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niacinamide and Experimental Mammary Neoplasms

niacinamide has been researched along with Experimental Mammary Neoplasms in 37 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
" nicotinamide, isonicotinamide or nicotinic acid, as extra (axial) ligands, were tested in vivo on transplanted mice tumors, namely Lewis lung carcinoma (3LL), melanoma B16, and mammary adenocarcinoma Ca755."3.72Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue. ( Bubnovskaya, L; Campanella, L; Ganusevich, I; Kovelskaya, A; Levitin, I; Osinsky, S; Sigan, A; Valkovskaya, N; Wardman, P, 2004)
"10 mmol/kg) and carbogen breathing, administered alone or in combination, were investigated on two tumour cell lines: EMT6 (a rodent mammary carcinoma) and HRT18 (a human rectal adenocarcinoma) using a clonogenic assay."3.69Efficacy of agents counteracting hypoxia in fractionated radiation regimes. ( Guichard, M; Stern, S, 1996)
"Sorafenib has shown clinical efficacy in treating solid tumours such as renal cell and hepatocellular carcinomas."1.38Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model. ( Deblois, F; Devic, S; Heravi, M; Holmes, J; Liang, L; Muanza, T; Radzioch, D; Tomic, N, 2012)
" The half-life of nicotinamide increased from 1."1.29Pharmacokinetics of varying doses of nicotinamide and tumour radiosensitisation with carbogen and nicotinamide: clinical considerations. ( Dennis, MF; Hodgkiss, RJ; Johns, H; Rojas, A; Stratford, MR, 1993)
" The elimination half-life and AUC were also found to increase with drug dose, although these increases were non-linear."1.29Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy. ( Dennis, IF; Honess, DJ; Horsman, MR; Høyer, M; Overgaard, J, 1993)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199010 (27.03)18.7374
1990's12 (32.43)18.2507
2000's7 (18.92)29.6817
2010's7 (18.92)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Bazhin, AA1
Sinisi, R1
De Marchi, U1
Hermant, A1
Sambiagio, N1
Maric, T1
Budin, G1
Goun, EA1
Santidrian, AF1
Matsuno-Yagi, A1
Ritland, M1
Seo, BB1
LeBoeuf, SE1
Gay, LJ1
Yagi, T1
Felding-Habermann, B1
An, H1
Stoops, SL1
Deane, NG1
Zhu, J1
Zi, J1
Weaver, C1
Waterson, AG1
Zijlstra, A1
Lindsley, CW1
Beauchamp, RD1
Wittenborn, TR1
Horsman, MR11
Mignion, L1
Danhier, P1
Magat, J1
Porporato, PE1
Masquelier, J1
Gregoire, V1
Muccioli, GG1
Sonveaux, P1
Gallez, B1
Jordan, BF1
Blazejczyk, A1
Switalska, M1
Chlopicki, S1
Marcinek, A1
Gebicki, J1
Nowak, M1
Nasulewicz-Goldeman, A1
Wietrzyk, J1
Sabir, A1
Schor-Bardach, R1
Wilcox, CJ1
Rahmanuddin, S1
Atkins, MB1
Kruskal, JB1
Signoretti, S1
Raptopoulos, VD1
Goldberg, SN1
Coxon, A1
Bush, T1
Saffran, D1
Kaufman, S1
Belmontes, B1
Rex, K1
Hughes, P1
Caenepeel, S1
Rottman, JB1
Tasker, A1
Patel, V1
Kendall, R1
Radinsky, R1
Polverino, A1
Heravi, M1
Tomic, N1
Liang, L1
Devic, S1
Holmes, J1
Deblois, F1
Radzioch, D1
Muanza, T1
Hammond, E1
Brandt, R1
Dredge, K1
DIETRICH, LS2
Overgaard, J9
Osinsky, S1
Levitin, I1
Bubnovskaya, L1
Sigan, A1
Ganusevich, I1
Kovelskaya, A1
Valkovskaya, N1
Campanella, L1
Wardman, P1
Rojas, A3
Stratford, MR2
Bentzen, SM1
Denekamp, J1
Jonsson, GG2
Kjellén, E4
Pero, RW4
Khalil, AA3
Chaplin, DJ6
Siemann, DW2
Nordsmark, M3
Grau, C1
Hill, SA2
Khalil, A1
Hodgkiss, RJ1
Dennis, MF1
Johns, H3
Rojas, AM1
Fiat, PR1
Høyer, M1
Honess, DJ1
Dennis, IF1
Hirst, DG1
Joiner, B1
Hirst, VK2
Calvert, AS1
Stern, S1
Guichard, M1
Ogawa, A1
Griffin, RJ1
Song, CW1
Braun, RD1
Lanzen, JL1
Turnage, JA1
Rosner, G1
Dewhirst, MW1
Lorimer, WS1
Stone, PR1
Kidwell, WR1
Kristjansen, PE1
Mizuno, M1
Christensen, KL1
Quistorff, B1
Brown, JM1
Hansen, PV1
Nilsson, P2
Cameron, R1
Muniz, O1
Farinas, B1
Franklin, L1
von Ardenne, M1
Chaplain, RA1

Other Studies

37 other studies available for niacinamide and Experimental Mammary Neoplasms

ArticleYear
A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential.
    Nature chemical biology, 2020, Volume: 16, Issue:12

    Topics: Adipocytes; Adipose Tissue, Brown; Aging; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazon

2020
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:3

    Topics: Acrylamides; Animals; Autophagy; Autophagy-Related Protein 5; Brain Neoplasms; Cell Line, Tumor; Cel

2013
Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition.
    Oncotarget, 2015, Sep-08, Volume: 6, Issue:26

    Topics: Animals; Cadherins; Cell Line, Tumor; Chick Embryo; Colorectal Neoplasms; Epithelial-Mesenchymal Tra

2015
Targeting tumour hypoxia to improve outcome of stereotactic radiotherapy.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Hypoxia; Diphosphates; Female; Hyperthermi

2015
Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.
    International journal of cancer, 2016, Apr-15, Volume: 138, Issue:8

    Topics: Animals; Antineoplastic Agents; Choline Kinase; Diffusion Magnetic Resonance Imaging; Female; Hetero

2016
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
    Journal of experimental & clinical cancer research : CR, 2016, 07-13, Volume: 35, Issue:1

    Topics: Animals; Cadherins; Cdh1 Proteins; Cell Line, Tumor; Epoprostenol; Female; Gene Expression Regulatio

2016
Perfusion MDCT enables early detection of therapeutic response to antiangiogenic therapy.
    AJR. American journal of roentgenology, 2008, Volume: 191, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzenesulfonates; Female; Mammary Neoplasm

2008
Broad antitumor activity in breast cancer xenografts by motesanib, a highly selective, oral inhibitor of vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jan-01, Volume: 15, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell

2009
Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model.
    Anti-cancer drugs, 2012, Volume: 23, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Cycle; Cell Di

2012
PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma model.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc

2012
AUGMENTATION OF 6-AMINONICOTINAMIDE ANTAGONISM OF TUMOR GROWTH BY COMPOUNDS WITH ESTROGENIC ACTIVITY.
    Cancer research, 1964, Volume: 24

    Topics: 6-Aminonicotinamide; Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Cortisone; Di

1964
Preclinical studies on how to deal with patient intolerance to nicotinamide and carbogen.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 70, Issue:3

    Topics: Animals; Carbon Dioxide; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Femal

2004
Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue.
    Experimental oncology, 2004, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinoma, Lewis Lung; Cobalt; DNA Damage; Ethylenediamines; Female; Hypoxi

2004
Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation?
    International journal of radiation biology, 2004, Volume: 80, Issue:7

    Topics: Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental;

2004
Nicotinamide as a radiosensitizer of a C3H mouse mammary adenocarcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1984, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; NAD; Niaci

1984
The ability of nicotinamide to inhibit the growth of a C3H mouse mammary carcinoma.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Division; Cyclohexanes; Dose-Response Relationship, Drug; Fatty

1995
The combination of nicotinamide and carbogen breathing to improve tumour oxygenation prior to radiation treatment.
    Advances in experimental medicine and biology, 1994, Volume: 361

    Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Mice; M

1994
Reoxygenation in a C3H mouse mammary carcinoma. The importance of chronic rather than acute hypoxia.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C

1995
Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:4

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Female; Mammary Neoplasms, Experimental; Mice; Niacinamide; O

1994
Tumour radiosensitization by nicotinamide: is it the result of an improvement in tumour oxygenation?
    Advances in experimental medicine and biology, 1994, Volume: 345

    Topics: Animals; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H;

1994
Pharmacokinetics of varying doses of nicotinamide and tumour radiosensitisation with carbogen and nicotinamide: clinical considerations.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Dr

1993
Should carbogen and nicotinamide be given throughout the full course of fractionated radiotherapy regimens?
    International journal of radiation oncology, biology, physics, 1993, Dec-01, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C

1993
Nicotinamide pharmacokinetics in humans and mice: a comparative assessment and the implications for radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 27, Issue:2

    Topics: Adult; Animals; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Mammary Neoplasms

1993
Blood flow modification by nicotinamide and metoclopramide in mouse tumours growing in different sites.
    British journal of cancer, 1993, Volume: 67, Issue:1

    Topics: Animals; Cardiac Output; Colonic Neoplasms; Male; Mammary Neoplasms, Experimental; Metoclopramide; M

1993
Carbogen and nicotinamide as radiosensitizers in a murine mammary carcinoma using conventional and accelerated radiotherapy.
    International journal of radiation oncology, biology, physics, 1996, Jan-15, Volume: 34, Issue:2

    Topics: Animals; Body Weight; Carbon Dioxide; Dose-Response Relationship, Radiation; Male; Mammary Neoplasms

1996
Efficacy of agents counteracting hypoxia in fractionated radiation regimes.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 41, Issue:2

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Emulsions; Female; Fluorocarbons; Humans; Hyd

1996
Effect of a combination of mild-temperature hyperthermia and nicotinamide on the radiation response of experimental tumors.
    Radiation research, 2000, Volume: 153, Issue:3

    Topics: Animals; Cell Division; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Radiat

2000
Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats.
    Radiation research, 2001, Volume: 155, Issue:5

    Topics: Animals; Arterioles; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Mammary Neoplasms, Experime

2001
Control of histone H1 dimer-poly(ADP-ribose) complex formation by poly(ADP-ribose) glycohydrolase.
    Experimental cell research, 1977, Volume: 106, Issue:2

    Topics: Animals; Breast Neoplasms; Cell Line; Cell Nucleus; Female; Glycoside Hydrolases; Histones; Humans;

1977
Biochemical and physiological changes induced by nicotinamide in a C3H mouse mammary carcinoma and CDF1 mice.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Blood Pressure; Fem

1992
Tumor radiosensitization by nicotinamide: a result of improved perfusion and oxygenation.
    Radiation research, 1989, Volume: 118, Issue:1

    Topics: Animals; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB

1989
Radiosensitization by nicotinamide in tumors and normal tissues: the importance of tissue oxygenation status.
    International journal of radiation oncology, biology, physics, 1989, Volume: 16, Issue:5

    Topics: Animals; Female; Male; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Niacinamide;

1989
Effect of hyperthermia and/or nicotinamide on the radiation response of a C3H mammary carcinoma.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:12

    Topics: Animals; Combined Modality Therapy; Female; Hyperthermia, Induced; Male; Mammary Neoplasms, Experime

1989
Comparison of low dose nicotinamide versus benzamide, administered per os, as radiosensitizers in a C3H mammary carcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1988, Volume: 12, Issue:4

    Topics: Administration, Oral; Animals; Benzamides; Combined Modality Therapy; Male; Mammary Neoplasms, Exper

1988
Radiosensitization effects of nicotinamide on malignant and normal mouse tissue.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Animals; Carbon Radioisotopes; Gamma Rays; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB

1985
6-aminonicotinamide-14C utilization by the 755 tumor and host liver tissue.
    Cancer research, 1968, Volume: 28, Issue:8

    Topics: Animals; Carbon Isotopes; Mammary Neoplasms, Experimental; Mice; Mitochondria, Liver; Niacinamide; N

1968
The inhibitory effect of B-group vitamins on the incidence of tumour metastases.
    Die Naturwissenschaften, 1971, Volume: 58, Issue:4

    Topics: Animals; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Niacinamide; Ox

1971