niacinamide has been researched along with Injury, Myocardial Reperfusion in 42 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to assess the cardioprotective effect of intravenous nicorandil, a potassium channel opener, in preventing reperfusion injury in acute myocardial infarction." | 9.08 | Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction. ( Daikoku, S; Goto, Y; Haze, K; Itoh, A; Kobayashi, Y; Miyazaki, S; Nonogi, H; Ohshima, S, 1998) |
| "These experiments were designed to explore the possibility that a K+ channel opener which also donates nitric oxide to the myocardium (nicorandil) may modify ischaemia-induced ventricular arrhythmias in a large animal model." | 7.69 | Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia. ( Györgyi, K; Papp, JG; Parratt, JR; Sakai, K; Vegh, A, 1996) |
| "This study was designed to assess the cardioprotective effect of intravenous nicorandil, a potassium channel opener, in preventing reperfusion injury in acute myocardial infarction." | 5.08 | Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction. ( Daikoku, S; Goto, Y; Haze, K; Itoh, A; Kobayashi, Y; Miyazaki, S; Nonogi, H; Ohshima, S, 1998) |
| "These experiments were designed to explore the possibility that a K+ channel opener which also donates nitric oxide to the myocardium (nicorandil) may modify ischaemia-induced ventricular arrhythmias in a large animal model." | 3.69 | Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia. ( Györgyi, K; Papp, JG; Parratt, JR; Sakai, K; Vegh, A, 1996) |
| "Type 2 diabetes was induced by injection of streptozotocin and nicotinamide." | 1.43 | Effects of Nitrate Intake on Myocardial Ischemia-Reperfusion Injury in Diabetic Rats. ( Bageripour, F; Ghanbari, M; Ghasemi, A; Jeddi, S; Khalifi, S, 2016) |
| "NCX is an attractive target for the treatment of heart failure and ischemia-reperfusion." | 1.33 | Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor. ( Kakefuda, A; Kuramochi, T; Sakamoto, S; Taguchi, T; Tsukamoto, I; Yamada, H, 2005) |
| " Prior exposure to FeSO4/H2O2 produced significant endothelial damage as reflected by the right-ward shift of the dose-response curve of bradykinin-induced endothelium-dependent relaxation." | 1.30 | Hydroxyl radical scavenging effect of nicaraven in myocardial and coronary endothelial preservation and reperfusion injury. ( Alam, MS; Hashimoto, M; Ku, K; Masumura, S; Nakayama, K; Nosaka, S; Saitoh, Y; Tamura, K; Yamauchi, M, 1997) |
| "OH significantly produced right-ward shift of the dose-response curves of the bradykinin-induced endothelium-dependent relaxations (an increase in the ED50 value for bradykinin by 4." | 1.30 | Protective effects of nicaraven, a new hydroxyl radical scavenger, on the endothelial dysfunction after exposure of pig coronary artery to hydroxyl radicals. ( Alam, MS; Hashimoto, M; Hossain, MS; Ku, K; Masumura, S; Nakayama, K; Nosaka, S; Tamura, K; Yamauchi, M, 1998) |
| "TTX and nicorandil decreased arrhythmias, probably by decreasing the Na+ current or by increasing the ATP-sensitive K+ current, respectively." | 1.29 | Prevention of reoxygenation-induced arrhythmias in guinea pig papillary muscles. ( Hayashi, H; Katoh, H; McDonald, TF; Terada, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.52) | 18.7374 |
| 1990's | 26 (61.90) | 18.2507 |
| 2000's | 6 (14.29) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Eltze, T | 1 |
| Boer, R | 1 |
| Wagner, T | 1 |
| Weinbrenner, S | 1 |
| McDonald, MC | 2 |
| Thiemermann, C | 3 |
| Bürkle, A | 1 |
| Klein, T | 1 |
| Wang, ZK | 1 |
| Chen, RR | 1 |
| Li, JH | 1 |
| Chen, JY | 1 |
| Li, W | 1 |
| Niu, XL | 1 |
| Wang, FF | 1 |
| Wang, J | 1 |
| Yang, JX | 1 |
| Zhernakova, NI | 1 |
| Gorbach, TV | 1 |
| Romashchenko, OV | 1 |
| Rumbesht, VV | 1 |
| Wang, H | 1 |
| Liang, X | 1 |
| Luo, G | 1 |
| Ding, M | 1 |
| Liang, Q | 1 |
| Jeddi, S | 1 |
| Khalifi, S | 1 |
| Ghanbari, M | 1 |
| Bageripour, F | 1 |
| Ghasemi, A | 1 |
| Sukhodub, A | 1 |
| Du, Q | 1 |
| Jovanović, S | 1 |
| Jovanović, A | 1 |
| Shinmura, K | 1 |
| Tamaki, K | 1 |
| Sano, M | 1 |
| Nakashima-Kamimura, N | 1 |
| Wolf, AM | 1 |
| Amo, T | 1 |
| Ohta, S | 1 |
| Katsumata, Y | 1 |
| Fukuda, K | 1 |
| Ishiwata, K | 1 |
| Suematsu, M | 1 |
| Adachi, T | 1 |
| Szabó, G | 1 |
| Liaudet, L | 1 |
| Hagl, S | 1 |
| Szabó, C | 1 |
| Kuramochi, T | 1 |
| Kakefuda, A | 1 |
| Yamada, H | 1 |
| Tsukamoto, I | 1 |
| Taguchi, T | 1 |
| Sakamoto, S | 1 |
| L'Abbate, A | 1 |
| Neglia, D | 1 |
| Vecoli, C | 1 |
| Novelli, M | 1 |
| Ottaviano, V | 1 |
| Baldi, S | 1 |
| Barsacchi, R | 1 |
| Paolicchi, A | 1 |
| Masiello, P | 1 |
| Drummond, GS | 1 |
| McClung, JA | 1 |
| Abraham, NG | 1 |
| Qiu, Y | 1 |
| Galiñanes, M | 1 |
| Hearse, DJ | 1 |
| Popescu, LM | 1 |
| Musat, S | 1 |
| Trifan, OC | 1 |
| Leabu, M | 1 |
| Tigaret, CM | 1 |
| Popescu, M | 1 |
| Popescu, A | 1 |
| Hinescu, ME | 1 |
| Moraru, II | 1 |
| Das, DK | 1 |
| Gross, GJ | 6 |
| Yao, Z | 1 |
| Pieper, GM | 3 |
| Auchampach, JA | 5 |
| Iwamoto, T | 1 |
| Miura, T | 1 |
| Urabe, K | 1 |
| Itoya, M | 1 |
| Shimamoto, K | 1 |
| Iimura, O | 1 |
| Orita, H | 5 |
| Fukasawa, M | 5 |
| Hirooka, S | 4 |
| Minowa, T | 1 |
| Uchino, H | 1 |
| Washio, M | 5 |
| Nakaya, H | 1 |
| Warltier, DC | 2 |
| Menasché, P | 1 |
| Kevelaitis, E | 1 |
| Mouas, C | 1 |
| Grousset, C | 1 |
| Piwnica, A | 1 |
| Bloch, G | 1 |
| Hayashi, H | 1 |
| Terada, H | 1 |
| Katoh, H | 1 |
| McDonald, TF | 1 |
| Vegh, A | 1 |
| Györgyi, K | 1 |
| Papp, JG | 1 |
| Sakai, K | 1 |
| Parratt, JR | 1 |
| Nakagawa, C | 1 |
| Asayama, J | 1 |
| Tatsumi, T | 1 |
| Matoba, S | 1 |
| Kobara, M | 1 |
| Tanaka, T | 1 |
| Ohta, B | 1 |
| Kawahara, A | 1 |
| Tsuruyama, K | 1 |
| Katamura, M | 1 |
| Nakagawa, M | 1 |
| Ku, K | 3 |
| Kin, S | 1 |
| Hashimoto, M | 3 |
| Saitoh, Y | 2 |
| Nosaka, S | 3 |
| Iwasaki, S | 1 |
| Alam, MS | 3 |
| Nakayama, K | 3 |
| Yamauchi, M | 2 |
| Masumura, S | 2 |
| Tamura, K | 2 |
| Piriou, V | 1 |
| Ross, S | 1 |
| Pigott, D | 1 |
| Evans, R | 1 |
| Foex, P | 1 |
| Hossain, MS | 1 |
| Kobayashi, Y | 1 |
| Goto, Y | 1 |
| Daikoku, S | 1 |
| Itoh, A | 1 |
| Miyazaki, S | 1 |
| Ohshima, S | 1 |
| Nonogi, H | 1 |
| Haze, K | 1 |
| Shinohara, H | 1 |
| Nishikado, A | 1 |
| Wakatsuki, T | 1 |
| Sakabe, K | 1 |
| Ito, S | 1 |
| Bowes, J | 1 |
| Piper, J | 1 |
| Tavazzi, B | 1 |
| Di Pierro, D | 1 |
| Amorini, AM | 1 |
| Fazzina, G | 1 |
| Galvano, M | 1 |
| Lupi, A | 1 |
| Giardina, B | 1 |
| Lazzarino, G | 1 |
| Cavero, I | 1 |
| Maruyama, M | 1 |
| Shimanuki, T | 3 |
| Abe, H | 4 |
| Kuraoka, S | 3 |
| Zhang, YM | 2 |
| Zhao, DH | 2 |
| Sheng, BH | 2 |
| Inui, K | 2 |
| Kempsford, RD | 1 |
| Hawgood, BJ | 1 |
| Irié, H | 1 |
| Kobayashi, M | 1 |
2 reviews available for niacinamide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Poly(ADP-ribose) polymerase activation in the reperfused myocardium.
Topics: Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Models, Animal; Myocardial I | 2004 |
[Potential role of ATP-sensitive K+ channels in ischemia- and reperfusion-induced arrhythmias].
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; G | 1993 |
1 trial available for niacinamide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Cardioprotective effect of intravenous nicorandil in patients with successful reperfusion for acute myocardial infarction.
Topics: Acute Disease; Anti-Arrhythmia Agents; Humans; Injections, Intravenous; Myocardial Infarction; Myoca | 1998 |
39 other studies available for niacinamide and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male | 2008 |
Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway.
Topics: Animals; Cardiotonic Agents; Enzyme Inhibitors; Heart; Inflammasomes; Inflammation; Isoflavones; Mal | 2020 |
Age-related features of Cytoflavin effectiveness during experimental myocardial ischemia.
Topics: Adenosine Triphosphate; Age Factors; Animals; Cardiotonic Agents; Drug Combinations; Enzyme Activati | 2014 |
Protection effect of nicotinamide on cardiomyoblast hypoxia/re-oxygenation injury: study of cellular mitochondrial metabolism.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Citric Acid Cycle; Dose-Response Relationship, D | 2016 |
Effects of Nitrate Intake on Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Topics: Animals; Cardiotonic Agents; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetes Mellitus, T | 2016 |
Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: a crucial role for cardiac SUR2A.
Topics: Animals; ATP-Binding Cassette Transporters; Cardiotonic Agents; KATP Channels; Male; Mice; Mice, Inb | 2010 |
Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain.
Topics: Acetylation; Animals; Antioxidants; Blotting, Western; Caloric Restriction; Cells, Cultured; Disease | 2011 |
Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor.
Topics: Administration, Oral; Animals; Biological Availability; Calcium; Calcium Channel Blockers; Cytochrom | 2005 |
Beneficial effect of heme oxygenase-1 expression on myocardial ischemia-reperfusion involves an increase in adiponectin in mildly diabetic rats.
Topics: Adiponectin; Animals; bcl-X Protein; Cardiovascular Agents; Coronary Vessels; Diabetes Mellitus, Exp | 2007 |
Protective effect of nicorandil as an additive to the solution for continuous warm cardioplegia.
Topics: Animals; Cardioplegic Solutions; Coronary Circulation; Dose-Response Relationship, Drug; Heart; Hear | 1995 |
K(+)-channel openers protect the myocardium against ischemia-reperfusion injury.
Topics: Animals; In Vitro Techniques; Lipid Metabolism; Myocardial Ischemia; Myocardial Reperfusion Injury; | 1994 |
The ATP-regulated potassium channel in ischemia-reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Dogs; Glyburide; Ion Channel Gating; Myocardial Contraction; Myocar | 1994 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating | 1993 |
Prevention of postischemic reperfusion injury: the improvement of myocardial tissue blood flow after ischemia by terminal nicorandil-Mg cardioplegia.
Topics: Animals; Blood Flow Velocity; Carbon Dioxide; Cardioplegic Solutions; Coronary Vessels; Dogs; Glucos | 1993 |
Anti-ischaemic actions of potassium channel openers in experimental myocardial ischaemia/reperfusion injury in dogs.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; | 1993 |
Relationship of severity of myocardial stunning to ATP dependent potassium channel modulation.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Glyburide; Myocardial Contraction; Myoc | 1993 |
Preconditioning with potassium channel openers. A new concept for enhancing cardioplegic protection?
Topics: Animals; Coronary Circulation; Glyburide; Heart Arrest, Induced; Male; Myocardial Ischemia; Myocardi | 1995 |
Prevention of reoxygenation-induced arrhythmias in guinea pig papillary muscles.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Gallopamil; Guine | 1996 |
Nicorandil suppressed ventricular arrhythmias in a canine model of myocardial ischaemia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Circulation; Dogs; E | 1996 |
Effects of glibenclamide and nicorandil in post-ischaemic contractile dysfunction of perfused hearts in normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cardiac Volume; Creatine Kinase; Glyburide; Heart Rate; Hemodynamics; Hyper | 1996 |
The role of a hydroxyl radical scavenger (nicaraven) in recovery of cardiac function following preservation and reperfusion.
Topics: Animals; Biomarkers; Body Water; Catalase; Creatine Kinase; Free Radical Scavengers; Heart; Hydroxyl | 1996 |
Hydroxyl radical scavenging effect of nicaraven in myocardial and coronary endothelial preservation and reperfusion injury.
Topics: Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Ferrous Compounds; Free Radi | 1997 |
Beneficial effect of concomitant administration of isoflurane and nicorandil.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Drug Therapy, Co | 1997 |
Protective effects of nicaraven, a new hydroxyl radical scavenger, on the endothelial dysfunction after exposure of pig coronary artery to hydroxyl radicals.
Topics: Animals; Bradykinin; Coronary Vessels; Dimethyl Sulfoxide; Dinoprost; Endothelium, Vascular; Ferrous | 1998 |
The effects of nicorandil on electrophysiological changes in acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Dogs; Drug Evaluation, Precl | 1998 |
Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress.
Topics: Aminobenzoates; Animals; Benzamides; Cell Death; Cell Line; Enzyme Inhibitors; Heart; Hydrogen Perox | 1999 |
Direct NAD(P)H hydrolysis into ADP-ribose(P) and nicotinamide induced by reactive oxygen species: a new mechanism of oxygen radical toxicity.
Topics: Adenosine Diphosphate Ribose; Animals; Free Radicals; Hydrolysis; In Vitro Techniques; Male; Models, | 2000 |
Inhibition of the activity of poly (ADP-ribose) polymerase in ischemia-reperfusion injury.
Topics: Animals; DNA Damage; Drug Design; Energy Metabolism; Enzyme Inhibitors; Feedback; Humans; Ischemia; | 2000 |
Nicorandil attenuates myocardial dysfunction associated with transient ischemia by opening ATP-dependent potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Dogs; Female; | 1992 |
Cardioprotective effects of nicorandil.
Topics: Animals; Benzopyrans; Coronary Circulation; Dihydropyridines; Dogs; Female; Heart; In Vitro Techniqu | 1992 |
Accelerated myocardial metabolic and functional recovery with terminal nicorandil-Mg cardioplegia in heart transplantation.
Topics: Animals; Coronary Circulation; Dogs; Heart Arrest, Induced; Heart Transplantation; Magnesium; Myocar | 1991 |
[Protective effects of nicorandil on myocardial mitochondria function during ischemia and reperfusion].
Topics: Animals; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Oxidativ | 1991 |
[Preventive effect of post-ischemic reperfusion injury by terminal Nicorandil-Mg cardioplegia].
Topics: Heart Arrest, Induced; Heart Valve Diseases; Humans; Myocardial Reperfusion Injury; Myocardium; Niac | 1991 |
[Preventive effect of post-ischemic reperfusion injury by terminal Nicorandil-Mg cardioplegia].
Topics: Animals; Dogs; Heart Arrest, Induced; Magnesium; Myocardial Reperfusion Injury; Niacinamide; Nicoran | 1990 |
[Protective effects of nicorandil on lipid peroxidation in ischemic and reperfused myocardium of rabbits].
Topics: Animals; Creatine Kinase; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Reperfusion Injury; | 1990 |
Assessment of the antiarrhythmic activity of nicorandil during myocardial ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Disease; Ele | 1989 |
Effect of cyclooxygenase blockade on the beneficial actions of nicorandil in the stunned myocardium of dogs.
Topics: Animals; Blood Pressure; Cardiomyopathies; Coronary Circulation; Cyclooxygenase Inhibitors; Dinopros | 1989 |
Experimental studies on ischemic injury and reperfusion injury to the cardiac sarcoplasmic reticulum--the myocardial protective effect of nicorandil.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Cardioplegic Solutions; Cardiopulmonary Bypass; Co | 1988 |
[Accelerated myocardial metabolic and functional recovery with terminal nicorandil-mg cardioplegia in experimental heart transplantation].
Topics: Animals; Cardioplegic Solutions; Dogs; Heart; Heart Arrest, Induced; Heart Transplantation; Magnesiu | 1988 |