niacinamide has been researched along with Huntington Disease in 9 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Fathi, M | 1 |
| Vakili, K | 1 |
| Yaghoobpoor, S | 1 |
| Tavasol, A | 1 |
| Jazi, K | 1 |
| Hajibeygi, R | 1 |
| Shool, S | 1 |
| Sodeifian, F | 1 |
| Klegeris, A | 1 |
| McElhinney, A | 1 |
| Tavirani, MR | 1 |
| Sayehmiri, F | 1 |
| Whittaker, DS | 1 |
| Wang, HB | 1 |
| Loh, DH | 1 |
| Cachope, R | 1 |
| Colwell, CS | 1 |
| Sidhu, A | 1 |
| Diwan, V | 1 |
| Kaur, H | 1 |
| Bhateja, D | 1 |
| Singh, CK | 1 |
| Sharma, S | 1 |
| Padi, SSV | 1 |
| Naia, L | 1 |
| Rosenstock, TR | 1 |
| Oliveira, AM | 1 |
| Oliveira-Sousa, SI | 1 |
| Caldeira, GL | 1 |
| Carmo, C | 1 |
| Laço, MN | 1 |
| Hayden, MR | 1 |
| Oliveira, CR | 1 |
| Rego, AC | 1 |
| Hathorn, T | 1 |
| Snyder-Keller, A | 1 |
| Messer, A | 1 |
| Sorolla, MA | 1 |
| Nierga, C | 1 |
| Rodríguez-Colman, MJ | 1 |
| Reverter-Branchat, G | 1 |
| Arenas, A | 1 |
| Tamarit, J | 1 |
| Ros, J | 1 |
| Cabiscol, E | 1 |
| Sheline, CT | 1 |
| Zhu, J | 1 |
| Zhang, W | 1 |
| Shi, C | 1 |
| Cai, AL | 1 |
| Beal, MF | 1 |
| Hankes, LV | 1 |
| Coenen, HH | 1 |
| Rota, E | 1 |
| Langen, KJ | 1 |
| Herzog, H | 1 |
| Wutz, W | 1 |
| Stoecklin, G | 1 |
| Feinendegen, LE | 1 |
2 reviews available for niacinamide and Huntington Disease
| Article | Year |
|---|---|
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleac | 2022 |
Neurochemistry and toxin models in Huntington's disease.
Topics: Animals; Coenzymes; Disease Models, Animal; Energy Metabolism; Humans; Huntington Disease; Mitochond | 1994 |
7 other studies available for niacinamide and Huntington Disease
| Article | Year |
|---|---|
Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's disease.
Topics: Animals; Benzazepines; Cognition; Disease Models, Animal; Drug Administration Schedule; Histamine H3 | 2017 |
Nicotinamide reverses behavioral impairments and provides neuroprotection in 3-nitropropionic acid induced animal model ofHuntington's disease: implication of oxidative stress- poly(ADP- ribose) polymerase pathway.
Topics: Animals; Dose-Response Relationship, Drug; Huntington Disease; Male; Neuroprotection; Niacinamide; N | 2018 |
Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models.
Topics: Animals; Corpus Striatum; Disease Models, Animal; DNA, Mitochondrial; Humans; Huntington Disease; Me | 2017 |
Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Humans; Huntington Disea | 2011 |
Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.
Topics: Humans; Huntington Disease; Mutant Proteins; Mutation; Niacinamide; Oxidative Stress; Peptides; Sacc | 2011 |
Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carrier Proteins; Cation Transport Proteins; | 2013 |
Effect of Huntington's and Alzheimer's diseases on the transport of nicotinic acid or nicotinamide across the human blood-brain barrier.
Topics: Alzheimer Disease; Blood-Brain Barrier; Brain; Humans; Huntington Disease; Niacin; Niacinamide; Tomo | 1991 |