niacinamide has been researched along with Leukemia, Myeloid in 14 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sorafenib is a small molecule inhibitor of RAF kinase, VEGFR-2, c-KIT, and FLT3." | 2.75 | A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study. ( Brandwein, J; Buckstein, R; Crump, M; Eisenhauer, E; Hedley, D; Kamel-Reid, S; Kassis, J; Leber, B; Matthews, J; McIntosh, L; Minden, M; Robinson, S; Seymour, L; Turner, R; Wells, R, 2010) |
| "Treatment with sorafenib/obatoclax induced pronounced apoptosis in and reduced the clonogenic growth of multiple AML lines and primary AML cells but not normal CD34(+) cells." | 1.38 | Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process. ( Attkisson, E; Aust, MM; Ferreira-Gonzalez, A; Grant, S; Rahmani, M; Williams, DC, 2012) |
| "Sorafenib response was associated with an inhibition of the antiapoptotic FLT3-ITD target Stat-5 in vivo." | 1.35 | Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation. ( Burchert, A; Chaturvedi, A; Eilers, M; Enghofer, E; Metzelder, S; Neubauer, A; Teichler, S; Wang, Y; Wanzel, M; Wollmer, E, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Kockerols, CCB | 1 |
| Janssen, JJWM | 1 |
| Blijlevens, NMA | 1 |
| Klein, SK | 1 |
| Van Hussen-Daenen, LGM | 1 |
| Van Gorkom, GGY | 1 |
| Smit, WM | 1 |
| Van Balen, P | 1 |
| Biemond, BJ | 1 |
| Cruijsen, MJ | 1 |
| Corsten, MF | 1 |
| Te Boekhorst, PAW | 1 |
| Koene, HR | 1 |
| Van Sluis, GL | 1 |
| Cornelissen, JJ | 1 |
| Westerweel, PE | 1 |
| Fernando, F | 1 |
| Innes, AJ | 1 |
| Claudiani, S | 1 |
| Pryce, A | 1 |
| Hayden, C | 1 |
| Byrne, J | 1 |
| Gallipoli, P | 1 |
| Copland, M | 1 |
| Apperley, JF | 1 |
| Milojkovic, D | 1 |
| Qiu, QC | 1 |
| Wang, C | 1 |
| Bao, XB | 1 |
| Yang, J | 1 |
| Shen, HJ | 1 |
| Ding, ZX | 1 |
| Liu, H | 1 |
| He, J | 1 |
| Yao, H | 1 |
| Chen, SN | 1 |
| Li, Z | 1 |
| Xue, SL | 1 |
| Liu, SB | 1 |
| Airiau, K | 1 |
| Prouzet-Mauléon, V | 1 |
| Rousseau, B | 1 |
| Pigneux, A | 1 |
| Jeanneteau, M | 1 |
| Giraudon, M | 1 |
| Allou, K | 1 |
| Dubus, P | 1 |
| Belloc, F | 1 |
| Mahon, FX | 1 |
| Metzelder, S | 1 |
| Wang, Y | 1 |
| Wollmer, E | 1 |
| Wanzel, M | 1 |
| Teichler, S | 1 |
| Chaturvedi, A | 1 |
| Eilers, M | 1 |
| Enghofer, E | 1 |
| Neubauer, A | 1 |
| Burchert, A | 1 |
| Tadmor, T | 1 |
| Tallman, MS | 1 |
| Polliack, A | 1 |
| Crump, M | 1 |
| Hedley, D | 1 |
| Kamel-Reid, S | 1 |
| Leber, B | 1 |
| Wells, R | 1 |
| Brandwein, J | 1 |
| Buckstein, R | 1 |
| Kassis, J | 1 |
| Minden, M | 1 |
| Matthews, J | 1 |
| Robinson, S | 1 |
| Turner, R | 1 |
| McIntosh, L | 1 |
| Eisenhauer, E | 1 |
| Seymour, L | 1 |
| Pardee, TS | 1 |
| Zuber, J | 1 |
| Lowe, SW | 1 |
| Rahmani, M | 1 |
| Aust, MM | 1 |
| Attkisson, E | 1 |
| Williams, DC | 1 |
| Ferreira-Gonzalez, A | 1 |
| Grant, S | 1 |
| IVANOVA, VD | 2 |
| RAUSHENBAKH, MO | 1 |
| EHRHART, H | 1 |
| SCHEFFEL, G | 1 |
| Auclair, D | 1 |
| Miller, D | 1 |
| Yatsula, V | 1 |
| Pickett, W | 1 |
| Carter, C | 1 |
| Chang, Y | 1 |
| Zhang, X | 1 |
| Wilkie, D | 1 |
| Burd, A | 1 |
| Shi, H | 1 |
| Rocks, S | 1 |
| Gedrich, R | 1 |
| Abriola, L | 1 |
| Vasavada, H | 1 |
| Lynch, M | 1 |
| Dumas, J | 1 |
| Trail, PA | 1 |
| Wilhelm, SM | 1 |
| Clemetson, KJ | 1 |
| Cherntsvoa, TA | 1 |
| Aksenova, OV | 1 |
1 trial available for niacinamide and Leukemia, Myeloid
| Article | Year |
|---|---|
A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study.
Topics: Abdominal Pain; Acute Disease; Adult; Aged; Aged, 80 and over; Area Under Curve; Benzenesulfonates; | 2010 |
13 other studies available for niacinamide and Leukemia, Myeloid
| Article | Year |
|---|---|
Treatment patterns and clinical outcomes of asciminib in a real-world multiresistant chronic myeloid leukemia patient population.
Topics: Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Niacinamide; Protein Ki | 2023 |
The outcome of post-transplant asciminib in patients with chronic myeloid leukaemia.
Topics: Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Niacinamide; Protein Ki | 2023 |
The impact of FLT3 mutations on treatment response and survival in Chinese de novo AML patients.
Topics: Acute Disease; Adult; Asian People; China; Drug Therapy; Female; fms-Like Tyrosine Kinase 3; Hematop | 2018 |
Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells.
Topics: Acute Disease; Aniline Compounds; Animals; Antineoplastic Agents; Antineoplastic Combined Chemothera | 2016 |
Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation.
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzene | 2009 |
Sorafenib - a small molecule with big promise?
Topics: Abdominal Pain; Acute Disease; Area Under Curve; Benzenesulfonates; Diarrhea; Dose-Response Relation | 2010 |
Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.
Topics: Acute Disease; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Blotting, | 2011 |
Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; B | 2012 |
[TRYPTOPHAN METABOLISM IN LEUKEMIA].
Topics: Anemia; Anemia, Aplastic; Chromatography; Drug Therapy; Hodgkin Disease; Humans; Indoles; Leukemia; | 1964 |
[STUDIES ON LEUKOCYTE METABOLISM. NICOTINAMIDE-ADENINE-DINUCLEOTIDE (NAD) CONTENT OF NORMAL AND LEUKEMIC LEUKOCYTES IN MAN. II].
Topics: Adenine; Blood Cell Count; Blood Chemical Analysis; Erythrocytes; Humans; Leukemia; Leukemia, Lympho | 1965 |
Antitumor activity of sorafenib in FLT3-driven leukemic cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Cell Cycle; Cell Line; Drug Screening | 2007 |
American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA.
Topics: Anemia, Sickle Cell; Antibiotics, Antineoplastic; Antigens, CD20; Benzamides; Benzenesulfonates; CD4 | 2007 |
[Apropos of the use of vitamins in the treatment of chronic leukemia at its early stage. II].
Topics: Ascorbic Acid; Chronic Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Niacinamide; Pyridoxi | 1966 |