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niacinamide and Fatty Liver

niacinamide has been researched along with Fatty Liver in 18 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" In addition, increased hepatic microvasculatures compliance-related improved buffering effect of portal vein to acute mannitol infusion was associated with decreased circulating nitric oxide and aldosterone, plasma volume expansion (dye dilution method), splanchnic blood pooling ((99 m) Tc-RBC SPECT/PET/CT scans), peripheral hypotension, portal hypertension and ascites in brivanib and sorafenib-treated NASH-cirrhotic rats."3.80Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat. ( Hsieh, YC; Huang, YT; Lee, FY; Lee, KC; Lee, PC; Lee, WP; Lin, HC; Liu, RS; Tan, TW; Yang, YY; Yeh, YC, 2014)
"Deletion of glycine N-methyltransferase (GNMT), the main gene involved in liver S-adenosylmethionine (SAM) catabolism, leads to the hepatic accumulation of this molecule and the development of fatty liver and fibrosis in mice."3.76Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide. ( Calvisi, DF; Embade, N; Esteller, M; Fernández-Ramos, D; Frades, I; Fraga, MF; Julve, J; Lu, SC; Luka, Z; Martínez-Chantar, ML; Martínez-López, N; Mato, JM; Rodríguez, J; Rodríguez-Millán, E; Torres, L; Varela-Rey, M; Wagner, C; Woodhoo, A, 2010)
"In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes."1.40Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. ( Alhonen, L; Asara, JM; Banks, AS; Bhanot, S; Cen, Y; Gong, F; Kahn, BB; Kong, D; Kraus, D; Monia, BP; Peroni, OD; Pirinen, E; Puigserver, P; Pulinilkunnil, TC; Rodgers, JT; Sauve, AA; Wang, YC; Yang, Q; Zhang, L, 2014)
"Sorafenib was acutely administered to NASH rats with IR liver injury that were or were not chronically pretreated with the Rho-kinase-specific inhibitor fasudil."1.38Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis. ( Chan, CC; Huang, YT; Lee, KC; Lee, TY; Lin, HC; Yang, YY; Yeh, YC, 2012)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (61.11)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Song, Q1
Wang, J1
Griffiths, A1
Lee, SM1
Iyamu, ID1
Huang, R1
Cordoba-Chacon, J1
Song, Z1
Diani-Moore, S1
Shoots, J1
Singh, R1
Zuk, JB1
Rifkind, AB1
Mitchell, SJ1
Bernier, M1
Aon, MA1
Cortassa, S1
Kim, EY1
Fang, EF1
Palacios, HH1
Ali, A1
Navas-Enamorado, I1
Di Francesco, A1
Kaiser, TA1
Waltz, TB1
Zhang, N1
Ellis, JL1
Elliott, PJ1
Frederick, DW1
Bohr, VA1
Schmidt, MS1
Brenner, C1
Sinclair, DA1
Sauve, AA3
Baur, JA1
de Cabo, R1
Fan, R1
Cui, J1
Ren, F1
Wang, Q1
Huang, Y1
Zhao, B1
Wei, L1
Qian, X1
Xiong, X1
Komatsu, M1
Kanda, T1
Urai, H1
Kurokochi, A1
Kitahama, R1
Shigaki, S1
Ono, T1
Yukioka, H1
Hasegawa, K1
Tokuyama, H1
Kawabe, H1
Wakino, S1
Itoh, H1
Yang, YY2
Liu, RS1
Lee, PC1
Yeh, YC2
Huang, YT2
Lee, WP1
Lee, KC2
Hsieh, YC1
Lee, FY1
Tan, TW1
Lin, HC2
Kraus, D1
Yang, Q1
Kong, D1
Banks, AS1
Zhang, L1
Rodgers, JT1
Pirinen, E1
Pulinilkunnil, TC1
Gong, F1
Wang, YC1
Cen, Y1
Asara, JM1
Peroni, OD1
Monia, BP1
Bhanot, S1
Alhonen, L1
Puigserver, P1
Kahn, BB1
Gariani, K1
Menzies, KJ1
Ryu, D1
Wegner, CJ1
Wang, X1
Ropelle, ER1
Moullan, N1
Zhang, H1
Perino, A1
Lemos, V1
Kim, B1
Park, YK1
Piersigilli, A1
Pham, TX1
Yang, Y1
Ku, CS1
Koo, SI1
Fomitchova, A1
Cantó, C1
Schoonjans, K1
Lee, JY1
Auwerx, J1
Gual, P1
Postic, C1
Chao, KC1
Chen, SH1
Chang, CC1
Lee, YC1
Wang, CM1
Chang, JS1
Varela-Rey, M1
Martínez-López, N1
Fernández-Ramos, D1
Embade, N1
Calvisi, DF1
Woodhoo, A1
Rodríguez, J1
Fraga, MF1
Julve, J1
Rodríguez-Millán, E1
Frades, I1
Torres, L1
Luka, Z1
Wagner, C1
Esteller, M1
Lu, SC1
Martínez-Chantar, ML1
Mato, JM1
Lee, TY1
Chan, CC1
ESPOSITO, S1
NICROSINI, F1
PETRONIO, L1
Rikans, LL1
Arata, D1
Cederquist, DC1
Baker, H1
Frank, O1
Sorrell, MF1
Vorberg, G1
Henning, SM1
McKee, RW1
Swendseid, ME1
Marchetti, M1
Ottani, V1
Puddu, P1

Other Studies

18 other studies available for niacinamide and Fatty Liver

ArticleYear
Nicotinamide N-methyltransferase upregulation contributes to palmitate-elicited peroxisome proliferator-activated receptor transactivation in hepatocytes.
    American journal of physiology. Cell physiology, 2023, 07-01, Volume: 325, Issue:1

    Topics: Animals; Fatty Acids; Fatty Liver; Hepatocytes; Humans; Mice; NAD; Niacinamide; Nicotinamide N-Methy

2023
NAD
    Scientific reports, 2017, 05-23, Volume: 7, Issue:1

    Topics: Animals; Atrophy; Cell Line; Chick Embryo; Dioxins; Fatty Liver; NAD; Niacinamide; Poly(ADP-ribose)

2017
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.
    Cell metabolism, 2018, 03-06, Volume: 27, Issue:3

    Topics: Animals; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Healthy Aging; In

2018
Overexpression of NRK1 ameliorates diet- and age-induced hepatic steatosis and insulin resistance.
    Biochemical and biophysical research communications, 2018, 06-02, Volume: 500, Issue:2

    Topics: Aging; Animals; Diet, High-Fat; Fatty Liver; HEK293 Cells; Humans; Insulin Resistance; Lipid Metabol

2018
NNMT activation can contribute to the development of fatty liver disease by modulating the NAD
    Scientific reports, 2018, 06-05, Volume: 8, Issue:1

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Fatty Liver; Lipoproteins, VLDL; Liver

2018
Anti-VEGFR agents ameliorate hepatic venous dysregulation/microcirculatory dysfunction, splanchnic venous pooling and ascites of NASH-cirrhotic rat.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:4

    Topics: Alanine; Animals; Ascites; Cytokines; DNA Primers; Fatty Liver; Fibroblast Growth Factors; Microcirc

2014
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
    Nature, 2014, Apr-10, Volume: 508, Issue:7495

    Topics: Acetyltransferases; Adipocytes; Adipose Tissue; Adipose Tissue, White; Animals; Diabetes Mellitus, T

2014
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.
    Hepatology (Baltimore, Md.), 2016, Volume: 63, Issue:4

    Topics: Analysis of Variance; Animals; Area Under Curve; Biopsy, Needle; Diet, High-Fat; Disease Models, Ani

2016
Therapeutic potential of nicotinamide adenine dinucleotide for nonalcoholic fatty liver disease.
    Hepatology (Baltimore, Md.), 2016, Volume: 63, Issue:4

    Topics: Animals; Fatty Liver; Male; NAD; Niacinamide; Unfolded Protein Response

2016
Effects of ferric citrate supplementation on advanced glycation end products in a rat model of streptozotocin/nicotinamide-induced diabetes.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; Fat

2017
Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:1

    Topics: Animals; Fatty Liver; Gene Deletion; Gene Expression; Glycine N-Methyltransferase; Liver Cirrhosis;

2010
Rho-kinase-dependent pathway mediates the hepatoprotective effects of sorafenib against ischemia/reperfusion liver injury in rats with nonalcoholic steatohepatitis.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2012, Volume: 18, Issue:11

    Topics: Animals; Apoptosis; Disease Models, Animal; Fatty Liver; Gene Expression Regulation, Enzymologic; He

2012
[The nature and prevention of hepatic steatosis caused by massive doses of nicotinamide and 6-aminonicotinamide].
    Archivio per le scienze mediche, 1959, Volume: 108

    Topics: 6-Aminonicotinamide; Fatty Liver; Liver Diseases; Niacin; Niacinamide; Nicotinic Acids

1959
FATTY LIVERS PRODUCED IN ALBINO RATS BY EXCESS NIACIN IN HIGH FAT DIETS. II. EFFECT OF CHOLINE SUPPLEMENTS.
    The Journal of nutrition, 1965, Volume: 85

    Topics: Alkaline Phosphatase; Blood Chemical Analysis; Body Weight; Choline; Choline Deficiency; Diet Therap

1965
Nicotinic acid and alcoholism [proceedings].
    Bibliotheca nutritio et dieta, 1976, Issue:24

    Topics: Alcohol Oxidoreductases; Animals; Ethanol; Fatty Acids; Fatty Liver; Humans; Hyperlipidemias; Liver;

1976
[Rational therapy of liver diseases in general practice].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1976, Jan-20, Volume: 52, Issue:2

    Topics: Adult; Aged; Amino Acids; Chronic Disease; Drug Combinations; Fatty Liver; Female; Folic Acid; Hepat

1976
Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability.
    The Journal of nutrition, 1989, Volume: 119, Issue:10

    Topics: Animals; Biomarkers; Choline Deficiency; Cysteine; Diet; Fatty Liver; Folic Acid Deficiency; Glutath

1989
Studies on azaserine-induced fatty liver in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:1

    Topics: Acetates; Adenine Nucleotides; Adenosine Triphosphate; Animals; Azaserine; Biotin; Carbon Isotopes;

1970