niacinamide has been researched along with Graves Disease in 10 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iodine-induced hyperthyroidism has been frequently described when iodine is introduced into an iodine-deficient area." | 7.67 | Five patients with iodine-induced hyperthyroidism. ( Braverman, LE; Mordes, JP; Rajatanavin, R; Safran, M; Stoller, WA, 1984) |
| " We describe a case with progressive recurrent chordoma who initially became hyperthyroid in a context of autoimmunity under sorafenib treatment and later under imatinib treatment." | 3.83 | Auto-immune thyroid dysfunction induced by tyrosine kinase inhibitors in a patient with recurrent chordoma. ( Castinetti, F; Eroukhmanoff, J; Penel, N; Salas, S, 2016) |
| "Iodine-induced hyperthyroidism has been frequently described when iodine is introduced into an iodine-deficient area." | 3.67 | Five patients with iodine-induced hyperthyroidism. ( Braverman, LE; Mordes, JP; Rajatanavin, R; Safran, M; Stoller, WA, 1984) |
| " Preincubation with the antithyroid drug methimazole, at concentrations ranging from 0-25 microM, prevented superoxide-induced fibroblast proliferation in a dose-response pattern." | 1.30 | Superoxide radical production stimulates retroocular fibroblast proliferation in Graves' ophthalmopathy. ( Bahn, RS; Barnes, S; Burch, HB; Lahiri, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eroukhmanoff, J | 1 |
| Castinetti, F | 1 |
| Penel, N | 1 |
| Salas, S | 1 |
| Bartalena, L | 1 |
| Tanda, ML | 1 |
| Piantanida, E | 1 |
| Lai, A | 1 |
| Rajatanavin, R | 1 |
| Safran, M | 1 |
| Stoller, WA | 1 |
| Mordes, JP | 1 |
| Braverman, LE | 1 |
| Filetti, S | 1 |
| Takai, NA | 1 |
| Rapoport, B | 1 |
| Hiromatsu, Y | 3 |
| Sato, M | 3 |
| Tanaka, K | 1 |
| Ishisaka, N | 1 |
| Kamachi, J | 1 |
| Nonaka, K | 3 |
| Burch, HB | 1 |
| Lahiri, S | 1 |
| Bahn, RS | 2 |
| Barnes, S | 1 |
| Yang, D | 1 |
| Miyake, I | 1 |
| Koga, M | 1 |
| Kameo, J | 1 |
| Inoue, Y | 1 |
| Bouzas, EA | 1 |
| Karadimas, P | 1 |
| Mastorakos, G | 1 |
| Koutras, DA | 1 |
| Heufelder, AE | 1 |
| Wenzel, BE | 1 |
| Yamada, K | 1 |
1 review available for niacinamide and Graves Disease
| Article | Year |
|---|---|
Oxidative stress and Graves' ophthalmopathy: in vitro studies and therapeutic implications.
Topics: Dose-Response Relationship, Drug; Eye Diseases; Fibroblasts; Free Radical Scavengers; Graves Disease | 2003 |
1 trial available for niacinamide and Graves Disease
| Article | Year |
|---|---|
Antioxidant agents in the treatment of Graves' ophthalmopathy.
Topics: Administration, Oral; Adult; Allopurinol; Antioxidants; Drug Evaluation; Female; Graves Disease; Hum | 2000 |
8 other studies available for niacinamide and Graves Disease
| Article | Year |
|---|---|
Auto-immune thyroid dysfunction induced by tyrosine kinase inhibitors in a patient with recurrent chordoma.
Topics: Antineoplastic Agents; Chordoma; Graves Disease; Humans; Imatinib Mesylate; Male; Middle Aged; Neopl | 2016 |
Five patients with iodine-induced hyperthyroidism.
Topics: Adult; Amiodarone; Chlorobutanol; Coloring Agents; Coronary Artery Bypass; Drug Combinations; Female | 1984 |
Prevention by nicotinamide of desensitization to thyrotropin stimulation in cultured human thyroid cells.
Topics: Cells, Cultured; Cyclic AMP; Cycloheximide; Drug Synergism; Graves Disease; Humans; Kinetics; Niacin | 1981 |
Inhibitory effects of nicotinamide on intercellular adhesion molecule-1 expression on cultured human thyroid cells.
Topics: Antigens, CD; Cell Adhesion Molecules; Cells, Cultured; Dose-Response Relationship, Immunologic; Gra | 1993 |
Superoxide radical production stimulates retroocular fibroblast proliferation in Graves' ophthalmopathy.
Topics: Allopurinol; Analysis of Variance; Antioxidants; Antithyroid Agents; Cell Division; Connective Tissu | 1997 |
Nicotinamide decreases cytokine-induced activation of orbital fibroblasts from patients with thyroid-associated ophthalmopathy.
Topics: Adipose Tissue; Cell Division; Cells, Cultured; Cytokines; fas Receptor; Fibroblasts; Graves Disease | 1998 |
Methimazole and propylthiouracil inhibit the oxygen free radical-induced expression of a 72 kilodalton heat shock protein in Graves' retroocular fibroblasts.
Topics: 3,3'-Diaminobenzidine; Cells, Cultured; Connective Tissue; Electrophoresis, Polyacrylamide Gel; Eye; | 1992 |
Nicotinamide and 3-aminobenzamide inhibit recombinant human interferon-gamma-induced HLA-DR antigen expression, but not HLA-A, B, C antigen expression, on cultured human thyroid cells.
Topics: Benzamides; Cells, Cultured; Flow Cytometry; Graves Disease; HLA-A Antigens; HLA-B Antigens; HLA-C A | 1992 |