niacinamide has been researched along with MODS in 4 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vivo treatment with ip administration of 3-aminobenzamide (10 mg/kg, 1 and 6 hrs after zymosan injection) or nicotinamide (50 mg/kg, 1 and 6 hrs after zymosan injection) significantly decreased mortality, inhibited the development of peritonitis, and reduced peroxynitrite formation." | 3.70 | Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat. ( Caputi, AP; Costantino, G; Cuzzocrea, S; Sottile, A; Teti, D; Zingarelli, B, 1999) |
| "Sepsis is a common clinical critical disease, which is one of the main causes of septic shock and multiple organ dysfunction syndrome (MODS)." | 1.56 | [Progress of nicotinamide in preventing infection and sepsis]. ( Chen, T; Cheng, L; Liang, H; Liu, K; Liu, Y, 2020) |
| "Sepsis-caused multiple organ failure remains the major cause of morbidity and mortality in intensive care units." | 1.48 | Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis. ( Fan, GC; Hong, G; Lu, Z; Ni, R; Peng, T; Wang, G; Zhang, L; Zheng, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, L | 1 |
| Chen, T | 1 |
| Liu, Y | 1 |
| Liu, K | 1 |
| Liang, H | 1 |
| Hong, G | 1 |
| Zheng, D | 1 |
| Zhang, L | 1 |
| Ni, R | 1 |
| Wang, G | 1 |
| Fan, GC | 1 |
| Lu, Z | 1 |
| Peng, T | 1 |
| Wray, GM | 1 |
| Hinds, CJ | 1 |
| Thiemermann, C | 1 |
| Cuzzocrea, S | 1 |
| Zingarelli, B | 1 |
| Costantino, G | 1 |
| Sottile, A | 1 |
| Teti, D | 1 |
| Caputi, AP | 1 |
4 other studies available for niacinamide and MODS
| Article | Year |
|---|---|
[Progress of nicotinamide in preventing infection and sepsis].
Topics: Humans; Multiple Organ Failure; Niacinamide; Poly(ADP-ribose) Polymerases; Sepsis; Shock, Septic; Vi | 2020 |
Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis.
Topics: Animals; Apoptosis; Disease Models, Animal; HMGB1 Protein; Lipopolysaccharides; Macrophages; Male; M | 2018 |
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne | 1998 |
Protective effect of poly(ADP-ribose) synthetase inhibition on multiple organ failure after zymosan-induced peritonitis in the rat.
Topics: Animals; Benzamides; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Multip | 1999 |