niacinamide has been researched along with Epilepsy, Absence in 2 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Absence epilepsy is generated by the cortico-thalamo-cortical network, which undergoes a finely tuned regulation by metabotropic glutamate (mGlu) receptors." | 1.39 | Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats. ( Biagioni, F; Conn, PJ; D'Amore, V; Jones, CK; Lindsley, CW; Molinaro, G; Ngomba, RT; Nicoletti, F; Prete, A; Rodriguez, AL; Santolini, I; Stauffer, SR; van Luijtelaar, G; van Rijn, CM; Vinson, PN; Zhou, Y, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Amore, V | 2 |
| Santolini, I | 2 |
| Celli, R | 1 |
| Lionetto, L | 1 |
| De Fusco, A | 1 |
| Simmaco, M | 1 |
| van Rijn, CM | 2 |
| Vieira, E | 1 |
| Stauffer, SR | 2 |
| Conn, PJ | 2 |
| Bosco, P | 1 |
| Nicoletti, F | 2 |
| van Luijtelaar, G | 2 |
| Ngomba, RT | 2 |
| Biagioni, F | 1 |
| Molinaro, G | 1 |
| Prete, A | 1 |
| Lindsley, CW | 1 |
| Zhou, Y | 1 |
| Vinson, PN | 1 |
| Rodriguez, AL | 1 |
| Jones, CK | 1 |
2 other studies available for niacinamide and Epilepsy, Absence
| Article | Year |
|---|---|
Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Cerebral Cortex; Disease Models, Animal; Drug Tolerance | 2014 |
Potentiation of mGlu5 receptors with the novel enhancer, VU0360172, reduces spontaneous absence seizures in WAG/Rij rats.
Topics: Age Factors; Animals; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electroencephalography; | 2013 |