niacinamide has been researched along with Gelineau Syndrome in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These agents can increase wakefulness (W) in cats and rodents following acute administration, but their effects after repeat dosing have not been reported previously." | 1.35 | Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice. ( Anaclet, C; Brown, SH; Buda, C; Feng, JQ; Franco, P; Guidon, G; Guo, RX; Lin, JS; Medhurst, AD; Parmentier, R; Roberts, JC; Sastre, JP; Upton, N; Zhang, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimura, Y | 1 |
| Takahata, K | 1 |
| Shimazaki, T | 1 |
| Kitamura, S | 1 |
| Seki, C | 1 |
| Ikoma, Y | 1 |
| Ichise, M | 1 |
| Kawamura, K | 1 |
| Yamada, M | 1 |
| Zhang, MR | 1 |
| Higuchi, M | 1 |
| Nishino, I | 1 |
| Suhara, T | 1 |
| Guo, RX | 1 |
| Anaclet, C | 1 |
| Roberts, JC | 1 |
| Parmentier, R | 1 |
| Zhang, M | 1 |
| Guidon, G | 1 |
| Buda, C | 1 |
| Sastre, JP | 1 |
| Feng, JQ | 1 |
| Franco, P | 1 |
| Brown, SH | 1 |
| Upton, N | 1 |
| Medhurst, AD | 1 |
| Lin, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study on Histamine H3 Receptor Occupancy of TS-091 by PET Examination in Healthy Adult Subjects[NCT04631276] | Phase 1 | 12 participants (Actual) | Interventional | 2014-12-11 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for niacinamide and Gelineau Syndrome
| Article | Year |
|---|---|
Pharmacokinetic and pharmacodynamic assessment of histamine H
Topics: Brain; Histamine; Humans; Ligands; Male; Narcolepsy; Neuroprotective Agents; Niacinamide; Positron-E | 2022 |
Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice.
Topics: Animals; Autoradiography; Benzazepines; Benzhydryl Compounds; Brain; Dose-Response Relationship, Dru | 2009 |