Page last updated: 2024-10-19

niacinamide and Gallbladder Neoplasms

niacinamide has been researched along with Gallbladder Neoplasms in 7 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Gallbladder Neoplasms: Tumors or cancer of the gallbladder.

Research Excerpts

ExcerptRelevanceReference
"Since sorafenib has shown activity in different tumour types and gemcitabine regimens improved the outcome for biliary tract cancer (BTC) patients, we evaluated first-line gemcitabine plus sorafenib in a double-blind phase II study."9.19Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme. ( Berie, L; Denzer, U; Distelrath, A; Dollinger, MM; Duerr, EM; Ebert, MP; Galle, PR; Geissler, M; Kaiser, AK; Kanzler, S; Kolligs, FT; Lammert, F; Lindig, U; Lohse, A; Lubomierski, N; Maderer, A; Moehler, M; Sauvigny, C; Schadmand-Fischer, S; Schimanski, C; Schütz, M; Trojan, J; Wachtlin, D; Woerns, M; Zimmermann, S, 2014)
"This study evaluated the addition of sorafenib to gemcitabine and cisplatin in biliary adenocarcinoma first-line therapy."9.17A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas. ( Abou-Alfa, GK; Capanu, M; Chou, JF; Chung, KY; Gansukh, B; Katz, SS; Lee, JK; Ma, J; O'Reilly, EM; Reidy-Lagunes, D; Saltz, LB; Segal, NH; Shia, J; Yu, KH, 2013)
"We conducted a phase II trial of single-agent sorafenib in patients with advanced biliary tract carcinoma."9.14Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. ( Aitini, E; Bengala, C; Bertolini, F; Boni, C; Conte, P; Dealis, C; Del Giovane, C; Depenni, R; Fontana, A; Luppi, G; Malavasi, N; Zironi, S, 2010)
"Sorafenib and erlotinib were administered continuously at 400 mg BID and 100 mg daily, respectively."6.79S0941: a phase 2 SWOG study of sorafenib and erlotinib in patients with advanced gallbladder carcinoma or cholangiocarcinoma. ( Blanke, CD; El-Khoueiry, AB; Gong, IY; Iqbal, S; Kayaleh, OR; Lenz, HJ; Micetich, KC; Rankin, C; Siegel, AB, 2014)
"Sorafenib was administered at 400 mg po twice daily continuously."6.77SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma. ( Ben-Josef, E; Blanke, CD; El-Khoueiry, AB; Eng, C; Gold, PJ; Govindarajan, R; Hamilton, RD; Lenz, HJ; Rankin, CJ, 2012)
"Since sorafenib has shown activity in different tumour types and gemcitabine regimens improved the outcome for biliary tract cancer (BTC) patients, we evaluated first-line gemcitabine plus sorafenib in a double-blind phase II study."5.19Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme. ( Berie, L; Denzer, U; Distelrath, A; Dollinger, MM; Duerr, EM; Ebert, MP; Galle, PR; Geissler, M; Kaiser, AK; Kanzler, S; Kolligs, FT; Lammert, F; Lindig, U; Lohse, A; Lubomierski, N; Maderer, A; Moehler, M; Sauvigny, C; Schadmand-Fischer, S; Schimanski, C; Schütz, M; Trojan, J; Wachtlin, D; Woerns, M; Zimmermann, S, 2014)
"This study evaluated the addition of sorafenib to gemcitabine and cisplatin in biliary adenocarcinoma first-line therapy."5.17A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas. ( Abou-Alfa, GK; Capanu, M; Chou, JF; Chung, KY; Gansukh, B; Katz, SS; Lee, JK; Ma, J; O'Reilly, EM; Reidy-Lagunes, D; Saltz, LB; Segal, NH; Shia, J; Yu, KH, 2013)
"We conducted a phase II trial of single-agent sorafenib in patients with advanced biliary tract carcinoma."5.14Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. ( Aitini, E; Bengala, C; Bertolini, F; Boni, C; Conte, P; Dealis, C; Del Giovane, C; Depenni, R; Fontana, A; Luppi, G; Malavasi, N; Zironi, S, 2010)
"Sorafenib and erlotinib were administered continuously at 400 mg BID and 100 mg daily, respectively."2.79S0941: a phase 2 SWOG study of sorafenib and erlotinib in patients with advanced gallbladder carcinoma or cholangiocarcinoma. ( Blanke, CD; El-Khoueiry, AB; Gong, IY; Iqbal, S; Kayaleh, OR; Lenz, HJ; Micetich, KC; Rankin, C; Siegel, AB, 2014)
"Sorafenib was administered at 400 mg po twice daily continuously."2.77SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma. ( Ben-Josef, E; Blanke, CD; El-Khoueiry, AB; Eng, C; Gold, PJ; Govindarajan, R; Hamilton, RD; Lenz, HJ; Rankin, CJ, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Li, Y1
Yang, B1
Miao, H1
Liu, L1
Wang, Z1
Jiang, C1
Yang, Y1
Qiu, S1
Li, X1
Geng, Y1
Zhang, Y1
Liu, Y1
Lee, JK1
Capanu, M1
O'Reilly, EM1
Ma, J1
Chou, JF1
Shia, J1
Katz, SS1
Gansukh, B1
Reidy-Lagunes, D1
Segal, NH1
Yu, KH1
Chung, KY1
Saltz, LB1
Abou-Alfa, GK1
El-Khoueiry, AB2
Rankin, C1
Siegel, AB1
Iqbal, S1
Gong, IY1
Micetich, KC1
Kayaleh, OR1
Lenz, HJ2
Blanke, CD2
Moehler, M1
Maderer, A1
Schimanski, C1
Kanzler, S1
Denzer, U1
Kolligs, FT1
Ebert, MP1
Distelrath, A1
Geissler, M1
Trojan, J1
Schütz, M1
Berie, L1
Sauvigny, C1
Lammert, F1
Lohse, A1
Dollinger, MM1
Lindig, U1
Duerr, EM1
Lubomierski, N1
Zimmermann, S1
Wachtlin, D1
Kaiser, AK1
Schadmand-Fischer, S1
Galle, PR1
Woerns, M1
Bengala, C1
Bertolini, F1
Malavasi, N1
Boni, C1
Aitini, E1
Dealis, C1
Zironi, S1
Depenni, R1
Fontana, A1
Del Giovane, C1
Luppi, G1
Conte, P1
Rankin, CJ1
Ben-Josef, E1
Gold, PJ1
Hamilton, RD1
Govindarajan, R1
Eng, C1
Faris, JE1
Zhu, AX1

Reviews

1 review available for niacinamide and Gallbladder Neoplasms

ArticleYear
Targeted therapy for biliary tract cancers.
    Journal of hepato-biliary-pancreatic sciences, 2012, Volume: 19, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A

2012

Trials

5 trials available for niacinamide and Gallbladder Neoplasms

ArticleYear
A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas.
    British journal of cancer, 2013, Aug-20, Volume: 109, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile

2013
S0941: a phase 2 SWOG study of sorafenib and erlotinib in patients with advanced gallbladder carcinoma or cholangiocarcinoma.
    British journal of cancer, 2014, Feb-18, Volume: 110, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile D

2014
Gemcitabine plus sorafenib versus gemcitabine alone in advanced biliary tract cancer: a double-blind placebo-controlled multicentre phase II AIO study with biomarker and serum programme.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms;

2014
Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial.
    British journal of cancer, 2010, Jan-05, Volume: 102, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Bile Duct Neoplasms; Bilia

2010
SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma.
    Investigational new drugs, 2012, Volume: 30, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Cholangiocarcinoma; Diseas

2012

Other Studies

1 other study available for niacinamide and Gallbladder Neoplasms

ArticleYear
Nicotinamide N -methyltransferase promotes M2 macrophage polarization by IL6 and MDSC conversion by GM-CSF in gallbladder carcinoma.
    Hepatology (Baltimore, Md.), 2023, 11-01, Volume: 78, Issue:5

    Topics: Gallbladder Neoplasms; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Leuk

2023