niacinamide has been researched along with MELAS Syndrome in 4 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Klaidman, LK | 1 |
| Adams, JD | 1 |
| Majamaa, K | 2 |
| Rusanen, H | 2 |
| Remes, AM | 1 |
| Pyhtinen, J | 1 |
| Hassinen, IE | 2 |
| Remes, A | 1 |
| Penn, AM | 1 |
| Lee, JW | 1 |
| Thuillier, P | 1 |
| Wagner, M | 1 |
| Maclure, KM | 1 |
| Menard, MR | 1 |
| Hall, LD | 1 |
| Kennaway, NG | 1 |
1 review available for niacinamide and MELAS Syndrome
| Article | Year |
|---|---|
Medicinal chemistry of nicotinamide in the treatment of ischemia and reperfusion.
Topics: Animals; Humans; Ischemia; MELAS Syndrome; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Poly | 2002 |
3 other studies available for niacinamide and MELAS Syndrome
| Article | Year |
|---|---|
Increase of blood NAD+ and attenuation of lactacidemia during nicotinamide treatment of a patient with the MELAS syndrome.
Topics: Aged; Anticonvulsants; Carbamazepine; Cells, Cultured; Cerebrovascular Disorders; Epilepsy; Fibrobla | 1996 |
Metabolic interventions against complex I deficiency in MELAS syndrome.
Topics: Administration, Oral; Adult; DNA, Mitochondrial; Humans; Male; MELAS Syndrome; Mitochondria, Muscle; | 1997 |
MELAS syndrome with mitochondrial tRNA(Leu)(UUR) mutation: correlation of clinical state, nerve conduction, and muscle 31P magnetic resonance spectroscopy during treatment with nicotinamide and riboflavin.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Spectroscopy; MELAS Syndrome; M | 1992 |