Page last updated: 2024-10-19

niacinamide and Epithelial Neoplasms

niacinamide has been researched along with Epithelial Neoplasms in 9 studies

nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

Research Excerpts

ExcerptRelevanceReference
"Patients with stage 3 or 4 epithelial ovarian cancer with residual measurable disease or elevated CA-125 levels after maximal surgical cytoreduction were randomized (1:1) to receive treatment with paclitaxel (175 mg/m(2) , 3 h infusion, day 1) and carboplatin (AUC 6."6.80Paclitaxel/carboplatin with or without sorafenib in the first-line treatment of patients with stage III/IV epithelial ovarian cancer: a randomized phase II study of the Sarah Cannon Research Institute. ( Bismayer, JA; Dudley, BS; Finney, LH; Gian, VG; Hainsworth, JD; Merritt, WM; Thompson, DS; Whorf, RC, 2015)
"Sorafenib was administered as 400 mg twice daily on days 1-28 of each 4-week cycle."6.76Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study. ( Bodnar, L; Górnas, M; Szczylik, C, 2011)
"Patients with stage 3 or 4 epithelial ovarian cancer with residual measurable disease or elevated CA-125 levels after maximal surgical cytoreduction were randomized (1:1) to receive treatment with paclitaxel (175 mg/m(2) , 3 h infusion, day 1) and carboplatin (AUC 6."2.80Paclitaxel/carboplatin with or without sorafenib in the first-line treatment of patients with stage III/IV epithelial ovarian cancer: a randomized phase II study of the Sarah Cannon Research Institute. ( Bismayer, JA; Dudley, BS; Finney, LH; Gian, VG; Hainsworth, JD; Merritt, WM; Thompson, DS; Whorf, RC, 2015)
"This study was designed to evaluate the response and toxicity of sorafenib alone or when combined with carboplatin and paclitaxel in patients with platinum-sensitive, recurrent ovarian cancer, fallopian tube cancer, or primary peritoneal cancer (EOC)."2.79Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer. ( Dowlati, A; Eaton, S; Frasure, H; Fu, P; Fusco, N; Schwandt, A; von Gruenigen, VE; Waggoner, S; Wenham, RM; Wright, JJ, 2014)
"Sorafenib was administered as 400 mg twice daily on days 1-28 of each 4-week cycle."2.76Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study. ( Bodnar, L; Górnas, M; Szczylik, C, 2011)
"Sorafenib is a novel oral anticancer agent targeting signal transduction and angiogenic pathways through inhibitory effects against MAP kinases and vascular endothelial growth factor receptor-2."2.75Sorafenib in combination with carboplatin and paclitaxel as neoadjuvant chemotherapy in patients with advanced ovarian cancer. ( Coch, C; Eckhardt, M; Hartmann, G; Kübler, K; Kuhn, W; Pölcher, M; Rudlowski, C; Wolfgarten, M, 2010)
"Intermittent sorafenib dosing with bevacizumab has promising clinical activity and less sorafenib dose reduction and side effects, but does not ameliorate HFSR."1.36Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity. ( Annunziata, CM; Azad, N; Houston, N; Kohn, EC; Kotz, H; Lee, JM; Minasian, L; Sarosy, GA; Squires, J, 2010)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwandt, A1
von Gruenigen, VE1
Wenham, RM1
Frasure, H1
Eaton, S1
Fusco, N1
Fu, P1
Wright, JJ1
Dowlati, A1
Waggoner, S1
Hainsworth, JD1
Thompson, DS1
Bismayer, JA1
Gian, VG1
Merritt, WM1
Whorf, RC1
Finney, LH1
Dudley, BS1
Mato, E1
Barceló-Batllori, S1
Orera, I1
Selva, L1
Corra, M1
González, C1
Bell, O1
Lerma, E1
Moral, A1
Pérez, JI1
de Leiva, A1
Simonelli, M1
Zucali, PA2
Suter, MB1
Lorenzi, E1
Rubino, L1
Fatuzzo, G1
Alloisio, M1
Santoro, A2
Lee, JM1
Sarosy, GA1
Annunziata, CM2
Azad, N1
Minasian, L2
Kotz, H1
Squires, J1
Houston, N1
Kohn, EC2
Pölcher, M1
Eckhardt, M1
Coch, C1
Wolfgarten, M1
Kübler, K1
Hartmann, G1
Kuhn, W1
Rudlowski, C1
Bodnar, L1
Górnas, M1
Szczylik, C1
Petrini, I1
Meltzer, PS1
Luo, J1
Lee, C1
Lee, HS1
Killian, KJ1
Wang, Y2
Tsokos, M1
Roncalli, M1
Steinberg, SM2
Giaccone, G1
Azad, NS1
Premkumar, A1
Chow, C1
Kotz, HL1

Reviews

1 review available for niacinamide and Epithelial Neoplasms

ArticleYear
Targeted therapy for thymic epithelial tumors: a new horizon? Review of the literature and two cases reports.
    Future oncology (London, England), 2015, Volume: 11, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; ErbB Receptors; Female; Histone Deacetylase In

2015

Trials

5 trials available for niacinamide and Epithelial Neoplasms

ArticleYear
Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer.
    Investigational new drugs, 2014, Volume: 32, Issue:4

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma,

2014
Paclitaxel/carboplatin with or without sorafenib in the first-line treatment of patients with stage III/IV epithelial ovarian cancer: a randomized phase II study of the Sarah Cannon Research Institute.
    Cancer medicine, 2015, Volume: 4, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino

2015
Sorafenib in combination with carboplatin and paclitaxel as neoadjuvant chemotherapy in patients with advanced ovarian cancer.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carboplatin; Early T

2010
Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study.
    Gynecologic oncology, 2011, Volume: 123, Issue:1

    Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Ovarian Epithelial; Disease-Free Survival

2011
Lack of reliability of CA125 response criteria with anti-VEGF molecularly targeted therapy.
    Cancer, 2008, Apr-15, Volume: 112, Issue:8

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineopl

2008

Other Studies

3 other studies available for niacinamide and Epithelial Neoplasms

ArticleYear
The proteomic 2D-DIGE approach reveals the protein voltage-dependent anion channel 2 as a potential therapeutic target in epithelial thyroid tumours.
    Molecular and cellular endocrinology, 2015, Mar-15, Volume: 404

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associ

2015
Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity.
    British journal of cancer, 2010, Feb-02, Volume: 102, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2010
Copy number aberrations of BCL2 and CDKN2A/B identified by array-CGH in thymic epithelial tumors.
    Cell death & disease, 2012, Jul-19, Volume: 3

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aniline Compounds; Animals; Apoptosis Regulatory Protein

2012