niacinamide has been researched along with Intraocular Pressure in 10 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the study two potassium channel activators, cromakalim and nicorandil, were investigated in rabbits using three different levels of intraocular pressures (IOPs), including alpha-chymotrypsin-induced ocular hypertension, hypotension (IOP recovery method) and normal tension." | 7.69 | Effects of cromakalim and nicorandil on intraocular pressure after topical administration in rabbit eyes. ( Chiang, CH; Lin, CH, 1995) |
| "In the study two potassium channel activators, cromakalim and nicorandil, were investigated in rabbits using three different levels of intraocular pressures (IOPs), including alpha-chymotrypsin-induced ocular hypertension, hypotension (IOP recovery method) and normal tension." | 3.69 | Effects of cromakalim and nicorandil on intraocular pressure after topical administration in rabbit eyes. ( Chiang, CH; Lin, CH, 1995) |
| "To analyse ophthalmological adverse events associated with mitogen-activated protein kinase kinase (MEK) inhibition with pimasertib treatment for metastatic cutaneous melanoma (CM)." | 2.87 | Pimasertib-associated ophthalmological adverse events. ( Boon, CJF; Jager, MJ; Kruit, WHJ; Luyten, GPM; van Dijk, EHC; Vingerling, JR, 2018) |
| "Of these, 42 patients with treated open-angle glaucoma and moderate visual field loss in at least 1 eye were selected for inclusion and randomized." | 1.72 | Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial. ( Blumberg, DM; Cioffi, GA; De Moraes, CG; John, SWM; Liebmann, JM; Williams, PA, 2022) |
| " The quantitative dosage also disclosed a significantly lower plasma nicotinamide concentration (-33%; P = 0." | 1.51 | Nicotinamide Deficiency in Primary Open-Angle Glaucoma. ( Allouche, S; Amati-Bonneau, P; Bocca, C; Bonneau, D; Chao de la Barca, JM; Coulbault, L; Gohier, P; Guehlouz, K; Kouassi Nzoughet, J; Lenaers, G; Leruez, S; Milea, D; Muller, J; Procaccio, V; Reynier, P; Simard, G, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 4 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Moraes, CG | 2 |
| John, SWM | 2 |
| Williams, PA | 2 |
| Blumberg, DM | 1 |
| Cioffi, GA | 2 |
| Liebmann, JM | 3 |
| Quah Qin Xian, N | 1 |
| Wong, FYK | 1 |
| Irie, J | 1 |
| Inagaki, E | 1 |
| Fujita, M | 1 |
| Nakaya, H | 1 |
| Mitsuishi, M | 1 |
| Yamaguchi, S | 1 |
| Yamashita, K | 1 |
| Shigaki, S | 1 |
| Ono, T | 1 |
| Yukioka, H | 1 |
| Okano, H | 1 |
| Nabeshima, YI | 1 |
| Imai, SI | 1 |
| Yasui, M | 1 |
| Tsubota, K | 1 |
| Itoh, H | 1 |
| Harder, JM | 1 |
| van Dijk, EHC | 1 |
| Kruit, WHJ | 1 |
| Jager, MJ | 1 |
| Luyten, GPM | 1 |
| Vingerling, JR | 1 |
| Boon, CJF | 1 |
| Kouassi Nzoughet, J | 1 |
| Chao de la Barca, JM | 1 |
| Guehlouz, K | 1 |
| Leruez, S | 1 |
| Coulbault, L | 1 |
| Allouche, S | 1 |
| Bocca, C | 1 |
| Muller, J | 1 |
| Amati-Bonneau, P | 1 |
| Gohier, P | 1 |
| Bonneau, D | 1 |
| Simard, G | 1 |
| Milea, D | 1 |
| Lenaers, G | 1 |
| Procaccio, V | 1 |
| Reynier, P | 1 |
| Chiang, CH | 1 |
| Lin, CH | 1 |
| Bouzas, EA | 1 |
| Karadimas, P | 1 |
| Mastorakos, G | 1 |
| Koutras, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study[NCT05695027] | Phase 2/Phase 3 | 188 participants (Anticipated) | Interventional | 2023-03-14 | Recruiting | ||
| Nutritional Supplements and Performance During Visual Field Testing[NCT03797469] | 32 participants (Actual) | Interventional | 2019-04-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for niacinamide and Intraocular Pressure
| Article | Year |
|---|---|
Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.
Topics: Animals; Glaucoma; Humans; Intraocular Pressure; Niacinamide; Optic Nerve Diseases; Vitamin B Comple | 2017 |
3 trials available for niacinamide and Intraocular Pressure
| Article | Year |
|---|---|
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men.
Topics: Administration, Oral; Adult; Bilirubin; Blood Glucose; Blood Pressure; Body Temperature; Chlorides; | 2020 |
Pimasertib-associated ophthalmological adverse events.
Topics: Aged; Antineoplastic Agents; Color Perception Tests; Cross-Sectional Studies; Drug-Related Side Effe | 2018 |
Antioxidant agents in the treatment of Graves' ophthalmopathy.
Topics: Administration, Oral; Adult; Allopurinol; Antioxidants; Drug Evaluation; Female; Graves Disease; Hum | 2000 |
6 other studies available for niacinamide and Intraocular Pressure
| Article | Year |
|---|---|
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma: A Phase 2 Randomized Clinical Trial.
Topics: Animals; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma-Reply.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Combined Use of Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma.
Topics: Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Niacinamide; Pyruvic Acid | 2022 |
Nicking Glaucoma with Nicotinamide?
Topics: Administration, Oral; Animals; Disease Models, Animal; Gene Expression; Genetic Therapy; Glaucoma; H | 2017 |
Nicking Glaucoma with Nicotinamide?
Topics: Administration, Oral; Animals; Disease Models, Animal; Gene Expression; Genetic Therapy; Glaucoma; H | 2017 |
Nicking Glaucoma with Nicotinamide?
Topics: Administration, Oral; Animals; Disease Models, Animal; Gene Expression; Genetic Therapy; Glaucoma; H | 2017 |
Nicking Glaucoma with Nicotinamide?
Topics: Administration, Oral; Animals; Disease Models, Animal; Gene Expression; Genetic Therapy; Glaucoma; H | 2017 |
Nicotinamide Deficiency in Primary Open-Angle Glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Chromatography, Liquid; Cohort Studies; Female | 2019 |
Effects of cromakalim and nicorandil on intraocular pressure after topical administration in rabbit eyes.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Benzopyrans; Blood Flow Velocity; Chymotr | 1995 |