niacinamide has been researched along with Myeloproliferative Disorders in 7 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast to BCR-ABL-positive chronic myelogenous leukemia, only few cases of imatinib resistance and mutations of the FP kinase domain have been described so far." | 1.37 | The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. ( Aberg, E; Duyster, J; Engh, RA; Gorantla, SP; Oliveira, TM; Peschel, C; Thöne, S; von Bubnoff, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Xicoy, B | 1 |
| Zamora, L | 1 |
| Barrio, S | 1 |
| Gallardo, M | 1 |
| Arenas, A | 1 |
| Ayala, R | 1 |
| Rapado, I | 1 |
| Rueda, D | 1 |
| Jiménez-Ubieto, A | 1 |
| Albizua, E | 1 |
| Burgaleta, C | 1 |
| Gilsanz, F | 1 |
| Martinez-Lopez, J | 1 |
| Falchi, L | 1 |
| Mehrotra, M | 1 |
| Newberry, KJ | 1 |
| Lyle, LM | 1 |
| Lu, G | 1 |
| Patel, KP | 1 |
| Luthra, R | 1 |
| Popat, U | 1 |
| Verstovsek, S | 1 |
| Lim, Y | 1 |
| Gondek, L | 1 |
| Li, L | 1 |
| Wang, Q | 1 |
| Ma, H | 2 |
| Chang, E | 1 |
| Huso, DL | 1 |
| Foerster, S | 1 |
| Marchionni, L | 1 |
| McGovern, K | 1 |
| Watkins, DN | 1 |
| Peacock, CD | 1 |
| Levis, M | 1 |
| Smith, BD | 1 |
| Merchant, AA | 1 |
| Small, D | 1 |
| Matsui, W | 1 |
| Cully, M | 1 |
| von Bubnoff, N | 1 |
| Gorantla, SP | 1 |
| Engh, RA | 1 |
| Oliveira, TM | 1 |
| Thöne, S | 1 |
| Aberg, E | 1 |
| Peschel, C | 1 |
| Duyster, J | 1 |
| Wakim, JJ | 1 |
| Tirado, CA | 1 |
| Chen, W | 1 |
| Collins, R | 1 |
2 reviews available for niacinamide and Myeloproliferative Disorders
| Article | Year |
|---|---|
Trial watch: Telomerase inhibitor shows promise in myeloproliferative disorders.
Topics: Animals; Clinical Trials, Phase II as Topic; Enzyme Inhibitors; Humans; Indoles; Myeloproliferative | 2015 |
t(8;22)/BCR-FGFR1 myeloproliferative disorder presenting as B-acute lymphoblastic leukemia: report of a case treated with sorafenib and review of the literature.
Topics: Antineoplastic Agents; Benzenesulfonates; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 8; D | 2011 |
5 other studies available for niacinamide and Myeloproliferative Disorders
| Article | Year |
|---|---|
Current treatment of myeloproliferative neoplasias: three scenarios.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; Leukemia, Myelogenous, | 2020 |
Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm.
Topics: Adult; Aged; Aged, 80 and over; Benzhydryl Compounds; Cell Proliferation; Cells, Cultured; Chronic D | 2013 |
ETV6-FLT3 fusion gene-positive, eosinophilia-associated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplant.
Topics: Adult; Cytogenetics; Eosinophilia; ETS Translocation Variant 6 Protein; Female; fms-Like Tyrosine Ki | 2014 |
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.
Topics: Animals; Cell Compartmentation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progres | 2015 |
The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro.
Topics: Amino Acid Sequence; Antineoplastic Agents; Benzamides; Benzenesulfonates; Blotting, Western; Cell L | 2011 |