Page last updated: 2024-10-19

niacinamide and Neoplasms, Pleural

niacinamide has been researched along with Neoplasms, Pleural in 10 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Sorafenib is well tolerated in patients with mesothelioma after completion of platinum-containing chemotherapy."9.17Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy. ( Barrington, S; Cane, P; Dunn, JT; Lal, R; Landau, D; Lang-Lazdunski, L; McLennan, B; Papa, S; Popat, S; Prevost, AT; Shah, R; Spicer, J; Viney, Z, 2013)
"We analyzed the molecular mechanisms of the antiproliferative effects of sorafenib in mesothelioma TIC cultures."7.85The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells. ( Barbieri, F; Carra, E; Daga, A; Favoni, RE; Filiberti, RA; Florio, T; Marubbi, D; Mutti, L; Pattarozzi, A; Würth, R, 2017)
"Sorafenib is a potent inhibitor of the ras/raf/MEK pathway and also targets VEGFR and cKIT."6.75A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307. ( Crawford, J; Dubey, S; Heinze, R; Jänne, PA; Kindler, HL; Kratzke, R; Krug, L; Pang, H; Vokes, E; Wang, X; Watt, C, 2010)
"Sorafenib is well tolerated in patients with mesothelioma after completion of platinum-containing chemotherapy."5.17Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy. ( Barrington, S; Cane, P; Dunn, JT; Lal, R; Landau, D; Lang-Lazdunski, L; McLennan, B; Papa, S; Popat, S; Prevost, AT; Shah, R; Spicer, J; Viney, Z, 2013)
"We analyzed the molecular mechanisms of the antiproliferative effects of sorafenib in mesothelioma TIC cultures."3.85The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells. ( Barbieri, F; Carra, E; Daga, A; Favoni, RE; Filiberti, RA; Florio, T; Marubbi, D; Mutti, L; Pattarozzi, A; Würth, R, 2017)
"THERE WERE 62 PATIENTS (37 MEN, MEAN AGE: 61 years) treated with sorafenib (62%), sunitinib (22%), and vandetanib (16%) outside of clinical trials; 22 had papillary, five had follicular, five had Hürthle cell, 13 had poorly differentiated, and 17 had medullary thyroid carcinoma (MTC)."3.80Tyrosine kinase inhibitor treatments in patients with metastatic thyroid carcinomas: a retrospective study of the TUTHYREF network. ( Baudin, E; Bonichon, F; Borget, I; Brassard, M; Chougnet, CN; Claude-Desroches, M; de la Fouchardière, C; Do Cao, C; Giraudet, AL; Leboulleux, S; Massicotte, MH; Schlumberger, M, 2014)
"Sorafenib is a potent inhibitor of the ras/raf/MEK pathway and also targets VEGFR and cKIT."2.75A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307. ( Crawford, J; Dubey, S; Heinze, R; Jänne, PA; Kindler, HL; Kratzke, R; Krug, L; Pang, H; Vokes, E; Wang, X; Watt, C, 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's7 (70.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pattarozzi, A1
Carra, E1
Favoni, RE1
Würth, R1
Marubbi, D1
Filiberti, RA1
Mutti, L1
Florio, T1
Barbieri, F1
Daga, A1
Papa, S1
Popat, S1
Shah, R1
Prevost, AT1
Lal, R1
McLennan, B1
Cane, P1
Lang-Lazdunski, L1
Viney, Z1
Dunn, JT1
Barrington, S1
Landau, D1
Spicer, J1
Massicotte, MH1
Brassard, M1
Claude-Desroches, M1
Borget, I1
Bonichon, F1
Giraudet, AL1
Do Cao, C1
Chougnet, CN1
Leboulleux, S1
Baudin, E1
Schlumberger, M1
de la Fouchardière, C1
Simonelli, M1
Zucali, PA1
Suter, MB1
Lorenzi, E1
Rubino, L1
Fatuzzo, G1
Alloisio, M1
Santoro, A1
Pignochino, Y1
Dell'Aglio, C1
Inghilleri, S1
Zorzetto, M1
Basiricò, M1
Capozzi, F1
Canta, M1
Piloni, D1
Cemmi, F1
Sangiolo, D1
Gammaitoni, L1
Soster, M1
Marchiò, S1
Pozzi, E1
Morbini, P1
Luisetti, M1
Aglietta, M1
Grignani, G1
Stella, GM1
Azad, A1
Herbertson, RA1
Pook, D1
White, S1
Mitchell, PL1
Tebbutt, NC1
Desar, IM1
Mulder, SF1
Stillebroer, AB1
van Spronsen, DJ1
van der Graaf, WT1
Mulders, PF1
van Herpen, CM1
Katz, SI1
Zhou, L1
Chao, G1
Smith, CD1
Ferrara, T1
Wang, W1
Dicker, DT1
El-Deiry, WS1
Hou, MM1
Hsieh, JJ1
Chang, NJ1
Huang, HY1
Wang, HM1
Chuang, CK1
Hsu, T1
Chang, JW1
Dubey, S1
Jänne, PA1
Krug, L1
Pang, H1
Wang, X1
Heinze, R1
Watt, C1
Crawford, J1
Kratzke, R1
Vokes, E1
Kindler, HL1

Reviews

1 review available for niacinamide and Neoplasms, Pleural

ArticleYear
Targeted therapy for thymic epithelial tumors: a new horizon? Review of the literature and two cases reports.
    Future oncology (London, England), 2015, Volume: 11, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ErbB Receptors; Female; Histone Deacetylase In

2015

Trials

2 trials available for niacinamide and Neoplasms, Pleural

ArticleYear
Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013, Volume: 8, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm;

2013
A phase II study of sorafenib in malignant mesothelioma: results of Cancer and Leukemia Group B 30307.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2010, Volume: 5, Issue:10

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Extracellular Signal-Regulated MAP Kinases; Female;

2010

Other Studies

7 other studies available for niacinamide and Neoplasms, Pleural

ArticleYear
The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells.
    Stem cell research & therapy, 2017, 05-25, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Separation; C

2017
Tyrosine kinase inhibitor treatments in patients with metastatic thyroid carcinomas: a retrospective study of the TUTHYREF network.
    European journal of endocrinology, 2014, Volume: 170, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Oxyphilic; Adult; Aged; Antineoplastic Agents;

2014
The combination of sorafenib and everolimus shows antitumor activity in preclinical models of malignant pleural mesothelioma.
    BMC cancer, 2015, May-08, Volume: 15

    Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cyt

2015
Motesanib diphosphate (AMG 706), an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:4

    Topics: Administration, Oral; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols

2009
The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases.
    Acta oncologica (Stockholm, Sweden), 2009, Volume: 48, Issue:6

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidn

2009
Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.
    Cancer biology & therapy, 2009, Volume: 8, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Caspase 3; Cell Line, Tumor; Extracell

2009
Response to sorafenib in a patient with metastatic xp11 translocation renal cell carcinoma.
    Clinical drug investigation, 2010, Volume: 30, Issue:11

    Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Chromosomes, Human, X; Disease-Free

2010