niacinamide has been researched along with Hepatic Insufficiency in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Hepatic Insufficiency: Conditions in which the LIVER functions fall below the normal ranges. Severe hepatic insufficiency may cause LIVER FAILURE or DEATH. Treatment may include LIVER TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sorafenib was administered as a 400-mg dose on day 1 for PK, and continuous daily dosing started on day 8." | 2.74 | Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. ( Abou-Alfa, G; Dees, EC; Desai, A; Edelman, MJ; Fakih, MG; Frank, RC; Hohl, RJ; Hollis, DR; Hwang, J; Kennedy, EB; Lewis, LD; Millard, F; Miller, AA; Murry, DJ; Owzar, K; Ratain, MJ; Villalona-Calero, MA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, AA | 1 |
| Murry, DJ | 1 |
| Owzar, K | 1 |
| Hollis, DR | 1 |
| Kennedy, EB | 1 |
| Abou-Alfa, G | 1 |
| Desai, A | 1 |
| Hwang, J | 1 |
| Villalona-Calero, MA | 1 |
| Dees, EC | 1 |
| Lewis, LD | 1 |
| Fakih, MG | 1 |
| Edelman, MJ | 1 |
| Millard, F | 1 |
| Frank, RC | 1 |
| Hohl, RJ | 1 |
| Ratain, MJ | 1 |
| BARTOLOMEI, G | 1 |
| ROSSI, M | 1 |
1 trial available for niacinamide and Hepatic Insufficiency
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Fema | 2009 |
1 other study available for niacinamide and Hepatic Insufficiency
| Article | Year |
|---|---|
[Liver function test in pregnancy; effect of trigonellamide (N1-methylnicotinamide chloride) on pyruvic, lactic, and amino acids in the blood in liver insufficiency in pregnancy].
Topics: Amino Acids; Chlorides; Hepatic Insufficiency; Liver Function Tests; Niacin; Niacinamide; Nicotinic | 1953 |