niacinamide has been researched along with Myocardial Ischemia in 53 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "These experiments were designed to explore the possibility that a K+ channel opener which also donates nitric oxide to the myocardium (nicorandil) may modify ischaemia-induced ventricular arrhythmias in a large animal model." | 7.69 | Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia. ( Györgyi, K; Papp, JG; Parratt, JR; Sakai, K; Vegh, A, 1996) |
| "Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem." | 7.69 | Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996) |
| "We report five patients who developed intraoperative myocardial ischemia but were treated successfully with nicorandil." | 7.69 | [Successful treatment of intraoperative myocardial ischemia with nicorandil]. ( Hanaoka, K; Hayashida, M; Ito, N; Kawamura, S; Komatsu, K; Kuzumi, E; Orii, R; Sawamura, S, 1997) |
| "Nicorandil treatment did not change the altered heart rate variability in either time domain or spectral analysis." | 6.68 | Effects of short-term treatment of nicorandil on exercise-induced myocardial ischemia and abnormal cardiac autonomic activity in microvascular angina. ( Chang, MS; Chen, JW; Hsu, NW; Lee, WL; Lin, SJ; Ting, CT; Wang, SP, 1997) |
| " The aim of the studies was to establish the effects of sublingually or orally applied nicorandil (N) on pacing-induced myocardial ischemia (MIS)." | 4.79 | Effects of nicorandil on regional perfusion and left ventricular function. ( Berwing, K; Mitrovic, V; Schlepper, M; Strasser, R; Thormann, J, 1995) |
| "These experiments were designed to explore the possibility that a K+ channel opener which also donates nitric oxide to the myocardium (nicorandil) may modify ischaemia-induced ventricular arrhythmias in a large animal model." | 3.69 | Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia. ( Györgyi, K; Papp, JG; Parratt, JR; Sakai, K; Vegh, A, 1996) |
| "Effects of CD-832 on isoproterenol (ISO)-induced myocardial ischemia were studied in dogs with partial coronary stenosis of the left circumflex coronary artery and findings were compared with those for nifedipine or diltiazem." | 3.69 | Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis. ( Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K, 1996) |
| "We report five patients who developed intraoperative myocardial ischemia but were treated successfully with nicorandil." | 3.69 | [Successful treatment of intraoperative myocardial ischemia with nicorandil]. ( Hanaoka, K; Hayashida, M; Ito, N; Kawamura, S; Komatsu, K; Kuzumi, E; Orii, R; Sawamura, S, 1997) |
| "Myocardial ischemia was measured as the magnitude of ST-segment elevation on the intracoronary electrocardiogram (intracoronary ECG) recorded from the guidewire." | 2.68 | Antiischemic effects of nicorandil during coronary angioplasty in humans. ( Fukui, T; Hibiya, K; Honye, J; Kamata, T; Mizumura, T; Moriuchi, M; Ozawa, Y; Saito, S; Takayama, T; Tamura, Y, 1995) |
| "Nicorandil treatment did not change the altered heart rate variability in either time domain or spectral analysis." | 2.68 | Effects of short-term treatment of nicorandil on exercise-induced myocardial ischemia and abnormal cardiac autonomic activity in microvascular angina. ( Chang, MS; Chen, JW; Hsu, NW; Lee, WL; Lin, SJ; Ting, CT; Wang, SP, 1997) |
| "Nicorandil is a balanced arterial and venodilator that may also possess cardioprotective properties via its activation of ATP-sensitive potassium channels." | 2.39 | Potassium channel openers: clinical applications in ischemic heart disease--overview of clinical efficacy of nicorandil. ( Fox, K; Knight, C; Purcell, H, 1995) |
| "Nicorandil is a new vasodilator agent." | 2.38 | Clinical profile of nicorandil: an overview of its hemodynamic properties and therapeutic efficacy. ( Krumenacker, M; Roland, E, 1992) |
| "Type 2 diabetes was induced by injection of streptozotocin and nicotinamide." | 1.43 | Effects of Nitrate Intake on Myocardial Ischemia-Reperfusion Injury in Diabetic Rats. ( Bageripour, F; Ghanbari, M; Ghasemi, A; Jeddi, S; Khalifi, S, 2016) |
| "Treatment with small molecule tyrosine kinase inhibitors (TKIs) has improved survival in many cancers, yet has been associated with an increased risk of adverse events." | 1.42 | Cardiovascular toxicity of multi-tyrosine kinase inhibitors in advanced solid tumors: a population-based observational study. ( Amir, E; Ethier, JL; Krzyzanowska, MK; Ocana, A; Seruga, B; Srikanthan, A, 2015) |
| "Nicorandil is a compound with hybrid properties of nitrates and adenosine triphosphate (ATP)-sensitive potassium channel (KATP) opening." | 1.29 | Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs. ( Branzi, A; Galiè, N; Guarnieri, C; Magnani, B; Parlangeli, R; Traini, AM; Ussia, GP; Vaona, I; Zimarino, M, 1995) |
| "Nicorandil is a clinically used nitrovasodilator that has a property as an opener of ATP-sensitive potassium (KATP) channels in vitro." | 1.29 | Nicorandil augments regional ischemia-induced monophasic action potential shortening and potassium accumulation without serious proarrhythmia. ( Asanagi, M; Mitamura, H; Miyazaki, T; Miyoshi, S; Moritani, K; Ogawa, S; Zhao, LS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.89) | 18.7374 |
| 1990's | 44 (83.02) | 18.2507 |
| 2000's | 3 (5.66) | 29.6817 |
| 2010's | 5 (9.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraris, D | 1 |
| Ko, YS | 1 |
| Pahutski, T | 1 |
| Ficco, RP | 1 |
| Serdyuk, L | 1 |
| Alemu, C | 1 |
| Bradford, C | 1 |
| Chiou, T | 1 |
| Hoover, R | 1 |
| Huang, S | 1 |
| Lautar, S | 1 |
| Liang, S | 1 |
| Lin, Q | 1 |
| Lu, MX | 1 |
| Mooney, M | 1 |
| Morgan, L | 1 |
| Qian, Y | 1 |
| Tran, S | 1 |
| Williams, LR | 1 |
| Wu, QY | 1 |
| Zhang, J | 1 |
| Zou, Y | 1 |
| Kalish, V | 1 |
| Li, W | 1 |
| Zhu, L | 1 |
| Ruan, ZB | 1 |
| Wang, MX | 1 |
| Ren, Y | 1 |
| Lu, W | 1 |
| Srikanthan, A | 1 |
| Ethier, JL | 1 |
| Ocana, A | 1 |
| Seruga, B | 1 |
| Krzyzanowska, MK | 1 |
| Amir, E | 1 |
| Jeddi, S | 1 |
| Khalifi, S | 1 |
| Ghanbari, M | 1 |
| Bageripour, F | 1 |
| Ghasemi, A | 1 |
| Kang, SM | 1 |
| Park, JC | 1 |
| Shin, MJ | 1 |
| Lee, H | 1 |
| Oh, J | 1 |
| Ryu, DH | 1 |
| Hwang, GS | 1 |
| Chung, JH | 1 |
| Kardash, OF | 1 |
| Shestakova, LG | 1 |
| Krachak, DI | 1 |
| Chernookiĭ, OG | 1 |
| Zasetskiĭ, AE | 1 |
| Ostrovskiĭ, IuP | 1 |
| GHIA, G | 1 |
| MEREU, D | 1 |
| Szabó, G | 1 |
| Liaudet, L | 1 |
| Hagl, S | 1 |
| Szabó, C | 1 |
| Mego, M | 1 |
| Reckova, M | 1 |
| Obertova, J | 1 |
| Sycova-Mila, Z | 1 |
| Brozmanova, K | 1 |
| Mardiak, J | 1 |
| Qiu, Y | 1 |
| Galiñanes, M | 1 |
| Hearse, DJ | 1 |
| Nakae, I | 1 |
| Quan, L | 1 |
| Sugimoto, Y | 1 |
| Tsutamoto, T | 1 |
| Kinoshita, M | 1 |
| Schlepper, M | 1 |
| Thormann, J | 1 |
| Berwing, K | 1 |
| Strasser, R | 1 |
| Mitrovic, V | 1 |
| Knight, C | 1 |
| Purcell, H | 1 |
| Fox, K | 1 |
| Saito, S | 1 |
| Mizumura, T | 1 |
| Takayama, T | 1 |
| Honye, J | 1 |
| Fukui, T | 1 |
| Kamata, T | 1 |
| Moriuchi, M | 1 |
| Hibiya, K | 1 |
| Tamura, Y | 1 |
| Ozawa, Y | 1 |
| Ribeiro, C | 1 |
| Kodama, K | 1 |
| Adachi, H | 1 |
| Mori, N | 1 |
| Saito, I | 1 |
| Shetty, K | 1 |
| Specchia, G | 2 |
| Marsico, F | 2 |
| Laudisa, ML | 1 |
| Popescu, LM | 1 |
| Musat, S | 1 |
| Trifan, OC | 1 |
| Leabu, M | 1 |
| Tigaret, CM | 1 |
| Popescu, M | 1 |
| Popescu, A | 1 |
| Hinescu, ME | 1 |
| Moraru, II | 1 |
| Das, DK | 1 |
| Yamazaki, J | 2 |
| Iida, M | 2 |
| Igarashi, M | 1 |
| Hosoi, H | 2 |
| Ishiguro, S | 1 |
| Hou, M | 1 |
| Morishita, T | 2 |
| Nakano, H | 2 |
| Yabe, Y | 2 |
| Koyama, N | 2 |
| Hellwig, B | 1 |
| Cavero, I | 2 |
| Premmereur, J | 1 |
| Iwamoto, T | 1 |
| Miura, T | 1 |
| Urabe, K | 1 |
| Itoya, M | 1 |
| Shimamoto, K | 1 |
| Iimura, O | 1 |
| Orita, H | 1 |
| Fukasawa, M | 1 |
| Hirooka, S | 1 |
| Minowa, T | 1 |
| Uchino, H | 1 |
| Washio, M | 1 |
| Nakaya, H | 1 |
| Auchampach, JA | 3 |
| Gross, GJ | 3 |
| Suryapranata, H | 1 |
| Warltier, DC | 1 |
| Ohsawa, H | 1 |
| Uchi, T | 1 |
| Komatsu, H | 1 |
| Menasché, P | 2 |
| Kevelaitis, E | 1 |
| Mouas, C | 2 |
| Grousset, C | 2 |
| Piwnica, A | 1 |
| Bloch, G | 1 |
| Galiè, N | 1 |
| Guarnieri, C | 1 |
| Ussia, GP | 1 |
| Zimarino, M | 1 |
| Traini, AM | 1 |
| Parlangeli, R | 1 |
| Vaona, I | 1 |
| Branzi, A | 1 |
| Magnani, B | 1 |
| Miyazaki, T | 3 |
| Moritani, K | 3 |
| Miyoshi, S | 3 |
| Asanagi, M | 2 |
| Zhao, LS | 1 |
| Mitamura, H | 1 |
| Ogawa, S | 3 |
| Vegh, A | 1 |
| Györgyi, K | 1 |
| Papp, JG | 1 |
| Sakai, K | 1 |
| Parratt, JR | 1 |
| Takahashi, T | 1 |
| Takahashi, K | 1 |
| Kishi-Tanikawa, S | 1 |
| Tsuchida, K | 1 |
| Araki, H | 1 |
| Higuchi, S | 1 |
| Grover, GJ | 2 |
| Kitakaze, M | 1 |
| Minamino, T | 1 |
| Node, K | 1 |
| Komamura, K | 1 |
| Shinozaki, Y | 1 |
| Chujo, M | 2 |
| Mori, H | 1 |
| Inoue, M | 1 |
| Hori, M | 1 |
| Kamada, T | 1 |
| Perrone Filardi, P | 1 |
| Chiariello, M | 1 |
| Micheletti, T | 1 |
| Bona, M | 1 |
| Kawamura, S | 1 |
| Hayashida, M | 1 |
| Orii, R | 1 |
| Sawamura, S | 1 |
| Komatsu, K | 1 |
| Ito, N | 1 |
| Kuzumi, E | 1 |
| Hanaoka, K | 1 |
| Critz, SD | 1 |
| Liu, GS | 1 |
| Downey, JM | 1 |
| Chen, JW | 1 |
| Lee, WL | 1 |
| Hsu, NW | 1 |
| Lin, SJ | 1 |
| Ting, CT | 1 |
| Wang, SP | 1 |
| Chang, MS | 1 |
| Piriou, V | 1 |
| Ross, S | 1 |
| Pigott, D | 1 |
| Evans, R | 1 |
| Foex, P | 1 |
| Rioufol, G | 1 |
| Ovize, M | 1 |
| Loufoua, J | 1 |
| Pop, C | 1 |
| André-Fouät, X | 1 |
| Minaire, Y | 1 |
| Shinohara, H | 1 |
| Nishikado, A | 1 |
| Wakatsuki, T | 1 |
| Sakabe, K | 1 |
| Ito, S | 1 |
| Krumenacker, M | 1 |
| Roland, E | 1 |
| Sasaki, J | 1 |
| Saeki, Y | 1 |
| Kawasaki, K | 1 |
| Umeno, M | 1 |
| Ikeda, K | 1 |
| Handa, K | 1 |
| Arakawa, K | 1 |
9 reviews available for niacinamide and Myocardial Ischemia
| Article | Year |
|---|---|
Poly(ADP-ribose) polymerase activation in the reperfused myocardium.
Topics: Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Models, Animal; Myocardial I | 2004 |
Effects of nicorandil on regional perfusion and left ventricular function.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Echocardiography; Humans; Myocardial Ischemia | 1995 |
Potassium channel openers: clinical applications in ischemic heart disease--overview of clinical efficacy of nicorandil.
Topics: Angina Pectoris; Animals; Anti-Arrhythmia Agents; Hemodynamics; Humans; Myocardial Ischemia; Niacina | 1995 |
Prescribing for angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Humans; Myocardial | 1994 |
[Potassium agonists].
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Humans; Membrane Potentials; Muscle, Smooth, Vascular; My | 1994 |
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; G | 1993 |
Coronary haemodynamics and vasodilatory profile of a potassium channel opener in patients with coronary artery disease.
Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug | 1993 |
Pharmacology of ATP-sensitive potassium channel (KATP) openers in models of myocardial ischemia and reperfusion.
Topics: Animals; ATP-Binding Cassette Transporters; Benzopyrans; Cromakalim; Guanidines; Humans; Ischemic Pr | 1997 |
Clinical profile of nicorandil: an overview of its hemodynamic properties and therapeutic efficacy.
Topics: Diltiazem; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; V | 1992 |
5 trials available for niacinamide and Myocardial Ischemia
| Article | Year |
|---|---|
[Effect of cytoflavin on the recovery of cognitive function after the cardiaс surgery with artificial blood circulation].
Topics: Assisted Circulation; Cognition; Cognition Disorders; Drug Combinations; Female; Flavin Mononucleoti | 2011 |
Antiischemic effects of nicorandil during coronary angioplasty in humans.
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Blood Pressure; Coronary Angiography; | 1995 |
[Clinical use of potassium channel activators in angina pectoris: efficacy and tolerance].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cross-Over Studies; Dose-Response Relationship, Drug; | 1995 |
Effects of short-term treatment of nicorandil on exercise-induced myocardial ischemia and abnormal cardiac autonomic activity in microvascular angina.
Topics: Administration, Oral; Aged; Angina Pectoris; Coronary Angiography; Cross-Over Studies; Double-Blind | 1997 |
A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease.
Topics: Aged; Apolipoproteins; Diltiazem; Female; Humans; Lipids; Lipoproteins; Male; Middle Aged; Myocardia | 1992 |
39 other studies available for niacinamide and Myocardial Ischemia
| Article | Year |
|---|---|
Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries.
Topics: Animals; Aza Compounds; Brain Ischemia; Dogs; Enzyme Inhibitors; Haplorhini; Humans; In Vitro Techni | 2003 |
Nicotinamide protects chronic hypoxic myocardial cells through regulating mTOR pathway and inducing autophagy.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cardiotonic Agents; Caspase 3; Cell Hypo | 2019 |
Cardiovascular toxicity of multi-tyrosine kinase inhibitors in advanced solid tumors: a population-based observational study.
Topics: Adult; Aged, 80 and over; Canada; Cardiovascular Diseases; Female; Humans; Indoles; Male; Middle Age | 2015 |
Effects of Nitrate Intake on Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2016 |
¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure.
Topics: Acetic Acid; Acetone; Aged; Case-Control Studies; Cytosine; Energy Metabolism; Female; Glycine; Hear | 2011 |
[CLINICAL OBSERVATIONS AND THERAPEUTIC RESULTS IN SUBJECTS WITH ISCHEMIC CARDIOPATHY TREATED WITH AN ENZYME COMPLEX ASSOCIATED WITH A VASODILATOR DRUG].
Topics: Adenosine Triphosphate; Coronary Disease; Drug Therapy; Electrocardiography; Flavin Mononucleotide; | 1964 |
Increased cardiotoxicity of sorafenib in sunitinib-pretreated patients with metastatic renal cell carcinoma.
Topics: Aged; Atrial Fibrillation; Benzenesulfonates; Carcinoma, Renal Cell; Cardiovascular Diseases; Chest | 2007 |
Protective effect of nicorandil as an additive to the solution for continuous warm cardioplegia.
Topics: Animals; Cardioplegic Solutions; Coronary Circulation; Dose-Response Relationship, Drug; Heart; Hear | 1995 |
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia.
Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Crom | 1994 |
[Therapeutic application of myocardial cytoprotection].
Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Carnitine; Hum | 1994 |
Effects of a novel, selective and potent phosphodiesterase type V inhibitor, E4021, on myocardial ischemia in guinea pigs.
Topics: Animals; Drug Interactions; Electrocardiography; Guinea Pigs; Injections, Intravenous; Isosorbide Di | 1994 |
[K-channel activators and cardioprotection].
Topics: Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels | 1993 |
K(+)-channel openers protect the myocardium against ischemia-reperfusion injury.
Topics: Animals; In Vitro Techniques; Lipid Metabolism; Myocardial Ischemia; Myocardial Reperfusion Injury; | 1994 |
Evaluation of the efficacy of nicorandil in patients with ischemic heart disease by exercise Tl-201 myocardial SPECT.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Antihypertensive Ag | 1994 |
Evolving Issues in the Treatment of Ischaemic Heart Disease: The Potassium Channel Openers. Symposium proceedings. Barcelona, Spain, 2 September 1992.
Topics: Animals; Anti-Arrhythmia Agents; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Cha | 1993 |
ATP sensitive potassium channel openers are of potential benefit in ischaemic heart disease.
Topics: Benzopyrans; Cromakalim; Dihydropyridines; Guanidines; Humans; Myocardial Ischemia; Myocardium; Niac | 1994 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating | 1993 |
Prevention of postischemic reperfusion injury: the improvement of myocardial tissue blood flow after ischemia by terminal nicorandil-Mg cardioplegia.
Topics: Animals; Blood Flow Velocity; Carbon Dioxide; Cardioplegic Solutions; Coronary Vessels; Dogs; Glucos | 1993 |
Anti-ischaemic actions of potassium channel openers in experimental myocardial ischaemia/reperfusion injury in dogs.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; | 1993 |
Relationship of severity of myocardial stunning to ATP dependent potassium channel modulation.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Glyburide; Myocardial Contraction; Myoc | 1993 |
Study of the efficacy of nicorandil in patients with ischaemic heart disease using Exercise-T1-201 myocardial tomography.
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Circu | 1993 |
Preconditioning with potassium channel openers. A new concept for enhancing cardioplegic protection?
Topics: Animals; Coronary Circulation; Glyburide; Heart Arrest, Induced; Male; Myocardial Ischemia; Myocardi | 1995 |
Limitation of myocardial infarct size by nicorandil after sustained ischemia in pigs.
Topics: Animals; Blood Pressure; Cardiac Output; Female; Glutathione; Heart Rate; Isosorbide Dinitrate; Male | 1995 |
Nicorandil augments regional ischemia-induced monophasic action potential shortening and potassium accumulation without serious proarrhythmia.
Topics: Action Potentials; Animals; Coronary Circulation; Dogs; Myocardial Ischemia; Niacinamide; Nicorandil | 1995 |
Is potassium channel opening an effective form of preconditioning before cardioplegia?
Topics: Analysis of Variance; Animals; Blood Pressure; Cardiac Volume; Cardioplegic Solutions; Coronary Circ | 1996 |
Different responses of epicardium and endocardium to KATP channel modulators during regional ischemia.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Decanoic Acids; Dogs; Endocardium; Hydroxy Acids | 1996 |
Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Dogs; E | 1996 |
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiaze | 1996 |
Mechanisms of action of various ATP-sensitive potassium channel openers.
Topics: Adenosine Triphosphate; Animals; Dogs; Ion Channel Gating; Myocardial Ischemia; Niacinamide; Nicoran | 1996 |
Role of activation of ectosolic 5'-nucleotidase in the cardioprotection mediated by opening of K+c channels.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Enzyme Activation; | 1996 |
[Potassium channel activators: hemodynamic effects at the systemic and coronary level].
Topics: Animals; Coronary Circulation; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; P | 1995 |
[Successful treatment of intraoperative myocardial ischemia with nicorandil].
Topics: Aged; Aged, 80 and over; Anesthesia; Female; Humans; Injections, Intravenous; Intraoperative Complic | 1997 |
Pinacidil but not nicorandil opens ATP-sensitive K+ channels and protects against simulated ischemia in rabbit myocytes.
Topics: Adenosine Triphosphate; Animals; Cell Death; Disease Models, Animal; Electrophysiology; Female; Guan | 1997 |
Beneficial effect of concomitant administration of isoflurane and nicorandil.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Therapy, Co | 1997 |
Ventricular fibrillation in preconditioned pig hearts: role of K+ATP channels.
Topics: Action Potentials; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart; Heart Rate; Ischemic Pr | 1997 |
Differential role of epicardial and endocardial K(ATP) channels in potassium accumulation during regional ischemia induced by embolization of a coronary artery with latex.
Topics: Adenosine Triphosphate; Algorithms; Animals; Coronary Vessels; Dogs; Embolization, Therapeutic; Endo | 1998 |
The effects of nicorandil on electrophysiological changes in acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Drug Evaluation, Precl | 1998 |
Nicorandil attenuates myocardial dysfunction associated with transient ischemia by opening ATP-dependent potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Dogs; Female; | 1992 |
Evolving Issues in the Treatment of Angina Pectoris. Nicorandil: The 1st Potassium-Channel Activator in Ischemic Heart Disease. Proceedings of an International Workshop. Taormina, Sicily, May 8-12, 1991.
Topics: Animals; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels | 1992 |