niacinamide has been researched along with Liver Diseases in 56 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In PC2-defective cells, sorafenib inhibits B-Raf but paradoxically activates Raf-1, resulting in increased ERK1/2 phosphorylation, cell proliferation, and cyst growth in vivo." | 7.78 | Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib. ( Fabris, L; Ferrero, C; Fiorotto, R; Kim, AK; Locatelli, L; Morell, CM; Okolicsanyi, S; Spirli, C; Strazzabosco, M, 2012) |
| "HPS (hepatopulmonary syndrome) is characterized by oxygen desaturation in patients with chronic liver disease." | 5.39 | Sorafenib treatment improves hepatopulmonary syndrome in rats with biliary cirrhosis. ( Chang, CC; Chuang, CL; Hsieh, HG; Hsu, SJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2013) |
| "In PC2-defective cells, sorafenib inhibits B-Raf but paradoxically activates Raf-1, resulting in increased ERK1/2 phosphorylation, cell proliferation, and cyst growth in vivo." | 3.78 | Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib. ( Fabris, L; Ferrero, C; Fiorotto, R; Kim, AK; Locatelli, L; Morell, CM; Okolicsanyi, S; Spirli, C; Strazzabosco, M, 2012) |
| " The impact of hepatic impairment on the peficitinib pharmacokinetic (PK) and safety profile was investigated in non-RA subjects (n = 24) in an open-label, parallel-group, multicenter comparative study in Japan." | 1.56 | Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function. ( Furihata, K; Inoue, K; Ito, T; Kaneko, Y; Katashima, M; Miyatake, D; Nishimura, T; Oda, K; Sakaki, M; Shibata, T; Toyoshima, J; Uchida, N; Urae, A, 2020) |
| "HPS (hepatopulmonary syndrome) is characterized by oxygen desaturation in patients with chronic liver disease." | 1.39 | Sorafenib treatment improves hepatopulmonary syndrome in rats with biliary cirrhosis. ( Chang, CC; Chuang, CL; Hsieh, HG; Hsu, SJ; Huang, HC; Lee, FY; Lee, SD; Lin, HC; Teng, TH; Wang, SS, 2013) |
| " We have developed a mouse model to demonstrate the toxic effects of methotrexate: mice were given 50 mg/kg acetaminophen, which itself has no effect on the liver." | 1.30 | Nicotinamide and methionine reduce the liver toxic effect of methotrexate. ( Bache, K; Hauschild, A; Kröger, H; Krüger, D; Ohde, M; Thefeldt, W; Voigt, WP, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (80.36) | 18.7374 |
| 1990's | 3 (5.36) | 18.2507 |
| 2000's | 1 (1.79) | 29.6817 |
| 2010's | 6 (10.71) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Sambeat, A | 1 |
| Ratajczak, J | 1 |
| Joffraud, M | 1 |
| Sanchez-Garcia, JL | 1 |
| Giner, MP | 1 |
| Valsesia, A | 1 |
| Giroud-Gerbetant, J | 1 |
| Valera-Alberni, M | 1 |
| Cercillieux, A | 1 |
| Boutant, M | 1 |
| Kulkarni, SS | 1 |
| Moco, S | 1 |
| Canto, C | 1 |
| Miyatake, D | 1 |
| Shibata, T | 1 |
| Toyoshima, J | 1 |
| Kaneko, Y | 1 |
| Oda, K | 1 |
| Nishimura, T | 1 |
| Katashima, M | 1 |
| Sakaki, M | 1 |
| Inoue, K | 1 |
| Ito, T | 1 |
| Uchida, N | 1 |
| Furihata, K | 1 |
| Urae, A | 1 |
| Romantsov, MG | 1 |
| Petrov, AIu | 1 |
| Aleksandrova, LN | 1 |
| Sukhanov, DS | 1 |
| Kovalenko, AL | 1 |
| Pár, A | 1 |
| Pár, G | 1 |
| ARCHI, G | 1 |
| TINACCI, F | 1 |
| MESSINA, R | 1 |
| Toonen, F | 1 |
| Smilde, T | 1 |
| Khodosovskiĭ, MN | 1 |
| Zinchuk, VV | 1 |
| Chlopicki, S | 1 |
| Spirli, C | 1 |
| Morell, CM | 1 |
| Locatelli, L | 1 |
| Okolicsanyi, S | 1 |
| Ferrero, C | 1 |
| Kim, AK | 1 |
| Fabris, L | 1 |
| Fiorotto, R | 1 |
| Strazzabosco, M | 1 |
| Chang, CC | 1 |
| Chuang, CL | 1 |
| Lee, FY | 1 |
| Wang, SS | 1 |
| Lin, HC | 1 |
| Huang, HC | 1 |
| Teng, TH | 1 |
| Hsu, SJ | 1 |
| Hsieh, HG | 1 |
| Lee, SD | 1 |
| INDOVINA, I | 1 |
| CAUSI, N | 1 |
| BARBIERI, LL | 2 |
| BOSELLI, A | 2 |
| NOCCA, G | 1 |
| CAGIANELLI, MA | 1 |
| SPREMOLLA, G | 1 |
| PIERI, N | 1 |
| MARIANI, B | 1 |
| DE SIMONI, G | 1 |
| BOCCITTO, G | 1 |
| ESPOSITO, S | 1 |
| NICROSINI, F | 1 |
| PETRONIO, L | 1 |
| CALABRESE, L | 1 |
| BERTI, P | 1 |
| CAZZOLA, D | 1 |
| DRAGO, U | 2 |
| FINOTTO, E | 2 |
| MADDALOSSO, T | 1 |
| LOTTI, F | 1 |
| ROSA, L | 1 |
| Hirayama, C | 1 |
| Ichida, F | 1 |
| Takahashi, Y | 1 |
| Koizumi, T | 1 |
| Sato, S | 1 |
| Kosaka, Y | 1 |
| Wakui, K | 1 |
| Shimada, Y | 1 |
| Yoshiba, A | 1 |
| Hattori, N | 1 |
| Ooya, T | 1 |
| Takino, T | 1 |
| Takeda, H | 1 |
| Nomura, F | 1 |
| Takashima, H | 1 |
| Itoga, S | 1 |
| Isobe, K | 1 |
| Takekoshi, K | 1 |
| Noda, M | 1 |
| Nakai, T | 1 |
| Kröger, H | 1 |
| Hauschild, A | 1 |
| Ohde, M | 1 |
| Bache, K | 1 |
| Voigt, WP | 1 |
| Thefeldt, W | 1 |
| Krüger, D | 1 |
| McDonald, MC | 1 |
| Filipe, HM | 1 |
| Thiemermann, C | 1 |
| Hirsch, W | 1 |
| Smerlings, H | 1 |
| Chiancone, FM | 1 |
| Căruntu, V | 1 |
| Voiculescu, M | 1 |
| Perederi, L | 1 |
| Roşca, M | 1 |
| Dună, F | 1 |
| Olivieri, V | 1 |
| Mauro, V | 1 |
| Bazzicalupo, G | 1 |
| Pietranera, P | 2 |
| Ongaro, G | 1 |
| Meneghini, P | 1 |
| Avanzi, G | 1 |
| Rossini, A | 1 |
| Merlini, R | 1 |
| Ivaldi, A | 1 |
| Miracco, A | 1 |
| Orlando, V | 1 |
| Di Lorenzo, S | 1 |
| Piro, E | 1 |
| Nicoletti, A | 1 |
| Ruffolo, S | 1 |
| Floris, E | 1 |
| Mura, B | 1 |
| Heirwegh, KP | 1 |
| Ramboer, C | 1 |
| De Groote, J | 1 |
| De Martiis, M | 1 |
| Di Blasi, S | 1 |
| Pintacuda, S | 1 |
| Di Blasi, G | 1 |
| Cairella, M | 2 |
| Piva, M | 1 |
| Ongari, R | 1 |
| Fanelli, V | 1 |
| Rossi, L | 1 |
| Laghi, V | 1 |
| Cavallaro, A | 1 |
| Skakun, MP | 1 |
| Budillon, G | 1 |
| Carrella, M | 1 |
| Oriani, G | 1 |
| Venditti, A | 1 |
| Piazza, E | 1 |
| Sindoni, G | 1 |
| Stornello, C | 1 |
| Foti, V | 1 |
| Kanagawa, H | 1 |
| Gniwotta, E | 1 |
| Kirchdorfer, AM | 1 |
| Winter, SL | 1 |
| Boyer, JL | 1 |
3 reviews available for niacinamide and Liver Diseases
| Article | Year |
|---|---|
[Pathogenetic correction of metabolic disturbances in chronic liver affections].
Topics: Apoptosis; Chronic Disease; Drug Combinations; Flavin Mononucleotide; Glutathione Disulfide; Hepatit | 2012 |
[On the so-called hepatoprotective drugs. II. The so-called hepatoprotective drugs in the treatment of liver diseases].
Topics: Androgens; Cytochromes; Glutamates; Humans; Lipotropic Agents; Liver Diseases; Liver Extracts; Niaci | 1967 |
[Choleretics of synthetic and plant origin].
Topics: Animals; Biliary Tract Diseases; Cholagogues and Choleretics; Dehydrocholic Acid; Guinea Pigs; Human | 1968 |
3 trials available for niacinamide and Liver Diseases
| Article | Year |
|---|---|
A controlled clinical trial of nicotinohydroxamic acid and neomycin in advanced chronic liver disease.
Topics: Ammonia; Chronic Disease; Clinical Trials as Topic; Electroencephalography; Female; Humans; Liver Di | 1982 |
[Drug therapy of liver diseases with Hepatofalk].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cysteine; Drug Combinations; Female; Folic Acid; | 1976 |
[Treatment of various liver diseases with a liver-drug combination composed of essential amino acids, vitamin B, folic acid and nicotinamide].
Topics: Adult; Aged; Amino Acids; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; | 1973 |
50 other studies available for niacinamide and Liver Diseases
| Article | Year |
|---|---|
Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage.
Topics: Animals; Blood Glucose; Diet, High-Fat; Disease Models, Animal; DNA Damage; Gene Knockout Techniques | 2019 |
Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function.
Topics: Adamantane; Administration, Oral; Aged; Area Under Curve; Asian People; Female; Humans; Janus Kinase | 2020 |
[The 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), Milan, Italy, April 23-27, 2008].
Topics: Antineoplastic Agents; Antiviral Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Clinical Tria | 2008 |
On the action of nicotinic amide in the liver due to stasis (heart failure).
Topics: Heart Failure; Liver Diseases; Niacin; Niacinamide | 1948 |
The influence of vitamin PP on the exchange of creatine and creatinine in some morbid conditions; behavior of creatine and creatinine in hepatopatients.
Topics: Creatine; Liver Diseases; Niacinamide; Nutrition Therapy | 1948 |
A retroperitoneal mass with elevated alpha-1-fetoprotein: not always a testicular carcinoma.
Topics: alpha-Fetoproteins; Antineoplastic Agents; Benzenesulfonates; Biopsy; Carcinoma, Hepatocellular; Cho | 2010 |
[Effect of 1-methylnicotinamide on prooxidant-antioxidant balance parameters in rats during hepatic ischemia-reperfusion].
Topics: Animals; Antioxidants; Liver; Liver Diseases; Male; Niacinamide; Rats; Rats, Wistar; Reperfusion Inj | 2010 |
Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib.
Topics: Animals; Antineoplastic Agents, Hormonal; Benzenesulfonates; Bile Ducts; Caspase 3; Cell Proliferati | 2012 |
Sorafenib treatment improves hepatopulmonary syndrome in rats with biliary cirrhosis.
Topics: Animals; Benzenesulfonates; Common Bile Duct; Disease Models, Animal; Hemodynamics; Hepatopulmonary | 2013 |
[Metabolism of nicotinamide in man. III. Venous tolerance test in liver disease, blood disease, circulatory insufficiency and other morbid conditions].
Topics: Hematologic Diseases; Liver Diseases; Niacin; Niacinamide; Veins | 1952 |
[Effect of nicotinamide overload on riboflavinuria in subjects without liver lesions and in liver disease patients].
Topics: Body Fluids; Gastrointestinal Diseases; Humans; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids | 1954 |
[Necessary supplementation of vitamin B12 with folic acid, ascorbic acid and nicotinamide for purposes of liver protection; posological and therapeutic study].
Topics: Ascorbic Acid; Folic Acid; Humans; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids; Vitamin B 1 | 1958 |
[Therapy of liver diseases with high protein dit & vitamin B12 combined with folic acid, vitamin PP & vitamin C].
Topics: Ascorbic Acid; Corrinoids; Folic Acid; Humans; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids; | 1959 |
[Effects of vitamin B-12 alone and associated with folic acid, vitamin C and vitamin PP on hepatic lesions and on humoral behavior in the course of chronic poisoning with carbon tetrachloride. Experimental research].
Topics: Ascorbic Acid; Carbon Tetrachloride; Chronic Disease; Folic Acid; Humans; Liver Diseases; Niacinamid | 1961 |
[Contribution to the treatment of hepatopathic manifestations in the course of tuberculosis with combined vitamin B12, folic acid, vitamin C and vitamin PP].
Topics: Ascorbic Acid; Folic Acid; Humans; Liver Diseases; Niacinamide; Tuberculosis; Vitamin B 12; Vitamin | 1961 |
[The nature and prevention of hepatic steatosis caused by massive doses of nicotinamide and 6-aminonicotinamide].
Topics: 6-Aminonicotinamide; Fatty Liver; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids | 1959 |
[Clinical study of a new compound with choleretic and liver-protective action].
Topics: Cholagogues and Choleretics; Cholecystectomy; Cholecystitis; Dyspepsia; Hepatitis; Humans; Liver Dis | 1962 |
[On the treatment of the premenstrual syndrome and menstruation disorders by means of hepatic therapy].
Topics: Cysteine; Female; Gluconates; Humans; Liver Diseases; Liver Extracts; Menstruation Disturbances; Met | 1963 |
[CONSIDERATIONS ON THE USE OF CYANOCOBALAMINE IN HIGH DOSES BY PHLEBOCLYSIS (ASSOCIATED WITH PP VITAMIN, ASCORBIC ACID, FOLIC ACID) IN VARIOUS CLINICAL SITUATIONS (LIVER DISEASES, ANEMIC-DEFICIENT SYNDROMES)].
Topics: Adolescent; Anemia; Ascorbic Acid; Child; Corrinoids; Folic Acid; Geriatrics; Humans; Injections, In | 1965 |
On the action of high doses of vitamin B 12 combined with folic acid, vitamin PP and ascorbic acid in treatment of infantile liver diseases
Topics: Ascorbic Acid; Child; Corrinoids; Folic Acid; Infant; Liver Diseases; Niacin; Niacinamide; Nicotinic | 1959 |
[Urinary elimination of thiamine under nicotinamide load in subjects with and without hepatic diseases].
Topics: Liver Diseases; Niacin; Niacinamide; Nicotinic Acids; Thiamine | 1950 |
Serum NAD glycohydrolase activities in normal subjects and in patients with chronic liver diseases.
Topics: Adolescent; Adult; Aged; Carbon Radioisotopes; Chronic Disease; Female; Humans; Kinetics; Liver Dise | 1997 |
Nicotinamide and methionine reduce the liver toxic effect of methotrexate.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antirheumatic Agents; Aspart | 1999 |
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Blood Pressure; Creatine Kin | 1999 |
[Notes for a study on vitaminology in Italy].
Topics: Beriberi; Heart; Hemoptysis; History, 20th Century; Humans; Italy; Liver Diseases; Niacinamide; Nico | 1979 |
[The product "Essentiale" in therapy of acute epidemic hepatitis].
Topics: Blood Protein Electrophoresis; Drug Combinations; Evaluation Studies as Topic; Fatty Acids, Nonester | 1973 |
[The influence of a new hepato-protective agent and detoxicant on pre-renal, renal and post-renal hyperazotemia].
Topics: Adolescent; Adult; Aged; Blood; Child; Female; Humans; Lipotropic Agents; Liver Diseases; Male; Midd | 1966 |
[On a combination of amino acids and vitamins in the treatment of liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Orn | 1967 |
[Clinical observations on the therapeutic efficiency of the combination: arginine HCl, citrulline, ornithine HCl, vitamin B-12, folic acid and nicotinamide in liver diseases and in anemic deficiency syndromes].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Niacinamid | 1967 |
[On the therapeutic value of some amino acids in combination with vitamin B 12, folic acid and nicotinamide in the therapy of hepatic insufficiency].
Topics: Adolescent; Adult; Aged; Arginine; Biliary Tract Diseases; Citrulline; Female; Folic Acid; Humans; L | 1967 |
[Clinical experimentation with a new pharmacologic combination having a liver protective and detoxicant scope].
Topics: Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Niacinamide; Ornithine; Vita | 1967 |
[Clinical cases on the use of a combination of substances with hepatoprotective and detoxicant action in the treatment of some acute and chronic liver diseases].
Topics: Adolescent; Adult; Aged; Arginine; Child; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Ma | 1967 |
[Association of vitamins and amino acids in the therapy of chronic liver diseases. Clinical results].
Topics: Adolescent; Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Mid | 1967 |
[Clinical considerations on the use of a new preparation with hepatoprotective action].
Topics: Adult; Aged; Arginine; Citrulline; Female; Folic Acid; Humans; Liver Diseases; Male; Middle Aged; Ni | 1967 |
[Clinico-metabolic observations on the use in therapy of a combination of vitamin B-12, folic acid, nicotinamide and amino acids of the arginine group in patients with chronic liver diseases].
Topics: Adult; Aged; Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Middle Aged; Niacinamide; Orn | 1967 |
[Clinical experimentation with a new preparation: Polilevo].
Topics: Arginine; Citrulline; Folic Acid; Humans; Liver Diseases; Niacinamide; Ornithine; Vitamin B 12 | 1967 |
Purine and pyrimidine excretion. I. Chromatographic separation and identification of purine and pyrimidine metabolites in human urine.
Topics: Adenine; Chromatography; Chromatography, Paper; Creatine; Diet; Humans; Hypoxanthines; Liver Disease | 1967 |
[Clinical study of a new drug association with a base of nucleosides in therapy of some liver diseases].
Topics: Adult; Aged; Amino Acids; Cholelithiasis; Female; Folic Acid; Humans; Liver Diseases; Male; Middle A | 1966 |
A proposito di terapia epatotropa.
Topics: Adult; Amino Acids; Carbon Tetrachloride Poisoning; Cholecystitis; Cholelithiasis; Female; Folic Aci | 1968 |
[Clinical evaluation of a new preparation with liver-protective and anti-anemic action].
Topics: Adolescent; Adult; Aged; Anemia; Choline; Female; Folic Acid; Hemochromatosis; Humans; Hydroxybutyra | 1966 |
[Considerations on the clinical use of a new association of drugs in the treatment of hepatopathies].
Topics: Adolescent; Adult; Aged; Humans; Leucovorin; Liver Diseases; Methionine; Middle Aged; Niacinamide; N | 1968 |
[Clinical observations on a new preparation with hepatoprotective action].
Topics: Adult; Aged; Amino Acids; Arthritis, Rheumatoid; Biliary Dyskinesia; Dyspepsia; Female; Folic Acid; | 1967 |
[Research on the hepatoprotective effect of 1-amino acids involved in the Krebs-Henseleit cycle associated with vitamins].
Topics: Aged; Amino Acids; Bilirubin; Female; Folic Acid; Humans; Liver Diseases; Liver Function Tests; Male | 1968 |
[Evaluation of some tolerance tests for liver functional investigations].
Topics: Aminobenzoates; Benzoates; Glucuronates; Humans; Liver Diseases; Liver Function Tests; Niacinamide | 1969 |
[A new hepatoprotective preparation. Biochemical aspects and clinical studies].
Topics: Adult; Aged; Animals; Biopsy; Drug Synergism; Female; Folic Acid; Humans; Liver; Liver Diseases; Mal | 1968 |
[Clinical observations on the activity of phosphatidylcholine, thiamine, riboflavin and nicotinamide in chronic liver diseases].
Topics: Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Niacinamide; Phosph | 1969 |
[Therapeutic value of an association of phospholipids and adrenal cortex in hepatology].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adult; Aged; Asthenia; Biliary Tract Diseases; | 1971 |
[Clinico-therapeutic evaluation of a new drug combination with hepatotrophic effect].
Topics: Adenine; Adult; Child; Drug Combinations; Folic Acid; Hepatitis A; Humans; Hydroxocobalamin; Inosine | 1972 |
2-Pyridone excretion after nicotinamide loading as a liver function test.
Topics: Adult; Aged; Bilirubin; Female; Humans; Liver Diseases; Liver Function Tests; Male; Middle Aged; Nia | 1972 |
Hepatic toxicity from large doses of vitamin B3 (nicotinamide).
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Biopsy; Chemical and Drug Induc | 1973 |