niacinamide has been researched along with Medulloblastoma in 4 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medulloblastoma is the most common brain tumor in children." | 5.38 | Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor. ( Buettner, R; Chang, S; Hedvat, M; Jove, R; Jove, V; Liu, L; Scuto, A; Tian, Y; Van Meter, T; Wen, W; Yang, F; Yen, Y; Yip, ML, 2012) |
| "Medulloblastomas are the most frequent malignant brain tumors in children." | 5.35 | Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas. ( Buettner, R; Chen, MY; Hedvat, M; Jove, R; Kirschbaum, M; Kowolik, CM; Liang, W; Mepani, N; Mirosevich, J; Nam, S; Tye, G; Van Meter, TE; Yang, F, 2008) |
| "Medulloblastoma is a primitive neuroectodermal tumor, which originates in the cerebellum, presumably due to the alterations of some neurogenetic elements." | 1.39 | Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro. ( Chen, XM; Kong, QY; Li, H; Li, ZX; Liu, J; Ma, JX; Wang, Q; Wu, ML; Yang, XH, 2013) |
| "Medulloblastoma is the most common brain tumor in children." | 1.38 | Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor. ( Buettner, R; Chang, S; Hedvat, M; Jove, R; Jove, V; Liu, L; Scuto, A; Tian, Y; Van Meter, T; Wen, W; Yang, F; Yen, Y; Yip, ML, 2012) |
| "Medulloblastomas are the most frequent malignant brain tumors in children." | 1.35 | Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas. ( Buettner, R; Chen, MY; Hedvat, M; Jove, R; Kirschbaum, M; Kowolik, CM; Liang, W; Mepani, N; Mirosevich, J; Nam, S; Tye, G; Van Meter, TE; Yang, F, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Craveiro, RB | 1 |
| Ehrhardt, M | 1 |
| Holst, MI | 1 |
| Pietsch, T | 1 |
| Dilloo, D | 1 |
| Yang, F | 2 |
| Van Meter, TE | 1 |
| Buettner, R | 2 |
| Hedvat, M | 2 |
| Liang, W | 1 |
| Kowolik, CM | 1 |
| Mepani, N | 1 |
| Mirosevich, J | 1 |
| Nam, S | 1 |
| Chen, MY | 1 |
| Tye, G | 1 |
| Kirschbaum, M | 1 |
| Jove, R | 2 |
| Jove, V | 1 |
| Chang, S | 1 |
| Liu, L | 1 |
| Tian, Y | 1 |
| Scuto, A | 1 |
| Wen, W | 1 |
| Yip, ML | 1 |
| Van Meter, T | 1 |
| Yen, Y | 1 |
| Ma, JX | 1 |
| Li, H | 1 |
| Chen, XM | 1 |
| Yang, XH | 1 |
| Wang, Q | 1 |
| Wu, ML | 1 |
| Kong, QY | 1 |
| Li, ZX | 1 |
| Liu, J | 1 |
4 other studies available for niacinamide and Medulloblastoma
| Article | Year |
|---|---|
In comparative analysis of multi-kinase inhibitors for targeted medulloblastoma therapy pazopanib exhibits promising in vitro and in vivo efficacy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Movement; Cell Proli | 2014 |
Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Cell Cycle; Cell Line, Tumor; Cell Pro | 2008 |
Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Kille | 2012 |
Expression patterns and potential roles of SIRT1 in human medulloblastoma cells in vivo and in vitro.
Topics: Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cerebellar Neoplasms; Cerebellum; Hum | 2013 |