niacinamide has been researched along with Genetic Predisposition in 17 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sorafenib currently sets the new standard for advanced hepatocellular carcinoma (HCC)." | 7.79 | Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma. ( Bae, SH; Chung, YH; Kim, BI; Kim, JA; Koh, KC; Lee, D; Lee, HC; Lee, JH; Park, NH; Shim, JH; Shin, ES; Yoon, JH, 2013) |
| "Sorafenib is a small molecular inhibitor of intracellular tyrosine and serine/threonine protein kinases (VEGFR, PDGFR, CRAF and BRAF), and is thought also to induce autophagy, a chief mechanism influencing tumor growth." | 6.53 | Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib. ( Grieco, A; Mazzoccoli, G; Miele, L; Oben, J; Vinciguerra, M, 2016) |
| "Sorafenib currently sets the new standard for advanced hepatocellular carcinoma (HCC)." | 3.79 | Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma. ( Bae, SH; Chung, YH; Kim, BI; Kim, JA; Koh, KC; Lee, D; Lee, HC; Lee, JH; Park, NH; Shim, JH; Shin, ES; Yoon, JH, 2013) |
| "First degree relatives of type 1 diabetes children attending paediatric clinics in Norway were recruited." | 2.69 | [Genetic and immunologic risks for development of type 1 diabetes--experiences from an intervention trial]. ( Dahl-Jørgensen, K; Joner, G; Nicol-Smith, L; Rønningen, KS; Søvik, O; Torjesen, PA; Undlien, DE, 2000) |
| "Sorafenib is a small molecular inhibitor of intracellular tyrosine and serine/threonine protein kinases (VEGFR, PDGFR, CRAF and BRAF), and is thought also to induce autophagy, a chief mechanism influencing tumor growth." | 2.53 | Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib. ( Grieco, A; Mazzoccoli, G; Miele, L; Oben, J; Vinciguerra, M, 2016) |
| "This increase may be part genetic predisposition, and part induction, by excessive exposure to its substrates (particularly nicotinamide) or stress." | 2.43 | Parkinson's disease: the first common neurological disease due to auto-intoxication? ( Cartwright, LS; Ramsden, DB; Williams, AC, 2005) |
| " Pharmacokinetic analysis revealed that oral dosing of t-CUPM resulted in higher blood levels than that of sorafenib throughout the complete time course (48 h)." | 1.43 | Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. ( Hammock, BD; Hwang, SH; Li, H; Liao, J; Liu, JY; Wecksler, AT; Yang, GY; Yang, J; Yang, Y, 2016) |
| "Thirty-six patients with advanced cancer underwent molecular profiling with NGS with the intent of clinical application of available matched targeted agents." | 1.43 | Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy in Refractory Solid Tumors at a Korean Institution. ( Kim, HR; Kim, JH; Kim, S; Kwack, K; Lee, MG; Lim, SM; Moon, YW; Park, HS, 2016) |
| "Malnutrition affects up to one billion people in the world and is a major cause of mortality." | 1.38 | ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. ( Camargo, SM; Clevers, H; Fukamizu, A; Hanada, R; Hanada, T; Hashimoto, T; Ishiguro, H; Kuba, K; Lipinski, S; Paolino, M; Penninger, JM; Perlot, T; Rehman, A; Richter, A; Rosenstiel, P; Schreiber, S; Sigl, V; Singer, D; Trichereau, J; Verrey, F; Wild, B, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sambeat, A | 1 |
| Ratajczak, J | 1 |
| Joffraud, M | 1 |
| Sanchez-Garcia, JL | 1 |
| Giner, MP | 1 |
| Valsesia, A | 1 |
| Giroud-Gerbetant, J | 1 |
| Valera-Alberni, M | 1 |
| Cercillieux, A | 1 |
| Boutant, M | 1 |
| Kulkarni, SS | 1 |
| Moco, S | 1 |
| Canto, C | 1 |
| Simmons, K | 1 |
| Michels, AW | 1 |
| Mazzoccoli, G | 1 |
| Miele, L | 1 |
| Oben, J | 1 |
| Grieco, A | 1 |
| Vinciguerra, M | 1 |
| Liao, J | 2 |
| Hwang, SH | 2 |
| Li, H | 2 |
| Yang, Y | 1 |
| Yang, J | 1 |
| Wecksler, AT | 1 |
| Liu, JY | 2 |
| Hammock, BD | 2 |
| Yang, GY | 2 |
| Park, HS | 1 |
| Lim, SM | 1 |
| Kim, S | 2 |
| Kim, HR | 1 |
| Kwack, K | 1 |
| Lee, MG | 1 |
| Kim, JH | 1 |
| Moon, YW | 1 |
| Huang, A | 1 |
| Ju, HQ | 1 |
| Liu, K | 1 |
| Zhan, G | 1 |
| Liu, D | 1 |
| Wen, S | 1 |
| Garcia-Manero, G | 1 |
| Huang, P | 1 |
| Hu, Y | 1 |
| Villanueva, A | 1 |
| Newell, P | 1 |
| Hoshida, Y | 1 |
| Caronia, LM | 1 |
| Phay, JE | 1 |
| Shah, MH | 1 |
| Guo, JM | 1 |
| Dong, WZ | 1 |
| Liu, AJ | 1 |
| Cheng, MH | 1 |
| Su, DF | 1 |
| Lee, JH | 1 |
| Chung, YH | 1 |
| Kim, JA | 1 |
| Shim, JH | 1 |
| Lee, D | 1 |
| Lee, HC | 1 |
| Shin, ES | 1 |
| Yoon, JH | 1 |
| Kim, BI | 1 |
| Bae, SH | 1 |
| Koh, KC | 1 |
| Park, NH | 1 |
| Hashimoto, T | 1 |
| Perlot, T | 1 |
| Rehman, A | 1 |
| Trichereau, J | 1 |
| Ishiguro, H | 1 |
| Paolino, M | 1 |
| Sigl, V | 1 |
| Hanada, T | 1 |
| Hanada, R | 1 |
| Lipinski, S | 1 |
| Wild, B | 1 |
| Camargo, SM | 1 |
| Singer, D | 1 |
| Richter, A | 1 |
| Kuba, K | 1 |
| Fukamizu, A | 1 |
| Schreiber, S | 1 |
| Clevers, H | 1 |
| Verrey, F | 1 |
| Rosenstiel, P | 1 |
| Penninger, JM | 1 |
| Williams, AC | 1 |
| Cartwright, LS | 1 |
| Ramsden, DB | 1 |
| Cabrera-Rode, E | 1 |
| Molina, G | 1 |
| Arranz, C | 1 |
| Vera, M | 1 |
| González, P | 1 |
| Suárez, R | 1 |
| Prieto, M | 1 |
| Padrón, S | 1 |
| León, R | 1 |
| Tillan, J | 1 |
| García, I | 1 |
| Tiberti, C | 1 |
| Rodríguez, OM | 1 |
| Gutiérrez, A | 1 |
| Fernández, T | 1 |
| Govea, A | 1 |
| Hernández, J | 1 |
| Chiong, D | 1 |
| Domínguez, E | 1 |
| Di Mario, U | 1 |
| Díaz-Díaz, O | 1 |
| Díaz-Horta, O | 1 |
| Yan, Z | 1 |
| Wu, Y | 2 |
| van Driel, LM | 1 |
| Smedts, HP | 1 |
| Helbing, WA | 1 |
| Isaacs, A | 1 |
| Lindemans, J | 1 |
| Uitterlinden, AG | 1 |
| van Duijn, CM | 1 |
| de Vries, JH | 1 |
| Steegers, EA | 1 |
| Steegers-Theunissen, RP | 1 |
| Undlien, DE | 1 |
| Joner, G | 1 |
| Dahl-Jørgensen, K | 1 |
| Rønningen, KS | 1 |
| Nicol-Smith, L | 1 |
| Torjesen, PA | 1 |
| Søvik, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of a Synbiotic Formula in Patient With COVID-19[NCT04730284] | 20 participants (Anticipated) | Interventional | 2020-08-25 | Recruiting | |||
| An Evaluation of a Synbiotic Formula for Symptom Improvement in Hospitalised Patients With COVID-19 Infection[NCT04581018] | 50 participants (Anticipated) | Interventional | 2020-08-13 | Enrolling by invitation | |||
| Investigating the Inflammatory Cytokines and Cytokine Storm Among Bangladeshi Patients With COVID-19: a Prospective, Observational Study[NCT04598334] | 75 participants (Anticipated) | Observational | 2022-07-15 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for niacinamide and Genetic Predisposition
| Article | Year |
|---|---|
Lessons from type 1 diabetes for understanding natural history and prevention of autoimmune disease.
Topics: Abatacept; Antibodies, Monoclonal, Humanized; Autoantibodies; Autoimmune Diseases; Diabetes Mellitus | 2014 |
Biology, Epidemiology, Clinical Aspects of Hepatocellular Carcinoma and the Role of Sorafenib.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Clinical Trials as Topic; Female; Genetic Predisposit | 2016 |
Inherited hepatocellular carcinoma.
Topics: Algorithms; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Catheter Ablation; | 2010 |
Role of BRAF in thyroid oncogenesis.
Topics: Benzenesulfonates; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; Humans; Mutat | 2011 |
Parkinson's disease: the first common neurological disease due to auto-intoxication?
Topics: Brain; Environment; Genetic Predisposition to Disease; Humans; Inactivation, Metabolic; Methyltransf | 2005 |
[Relation between cytochrome P450 2D6 and lung cancer susceptibility caused by smoking].
Topics: Cytochrome P-450 CYP2D6; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Niacinamide; Nit | 2007 |
2 trials available for niacinamide and Genetic Predisposition
| Article | Year |
|---|---|
Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.
Topics: Adolescent; Adult; Autoantibodies; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus, Type 1 | 2006 |
[Genetic and immunologic risks for development of type 1 diabetes--experiences from an intervention trial].
Topics: Adult; Child; Diabetes Mellitus, Type 1; Double-Blind Method; Genetic Markers; Genetic Predispositio | 2000 |
9 other studies available for niacinamide and Genetic Predisposition
| Article | Year |
|---|---|
Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage.
Topics: Animals; Blood Glucose; Diet, High-Fat; Disease Models, Animal; DNA Damage; Gene Knockout Techniques | 2019 |
Inhibition of mutant KrasG12D-initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzoates; Carcinoma, Pancreatic Ductal; Cell | 2016 |
Inhibition of Chronic Pancreatitis and Murine Pancreatic Intraepithelial Neoplasia by a Dual Inhibitor of c-RAF and Soluble Epoxide Hydrolase in LSL-KrasG¹²D/Pdx-1-Cre Mice.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Carcinoma in Situ; Ceruletide; Chromatog | 2016 |
Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy in Refractory Solid Tumors at a Korean Institution.
Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Asian People; Class I Phosphatidylinositol 3-Kinases; | 2016 |
Metabolic alterations and drug sensitivity of tyrosine kinase inhibitor resistant leukemia cells with a FLT3/ITD mutation.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Dos | 2016 |
Nicotinamide postpones stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Genetic Predisposition to Disease; Male; Membrane Potential, Mitochondrial; Niacinamide; Ra | 2012 |
Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Female; Genetic Pr | 2013 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary | 2012 |
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
Topics: Adult; Child; Drug-Related Side Effects and Adverse Reactions; Epidemiologic Methods; Female; Geneti | 2008 |