niacinamide has been researched along with Endotoxemia in 11 studies
nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lethal endotoxemia was induced by intraperitoneal administration of LPS at a dose of 20 mg/kg." | 1.38 | Therapeutic benefits of the group B3 vitamin nicotinamide in mice with lethal endotoxemia and polymicrobial sepsis. ( Ge, P; Li, H; Li, L; Wan, J; Yuan, H; Zhang, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lenglet, A | 1 |
| Fabresse, N | 1 |
| Taupin, M | 1 |
| Gomila, C | 1 |
| Liabeuf, S | 1 |
| Kamel, S | 1 |
| Alvarez, JC | 1 |
| Drueke, TB | 1 |
| Massy, ZA | 1 |
| Zarubina, IV | 1 |
| Yunusov, IA | 1 |
| Marysheva, VV | 1 |
| Shabanov, PD | 1 |
| Yuan, H | 1 |
| Wan, J | 1 |
| Li, L | 1 |
| Ge, P | 1 |
| Li, H | 1 |
| Zhang, L | 1 |
| Bagnenko, SF | 1 |
| Mirzabaev, AT | 1 |
| Batotsyrenov, BV | 1 |
| Gorbachev, NB | 1 |
| Miroshnichenko, VN | 1 |
| Batotsyrenova, KhV | 1 |
| Velikiĭ, KF | 1 |
| Ungerstedt, JS | 1 |
| Blömback, M | 1 |
| Söderström, T | 1 |
| Scharte, M | 1 |
| Nofer, JR | 1 |
| Aken, HV | 1 |
| Waurick, R | 1 |
| Meyer, J | 1 |
| Bone, HG | 1 |
| Stehr, A | 2 |
| Ploner, F | 2 |
| Tugtekin, I | 2 |
| Matejovic, M | 2 |
| Theisen, M | 2 |
| Zülke, C | 1 |
| Georgieff, M | 2 |
| Radermacher, P | 2 |
| Jauch, KW | 1 |
| Soop, A | 1 |
| Albert, J | 1 |
| Weitzberg, E | 1 |
| Bengtsson, A | 1 |
| Nilsson, CG | 1 |
| Sollevi, A | 1 |
| Wray, GM | 1 |
| Hinds, CJ | 1 |
| Thiemermann, C | 1 |
| Pulido, EJ | 1 |
| Shames, BD | 1 |
| Selzman, CH | 1 |
| Barton, HA | 1 |
| Banerjee, A | 1 |
| Bensard, DD | 1 |
| McIntyre, RC | 1 |
| Träger, K | 1 |
3 trials available for niacinamide and Endotoxemia
| Article | Year |
|---|---|
Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?
Topics: Aged; Endotoxemia; Endotoxins; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Human | 2019 |
[Pharmacological correction of free radical disturbances and endotoxicosis in patients with diffuse peritonitis at the postoperative period].
Topics: Adult; Antioxidants; Drug Combinations; Endotoxemia; Female; Flavin Mononucleotide; Free Radicals; H | 2011 |
Nicotinamide does not influence cytokines or exhaled NO in human experimental endotoxaemia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Breath Tests; Cross-Over Studies; Cytokines; Double- | 2004 |
8 other studies available for niacinamide and Endotoxemia
| Article | Year |
|---|---|
Comparative efficiency of succinate-containing antihypoxants in traumatic toxicosis.
Topics: Animals; Antioxidants; Drug Combinations; Endotoxemia; Flavin Mononucleotide; Inosine Diphosphate; I | 2010 |
Therapeutic benefits of the group B3 vitamin nicotinamide in mice with lethal endotoxemia and polymicrobial sepsis.
Topics: Animals; Endotoxemia; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred BALB C; Niacinamide; Seps | 2012 |
Nicotinamide is a potent inhibitor of proinflammatory cytokines.
Topics: Adjuvants, Immunologic; Cells, Cultured; Cytokines; Depression, Chemical; Dose-Response Relationship | 2003 |
Nicotinamide increases systemic vascular resistance in ovine endotoxemia.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Disease Mode | 2003 |
Effect of combining nicotinamide as a PARS-inhibitor with selective iNOS blockade during porcine endotoxemia.
Topics: Amidines; Animals; Benzylamines; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, | 2003 |
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidne | 1998 |
Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation.
Topics: Adenosine Triphosphate; Animals; Benzamides; Cyclic GMP; Endotoxemia; Endotoxins; Enzyme Inhibitors; | 1999 |
Effects of nicotinamide, an inhibitor of PARS activity, on gut and liver O2 exchange and energy metabolism during hyperdynamic porcine endotoxemia.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Disease Models, Animal; Drug Evaluation | 2001 |