Page last updated: 2024-10-19

niacinamide and Fibrosarcoma

niacinamide has been researched along with Fibrosarcoma in 8 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" Sorafenib is a multi-kinase inhibitor that targets rapidly accelerated fibrosarcoma (RAF), vascular endothelial growth factor receptor (VEGFR)-1, VEGFR-2, VEGFR-3, platelet-derived growth factor receptor-β (PDGFR-β), and KIT."4.12Sorafenib inhibits tumor cell growth and angiogenesis in canine transitional cell carcinoma. ( Maeda, S; Momoi, Y; Yokota, S; Yonezawa, T, 2022)
"We hypothesized that the combination of pentoxifylline (PTX) and nicotinamide (NA) can reduce the radioresistance of FSaII murine fibrosarcoma by improving oxygenation of the hypoxic tumour cells."3.68Improved tumour oxygenation and radiosensitization by combination with nicotinamide and pentoxifylline. ( Lee, I; Levitt, SH; Song, CW, 1993)
" Fluorine-19 NMR spectroscopic measurements from solid Radiation-Induced Fibrosarcoma (RIF-1) tumors in C3H mice showed a statistically significant improvement in tumor pO2 for a Nicotinamide-treated group, with a delta pO2 = 4."3.68Assessment of changes in murine tumor oxygenation in response to nicotinamide using 19F NMR relaxometry of a perfluorocarbon emulsion. ( Hees, PS; Sotak, CH, 1993)
" The purpose of this study was to examine the effects of PENTO alone or in combination with NA (PENTO + NA) on the oxygenation and radio-response of FSaII murine fibrosarcomas of mice."1.28Increases in tumor response by pentoxifylline alone or in combination with nicotinamide. ( Kim, JH; Lee, I; Levitt, SH; Song, CW, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Yokota, S1
Yonezawa, T1
Momoi, Y1
Maeda, S1
Karroum, O1
Kengen, J1
Danhier, P1
Magat, J1
Mignion, L1
Bouzin, C1
Verrax, J1
Charette, N1
Starkel, P1
Calderon, PB1
Sonveaux, P1
Feron, O1
Grégoire, V1
Gallez, B2
Jordan, BF2
Baudelet, C1
Ansiaux, R1
Havaux, X1
Macq, B1
Price, MJ1
Li, LT1
Tward, JD1
Bublik, I1
McBride, WH1
Lavey, RS1
Lee, I2
Levitt, SH2
Song, CW2
Hees, PS1
Sotak, CH1
Fenton, BM1
Lord, EM1
Paoni, SF1
Kim, JH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Tumor Oximetry Using Electron Paramagnetic Resonance (EPR) With India Ink (Using Carbon Particulates From Carlo Erba [CE])[NCT03321903]3 participants (Actual)Observational2017-08-30Terminated (stopped due to The research team is exploring device optimization)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for niacinamide and Fibrosarcoma

ArticleYear
Sorafenib inhibits tumor cell growth and angiogenesis in canine transitional cell carcinoma.
    The Journal of veterinary medical science, 2022, May-17, Volume: 84, Issue:5

    Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Line, Tumor; Dog Diseases; Dogs;

2022
Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1

    Topics: Angiogenesis Inducing Agents; Animals; Apoptosis; Benzamides; Blotting, Western; Diphenylamine; Elec

2012
Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?
    Physics in medicine and biology, 2004, Aug-07, Volume: 49, Issue:15

    Topics: Animals; Biomarkers, Tumor; Carbon Dioxide; Cell Hypoxia; Cell Line, Tumor; Computer Simulation; Fib

2004
Effect of nicotinamide and pentoxifylline on normal tissue and FSA tumor oxygenation.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Analysis of Variance; Animals; Drug Interactions; Fibrosarcoma; Male; Mice; Mice, Inbred C3H; Muscle

1995
Improved tumour oxygenation and radiosensitization by combination with nicotinamide and pentoxifylline.
    International journal of radiation biology, 1993, Volume: 64, Issue:2

    Topics: Animals; Drug Combinations; Fibrosarcoma; Laser-Doppler Flowmetry; Mice; Microelectrodes; Niacinamid

1993
Assessment of changes in murine tumor oxygenation in response to nicotinamide using 19F NMR relaxometry of a perfluorocarbon emulsion.
    Magnetic resonance in medicine, 1993, Volume: 29, Issue:3

    Topics: Animals; Body Temperature; Calibration; Emulsions; Fibrosarcoma; Fluorine; Fluorocarbons; Magnetic R

1993
Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: Animals; Carbocyanines; Carbon Dioxide; Cell Hypoxia; Combined Modality Therapy; Dose Fractionation,

2000
Increases in tumor response by pentoxifylline alone or in combination with nicotinamide.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Animals; Cell Hypoxia; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Therap

1992