Page last updated: 2024-10-19

niacinamide and MODS

niacinamide has been researched along with MODS in 4 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
" In vivo treatment with ip administration of 3-aminobenzamide (10 mg/kg, 1 and 6 hrs after zymosan injection) or nicotinamide (50 mg/kg, 1 and 6 hrs after zymosan injection) significantly decreased mortality, inhibited the development of peritonitis, and reduced peroxynitrite formation."3.70Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S; Sottile, A; Teti, D; Zingarelli, B, 1999)
"Sepsis is a common clinical critical disease, which is one of the main causes of septic shock and multiple organ dysfunction syndrome (MODS)."1.56[Progress of nicotinamide in preventing infection and sepsis]. ( Chen, T; Cheng, L; Liang, H; Liu, K; Liu, Y, 2020)
"Sepsis-caused multiple organ failure remains the major cause of morbidity and mortality in intensive care units."1.48Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis. ( Fan, GC; Hong, G; Lu, Z; Ni, R; Peng, T; Wang, G; Zhang, L; Zheng, D, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Cheng, L1
Chen, T1
Liu, Y1
Liu, K1
Liang, H1
Hong, G1
Zheng, D1
Zhang, L1
Ni, R1
Wang, G1
Fan, GC1
Lu, Z1
Peng, T1
Wray, GM1
Hinds, CJ1
Thiemermann, C1
Cuzzocrea, S1
Zingarelli, B1
Costantino, G1
Sottile, A1
Teti, D1
Caputi, AP1

Other Studies

4 other studies available for niacinamide and MODS

ArticleYear
[Progress of nicotinamide in preventing infection and sepsis].
    Zhonghua wei zhong bing ji jiu yi xue, 2020, Volume: 32, Issue:7

    Topics: Humans; Multiple Organ Failure; Niacinamide; Poly(ADP-ribose) Polymerases; Sepsis; Shock, Septic; Vi

2020
Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis.
    Free radical biology & medicine, 2018, 08-01, Volume: 123

    Topics: Animals; Apoptosis; Disease Models, Animal; HMGB1 Protein; Lipopolysaccharides; Macrophages; Male; M

2018
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
    Shock (Augusta, Ga.), 1998, Volume: 10, Issue:1

    Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne

1998
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
    Critical care medicine, 1999, Volume: 27, Issue:8

    Topics: Animals; Benzamides; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Multip

1999