humans; Neuralgia; Neuritis; Niacin; Niacinamide; Nicotinic Acids; P

1960
[On the clinical use of a combination of adenosine-triphosphoric acid, (A.T.P.), cocarboxylase, vitamin B12 and nicotinamide (vitamin PP) in the therapy of neuralgia and neuritis].
    Gazzetta medica italiana, 1959, Volume: 118

    Topics: Adenine Nucleotides; Adenosine; Neuralgia; Neuritis; Niacin; Niacinamide; Nicotinic Acids; Polyphosp

1959
Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic pain.
    Pain, 2008, Aug-15, Volume: 138, Issue:1

    Topics: Animals; Azepines; Benzazepines; Disease Models, Animal; Herpes Zoster; Histamine H3 Antagonists; Hu

2008
[Therapeutic action of a new pyrazole-vitamin association compared with that of the vitamin complex alone. Comparative clinico-experimental study].
    Minerva medica, 1971, Dec-26, Volume: 62, Issue:98

    Topics: Adult; Aged; Aminopyrine; Antipyrine; Drug Combinations; Female; Humans; Male; Middle Aged; Neuralgi

1971