niacinamide has been researched along with Infarction, Middle Cerebral Artery in 11 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic stroke is one of the leading causes of human death and disability." | 1.72 | Acutely Inhibiting AQP4 With TGN-020 Improves Functional Outcome by Attenuating Edema and Peri-Infarct Astrogliosis After Cerebral Ischemia. ( Hao, X; Li, C; Lin, L; Ren, Y; Sun, C; Tian, J; Yang, Y; Yin, L; Zhang, X, 2022) |
| "Hyperglycemia was induced in rats by the administration of nicotinamide and streptozotocin." | 1.51 | Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats. ( Detante, O; Diekhorst, L; Díez-Tejedor, E; Fuentes, B; Gómez-de Frutos, MC; Gutiérrez-Fernández, M; Jolkkonen, J; Laso-García, F; Martínez-Arroyo, A; Moisan, A; Otero-Ortega, L, 2019) |
| "Stroke is a leading cause of morbidity and mortality." | 1.46 | Nicotinamide Administration Improves Remyelination after Stroke. ( Ding, J; Luan, Y; Qian, C; Teng, GJ; Wang, C; Zhang, Y; Zhao, Z, 2017) |
| "TGN-020 significantly reduced oedema, glial scar, albumin effusion, and apoptosis, at both 3 and 7 days after MCAO." | 1.46 | Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways. ( Balsanu, TA; Bogdan, C; Carare, RO; Divan, T; Margaritescu, C; Mogoanta, L; Muresanu, DF; Pirici, D; Pirici, I; Vitalie, V, 2017) |
| "Focal cerebral ischemia was induced by middle cerebral artery occlusion (MCAO)." | 1.37 | Proteomic identification of proteins differentially expressed by nicotinamide in focal cerebral ischemic injury. ( Kim, MO; Koh, PO; Sung, JH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YH | 1 |
| Zhao, JH | 1 |
| Zong, WF | 1 |
| Wei, XJ | 1 |
| Xu, Z | 1 |
| Yuan, Y | 1 |
| Jiang, YF | 1 |
| Luo, X | 1 |
| Wang, W | 1 |
| Qu, WS | 1 |
| Sun, C | 1 |
| Lin, L | 1 |
| Yin, L | 1 |
| Hao, X | 1 |
| Tian, J | 1 |
| Zhang, X | 1 |
| Ren, Y | 1 |
| Li, C | 1 |
| Yang, Y | 1 |
| Wang, C | 1 |
| Zhang, Y | 1 |
| Ding, J | 1 |
| Zhao, Z | 1 |
| Qian, C | 1 |
| Luan, Y | 1 |
| Teng, GJ | 1 |
| Pirici, I | 1 |
| Balsanu, TA | 1 |
| Bogdan, C | 1 |
| Margaritescu, C | 1 |
| Divan, T | 1 |
| Vitalie, V | 1 |
| Mogoanta, L | 1 |
| Pirici, D | 1 |
| Carare, RO | 1 |
| Muresanu, DF | 1 |
| Gómez-de Frutos, MC | 1 |
| Laso-García, F | 1 |
| Diekhorst, L | 1 |
| Otero-Ortega, L | 1 |
| Fuentes, B | 1 |
| Jolkkonen, J | 1 |
| Detante, O | 1 |
| Moisan, A | 1 |
| Martínez-Arroyo, A | 1 |
| Díez-Tejedor, E | 1 |
| Gutiérrez-Fernández, M | 1 |
| Koh, PO | 3 |
| Zuloaga, KL | 1 |
| Krasnow, SM | 1 |
| Zhu, X | 1 |
| Zhang, W | 1 |
| Jouihan, SA | 1 |
| Shangraw, RE | 1 |
| Alkayed, NJ | 1 |
| Marks, DL | 1 |
| Sung, JH | 1 |
| Kim, MO | 1 |
| Gupta, S | 1 |
| Kaul, CL | 1 |
| Sharma, SS | 1 |
| Lee, EJ | 1 |
| Wu, TS | 1 |
| Chang, GL | 1 |
| Li, CY | 1 |
| Chen, TY | 1 |
| Lee, MY | 1 |
| Chen, HY | 1 |
| Maynard, KI | 1 |
11 other studies available for niacinamide and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Acute Treatment with Nicotinamide Riboside Chloride Reduces Hippocampal Damage and Preserves the Cognitive Function of Mice with Ischemic Injury.
Topics: Animals; Chlorides; Cognition; Hippocampus; Infarction, Middle Cerebral Artery; Mice; NAD; Niacinami | 2022 |
Acutely Inhibiting AQP4 With TGN-020 Improves Functional Outcome by Attenuating Edema and Peri-Infarct Astrogliosis After Cerebral Ischemia.
Topics: Animals; Aquaporin 4; Brain Edema; Brain Ischemia; Gliosis; Infarction, Middle Cerebral Artery; Magn | 2022 |
Nicotinamide Administration Improves Remyelination after Stroke.
Topics: Animals; Demyelinating Diseases; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Niaci | 2017 |
Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways.
Topics: Albumins; Animals; Apoptosis; Aquaporin 4; Arteries; Brain; Brain Ischemia; Caspase 3; Disease Model | 2017 |
Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats.
Topics: Administration, Intravenous; Animals; Brain; Disease Models, Animal; Doublecortin Protein; Humans; H | 2019 |
Nicotinamide attenuates the injury-induced decrease of hippocalcin in ischemic brain injury.
Topics: Animals; Down-Regulation; Hippocalcin; Infarction, Middle Cerebral Artery; Male; Neuroprotective Age | 2013 |
Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke.
Topics: Analysis of Variance; Animals; Benzoates; Blood Glucose; Blotting, Western; Brain; Diabetes Mellitus | 2014 |
Proteomic identification of proteins differentially expressed by nicotinamide in focal cerebral ischemic injury.
Topics: Animals; Cerebral Cortex; Chaperonin 60; Electrophoresis, Gel, Two-Dimensional; Infarction, Middle C | 2011 |
Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation.
Topics: 14-3-3 Proteins; Animals; bcl-Associated Death Protein; Cell Survival; Drug Evaluation, Preclinical; | 2011 |
Neuroprotective effect of combination of poly (ADP-ribose) polymerase inhibitor and antioxidant in middle cerebral artery occlusion induced focal ischemia in rats.
Topics: Animals; Antioxidants; Benzamides; Brain Ischemia; Disease Models, Animal; Drug Combinations; Drug T | 2004 |
Delayed treatment with nicotinamide inhibits brain energy depletion, improves cerebral microperfusion, reduces brain infarct volume, but does not alter neurobehavioral outcome following permanent focal cerebral ischemia in Sprague Dawley rats.
Topics: Adenine; Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Brain Chemistry; Cerebrovascular | 2006 |