Page last updated: 2024-10-19

niacinamide and Ischemia

niacinamide has been researched along with Ischemia in 19 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with nicorandil (30-100 micrograms kg-1) accelerated the recovery of PSR potentials after spinal cord ischaemia."1.29Effects of nicorandil on the recovery of reflex potentials after spinal cord ischaemia in cats. ( Moriya, H; Nakaya, H; Nemoto, T; Sekikawa, T; Suzuki, T, 1995)
"Hypoxia and ischemia are potent stimuli to vascular growth."1.28Angiogenic potency of nucleotide metabolites: potential role in ischemia-induced vascular growth. ( Ellis, MN; Morris, PB; Swain, JL, 1989)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's4 (21.05)18.2507
2000's4 (21.05)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferraris, DV1
Hosseini, L1
Vafaee, MS1
Mahmoudi, J1
Badalzadeh, R1
Yan, H1
Jihong, Y1
Feng, Z1
Xiaomei, X1
Xiaohan, Z1
Guangzhi, W1
Zhenhai, M1
Dongyan, G1
Xiaochi, M1
Qing, F1
Kexin, L1
Xiaofeng, T1
Tran, MT1
Zsengeller, ZK1
Berg, AH1
Khankin, EV1
Bhasin, MK1
Kim, W1
Clish, CB1
Stillman, IE1
Karumanchi, SA1
Rhee, EP1
Parikh, SM1
Wang, P1
Yang, X1
Zhang, Z1
Song, J1
Guan, YF1
Zou, DJ1
Miao, CY1
Zarubina, IV1
Yunusov, IA1
Marysheva, VV1
Shabanov, PD1
Yang, J1
Klaidman, LK1
Adams, JD1
Tam, D1
Tam, M1
Maynard, KI1
Su, CF1
Liu, DD1
Kao, SJ1
Chen, HI1
Warnick, CT1
Lazarus, HM1
Benedini, F1
Bertolini, G1
Cereda, R1
Donà, G1
Gromo, G1
Levi, S1
Mizrahi, J1
Sala, A1
Suzuki, T1
Sekikawa, T1
Nemoto, T1
Moriya, H1
Nakaya, H1
McDonald, MC1
Filipe, HM1
Thiemermann, C2
Ishibashi, T1
Matsubara, T1
Nakazawa, M1
Katsumata, N1
Imai, S1
Morris, PB1
Ellis, MN1
Swain, JL1
Kauffman, FC1
Johnson, EC1
Keller, K1
Kolbe, H1
Lange, K2
Herken, H1
Proft, ER1

Reviews

3 reviews available for niacinamide and Ischemia

ArticleYear
Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.
    Journal of medicinal chemistry, 2010, Jun-24, Volume: 53, Issue:12

    Topics: Animals; Antineoplastic Agents; Binding Sites; Drug Discovery; Drug Industry; Enzyme Inhibitors; His

2010
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
    Biogerontology, 2019, Volume: 20, Issue:4

    Topics: Aging; Drug Discovery; Humans; Ischemia; Mitochondria; NAD; Niacinamide; Nicotinamide Mononucleotide

2019
Medicinal chemistry of nicotinamide in the treatment of ischemia and reperfusion.
    Mini reviews in medicinal chemistry, 2002, Volume: 2, Issue:2

    Topics: Animals; Humans; Ischemia; MELAS Syndrome; NAD; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Poly

2002

Other Studies

16 other studies available for niacinamide and Ischemia

ArticleYear
Sirtuin 1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury.
    Critical care medicine, 2014, Volume: 42, Issue:5

    Topics: Abietanes; Analysis of Variance; Animals; Caspases; Enzyme Inhibitors; Hep G2 Cells; Humans; In Situ

2014
PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
    Nature, 2016, Mar-24, Volume: 531, Issue:7595

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Adipose Tissue; Amino Acids; Animals; Cytokines; Dinopro

2016
Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes.
    Metabolism: clinical and experimental, 2016, Volume: 65, Issue:6

    Topics: Animals; Chemokine CXCL12; Diabetes Mellitus, Type 2; Endothelial Progenitor Cells; Female; Hindlimb

2016
Comparative efficiency of succinate-containing antihypoxants in traumatic toxicosis.
    Bulletin of experimental biology and medicine, 2010, Volume: 150, Issue:2

    Topics: Animals; Antioxidants; Drug Combinations; Endotoxemia; Flavin Mononucleotide; Inosine Diphosphate; I

2010
Nicotinamide modulates energy utilization and improves functional recovery from ischemia in the in vitro rabbit retina.
    Annals of the New York Academy of Sciences, 2005, Volume: 1053

    Topics: Action Potentials; Animals; Electrophysiology; Energy Metabolism; Glucose; In Vitro Techniques; Isch

2005
Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion.
    The European respiratory journal, 2007, Volume: 30, Issue:2

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Disease Models, Animal; Free Radicals; Interl

2007
Protection from DNA damage during an ischemic cell injury.
    Biochemical and biophysical research communications, 1983, Jun-29, Volume: 113, Issue:3

    Topics: Animals; DNA; DNA Repair; Ischemia; Kidney; Male; Mice; NAD; Niacin; Niacinamide

1983
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
    Journal of medicinal chemistry, 1995, Jan-06, Volume: 38, Issue:1

    Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniqu

1995
Effects of nicorandil on the recovery of reflex potentials after spinal cord ischaemia in cats.
    British journal of pharmacology, 1995, Volume: 116, Issue:2

    Topics: Animals; Blood Pressure; Cats; Female; Ischemia; Male; Niacinamide; Nicorandil; Nitroprusside; Refle

1995
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Blood Pressure; Creatine Kin

1999
Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: Animals; DNA Damage; Drug Design; Energy Metabolism; Enzyme Inhibitors; Feedback; Humans; Ischemia;

2000
On the mode of cardioprotection produced by a new bradycardic agent, FR 76830, during ischaemia and after reperfusion in the isolated perfused rat heart: a 31P-NMR study.
    Cardiovascular research, 1990, Volume: 24, Issue:12

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Diltiazem; Dose-Respo

1990
Angiogenic potency of nucleotide metabolites: potential role in ischemia-induced vascular growth.
    Journal of molecular and cellular cardiology, 1989, Volume: 21, Issue:4

    Topics: Animals; Biological Assay; Cattle; Cell Division; Cells, Cultured; Chick Embryo; Chorion; Endotheliu

1989
Cerebral energy reserves and glycolysis in neural tissue of 6-aminonicotinamide-treated mice.
    Journal of neurobiology, 1974, Volume: 5, Issue:5

    Topics: Adenosine Triphosphate; Amines; Animals; Brain; Brain Chemistry; Cerebellum; Energy Metabolism; Fruc

1974
Behaviour of the glycolytic system of rat brain and kidney in vivo after in hibition of the glucosephosphate isomerase. II. Substrate concentrations under the influence of ischemia, 6-aminonicotinamide, and 2-deoxyglucose.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1972, Volume: 353, Issue:9

    Topics: Animals; Brain; Gluconates; Gluconeogenesis; Glucose; Glucose-6-Phosphate Isomerase; Glycolysis; Isc

1972
Inhibition of the 6-phosphogluconate dehydrogenase in the rat kidney by 6-aminonicotinamide.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:2

    Topics: Animals; Glucose-6-Phosphate Isomerase; Ischemia; Kidney; Kinetics; NADP; Niacinamide; Pentosephosph

1970