niacinamide has been researched along with Idiopathic Pulmonary Fibrosis in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Idiopathic Pulmonary Fibrosis: A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.
| Excerpt | Relevance | Reference |
|---|---|---|
| " GBT1118 is a novel orally bioavailable small molecule that binds to hemoglobin and produces a concentration-dependent left shift of the oxygen-hemoglobin dissociation curve with subsequent increase in hemoglobin-oxygen affinity and arterial oxygen loading." | 1.43 | Increased hemoglobin-oxygen affinity ameliorates bleomycin-induced hypoxemia and pulmonary fibrosis. ( Dufu, K; Geng, X; Hutchaleelaha, A; Lehrer-Graiwer, J; Li, CM; Li, Z; Oksenberg, D; Patel, MP; Vlahakis, N; Xu, Q, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, YL | 1 |
| Zhang, X | 1 |
| Bai, J | 1 |
| Gai, L | 1 |
| Ye, XL | 1 |
| Zhang, L | 1 |
| Xu, Q | 2 |
| Zhang, YX | 1 |
| Xu, L | 1 |
| Li, HP | 1 |
| Ding, X | 1 |
| Geng, X | 1 |
| Dufu, K | 1 |
| Hutchaleelaha, A | 1 |
| Li, Z | 1 |
| Li, CM | 1 |
| Patel, MP | 1 |
| Vlahakis, N | 1 |
| Lehrer-Graiwer, J | 1 |
| Oksenberg, D | 1 |
2 other studies available for niacinamide and Idiopathic Pulmonary Fibrosis
| Article | Year |
|---|---|
Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial-mesenchymal transition and fibroblast activation.
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Bleomycin; Cell Line, Tumor; Cell Proliferation; Epit | 2013 |
Increased hemoglobin-oxygen affinity ameliorates bleomycin-induced hypoxemia and pulmonary fibrosis.
Topics: Administration, Oral; Animals; Benzaldehydes; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Dys | 2016 |