niacinamide has been researched along with Hyperpigmentation in 14 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In both studies, the combination formulation was significantly more effective than the vehicle and the 5% niacinamide formulation in reducing the appearance of hyperpigmentation after 8 weeks." | 9.14 | Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide. ( Bissett, DL; Hakozaki, T; Kelm, GR; Li, J; Miyamoto, K; Raleigh, PS; Robinson, LR, 2009) |
| "The aim of this study was to prepare niacinamide (NA) imprinted biomaterials for treating hyperpigmentation using mungbean starch (MS), PVA, and plasticizers (glycerol (GL) and citric acid (CA))." | 8.31 | Preparation of niacinamide imprinted starch-based biomaterials for treating of hyperpigmentation. ( Ahn, G; Lee, SY; Yoon, SD, 2023) |
| "In both studies, the combination formulation was significantly more effective than the vehicle and the 5% niacinamide formulation in reducing the appearance of hyperpigmentation after 8 weeks." | 5.14 | Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide. ( Bissett, DL; Hakozaki, T; Kelm, GR; Li, J; Miyamoto, K; Raleigh, PS; Robinson, LR, 2009) |
| "To investigate the effects of niacinamide on melanogenesis in vitro and on facial hyperpigmentation and skin colour in vivo in Japanese women." | 5.10 | The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. ( Bissett, DL; Boissy, RE; Chhoa, M; Greatens, A; Hakozaki, T; Hillebrand, GG; Matsubara, A; Minwalla, L; Miyamoto, K; Zhuang, J, 2002) |
| "The aim of this study was to prepare niacinamide (NA) imprinted biomaterials for treating hyperpigmentation using mungbean starch (MS), PVA, and plasticizers (glycerol (GL) and citric acid (CA))." | 4.31 | Preparation of niacinamide imprinted starch-based biomaterials for treating of hyperpigmentation. ( Ahn, G; Lee, SY; Yoon, SD, 2023) |
| "Pellagra is a nutritional disease caused by the deficiency of niacin." | 3.79 | Pellagra revealing a congenital duodenal diaphragm in an adult. ( Ahmed, S; Farah, J; Haykel, B; Houcine, M; Khouloud, B; Yacine, BS; Zoubeir, BS, 2013) |
| "Hyperpigmentation has traditionally been a relatively difficult condition to treat, especially in darker racial ethnic groups." | 2.48 | Topical treatment of hyperpigmentation disorders. ( Horwitz, S; Rendon, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Shariff, R | 1 |
| Du, Y | 1 |
| Dutta, M | 1 |
| Kumar, S | 1 |
| Thimmaiah, S | 1 |
| Doraiswamy, C | 1 |
| Kumari, A | 1 |
| Kale, V | 1 |
| Nair, N | 1 |
| Zhang, S | 1 |
| Joshi, M | 1 |
| Santhanam, U | 1 |
| Qiang, Q | 1 |
| Damodaran, A | 1 |
| Lee, SY | 1 |
| Ahn, G | 1 |
| Yoon, SD | 1 |
| Draelos, ZD | 1 |
| Diaz, I | 1 |
| Desai, S | 1 |
| Ayres, E | 1 |
| Bak, H | 1 |
| Manco, M | 1 |
| Lynch, S | 1 |
| Raab, S | 1 |
| Du, A | 1 |
| Green, D | 1 |
| Skobowiat, C | 1 |
| Wangari-Talbot, J | 1 |
| Zheng, Q | 1 |
| Rendon, M | 1 |
| Horwitz, S | 1 |
| Lee, DH | 1 |
| Oh, IY | 1 |
| Koo, KT | 1 |
| Suk, JM | 1 |
| Jung, SW | 1 |
| Park, JO | 1 |
| Kim, BJ | 1 |
| Choi, YM | 1 |
| Kimball, AB | 1 |
| Kaczvinsky, JR | 1 |
| Li, J | 3 |
| Robinson, LR | 3 |
| Matts, PJ | 1 |
| Berge, CA | 1 |
| Miyamoto, K | 5 |
| Bissett, DL | 4 |
| Raleigh, PS | 2 |
| Hakozaki, T | 5 |
| Kelm, GR | 2 |
| Kim, B | 1 |
| Kim, JE | 1 |
| Lee, SM | 1 |
| Lee, SH | 1 |
| Lee, JW | 1 |
| Kim, MK | 1 |
| Lee, KJ | 1 |
| Kim, H | 1 |
| Lee, JD | 1 |
| Choi, KY | 1 |
| Khouloud, B | 1 |
| Haykel, B | 1 |
| Ahmed, S | 1 |
| Houcine, M | 1 |
| Yacine, BS | 1 |
| Farah, J | 1 |
| Zoubeir, BS | 1 |
| Greatens, A | 2 |
| Koshoffer, A | 1 |
| Epstein, H | 1 |
| Schwemberger, S | 1 |
| Babcock, G | 1 |
| Bissett, D | 1 |
| Takiwaki, H | 2 |
| Arase, S | 2 |
| Wickett, RR | 1 |
| Boissy, RE | 2 |
| Sato, Y | 1 |
| Minwalla, L | 1 |
| Zhuang, J | 1 |
| Chhoa, M | 1 |
| Matsubara, A | 1 |
| Hillebrand, GG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improved Skin Whitening Outcomes Associated With Nicotinamide Fortified Consumption in 30 to 50-Year-old Women, a Double Blind, Control and Randomized Study[NCT05696938] | 70 participants (Actual) | Interventional | 2023-02-16 | Completed | |||
| A Randomized, Double Blind, Controlled Study of Improved Skin Anti-aging Outcomes Associated With Collagen Fortified Consumption In 30 to 50-Year-old Women[NCT05670977] | 70 participants (Actual) | Interventional | 2023-01-16 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for niacinamide and Hyperpigmentation
| Article | Year |
|---|---|
Topical treatment of hyperpigmentation disorders.
Topics: Administration, Topical; Adrenal Cortex Hormones; Arbutin; Chromones; Drug Combinations; Free Radica | 2012 |
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine.
Topics: Acetylglucosamine; Administration, Topical; Adult; Aged; Asian People; Dose-Response Relationship, D | 2007 |
9 trials available for niacinamide and Hyperpigmentation
| Article | Year |
|---|---|
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation | 2022 |
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation | 2022 |
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation | 2022 |
Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide.
Topics: Aging; Hexylresorcinol; Humans; Hyperpigmentation; Niacinamide; Skin Pigmentation | 2022 |
Effect of a Tranexamic Acid, Kojic Acid, and Niacinamide Containing Serum on Facial Dyschromia: A Clinical Evaluation
Topics: Administration, Cutaneous; Adult; Dermatologic Agents; Facial Dermatoses; Female; Humans; Hyperpigme | 2019 |
Reduction in facial hyperpigmentation after treatment with a combination of topical niacinamide and tranexamic acid: a randomized, double-blind, vehicle-controlled trial.
Topics: Administration, Topical; Adult; Antifibrinolytic Agents; Delayed-Action Preparations; Dermatologic A | 2014 |
Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial.
Topics: Acetylglucosamine; Administration, Topical; Adult; Double-Blind Method; Drug Therapy, Combination; F | 2010 |
Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide.
Topics: Administration, Topical; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Facial Dermato | 2009 |
N-Nicotinoyl dopamine, a novel niacinamide derivative, retains high antioxidant activity and inhibits skin pigmentation.
Topics: Animals; Antioxidants; Bleaching Agents; Cell Line; Cell Line, Tumor; Dopamine; Humans; Hyperpigment | 2011 |
Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible.
Topics: Administration, Topical; Adult; Cell Survival; Cells, Cultured; Coculture Techniques; Double-Blind M | 2005 |
Ultrasound enhanced skin-lightening effect of vitamin C and niacinamide.
Topics: Adult; Ascorbic Acid; Combined Modality Therapy; Dermatologic Agents; Female; Humans; Hyperpigmentat | 2006 |
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
Topics: Adolescent; Adult; Cell Culture Techniques; Coculture Techniques; Dose-Response Relationship, Drug; | 2002 |
3 other studies available for niacinamide and Hyperpigmentation
| Article | Year |
|---|---|
Preparation of niacinamide imprinted starch-based biomaterials for treating of hyperpigmentation.
Topics: Antioxidants; Biocompatible Materials; Humans; Hyperpigmentation; Melanins; Monophenol Monooxygenase | 2023 |
The clinical benefit of a multimodal topical approach to treating skin dyspigmentation.
Topics: Dermatologic Agents; Female; Humans; Hyperpigmentation; Niacinamide; Tranexamic Acid; Treatment Outc | 2023 |
Pellagra revealing a congenital duodenal diaphragm in an adult.
Topics: Adult; Diaphragm; Duodenal Obstruction; Female; Humans; Hyperpigmentation; Malnutrition; Niacinamide | 2013 |