niacinamide has been researched along with Innate Inflammatory Response in 110 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia." | 8.02 | Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021) |
| "Sorafenib is a standard treatment for patients (pts) with advanced hepatocellular carcinoma (aHCC), although the clinical benefit is heterogeneous between different pts groups." | 7.88 | An internally validated new clinical and inflammation-based prognostic score for patients with advanced hepatocellular carcinoma treated with sorafenib. ( Akhoundova, D; Aparicio, J; Bruixola, G; Caballero, J; Diaz-Beveridge, R; Giménez, A; Lorente, D; Rodrigo, E; Segura, Á, 2018) |
| "Response to sorafenib is highly variable in hepatocellular carcinoma (HCC)." | 7.85 | Integration of the cancer-related inflammatory response as a stratifying biomarker of survival in hepatocellular carcinoma treated with sorafenib. ( Arizumi, T; Black, J; Burlone, ME; Ferrari, C; Gibbin, A; Guaschino, G; Howell, J; Kudo, M; Pinato, DJ; Pirisi, M; Ramaswami, R; Sellers, L; Sharma, R; Toniutto, P, 2017) |
| "Quercetin could potentially be used to ameliorate myocardial damage due to oxidative stress, inflammation and apoptosis in diabetes." | 7.85 | Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin-nicotinamide-induced adult male diabetic rats. ( Giribabu, N; Karim, K; Roslan, J; Salleh, N, 2017) |
| "We evalueted a systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) with the aim to explored their prognostic value in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib." | 7.83 | Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib. ( Casadei Gardini, A; de Stefano, G; Ercolani, G; Faloppi, L; Foschi, FG; Frassineti, GL; Marisi, G; Negri, FV; Santini, D; Scarpi, E; Scartozzi, M; Silvestris, N; Valgiusti, M, 2016) |
| "In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1." | 7.78 | Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment. ( Kondo, M; Maeda, S; Morimoto, M; Morioka, Y; Moriya, S; Nozaki, A; Numata, K; Tanaka, K, 2012) |
| "These data suggest that there could be an association between sorafenib therapy and the development of cutaneous SCC and inflammation of AK." | 7.75 | Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib. ( Dubauskas, Z; Hwu, P; Jonasch, E; Kunishige, J; Prieto, VG; Tannir, NM, 2009) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 7.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| " We concluded that PD-CSNPs and PD ameliorate diabetic liver damage by modulating glucose transporter 2 expression, affecting the activity of carbohydrate metabolism enzymes, and suppressing oxidative stress and inflammation, PD-CSNPs being more efficient than PD, probably due to higher bioavailability and prolonged release." | 5.62 | Hepatoprotective Effects of Polydatin-Loaded Chitosan Nanoparticles in Diabetic Rats: Modulation of Glucose Metabolism, Oxidative Stress, and Inflammation Biomarkers. ( Abd El-Hameed, AM; Abd El-Twab, SM; Abdel-Moneim, A; El-Shahawy, AAG; Yousef, AI, 2021) |
| "Neuroinflammation is initiated by activation of the brain's innate immune system in response to an inflammatory challenge." | 5.62 | Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD ( Brenner, C; Hattori, T; Heer, CD; Higashida, H; Hori, O; Ishii, H; Nguyen, DT; O'Meally, D; Okamoto, H; Roboon, J; Takarada-Iemata, M; Yamamoto, Y, 2021) |
| "Depression is the leading cause of mental health-related disease globally, and it affects an estimated 300 million people worldwide." | 5.51 | Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone in mice. ( Fu, Z; Shen, Q; Wang, L; Xiao, Q; Xie, X; Xiong, Z; Yu, C; Zhou, J, 2019) |
| "Treatment with liraglutide-restored animals' body weight, normalized blood glucose, decreased glycated hemoglobin, and increased insulin levels." | 5.48 | Liraglutide ameliorated peripheral neuropathy in diabetic rats: Involvement of oxidative stress, inflammation and extracellular matrix remodeling. ( Abdelkader, NF; El Awdan, SA; El-Shabrawy, OA; Moustafa, PE; Zaki, HF, 2018) |
| "Sorafenib is a potent drug for advanced HCC with multikinase inhibition activity." | 5.43 | Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model. ( Axelrod, JH; Divon, MS; Galun, E; Lanton, T; Peretz, T; Salmon, A; Sonnenblick, A; Zahavi, T, 2016) |
| "0001) number of patients demonstrated improvement over their previous acne treatment regimens after both 4 and 8 weeks of NicAzel (nicotinamide, azelaic acid, zinc, pyridoxine, copper, folic acid; Elorac Inc, Vernon Hills, IL) use." | 5.16 | Inflammatory acne management with a novel prescription dietary supplement. ( Akhavan, A; Day, D; Falcon, R; Iannotta, P; Janiga, A; Kallal, JE; Olansky, A; Shalita, AR; Singri, P, 2012) |
| "This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1." | 5.15 | Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. ( Dhawan, S; Wheeland, RG, 2011) |
| " Most studies indicated that the NAD+ precursors NAM, NR, nicotinamide mononucleotide (NMN), and to a lesser extent NAD+ and NADH had a favourable outcome on several age-related disorders associated with the accumulation of chronic oxidative stress, inflammation and impaired mitochondrial function." | 5.05 | NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. ( Braidy, N; Liu, Y, 2020) |
| "The present study aimed to investigate the rationale and efficacy of using a citicoline, coenzyme Q10 (CAVAQ10) and vitamin B3 fixed combination in combating inflammation and oxidation in neuronal cells exposed to oxidative stress." | 4.12 | Citicoline/Coenzyme Q10/Vitamin B3 Fixed Combination Exerts Synergistic Protective Effects on Neuronal Cells Exposed to Oxidative Stress. ( Agnifili, L; Aloia, R; Brescia, L; Ferrante, C; Figus, M; Mastropasqua, L; Orlando, G; Rossi, GCM; Sacchi, M, 2022) |
| "Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia." | 4.02 | Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats. ( Cheng, YC; Chiu, YM; Dai, ZK; Wu, BN, 2021) |
| "The current work aimed to examine the properties of oral supplementation of niacinamide and undenatured type II collagen (UCII) on the inflammation and joint pain behavior of rats with osteoarthritis (OA)." | 4.02 | Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis. ( Durmus, AS; Juturu, V; Kucuk, O; Orhan, C; Ozercan, IH; Sahin, K; Sahin, N; Tuzcu, M, 2021) |
| "Sorafenib is a standard treatment for patients (pts) with advanced hepatocellular carcinoma (aHCC), although the clinical benefit is heterogeneous between different pts groups." | 3.88 | An internally validated new clinical and inflammation-based prognostic score for patients with advanced hepatocellular carcinoma treated with sorafenib. ( Akhoundova, D; Aparicio, J; Bruixola, G; Caballero, J; Diaz-Beveridge, R; Giménez, A; Lorente, D; Rodrigo, E; Segura, Á, 2018) |
| "Quercetin could potentially be used to ameliorate myocardial damage due to oxidative stress, inflammation and apoptosis in diabetes." | 3.85 | Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin-nicotinamide-induced adult male diabetic rats. ( Giribabu, N; Karim, K; Roslan, J; Salleh, N, 2017) |
| "Response to sorafenib is highly variable in hepatocellular carcinoma (HCC)." | 3.85 | Integration of the cancer-related inflammatory response as a stratifying biomarker of survival in hepatocellular carcinoma treated with sorafenib. ( Arizumi, T; Black, J; Burlone, ME; Ferrari, C; Gibbin, A; Guaschino, G; Howell, J; Kudo, M; Pinato, DJ; Pirisi, M; Ramaswami, R; Sellers, L; Sharma, R; Toniutto, P, 2017) |
| "We evalueted a systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) with the aim to explored their prognostic value in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib." | 3.83 | Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib. ( Casadei Gardini, A; de Stefano, G; Ercolani, G; Faloppi, L; Foschi, FG; Frassineti, GL; Marisi, G; Negri, FV; Santini, D; Scarpi, E; Scartozzi, M; Silvestris, N; Valgiusti, M, 2016) |
| "In 81 patients receiving sorafenib treatment for advanced HCC, we evaluated the prognostic significance of an inflammation-based prognostic score, the Glasgow prognostic score [evidenced by an elevated C-reactive protein level (>1." | 3.78 | Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment. ( Kondo, M; Maeda, S; Morimoto, M; Morioka, Y; Moriya, S; Nozaki, A; Numata, K; Tanaka, K, 2012) |
| "These data suggest that there could be an association between sorafenib therapy and the development of cutaneous SCC and inflammation of AK." | 3.75 | Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib. ( Dubauskas, Z; Hwu, P; Jonasch, E; Kunishige, J; Prieto, VG; Tannir, NM, 2009) |
| "Pellagra is a curable dietary illness that unchecked leads to dementia, diarrhoea, dermatitis and death due to lack of the precursors for NAD(H)." | 3.74 | Pellagra: A clue as to why energy failure causes diseases? ( Ramsden, DB; Williams, AC, 2007) |
| " Here we investigated the effect of nicaraven (2(R,S)-1,2-bis(nicotinamido)propane), a known hydroxyl radical scavenger compound and neuroprotective agent, on several NO- and peroxynitrite related pathways in vitro, and in shock and inflammation in vivo." | 3.70 | Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation. ( Hake, P; Salzman, AL; Scott, GS; Szabo, C; Zingarelli, B, 2000) |
| " administration of D-galactosamine, and it rather showed a decrease together with necrosis after carbon tetrachloride administration." | 3.68 | N1-methylnicotinamide level in the blood after nicotinamide loading as further evidence for malignant tumor burden. ( Fujimura, S; Kato, N; Miyazaki, M; Moriyama, Y; Nakagawa, K; Okui, K, 1991) |
| "The hexose monophosphate shunt inhibitor 6-aminonicotinamide was observed to have an anti-inflammatory effect in the treatment of experimental uveitis." | 3.68 | Pharmacologic modulation of acute uveitis with aminonicotinamide. ( Donoso, LA; Gregerson, D; Marak, GE; Rao, NA; Sery, TW, 1990) |
| " Cohort B involved a modified schedule of sorafenib dosing on days 1-5 of each 14-day pemetrexed cycle." | 2.82 | Phase I study of pemetrexed with sorafenib in advanced solid tumors. ( Booth, L; Bose, P; Dent, P; Geyer, CE; Gordon, S; Kmieciak, M; Massey, HD; McGuire, WP; Moran, RG; Poklepovic, A; Quigley, M; Roberts, JD; Shafer, DA; Shrader, E; Strickler, K; Tombes, MB; Wan, W, 2016) |
| "Bone biopsy confirmed metastases of prostate cancer." | 1.62 | False-Positive 18F-Prostate-Specific Membrane Antigen-1007 PET/CT Caused by Hepatic Multifocal Inflammatory Foci. ( Canelo, A; Ladrón-de-Guevara, D; Piottante, A; Regonesi, C, 2021) |
| " We concluded that PD-CSNPs and PD ameliorate diabetic liver damage by modulating glucose transporter 2 expression, affecting the activity of carbohydrate metabolism enzymes, and suppressing oxidative stress and inflammation, PD-CSNPs being more efficient than PD, probably due to higher bioavailability and prolonged release." | 1.62 | Hepatoprotective Effects of Polydatin-Loaded Chitosan Nanoparticles in Diabetic Rats: Modulation of Glucose Metabolism, Oxidative Stress, and Inflammation Biomarkers. ( Abd El-Hameed, AM; Abd El-Twab, SM; Abdel-Moneim, A; El-Shahawy, AAG; Yousef, AI, 2021) |
| "Neuroinflammation is initiated by activation of the brain's innate immune system in response to an inflammatory challenge." | 1.62 | Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD ( Brenner, C; Hattori, T; Heer, CD; Higashida, H; Hori, O; Ishii, H; Nguyen, DT; O'Meally, D; Okamoto, H; Roboon, J; Takarada-Iemata, M; Yamamoto, Y, 2021) |
| "Chronic alcohol abuse is common and a leading cause of alcoholic liver disease (ALD)." | 1.56 | Adult zebrafish as an in vivo drug testing model for ethanol induced acute hepatic injury. ( Kim, SH; Park, KH, 2020) |
| "Postoperative SIR-induced tumor metastasis have been clearly evidenced in our experimental model, and the administration of nicaraven may ameliorate the SIR-induced tumor metastasis by suppressing inflammatory responses." | 1.56 | Nicaraven Attenuates Postoperative Systemic Inflammatory Responses-Induced Tumor Metastasis. ( Goto, S; Guo, CY; Kawabata, T; Li, TS; Liu, KX; Moriwaki, T; Zhang, X, 2020) |
| "Depression is the leading cause of mental health-related disease globally, and it affects an estimated 300 million people worldwide." | 1.51 | Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone in mice. ( Fu, Z; Shen, Q; Wang, L; Xiao, Q; Xie, X; Xiong, Z; Yu, C; Zhou, J, 2019) |
| "Renal interstitial fibrosis is a common pathological feature in progressive kidney diseases currently lacking effective treatment." | 1.51 | Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation. ( Cai, J; Dong, Z; Liu, Z; Shu, S; Tang, C; Wang, Y; Zheng, M, 2019) |
| "Treatment with liraglutide-restored animals' body weight, normalized blood glucose, decreased glycated hemoglobin, and increased insulin levels." | 1.48 | Liraglutide ameliorated peripheral neuropathy in diabetic rats: Involvement of oxidative stress, inflammation and extracellular matrix remodeling. ( Abdelkader, NF; El Awdan, SA; El-Shabrawy, OA; Moustafa, PE; Zaki, HF, 2018) |
| "Trehalose treatment reduced the activation of the UPR and inflammatory signaling, and reduced liver injury." | 1.46 | Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice. ( Estrada, AL; Hudson, WM; LaRocca, TJ; Pagliassotti, MJ; Seals, DR; Wang, D; Wei, Y; Zigler, ML, 2017) |
| "Sorafenib is a potent drug for advanced HCC with multikinase inhibition activity." | 1.43 | Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model. ( Axelrod, JH; Divon, MS; Galun, E; Lanton, T; Peretz, T; Salmon, A; Sonnenblick, A; Zahavi, T, 2016) |
| "augusta leaves (AA) against type 2 diabetes mellitus (T2DM) and its associated nephropathy and cardiomyopathy in experimental rats." | 1.42 | Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response. ( De Feo, V; Dewanjee, S; Gangopadhyay, M; K Dua, T; Khanra, R; Sahu, R; Zia-Ul-Haq, M, 2015) |
| "Inflammation is closely associated with pathogenesis of various metabolic disorders, cardiovascular diseases, and cancers." | 1.39 | Combined NMR and GC-MS analyses revealed dynamic metabolic changes associated with the carrageenan-induced rat pleurisy. ( An, Y; Lei, H; Li, H; Tang, H; Wang, Y; Zhang, L, 2013) |
| "Sorafenib was acutely administered to NASH rats with IR liver injury that were or were not chronically pretreated with the Rho-kinase-specific inhibitor fasudil." | 1.38 | Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis. ( Chan, CC; Huang, YT; Lee, KC; Lee, TY; Lin, HC; Yang, YY; Yeh, YC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (4.55) | 18.7374 |
| 1990's | 7 (6.36) | 18.2507 |
| 2000's | 15 (13.64) | 29.6817 |
| 2010's | 56 (50.91) | 24.3611 |
| 2020's | 27 (24.55) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Cheng, YC | 1 |
| Chiu, YM | 1 |
| Dai, ZK | 1 |
| Wu, BN | 1 |
| Camillo, L | 1 |
| Gironi, LC | 1 |
| Zavattaro, E | 1 |
| Esposto, E | 1 |
| Savoia, P | 1 |
| Abdelghany, L | 1 |
| Zhang, X | 2 |
| Kawabata, T | 2 |
| Goto, S | 2 |
| El-Mahdy, N | 1 |
| Jingu, K | 1 |
| Li, TS | 2 |
| Mastropasqua, L | 1 |
| Agnifili, L | 1 |
| Ferrante, C | 1 |
| Sacchi, M | 1 |
| Figus, M | 1 |
| Rossi, GCM | 1 |
| Brescia, L | 1 |
| Aloia, R | 1 |
| Orlando, G | 1 |
| Niu, LG | 1 |
| Sun, N | 1 |
| Liu, KL | 1 |
| Su, Q | 1 |
| Qi, J | 1 |
| Fu, LY | 1 |
| Xin, GR | 1 |
| Kang, YM | 1 |
| Baweja, S | 1 |
| Kumari, A | 1 |
| Negi, P | 1 |
| Tomar, A | 1 |
| Tripathi, DM | 1 |
| Mourya, AK | 1 |
| Rastogi, A | 1 |
| Subudhi, PD | 1 |
| Thangariyal, S | 1 |
| Kumar, G | 1 |
| Kumar, J | 1 |
| Reddy, GS | 1 |
| Sood, AK | 1 |
| Vashistha, C | 1 |
| Sarohi, V | 1 |
| Bihari, C | 1 |
| Maiwall, R | 1 |
| Sarin, SK | 1 |
| Noei Razliqi, R | 1 |
| Ahangarpour, A | 2 |
| Mard, SA | 2 |
| Khorsandi, L | 2 |
| Razliqi, RN | 1 |
| Curran, CS | 1 |
| Dougherty, EJ | 1 |
| Cui, X | 1 |
| Li, Y | 1 |
| Jeakle, M | 1 |
| Gamble, T | 1 |
| Demirkale, CY | 1 |
| Torabi-Parizi, P | 1 |
| Niño-Narvión, J | 1 |
| Rojo-López, MI | 1 |
| Martinez-Santos, P | 1 |
| Rossell, J | 1 |
| Ruiz-Alcaraz, AJ | 1 |
| Alonso, N | 1 |
| Ramos-Molina, B | 1 |
| Mauricio, D | 1 |
| Julve, J | 1 |
| Ramírez-Cruz, A | 1 |
| Gómez-González, B | 1 |
| Baiza-Gutman, LA | 2 |
| Manuel-Apolinar, L | 2 |
| Ángeles-Mejía, S | 2 |
| López-Cervantes, SP | 1 |
| Ortega-Camarillo, C | 1 |
| Cruz-López, M | 2 |
| Gómez-Olivares, JL | 2 |
| Díaz-Flores, M | 2 |
| Song, SB | 1 |
| Park, JS | 1 |
| Chung, GJ | 1 |
| Lee, IH | 1 |
| Hwang, ES | 1 |
| Xiao, Q | 1 |
| Xiong, Z | 1 |
| Yu, C | 1 |
| Zhou, J | 1 |
| Shen, Q | 1 |
| Wang, L | 1 |
| Xie, X | 1 |
| Fu, Z | 1 |
| Shi, W | 1 |
| Hegeman, MA | 1 |
| Doncheva, A | 1 |
| Bekkenkamp-Grovenstein, M | 1 |
| de Boer, VCJ | 1 |
| Keijer, J | 1 |
| Moriwaki, T | 1 |
| Liu, KX | 1 |
| Guo, CY | 1 |
| Braidy, N | 1 |
| Liu, Y | 2 |
| Villeda-González, JD | 1 |
| Damasio-Santana, L | 1 |
| Millán-Pacheco, C | 1 |
| Cortés-Ginez, MC | 1 |
| Vidal-Moreno, CJ | 1 |
| Fragola, G | 1 |
| Mabb, AM | 1 |
| Taylor-Blake, B | 1 |
| Niehaus, JK | 1 |
| Chronister, WD | 1 |
| Mao, H | 1 |
| Simon, JM | 1 |
| Yuan, H | 1 |
| Li, Z | 1 |
| McConnell, MJ | 1 |
| Zylka, MJ | 1 |
| Bierman, JC | 1 |
| Laughlin, T | 1 |
| Tamura, M | 1 |
| Hulette, BC | 1 |
| Mack, CE | 1 |
| Sherrill, JD | 1 |
| Tan, CYR | 1 |
| Morenc, M | 1 |
| Bellanger, S | 1 |
| Oblong, JE | 1 |
| Zhou, B | 1 |
| Wang, DD | 1 |
| Qiu, Y | 1 |
| Airhart, S | 1 |
| Stempien-Otero, A | 1 |
| O'Brien, KD | 1 |
| Tian, R | 1 |
| Park, KH | 1 |
| Kim, SH | 1 |
| Wang, ZK | 1 |
| Chen, RR | 1 |
| Li, JH | 1 |
| Chen, JY | 1 |
| Li, W | 1 |
| Niu, XL | 1 |
| Wang, FF | 1 |
| Wang, J | 1 |
| Yang, JX | 1 |
| Ladrón-de-Guevara, D | 1 |
| Canelo, A | 1 |
| Piottante, A | 1 |
| Regonesi, C | 1 |
| Li, J | 1 |
| Jia, Z | 1 |
| Zhang, Q | 1 |
| Dai, J | 1 |
| Kong, J | 1 |
| Fan, Z | 1 |
| Li, G | 1 |
| Abd El-Hameed, AM | 1 |
| Yousef, AI | 1 |
| Abd El-Twab, SM | 1 |
| El-Shahawy, AAG | 1 |
| Abdel-Moneim, A | 1 |
| Kang, H | 1 |
| Park, YK | 1 |
| Lee, JY | 1 |
| Roboon, J | 1 |
| Hattori, T | 1 |
| Ishii, H | 1 |
| Takarada-Iemata, M | 1 |
| Nguyen, DT | 1 |
| Heer, CD | 1 |
| O'Meally, D | 1 |
| Brenner, C | 2 |
| Yamamoto, Y | 1 |
| Okamoto, H | 1 |
| Higashida, H | 1 |
| Hori, O | 1 |
| O'Brien, A | 1 |
| Hanlon, MM | 1 |
| Marzaioli, V | 1 |
| Wade, SC | 1 |
| Flynn, K | 1 |
| Fearon, U | 1 |
| Veale, DJ | 1 |
| Sahin, K | 1 |
| Kucuk, O | 1 |
| Orhan, C | 1 |
| Tuzcu, M | 1 |
| Durmus, AS | 1 |
| Ozercan, IH | 1 |
| Sahin, N | 1 |
| Juturu, V | 1 |
| Lopez-Sanz, L | 1 |
| Bernal, S | 1 |
| Jimenez-Castilla, L | 1 |
| Prieto, I | 1 |
| La Manna, S | 1 |
| Gomez-Lopez, S | 1 |
| Blanco-Colio, LM | 1 |
| Egido, J | 1 |
| Martin-Ventura, JL | 1 |
| Gomez-Guerrero, C | 1 |
| Bathina, S | 1 |
| Srinivas, N | 1 |
| Das, UN | 1 |
| Pagliassotti, MJ | 1 |
| Estrada, AL | 1 |
| Hudson, WM | 1 |
| Wei, Y | 1 |
| Wang, D | 1 |
| Seals, DR | 1 |
| Zigler, ML | 1 |
| LaRocca, TJ | 1 |
| Martens, S | 1 |
| Jeong, M | 1 |
| Tonnus, W | 1 |
| Feldmann, F | 1 |
| Hofmans, S | 1 |
| Goossens, V | 1 |
| Takahashi, N | 1 |
| Bräsen, JH | 1 |
| Lee, EW | 1 |
| Van der Veken, P | 1 |
| Joossens, J | 1 |
| Augustyns, K | 1 |
| Fulda, S | 1 |
| Linkermann, A | 1 |
| Song, J | 1 |
| Vandenabeele, P | 1 |
| Giribabu, N | 4 |
| Karim, K | 2 |
| Kilari, EK | 1 |
| Kassim, NM | 1 |
| Salleh, N | 4 |
| Li, XF | 1 |
| Chen, C | 1 |
| Xiang, DM | 1 |
| Qu, L | 1 |
| Sun, W | 1 |
| Lu, XY | 1 |
| Zhou, TF | 1 |
| Chen, SZ | 1 |
| Ning, BF | 1 |
| Cheng, Z | 1 |
| Xia, MY | 1 |
| Shen, WF | 1 |
| Yang, W | 1 |
| Wen, W | 1 |
| Lee, TKW | 1 |
| Cong, WM | 1 |
| Wang, HY | 1 |
| Ding, J | 1 |
| Nakatsu, Y | 1 |
| Kokubo, H | 1 |
| Bumdelger, B | 1 |
| Yoshizumi, M | 1 |
| Yamamotoya, T | 1 |
| Matsunaga, Y | 1 |
| Ueda, K | 1 |
| Inoue, Y | 1 |
| Inoue, MK | 1 |
| Fujishiro, M | 1 |
| Kushiyama, A | 1 |
| Ono, H | 1 |
| Sakoda, H | 1 |
| Asano, T | 1 |
| Diaz-Beveridge, R | 1 |
| Bruixola, G | 1 |
| Lorente, D | 1 |
| Caballero, J | 1 |
| Rodrigo, E | 1 |
| Segura, Á | 1 |
| Akhoundova, D | 1 |
| Giménez, A | 1 |
| Aparicio, J | 1 |
| Hsu, JD | 1 |
| Wu, CC | 1 |
| Hung, CN | 1 |
| Wang, CJ | 1 |
| Huang, HP | 1 |
| Adam, SH | 1 |
| Bakar, NMA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Preoperative Nicotinamide Riboside (Vitamin B3) Supplementation in Patients Undergoing Elective Left Ventricular Assist Device (LVAD) Implantation[NCT03727646] | Early Phase 1 | 5 participants (Actual) | Interventional | 2018-09-26 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for niacinamide and Innate Inflammatory Response
| Article | Year |
|---|---|
NAD+ Precursors and Intestinal Inflammation: Therapeutic Insights Involving Gut Microbiota.
Topics: Animals; Dysbiosis; Gastrointestinal Microbiome; Humans; Inflammation; Mammals; NAD; Niacinamide | 2023 |
Diverse therapeutic efficacies and more diverse mechanisms of nicotinamide.
Topics: Animals; Cell Survival; Fibrosis; Humans; Inflammation; Mitochondria; Neoplasms; Niacinamide; Skin D | 2019 |
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis.
Topics: Aging; Animals; Humans; Inflammation; Mice; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinami | 2020 |
Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Chemoprevention; Dermatology; DNA Damage; | 2019 |
Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience.
Topics: Animals; Enzyme Inhibitors; Humans; Inflammation; Neoplasms; Niacinamide; Nicotinamide Phosphoribosy | 2013 |
Telomerase inhibitors: a patent review (2010-2015).
Topics: Animals; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Indoles; Inflammation; Neopl | 2016 |
NAMPT in regulated NAD biosynthesis and its pivotal role in human metabolism.
Topics: Animals; Humans; Inflammation; Insulin; Insulin Secretion; Longevity; NAD; Niacinamide; Nicotinamide | 2011 |
Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzenesulfonates; Chemotaxis; C | 2012 |
Navigating novel mechanisms of cellular plasticity with the NAD+ precursor and nutrient nicotinamide.
Topics: Aging; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspases; Cell Survival; Endothel | 2004 |
Essential contribution of macrophages to islet cell destruction in vivo and in vitro.
Topics: Animals; Antigens, Surface; Cytotoxicity, Immunologic; Inflammation; Islets of Langerhans; Macrophag | 1990 |
5 trials available for niacinamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure.
Topics: Female; Heart Failure; Humans; Inflammation; Leukocytes, Mononuclear; Male; Mitochondria, Heart; Mod | 2020 |
Phase I study of pemetrexed with sorafenib in advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumo | 2016 |
Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system.
Topics: Acne Vulgaris; Adult; Combined Modality Therapy; Dermatologic Agents; Dicarboxylic Acids; Drug Combi | 2011 |
Influence of niacinamide containing formulations on the molecular and biophysical properties of the stratum corneum.
Topics: Administration, Cutaneous; Adult; Female; Fibrinolysin; Humans; Inflammation; Kallikreins; Male; Nia | 2013 |
Inflammatory acne management with a novel prescription dietary supplement.
Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Copper; Dicarboxylic Acids; Dietary | 2012 |
95 other studies available for niacinamide and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats.
Topics: Animals; Antioxidants; Behavior, Animal; Blood Glucose; Body Weight; Calcitonin Gene-Related Peptide | 2021 |
Nicotinamide Attenuates UV-Induced Stress Damage in Human Primary Keratinocytes from Cancerization Fields.
Topics: DNA Damage; Humans; Inflammation; Keratinocytes; Niacinamide; Nitric Oxide; Reactive Oxygen Species; | 2022 |
Nicaraven prevents the fast growth of inflamed tumors by an anti-inflammatory mechanism.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers, Tumor; Cytokines; Humans; Inflammation; Macrophages; | 2021 |
Citicoline/Coenzyme Q10/Vitamin B3 Fixed Combination Exerts Synergistic Protective Effects on Neuronal Cells Exposed to Oxidative Stress.
Topics: Brain-Derived Neurotrophic Factor; Cytidine Diphosphate Choline; Dopamine; Humans; Inflammation; Int | 2022 |
Genistein Alleviates Oxidative Stress and Inflammation in the Hypothalamic Paraventricular Nucleus by Activating the Sirt1/Nrf2 Pathway in High Salt-Induced Hypertension.
Topics: Animals; Antioxidants; Cardiomegaly; Cytokines; Genistein; Glutathione Disulfide; Hypertension; Infl | 2022 |
Hepatopulmonary syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod.
Topics: Animals; Fingolimod Hydrochloride; Hepatopulmonary Syndrome; Inflammation; Liver Cirrhosis; Mice; Ni | 2023 |
Gentisic acid protects against diabetic nephropathy in Nicotinamide-Streptozotocin administered male mice by attenuating oxidative stress and inflammation: The role of miR-200a/Keap1/Nrf2 pathway, renin-angiotensin system (RAS) and NF-кB.
Topics: Angiotensins; Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes Mellitus, Experimental; Diab | 2023 |
Gentisic acid ameliorates type 2 diabetes induced by Nicotinamide-Streptozotocin in male mice by attenuating pancreatic oxidative stress and inflammation through modulation of Nrf2 and NF-кB pathways.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Kel | 2023 |
Nicotinamide Antagonizes Lipopolysaccharide-Induced Hypoxic Cell Signals in Human Macrophages.
Topics: Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lipopolysaccharides; Macro | 2023 |
Nicotinamide, an acetylcholinesterase uncompetitive inhibitor, protects the blood‒brain barrier and improves cognitive function in rats fed a hypercaloric diet.
Topics: Acetylcholinesterase; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinester | 2023 |
Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Carotenoids; Corticosterone; Depression; Hippocamp | 2019 |
High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet.
Topics: Adipose Tissue, White; Animals; Blood Glucose; Diet, High-Fat; Dose-Response Relationship, Drug; Ene | 2019 |
Nicaraven Attenuates Postoperative Systemic Inflammatory Responses-Induced Tumor Metastasis.
Topics: Animals; Cytokines; Inflammation; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Met | 2020 |
Nicotinamide reduces inflammation and oxidative stress via the cholinergic system in fructose-induced metabolic syndrome in rats.
Topics: Acetylcholinesterase; Animals; Anthropometry; Anti-Inflammatory Agents; Aryldialkylphosphatase; Buty | 2020 |
Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration.
Topics: Animals; Apoptosis; Cerebral Cortex; DNA Damage; DNA Topoisomerases, Type I; Genomic Instability; Hi | 2020 |
Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin.
Topics: Biomarkers; Cellular Senescence; Double-Blind Method; Epidermis; Female; Humans; Inflammation; Kerat | 2020 |
Adult zebrafish as an in vivo drug testing model for ethanol induced acute hepatic injury.
Topics: Alanine Transaminase; Alcoholism; Animals; Disease Models, Animal; Ethanol; Gene Expression Regulati | 2020 |
Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway.
Topics: Animals; Cardiotonic Agents; Enzyme Inhibitors; Heart; Inflammasomes; Inflammation; Isoflavones; Mal | 2020 |
False-Positive 18F-Prostate-Specific Membrane Antigen-1007 PET/CT Caused by Hepatic Multifocal Inflammatory Foci.
Topics: Aged; Biopsy; Bone Neoplasms; False Positive Reactions; Fluorine Radioisotopes; Humans; Inflammation | 2021 |
Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats.
Topics: Animals; Aquaporin 4; Astrocytes; Cell Proliferation; Disease Models, Animal; Female; Flavonoids; In | 2021 |
Hepatoprotective Effects of Polydatin-Loaded Chitosan Nanoparticles in Diabetic Rats: Modulation of Glucose Metabolism, Oxidative Stress, and Inflammation Biomarkers.
Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Glucose; Glucosides; Inflammation; Lipid Peroxid | 2021 |
Nicotinamide riboside, an NAD
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ethanol; Inflammation; Macrophages; Mice; Niacinami | 2021 |
Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD
Topics: ADP-ribosyl Cyclase 1; Animals; Apigenin; Astrocytes; Chemokines; Cytokines; Gene Deletion; Hippocam | 2021 |
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function.
Topics: Adamantane; Adult; Aged; Arthritis, Psoriatic; Azetidines; Cells, Cultured; Female; Fibroblasts; Het | 2021 |
Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis.
Topics: Animals; Collagen Type II; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inflam | 2021 |
Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.
Topics: Animals; Antigen-Antibody Complex; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Ani | 2021 |
Streptozotocin produces oxidative stress, inflammation and decreases BDNF concentrations to induce apoptosis of RIN5F cells and type 2 diabetes mellitus in Wistar rats.
Topics: Animals; Apoptosis; Blood Glucose; Brain-Derived Neurotrophic Factor; Cell Line; Cell Survival; Diab | 2017 |
Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice.
Topics: Aging; AMP-Activated Protein Kinase Kinases; Animals; Autophagy; Biomarkers; Blood Glucose; Dietary | 2017 |
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.
Topics: Animals; Apoptosis; Cell Death; Disease Models, Animal; Humans; Inflammation; Mice; Necrosis; Niacin | 2017 |
Anti-Inflammatory, Antiapoptotic and Proproliferative Effects of Vitis vinifera Seed Ethanolic Extract in the Liver of Streptozotocin-Nicotinamide-Induced Type 2 Diabetes in Male Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cell Proliferation; Diabetes Mellitus, E | 2018 |
Chronic inflammation-elicited liver progenitor cell conversion to liver cancer stem cell with clinical significance.
Topics: Animals; Antigens, Differentiation; Antineoplastic Agents; Cell Self Renewal; Cell Transformation, N | 2017 |
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Adhesion Molecules; Cytokines; Diabetes Mel | 2017 |
An internally validated new clinical and inflammation-based prognostic score for patients with advanced hepatocellular carcinoma treated with sorafenib.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Carcinoma, Hepatocellular; | 2018 |
Myrciaria cauliflora extract improves diabetic nephropathy via suppression of oxidative stress and inflammation in streptozotocin-nicotinamide mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Mice; Myrtaceae; Nia | 2016 |
Marantodes pumilum (Kacip fatimah) enhances in-vitro glucose uptake in 3T3-L1 adipocyte cells and reduces pancreatic complications in streptozotocin-nicotinamide induced male diabetic rats.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Antioxidants; Biological Transport; Blood Glucose; Diabetes Melli | 2017 |
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
Topics: Animals; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Healthy Aging; In | 2018 |
Liraglutide ameliorated peripheral neuropathy in diabetic rats: Involvement of oxidative stress, inflammation and extracellular matrix remodeling.
Topics: Animals; Antibiotics, Antineoplastic; Blood Glucose; Body Weight; Diabetic Neuropathies; Disease Mod | 2018 |
Restorative potentiality of S-allylcysteine against diabetic nephropathy through attenuation of oxidative stress and inflammation in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cysteine; Diabetes Mellitus, Experimental; Diabetic Ne | 2019 |
NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Gene Expression Regul | 2019 |
Effects of nicotinamide on spatial memory and inflammation after juvenile traumatic brain injury.
Topics: Age Factors; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Inflammation; Male; Maze Learning; | 2019 |
Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation.
Topics: Animals; Apoptosis; Cell Line; Chemokine CCL2; Disease Models, Animal; Fibrosis; Inflammation; Inter | 2019 |
Resveratrol inhibits ionising irradiation-induced inflammation in MSCs by activating SIRT1 and limiting NLRP-3 inflammasome activation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Cells, Cultured; Humans; Inflammation; In | 2013 |
The protective effect of fenofibrate against TNF-α-induced CD40 expression through SIRT1-mediated deacetylation of NF-κB in endothelial cells.
Topics: Acetylation; Antioxidants; Benzamides; CD40 Antigens; Cells, Cultured; Fenofibrate; Human Umbilical | 2014 |
Combined NMR and GC-MS analyses revealed dynamic metabolic changes associated with the carrageenan-induced rat pleurisy.
Topics: Acute-Phase Proteins; Animals; Carrageenan; Choline; Citric Acid Cycle; Fatty Acids; Gas Chromatogra | 2013 |
Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Boronic Acids; Chemokine CXC | 2014 |
G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Humans; I | 2014 |
Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response.
Topics: Adenosine Triphosphate; Animals; Biomarkers; Blood Glucose; Body Weight; Cardiomyopathies; Diabetes | 2015 |
Perinatal asphyxia leads to PARP-1 overactivity, p65 translocation, IL-1β and TNF-α overexpression, and apoptotic-like cell death in mesencephalon of neonatal rats: prevention by systemic neonatal nicotinamide administration.
Topics: Animals; Animals, Newborn; Apoptosis; Asphyxia; Asphyxia Neonatorum; Humans; Inflammation; Interleuk | 2015 |
Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding model.
Topics: Animals; Boronic Acids; Computational Biology; Drug Design; Inflammation; Lung Diseases; Molecular S | 2015 |
Nicotinamide Riboside Ameliorates Hepatic Metaflammation by Modulating NLRP3 Inflammasome in a Rodent Model of Type 2 Diabetes.
Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Blood Glucose; CARD S | 2015 |
The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.
Topics: Acquired Immunodeficiency Syndrome; Adult; Africa South of the Sahara; Antiretroviral Therapy, Highl | 2015 |
Ethyl acetate fraction of Cissus quadrangularis stem ameliorates hyperglycaemia-mediated oxidative stress and suppresses inflammatory response in nicotinamide/streptozotocin induced type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cissus; Cytokines; Diabetes Mellitus, Experimental; Glycated H | 2015 |
The Effects of Probiotic Soymilk Fortified with Omega-3 on Blood Glucose, Lipid Profile, Haematological and Oxidative Stress, and Inflammatory Parameters in Streptozotocin Nicotinamide-Induced Diabetic Rats.
Topics: Animals; Blood Glucose; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimenta | 2015 |
Nicotinamide: a vitamin able to shift macrophage differentiation toward macrophages with restricted inflammatory features.
Topics: Cell Differentiation; Cells, Cultured; Eicosanoids; Gene Expression Regulation; Granulocyte-Macropha | 2015 |
Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP-Bindin | 2016 |
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Obesity Agents; Cells, Cultured; Diet, High-Fat; | 2016 |
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.
Topics: Administration, Oral; Aging; Animals; Biological Availability; Energy Metabolism; Glucose; Homeostas | 2016 |
Methanolic seed extract of Vitis vinifera ameliorates oxidative stress, inflammation and ATPase dysfunction in infarcted and non-infarcted heart of streptozotocin-nicotinamide induced male diabetic rats.
Topics: Adenosine Triphosphatases; Animals; Diabetes Mellitus, Experimental; Grape Seed Extract; Inflammatio | 2016 |
Immune inflammation indicators and implication for immune modulation strategies in advanced hepatocellular carcinoma patients receiving sorafenib.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Hepatocellular; Disease-Free Survi | 2016 |
Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin-nicotinamide-induced adult male diabetic rats.
Topics: Animals; Apoptosis; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Heart; Heart Rat | 2017 |
Integration of the cancer-related inflammatory response as a stratifying biomarker of survival in hepatocellular carcinoma treated with sorafenib.
Topics: Aged; Antineoplastic Agents; Biomarkers; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Human | 2017 |
Systemic and immunotoxicity of pristine and PEGylated multi-walled carbon nanotubes in an intravenous 28 days repeated dose toxicity study.
Topics: Animals; Biphenyl Compounds; Body Weight; Carbamates; Cells, Cultured; Erythrocytes; Female; Immunoe | 2017 |
Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.
Topics: Administration, Oral; Animals; Benzothiazoles; Capsaicin; Cell Line; Chemistry, Pharmaceutical; Drug | 2008 |
An increased regional blood flow precedes mesenteric inflammation in rats treated by a phosphodiesterase 4 inhibitor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; A | 2009 |
Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib.
Topics: Aged; Benzenesulfonates; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Drug Eruptions; Female; Hu | 2009 |
Relationship between phosphodiesterase type 4 inhibition and anti-inflammatory activity of CI-1044 in rat airways.
Topics: Administration, Oral; Animals; Azepines; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Mode | 2010 |
Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.
Topics: Adult; Aged; Apoptosis; Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Female; Flow Cyto | 2010 |
1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats.
Topics: Animals; Biomarkers; Diabetes Mellitus; Endothelium, Vascular; Hemostasis; Hypolipidemic Agents; Inf | 2010 |
Effects of dietary glutamine on inflammatory mediator gene expressions in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Chemokine CCL2; Diabetes Mellitus, Experimental; Dietary Supplements; Diseas | 2012 |
Inflammation-based prognostic score for hepatocellular carcinoma patients on sorafenib treatment.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; | 2012 |
Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis.
Topics: Animals; Apoptosis; Disease Models, Animal; Fatty Liver; Gene Expression Regulation, Enzymologic; He | 2012 |
Negative transcriptional regulation of inflammatory genes by group B3 vitamin nicotinamide.
Topics: Animals; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; Niacinamide; Poly | 2012 |
Nicotinamide increases systemic vascular resistance in ovine endotoxemia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Disease Mode | 2003 |
The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents.
Topics: Administration, Oral; Animals; Bronchoconstriction; Edema; Enzyme Inhibitors; Humans; In Vitro Techn | 2003 |
[Metabolism of nicotinamide in man. II. Venous tolerance test in inflammatory processes].
Topics: Inflammation; Multiple Endocrine Neoplasia Type 2a; Niacin; Niacinamide; Veins | 1952 |
[Comparative studies on the antiphlogistic effect of nicotinoamide-phenyl-dimethylpyrazolone and its combination with prednisone].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Humans; Inflammation; Niacin; Niacin | 1963 |
Nicotinamide inhibits endotoxin-induced monocyte tissue factor expression.
Topics: Adult; Blood Coagulation; Blood Coagulation Tests; CD11b Antigen; Drug Antagonism; Endotoxins; Human | 2003 |
Neuroprotective effects of nicotinamide after experimental spinal cord injury.
Topics: Acute Disease; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Inflammation; Inject | 2004 |
Altered gene expression in rat mesenteric tissue following in vivo exposure to a phosphodiesterase 4 inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Azepines; Cluster Analysis; Cyclic Nucleotide Phosphod | 2007 |
Pellagra: A clue as to why energy failure causes diseases?
Topics: Animals; Biochemistry; Diet; Humans; Infections; Inflammation; Metabolism; Models, Biological; Model | 2007 |
Interstitial nephritis in a patient taking sorafenib.
Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Biopsy; Carcinoma, Renal Cell; Disease-Free Survival | 2007 |
Synthesis and evaluation of the antiinflammatory activity of N-[2-(3,5-di-tert-butyl-4-hydroxyphenyl)-4-oxo-thiazolidin-3-yl]-nicotinamide.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Exp | 2007 |
In vivo bioactivity and biodistribution of chemotactic peptide analogs in nonhuman primates.
Topics: Animals; Chemotactic Factors; Dose-Response Relationship, Drug; Female; Inflammation; Leukocyte Coun | 1993 |
A combined casein-free-nicotinamide diet prevents diabetes in the NOD mouse with minimum insulitis.
Topics: Animals; Caseins; Diabetes Mellitus, Type 1; Diet, Protein-Restricted; Female; Fluorescent Antibody | 1995 |
Islet protective effect of pravastatin from nonspecific inflammation in mouse pancreatic islet isografts.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Diabetes Mellitus | 1996 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibito | 1999 |
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Topics: Animals; Antioxidants; Arthritis, Experimental; Carrageenan; Dose-Response Relationship, Drug; Edema | 2000 |
Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.
Topics: Benzimidazoles; Biomarkers; Calmodulin; Cells, Cultured; Cysteine Proteinase Inhibitors; Dinoproston | 2000 |
Nicotinamide N-oxides as CXCR2 antagonists.
Topics: Autoimmune Diseases; Binding Sites; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Chemotaxi | 2001 |
N1-methylnicotinamide level in the blood after nicotinamide loading as further evidence for malignant tumor burden.
Topics: Animals; Carbon Tetrachloride Poisoning; Cells, Cultured; DNA Replication; Galactosamine; Inflammati | 1991 |
Pharmacologic modulation of acute uveitis with aminonicotinamide.
Topics: 6-Aminonicotinamide; Acute Disease; Animals; Antigens; Arrestin; Ciliary Body; Eye Proteins; Immuniz | 1990 |
Nicotinamide prevents lymphocytic infiltration in submandibular glands but not the appearance of anti-salivary duct antibodies in non-obese diabetic (NOD) mice.
Topics: Animals; Antibody Formation; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Inflam | 1985 |
Modulation of streptozotocin-induced insulitis and hyperglycaemia in the mouse.
Topics: Animals; Diabetes Mellitus, Experimental; Hyperglycemia; Inflammation; Islets of Langerhans; Male; M | 1985 |
[Combined action of penicillin, levomycetin and some water-soluble vitamins on aseptic inflammation and phagocytosis].
Topics: Animals; Ascorbic Acid; Chloramphenicol; Drug Synergism; Female; Folic Acid; Inflammation; Male; Nia | 1966 |