Compounds > niacinamide
Page last updated: 2024-10-19

niacinamide and HIV Coinfection

niacinamide has been researched along with HIV Coinfection in 23 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"To report the real-life results of sorafenib use in a cohort of HIV-infected patients with hepatocellular carcinoma (HCC)."9.24Real-life experience with sorafenib for the treatment of hepatocellular carcinoma in HIV-infected patients. ( Delgado-Fernández, M; Galindo, MJ; García, MA; Garcia-Deltoro, M; Ibarra, S; Merchante, N; Merino, E; Mínguez, C; Montero-Alonso, M; Pineda, JA; Revollo, B; Rivero-Juárez, A; Rodríguez-Arrondo, F; Romero-Palacios, A; Téllez, F, 2017)
"Few data are available on the safety and efficacy of sorafenib in HIV-infected patients with unresectable hepatocellular carcinoma (HIV-u-HCC) and concomitant highly active antiretroviral therapy (HAART)."7.79Sorafenib for the treatment of unresectable hepatocellular carcinoma in HIV-positive patients. ( Bearz, A; Berretta, M; Cacopardo, B; Dal Maso, L; De Re, V; Di Benedetto, F; Facchini, G; Fiorica, F; Garlassi, E; Lleshi, A; Nasti, G; Spina, M; Tirelli, U, 2013)
"To report the real-life results of sorafenib use in a cohort of HIV-infected patients with hepatocellular carcinoma (HCC)."5.24Real-life experience with sorafenib for the treatment of hepatocellular carcinoma in HIV-infected patients. ( Delgado-Fernández, M; Galindo, MJ; García, MA; Garcia-Deltoro, M; Ibarra, S; Merchante, N; Merino, E; Mínguez, C; Montero-Alonso, M; Pineda, JA; Revollo, B; Rivero-Juárez, A; Rodríguez-Arrondo, F; Romero-Palacios, A; Téllez, F, 2017)
"Few data are available on the safety and efficacy of sorafenib in HIV-infected patients with unresectable hepatocellular carcinoma (HIV-u-HCC) and concomitant highly active antiretroviral therapy (HAART)."3.79Sorafenib for the treatment of unresectable hepatocellular carcinoma in HIV-positive patients. ( Bearz, A; Berretta, M; Cacopardo, B; Dal Maso, L; De Re, V; Di Benedetto, F; Facchini, G; Fiorica, F; Garlassi, E; Lleshi, A; Nasti, G; Spina, M; Tirelli, U, 2013)
"tuberculosis and HIV are uncommon."2.42Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus. ( Murray, MF, 2003)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's5 (21.74)29.6817
2010's13 (56.52)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Pan, B1
Lv, M1
Du, H1
Zhao, D1
Lu, K1
Samer, S1
Namiyama, G1
Oshiro, T1
Arif, MS1
Cardoso da Silva, W1
Sucupira, MCA1
Janini, LM1
Diaz, RS1
Tian, Y1
Liu, Z2
Liu, J1
Huang, B1
Kang, D1
Zhang, H1
De Clercq, E2
Daelemans, D1
Pannecouque, C2
Lee, KH1
Chen, CH1
Zhan, P2
Liu, X2
Mancuso, A1
Zavaglia, C1
Bai, F1
Puoti, M1
Belli, LS1
Chen, W1
Bipath, P1
Levay, PF1
Viljoen, M1
Zhou, X1
Fang, W1
Tan, S1
Lin, X1
Xun, T1
Yang, B1
Liu, S1
Liu, Y1
Merchante, N1
Ibarra, S1
Revollo, B1
Rodríguez-Arrondo, F1
Merino, E1
Delgado-Fernández, M1
Montero-Alonso, M1
Téllez, F1
Galindo, MJ1
Rivero-Juárez, A1
García, MA1
Mínguez, C1
Romero-Palacios, A1
Garcia-Deltoro, M1
Pineda, JA1
Dika, IE1
Harding, JJ1
Abou-Alfa, GK1
Schemies, J1
Uciechowska, U1
Sippl, W1
Jung, M1
Perboni, G1
Costa, P1
Fibbia, GC1
Morandini, B1
Scalzini, A1
Tagliani, A1
Cengarle, R1
Aitini, E1
Chelis, L1
Ntinos, N1
Souftas, V1
Deftereos, S1
Xenidis, N1
Chamalidou, E1
Maltezos, E1
Kakolyris, S1
Gómez Rodríguez, R1
Romero Gutiérrez, M1
González de Frutos, C1
de Artaza Varasa, T1
de la Cruz Perez, G1
Ciampi Dopazo, JJ1
Lanciego Pérez, C1
Gómez Moreno, AZ1
Berretta, M1
Di Benedetto, F1
Dal Maso, L1
Cacopardo, B1
Nasti, G1
Facchini, G1
Bearz, A1
Spina, M1
Garlassi, E1
De Re, V1
Fiorica, F1
Lleshi, A1
Tirelli, U1
Murray, MF4
Tremeschin, MH1
Cervi, MC1
Camelo Júnior, JS1
Negrini, BV1
Martinez, FE1
Motta, F1
Meirelles, MS1
Vanucchhi, H1
Monteiro, JP1
Ayouba, A1
Cannou, C1
Nugeyre, MT1
Barré-Sinoussi, F1
Menu, E1
Nghiem, M1
Srinivasan, A2
Cossarizza, A1
Mussini, C1
Mongiardo, N1
Borghi, V1
Sabbatini, A1
De Rienzo, B1
Franceschi, C1
Savarino, A1
Martini, C1
Orofino, GC1
Cantamessa, C1
Castelli, L1
Pich, PG1
Sinicco, A1
Pugliese, A1
Trkola, A1
Kuhmann, SE1
Strizki, JM1
Maxwell, E1
Ketas, T1
Morgan, T1
Pugach, P1
Xu, S1
Wojcik, L1
Tagat, J1
Palani, A1
Shapiro, S1
Clader, JW1
McCombie, S1
Reyes, GR1
Baroudy, BM1
Moore, JP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hepatocellular Carcinoma in HIV-infected Patients[NCT02785835]477 participants (Actual)Observational2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for niacinamide and HIV Coinfection

ArticleYear
Hepatocellular carcinoma in patients with HIV.
    Current opinion in HIV and AIDS, 2017, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coinfection; Hepatitis B, Chronic; Hepatitis C, Ch

2017
NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets.
    Medicinal research reviews, 2010, Volume: 30, Issue:6

    Topics: Animals; Epigenesis, Genetic; HIV Infections; Humans; Inhibitory Concentration 50; Models, Chemical;

2010
Nicotinamide: an oral antimicrobial agent with activity against both Mycobacterium tuberculosis and human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Feb-15, Volume: 36, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; HIV; HIV Infections; HIV-1; Humans; Mycobacterium tube

2003
Tryptophan depletion and HIV infection: a metabolic link to pathogenesis.
    The Lancet. Infectious diseases, 2003, Volume: 3, Issue:10

    Topics: Anti-HIV Agents; HIV Infections; Humans; Niacinamide; Tryptophan

2003

Trials

1 trial available for niacinamide and HIV Coinfection

ArticleYear
Real-life experience with sorafenib for the treatment of hepatocellular carcinoma in HIV-infected patients.
    AIDS (London, England), 2017, 01-02, Volume: 31, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Drug-Related Side Effects and Adverse Reactions; F

2017

Other Studies

18 other studies available for niacinamide and HIV Coinfection

ArticleYear
Spectroscopic studies on noncovalent binding of nicotinamide-modified BRCA1 (856-871) analogs to calf thymus DNA.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2023, Jun-05, Volume: 294

    Topics: BRCA1 Protein; Circular Dichroism; HIV Infections; Humans; Molecular Docking Simulation; Niacinamide

2023
Evidence of Noncompetent HIV after Ex Vivo Purging Among ART-Suppressed Individuals.
    AIDS research and human retroviruses, 2017, Volume: 33, Issue:10

    Topics: Anti-HIV Agents; Enzyme Inhibitors; HIV; HIV Infections; Humans; Methyltransferases; Microscopy, Ele

2017
Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Anti-HIV Agents; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Do

2018
Letter: Sorafenib hepatotoxicity may be enhanced during treatment of advanced hepatocellular carcinoma in HIV-infected patients.
    Alimentary pharmacology & therapeutics, 2013, Volume: 38, Issue:11-12

    Topics: Adult; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Carcinoma, Hepatocellular; Chem

2013
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HI

2014
The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.
    BMC infectious diseases, 2015, Aug-19, Volume: 15

    Topics: Acquired Immunodeficiency Syndrome; Adult; Africa South of the Sahara; Antiretroviral Therapy, Highl

2015
Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Anti-HIV Agents; Aspergillus niger; Cell Line; Drug Screening Assays, Antitumor; HIV Infections; HIV

2016
Sorafenib therapy for hepatocellular carcinoma in an HIV-HCV coinfected patient: a case report.
    The oncologist, 2010, Volume: 15, Issue:2

    Topics: Adult; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Comorbidity; Hepatitis C

2010
Complete response after sorafenib therapy for hepatocellular carcinoma in an HIV-HBV co infected patient: Possible synergy with HAART ? A case report.
    Medical oncology (Northwood, London, England), 2011, Volume: 28 Suppl 1

    Topics: Aged; Antiretroviral Therapy, Highly Active; Benzenesulfonates; Carcinoma, Hepatocellular; Coinfecti

2011
[Clinical characteristics, staging and treatment of patients with hepatocellular carcinoma in clinical practice. Prospective study of 136 patients].
    Gastroenterologia y hepatologia, 2011, Volume: 34, Issue:8

    Topics: Aged; Alcoholism; Benzenesulfonates; Carcinoma, Hepatocellular; Comorbidity; Diabetes Mellitus; Earl

2011
Sorafenib for the treatment of unresectable hepatocellular carcinoma in HIV-positive patients.
    Anti-cancer drugs, 2013, Volume: 24, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Carcinoma, Hepatocellular

2013
Niacin nutritional status in HIV type 1-positive children: preliminary data.
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 44, Issue:5

    Topics: Cross-Sectional Studies; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; N

2007
Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro.
    Retrovirology, 2008, Mar-31, Volume: 5

    Topics: Benzylamines; CCR5 Receptor Antagonists; CD4-Positive T-Lymphocytes; Cell Communication; Cell Line;

2008
HIV infection decreases intracellular nicotinamide adenine dinucleotide [NAD].
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Cell Line; Cells, Cultured; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Lymphocytes; NAD;

1995
Nicotinamide inhibits HIV-1 in both acute and chronic in vitro infection.
    Biochemical and biophysical research communications, 1995, May-25, Volume: 210, Issue:3

    Topics: Antiviral Agents; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; HIV I

1995
Mitochondria alterations and dramatic tendency to undergo apoptosis in peripheral blood lymphocytes during acute HIV syndrome.
    AIDS (London, England), 1997, Volume: 11, Issue:1

    Topics: Acetylcarnitine; Acetylcysteine; Acute Disease; Adult; Antioxidants; Apoptosis; CD4 Lymphocyte Count

1997
Apoptotic DNA fragmentation, and its in vitro prevention by nicotinamide, in lymphocytes from HIV-1-seropositive patients and in HIV-1-infected MT-4 cells.
    Cell biochemistry and function, 1997, Volume: 15, Issue:3

    Topics: Adult; Apoptosis; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Fragmentation; Female; Flow Cytom

1997
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jan-08, Volume: 99, Issue:1

    Topics: Amino Acid Sequence; Antibodies, Monoclonal; CCR5 Receptor Antagonists; Cells, Cultured; Chemokine C

2002