Page last updated: 2024-10-19

niacinamide and Erythema

niacinamide has been researched along with Erythema in 20 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"Our patient experienced a diffuse hyperkeratotic rash, hand-foot skin reaction, facial erythema, and stomatitis within three weeks of initiation of sorafenib."7.76Hyperkeratotic eruption, hand-foot skin reaction, facial erythema, and stomatitis secondary to multi-targeted kinase inhibitor sorafenib. ( Sahai, S; Swick, BL, 2010)
"A 60-year-old woman with recurrent papular and vesiculobullous lesions of erythema elevatum diutinum responded to treatment with 100 mg of oral niacinamide three times a day and 250 mg of tetracycline hydrochloride four times a day."7.66Erythema elevatum diutinum treated with niacinamide and tetracycline. ( Kohler, IK; Lorincz, AL, 1980)
"A patient with tuberculous meningitis developed a pellagra-like skin eruption after treatment with isoniazid."7.65Topically applied niacinamide in isoniazid-induced pellagra. ( Comaish, JS; Felix, RH; McGrath, H, 1976)
" Sorafenib and sunitinib are two of these novel agents, acting on tumour angiogenesis as well as on other key proliferative pathways; recently approved for the treatment of advanced kidney cancer, they may cause peculiar cutaneous, vascular and mucosal toxicities, including hand-foot skin reaction, skin rash, hypertension and GERD-like oesophagitis/gastritis."4.84Uncovering Pandora's vase: the growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib. ( Bonomi, L; Imarisio, I; Paglino, C; Porta, C, 2007)
"Our patient experienced a diffuse hyperkeratotic rash, hand-foot skin reaction, facial erythema, and stomatitis within three weeks of initiation of sorafenib."3.76Hyperkeratotic eruption, hand-foot skin reaction, facial erythema, and stomatitis secondary to multi-targeted kinase inhibitor sorafenib. ( Sahai, S; Swick, BL, 2010)
"A 60-year-old woman with recurrent papular and vesiculobullous lesions of erythema elevatum diutinum responded to treatment with 100 mg of oral niacinamide three times a day and 250 mg of tetracycline hydrochloride four times a day."3.66Erythema elevatum diutinum treated with niacinamide and tetracycline. ( Kohler, IK; Lorincz, AL, 1980)
"A patient with tuberculous meningitis developed a pellagra-like skin eruption after treatment with isoniazid."3.65Topically applied niacinamide in isoniazid-induced pellagra. ( Comaish, JS; Felix, RH; McGrath, H, 1976)
"Sorafenib is a targeted drug specifically engineered to inhibit Raf serine/threonine kinases, which are part of the reticular activating system (RAS) oncogene pathway."1.35Cutaneous drug eruptions induced by sorafenib: a case series. ( Kung, EF; Maddox, JS; Petronic-Rosic, V; Sethi, A, 2008)
"The incidence of skin cancer continues to increase despite increased use of sunscreens, which are less effective at preventing immunosuppression than sunburn."1.35UV radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide. ( Barnetson, RS; Damian, DL; Halliday, GM; Park, J; Patterson, CR; Stapelberg, M, 2008)
" We report the development of localized palmar-plantar epidermal hyperplasia, a rare but significant cutaneous adverse event from sorafenib therapy."1.34Localized palmar-plantar epidermal hyperplasia: a previously undefined dermatologic toxicity to sorafenib. ( Beldner, M; Burges, GE; Chaudhary, UB; Dewaay, D; Jacobson, M; Maize, JC, 2007)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's2 (10.00)18.2507
2000's7 (35.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akakpo, AS1
Saka, B1
Teclessou, JN1
Mouhari-Toure, A1
Moise Elegbede, Y1
Kombate, K1
Tchangai-Walla, K1
Pitche, P1
Ogawa, K1
Fukumoto, T1
Yoshida, M1
Matsumoto, Y1
Shobatake, C1
Asada, H1
Cicek, D1
Kandi, B1
Dagli, FA1
Karaoglu, A1
Haligur, BD1
Maddox, JS1
Kung, EF1
Petronic-Rosic, V1
Sethi, A1
Lipworth, AD1
Robert, C1
Zhu, AX1
Tanabe, K1
Amoh, Y1
Mii, S1
Eto, H1
Iwamura, M1
Katsuoka, K1
Sahai, S1
Swick, BL1
Rübsam, K1
Flaig, MJ1
Ruzicka, T1
Prinz, JC1
Dasanu, CA1
Alexandrescu, DT1
Dutcher, J1
Damian, DL1
Patterson, CR1
Stapelberg, M1
Park, J1
Barnetson, RS1
Halliday, GM1
Beldner, M1
Jacobson, M1
Burges, GE1
Dewaay, D1
Maize, JC1
Chaudhary, UB1
Porta, C1
Paglino, C1
Imarisio, I1
Bonomi, L1
Pérez-Bernal, A1
Moreno-Giménez, JC1
Sotillo-Gago, I1
Camacho-Martínez, F1
Kohler, IK1
Lorincz, AL1
Comaish, JS1
Felix, RH1
McGrath, H1
Yourick, JJ2
Dawson, JS1
Mitcheltree, LW2
Clark, CR1
Schmutz, JL1
Cuny, JF1
Trechot, P1
Weber, M1
Beurey, J1
Seidel, K1
Eckstein, M1
Ionescu, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Re-validating Prophylactic Efficacy of Urea-based Cream on Sorafenib-induced Hand-foot Skin Reaction in Patients With Advanced Hepatocellular Carcinoma[NCT04568330]129 participants (Actual)Interventional2014-03-21Completed
"Evaluation of the Restorative Efficacy of the Cosmetic Product Onco-Repair vs. Placebo on Grade 2 Hand Foot Syndrome Induced by Targeted Therapies or Conventional Chemotherapy. Randomized, Multicentre, Double Blind, Controlled Study Versus Placebo."[NCT03612011]Phase 372 participants (Actual)Interventional2018-07-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for niacinamide and Erythema

ArticleYear
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Hand-foot syndrome (hand-foot skin reaction, palmar-plantar erythrodysesthesia): focus on sorafenib and sunitinib.
    Oncology, 2009, Volume: 77, Issue:5

    Topics: Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Foot Dermatoses; Hand Dermatoses

2009
Uncovering Pandora's vase: the growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib.
    Clinical and experimental medicine, 2007, Volume: 7, Issue:4

    Topics: Acneiform Eruptions; Antineoplastic Agents; Benzenesulfonates; Erythema; Esophagitis; Exanthema; Hum

2007

Other Studies

18 other studies available for niacinamide and Erythema

ArticleYear
Pellagra and pellagra-like erythema in a hospital setting in Lomé, Togo : retrospective study from 1997 to 2017.
    Medecine et sante tropicales, 2019, Feb-01, Volume: 29, Issue:1

    Topics: Alcoholism; Diarrhea; Erythema; Female; Humans; Male; Malnutrition; Middle Aged; Niacinamide; Pellag

2019
Eosinophilic annular erythema in a patient with autoimmune pancreatitis: Nicotinamide therapy may be beneficial for achieving remission.
    The Journal of dermatology, 2016, Volume: 43, Issue:11

    Topics: Aged; Eosinophilia; Erythema; Humans; Male; Niacinamide; Pancreatitis; Skin Diseases, Genetic; Vitam

2016
Localized palmar-plantar epidermal hyperplasia associated with use of sorafenib.
    Clinical drug investigation, 2008, Volume: 28, Issue:12

    Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Eruptions; Erythema; Humans; K

2008
Cutaneous drug eruptions induced by sorafenib: a case series.
    Journal of drugs in dermatology : JDD, 2008, Volume: 7, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Drug Eruptions; Erythema; Female; Humans; Mid

2008
Non-pigmenting fixed drug eruption induced by sorafenib.
    Acta dermato-venereologica, 2010, Volume: 90, Issue:3

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Biopsy; Carcinoma, Renal Cell; Drug Eruptions; Eryth

2010
Hyperkeratotic eruption, hand-foot skin reaction, facial erythema, and stomatitis secondary to multi-targeted kinase inhibitor sorafenib.
    International journal of dermatology, 2010, Volume: 49, Issue:10

    Topics: Benzenesulfonates; Carcinoma, Renal Cell; Erythema; Humans; Kidney Neoplasms; Male; Middle Aged; Nia

2010
Erythema marginatum hemorrhagicum: a unique cutaneous side effect of sorafenib.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:6

    Topics: Aged; Benzenesulfonates; Carcinoma, Hepatocellular; Erythema; Hemorrhage; Humans; Liver Neoplasms; M

2011
Yellow skin discoloration associated with sorafenib use for treatment of metastatic renal cell carcinoma.
    Southern medical journal, 2007, Volume: 100, Issue:3

    Topics: Acrodermatitis; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Erythema; Humans; K

2007
UV radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:2

    Topics: Administration, Topical; Adult; Apoptosis; Complement System Proteins; Energy Metabolism; Erythema;

2008
Localized palmar-plantar epidermal hyperplasia: a previously undefined dermatologic toxicity to sorafenib.
    The oncologist, 2007, Volume: 12, Issue:10

    Topics: Adult; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Drug Eruptions; Erythema; Hu

2007
[Erythema elevatum et diutinum treated with nicotinamide and tetracyclines].
    Medicina cutanea ibero-latino-americana, 1983, Volume: 11, Issue:1

    Topics: Erythema; Humans; Male; Middle Aged; Niacinamide; Tetracycline

1983
Erythema elevatum diutinum treated with niacinamide and tetracycline.
    Archives of dermatology, 1980, Volume: 116, Issue:6

    Topics: Drug Therapy, Combination; Erythema; Female; Humans; Middle Aged; Niacinamide; Recurrence; Tetracycl

1980
Topically applied niacinamide in isoniazid-induced pellagra.
    Archives of dermatology, 1976, Volume: 112, Issue:1

    Topics: Administration, Topical; Adult; Erythema; Humans; Isoniazid; Male; Niacinamide; Pellagra; Tuberculos

1976
Sulfur mustard-induced microvesication in hairless guinea pigs: effect of short-term niacinamide administration.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:1

    Topics: Animals; Blister; Enzyme Activation; Erythema; Guinea Pigs; Male; Mustard Gas; NAD; Niacinamide; Pol

1992
Niacinamide pretreatment reduces microvesicle formation in hairless guinea pigs cutaneously exposed to sulfur mustard.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 17, Issue:3

    Topics: Animals; Biopsy; Edema; Erythema; Guinea Pigs; Male; Mustard Gas; NAD; Niacinamide; Skin

1991
[Drug-induced pellagroid erythema. A case of pellagroid erythema caused by isoniazide].
    Annales de dermatologie et de venereologie, 1987, Volume: 114, Issue:4

    Topics: Antineoplastic Agents; Erythema; Ethionamide; Female; Humans; Isoniazid; Middle Aged; Monoamine Oxid

1987
[Testing of the antiphlogistic effect of antirheumatic drugs].
    Munchener medizinische Wochenschrift (1950), 1966, Oct-14, Volume: 108, Issue:41

    Topics: Antipyrine; Arthritis, Rheumatoid; Drug Synergism; Erythema; Humans; Injections, Intramuscular; Niac

1966
[Vascular erythematous reaction by administration of vitamin PP (nicotinic acid). Demonstration of a pre- and post-clinical luetic roseola].
    Dermatologische Wochenschrift, 1966, Feb-19, Volume: 152, Issue:8

    Topics: Drug Eruptions; Erythema; Humans; Niacinamide; Syphilis, Cutaneous

1966